Selective Impairment

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Elizabeth K. Warrington - One of the best experts on this subject based on the ideXlab platform.

  • Past, present, and prospects: Reflections 40 years on from the Selective Impairment of semantic memory (Warrington, 1975)
    Quarterly journal of experimental psychology (2006), 2015
    Co-Authors: Rosaleen A. Mccarthy, Elizabeth K. Warrington
    Abstract:

    We summarize the main findings and conclusions of Warrington's (1975) paper, The Selective Impairment of Semantic memory, a neuropsychological paper that described three cases with degenerative neurological conditions [Warrington, E. K. (1975). The Selective Impairment of semantic memory. The Quarterly Journal of Experimental Psychology, 27, 635–657]. We consider the developments that have followed from its publication and give a Selective overview of the field in 2014. The initial impact of the paper was on neuropsychological investigations of semantic loss followed some 14 years later by the identification of Semantic Dementia (the condition shown by the original cases) as a distinctive form of degenerative disease with unique clinical and pathological characteristics. We discuss the distinction between disorders of semantic storage and refractory semantic access, the evidence for category- and modality-specific Impairments of semantics, and the light that has been shed on the structure and organization...

  • Countries: Their Selective Impairment and Selective preservation
    Neurocase, 1998
    Co-Authors: Antonio Incisa Della Rocchetta, Lisa Cipolotti, Elizabeth K. Warrington
    Abstract:

    Abstract We present two cases that argue for a further fractionation of semantic knowledge in the category of proper names. In both patients the provisional diagnosis was progressive dementia, Alzheimer's (patient DK) and Pick's (patient TM) respectively. Patient DK was Selectively impaired in naming and comprehending countries within the visual modality. Thus, he was unable to name a country from its map or to point to it on the map from its spoken name, whilst being able to name that same country promptly from verbal description. His naming and comprehension were intact for famous people's names and for all other categories of knowledge tested. By contrast, patient TM's naming and comprehension of people's names and all categories except for countries were profoundly impaired. We show that his Impairment is limited to the verbal modality. We conclude that the observed category by modality interaction can be accommodated best by the multiple semantics hypothesis. Thus, countries are Selectively impaired ...

  • Topographical Disorientation: Selective Impairment of Locomotor Space?
    Cortex; a journal devoted to the study of the nervous system and behavior, 1996
    Co-Authors: Antonio Incisa Della Rocchetta, Lisa Cipolotti, Elizabeth K. Warrington
    Abstract:

    Abstract We report a single-case study of a patient who suddenly lost her ability to orient herself in her neighbourhood. On formal testing she demonstrated remarkably Selective deficits in episodic and semantic memory of topographical items and routes. Her general intellectual abilities were unaffected as were basic perceptual processes and episodic and semantic memory other than topography. We interpret her deficit as a further example of category-specific processing Impairment affecting knowledge acquired through Selective channels - in this case visuo-locomotor information.

  • Selective Impairment of memory and visual perception in splenial tumours
    Brain, 1991
    Co-Authors: Peter Rudge, Elizabeth K. Warrington
    Abstract:

    The neuropsychological abnormalities found in 9 patients with tumours involving the splenium of the corpus callosum are described. The outstanding features of their cognitive deficits were a severe memory deficit and visual perception Impairment in the presence of relatively intact intellect. It is argued that (1) the amnesia is due to damage to the fornix where that structure is closely applied to the splenium and that it is the result of a disconnection between the frontal and temporal lobes, although the possibility that damage to more than one structure, for example, retrosplenial cortex and fornix, cannot be excluded; (2) there is a dual pathway for visual object recognition, one of which passes directly to the dominant hemisphere for semantic analysis and the other via the nondominant hemisphere for prior perceptual analysis. Further, it is postulated that there is a subcortical as well as a callosal route between the hemispheres that is important for visual object recognition.

Sharon Abrahams - One of the best experts on this subject based on the ideXlab platform.

  • Selective Impairment in visual short-term memory binding
    Cognitive neuropsychology, 2009
    Co-Authors: Mario A. Parra, Sergio Della Sala, Robert H. Logie, Sharon Abrahams
    Abstract:

    Dissociations within binding in perception have been reported after brain damage. In short-term memory (STM), feature binding and feature processing appear to rely on separate processes. However, dissociations within binding in STM following brain damage have not been reported to date. We report on the case E.S. who, after removal of a left medial sphenoid ridge meningioma, developed a Selective Impairment of visual STM (VSTM) binding. We found that, despite having normal perceptual binding, E.S. was unable to retain in VSTM features bound into objects while she could retain individual features as well as controls did (Experiments 1-2, 4, and 6). Her verbal STM for bound and single features remains intact (Experiments 3 and 5). E.S.'s performance suggests that STM binding can be dissociated from STM for single features across visual and verbal domains. The results are discussed in the light of current models of STM.

Antonella Zadini - One of the best experts on this subject based on the ideXlab platform.

Mario A. Parra - One of the best experts on this subject based on the ideXlab platform.

  • Selective Impairment in visual short-term memory binding
    Cognitive neuropsychology, 2009
    Co-Authors: Mario A. Parra, Sergio Della Sala, Robert H. Logie, Sharon Abrahams
    Abstract:

    Dissociations within binding in perception have been reported after brain damage. In short-term memory (STM), feature binding and feature processing appear to rely on separate processes. However, dissociations within binding in STM following brain damage have not been reported to date. We report on the case E.S. who, after removal of a left medial sphenoid ridge meningioma, developed a Selective Impairment of visual STM (VSTM) binding. We found that, despite having normal perceptual binding, E.S. was unable to retain in VSTM features bound into objects while she could retain individual features as well as controls did (Experiments 1-2, 4, and 6). Her verbal STM for bound and single features remains intact (Experiments 3 and 5). E.S.'s performance suggests that STM binding can be dissociated from STM for single features across visual and verbal domains. The results are discussed in the light of current models of STM.

H. Valerie Curran - One of the best experts on this subject based on the ideXlab platform.

  • Decreases in recollective experience following acute alcohol: a dose–response study
    Psychopharmacology, 2009
    Co-Authors: James A. Bisby, Julie R. Leitz, Celia J. A. Morgan, H. Valerie Curran
    Abstract:

    Rationale Acute alcohol intoxication induces a Selective Impairment of recognition memory associated with conscious recollection whilst recognition based on familiarity is left intact.

  • Selective Impairment in the recognition of anger induced by diazepam.
    Psychopharmacology, 1999
    Co-Authors: Robert James Blair, H. Valerie Curran
    Abstract:

    Rationale: Facial expressions appear to be processed by at least partially separable neuro-cognitive systems. Given this functional specialisation of expression processing, it is plausible that these neurocognitive systems may also be dissociable pharmacologically. Objective: The present study therefore compared the effects of diazepam (15 mg) with placebo upon the ability to recognise emotional expressions. Methods: A double blind, independent group design was used to compare the effects of diazepam and matched placebo in 32 healthy volunteers. Participants were presented morphed facial expression stimuli following a paradigm developed for use with patients with brain damage and asked to name one of the six basic emotions (sadness, happiness, anger, disgust, fear and surprise). Results: Diazepam Selectively impaired subjects' ability to recognise angry expressions but did not affect recognition of any other emotional expression. Conclusions: The findings are interpreted as providing further support for the suggestion that there are dissociable systems responsible for processing emotional expressions. It is suggested that these findings may have implications for understanding paradoxical aggression sometimes elicited by benzodiazepines.