The Experts below are selected from a list of 102 Experts worldwide ranked by ideXlab platform

Babs Taal - One of the best experts on this subject based on the ideXlab platform.

  • Imaging and retention measurements of Selenium 75 homocholic acid conjugated with taurine, and the carbon 14 glycochol breath test to document ileal dysfunction due to late radiation damage
    European Journal of Nuclear Medicine, 1991
    Co-Authors: R Valdes Olmos, Frieda Hartog Jager, Cornelis Hoefnagel, Babs Taal
    Abstract:

    In order to assess ileal dysfunction in patients with complaints after pelvic radiation therapy, retention measurements and scintigraphic imaging with Selenium 75 homocholic acid conjugated with taurine (^75Se-HCAT), combined with the carbon 14 glycochol breath test, were evaluated in 39 patients. In 22 patients without ileal resection the results of the^75Se-HCAT test and the breath test differentiated between a normal functioning ileum (both tests negative) and ileal dysfunction as a cause of complaints (one or both tests positive). Among the patients with ileal dysfunction, the combination of both tests permitted those with bacterial overgrowth (breath test positive,^75Se-HCAT negative) to be separated from patients with evidence of bile acid malabsorption (^75Se-HCAT positive, breath test positive or negative). In 17 patients with small-bowel resection, the^75Se-HCAT test helped to estimate the severity of bile acid malabsorption with implications for therapy. In this group the breath test was false-negative in 7 cases with abnormal^75Se-HCAT. Additional systematically performed scintigraphic imaging improved the accuracy of the^75Se-HCAT test, revealing cases with prolonged colonic accumulation of the radiopharmaceutical, causing spurious retention values. In conclusion, assessment of ileal dysfunction by nuclear medicine techniques in post-irradiation conditions provides information about the aetiology and therefore the possibility of adjustment in the clinical management.

R Valdes Olmos - One of the best experts on this subject based on the ideXlab platform.

  • Imaging and retention measurements of Selenium 75 homocholic acid conjugated with taurine, and the carbon 14 glycochol breath test to document ileal dysfunction due to late radiation damage
    European Journal of Nuclear Medicine, 1991
    Co-Authors: R Valdes Olmos, Frieda Hartog Jager, Cornelis Hoefnagel, Babs Taal
    Abstract:

    In order to assess ileal dysfunction in patients with complaints after pelvic radiation therapy, retention measurements and scintigraphic imaging with Selenium 75 homocholic acid conjugated with taurine (^75Se-HCAT), combined with the carbon 14 glycochol breath test, were evaluated in 39 patients. In 22 patients without ileal resection the results of the^75Se-HCAT test and the breath test differentiated between a normal functioning ileum (both tests negative) and ileal dysfunction as a cause of complaints (one or both tests positive). Among the patients with ileal dysfunction, the combination of both tests permitted those with bacterial overgrowth (breath test positive,^75Se-HCAT negative) to be separated from patients with evidence of bile acid malabsorption (^75Se-HCAT positive, breath test positive or negative). In 17 patients with small-bowel resection, the^75Se-HCAT test helped to estimate the severity of bile acid malabsorption with implications for therapy. In this group the breath test was false-negative in 7 cases with abnormal^75Se-HCAT. Additional systematically performed scintigraphic imaging improved the accuracy of the^75Se-HCAT test, revealing cases with prolonged colonic accumulation of the radiopharmaceutical, causing spurious retention values. In conclusion, assessment of ileal dysfunction by nuclear medicine techniques in post-irradiation conditions provides information about the aetiology and therefore the possibility of adjustment in the clinical management.

Cornelis Hoefnagel - One of the best experts on this subject based on the ideXlab platform.

  • Imaging and retention measurements of Selenium 75 homocholic acid conjugated with taurine, and the carbon 14 glycochol breath test to document ileal dysfunction due to late radiation damage
    European Journal of Nuclear Medicine, 1991
    Co-Authors: R Valdes Olmos, Frieda Hartog Jager, Cornelis Hoefnagel, Babs Taal
    Abstract:

    In order to assess ileal dysfunction in patients with complaints after pelvic radiation therapy, retention measurements and scintigraphic imaging with Selenium 75 homocholic acid conjugated with taurine (^75Se-HCAT), combined with the carbon 14 glycochol breath test, were evaluated in 39 patients. In 22 patients without ileal resection the results of the^75Se-HCAT test and the breath test differentiated between a normal functioning ileum (both tests negative) and ileal dysfunction as a cause of complaints (one or both tests positive). Among the patients with ileal dysfunction, the combination of both tests permitted those with bacterial overgrowth (breath test positive,^75Se-HCAT negative) to be separated from patients with evidence of bile acid malabsorption (^75Se-HCAT positive, breath test positive or negative). In 17 patients with small-bowel resection, the^75Se-HCAT test helped to estimate the severity of bile acid malabsorption with implications for therapy. In this group the breath test was false-negative in 7 cases with abnormal^75Se-HCAT. Additional systematically performed scintigraphic imaging improved the accuracy of the^75Se-HCAT test, revealing cases with prolonged colonic accumulation of the radiopharmaceutical, causing spurious retention values. In conclusion, assessment of ileal dysfunction by nuclear medicine techniques in post-irradiation conditions provides information about the aetiology and therefore the possibility of adjustment in the clinical management.

Frieda Hartog Jager - One of the best experts on this subject based on the ideXlab platform.

  • Imaging and retention measurements of Selenium 75 homocholic acid conjugated with taurine, and the carbon 14 glycochol breath test to document ileal dysfunction due to late radiation damage
    European Journal of Nuclear Medicine, 1991
    Co-Authors: R Valdes Olmos, Frieda Hartog Jager, Cornelis Hoefnagel, Babs Taal
    Abstract:

    In order to assess ileal dysfunction in patients with complaints after pelvic radiation therapy, retention measurements and scintigraphic imaging with Selenium 75 homocholic acid conjugated with taurine (^75Se-HCAT), combined with the carbon 14 glycochol breath test, were evaluated in 39 patients. In 22 patients without ileal resection the results of the^75Se-HCAT test and the breath test differentiated between a normal functioning ileum (both tests negative) and ileal dysfunction as a cause of complaints (one or both tests positive). Among the patients with ileal dysfunction, the combination of both tests permitted those with bacterial overgrowth (breath test positive,^75Se-HCAT negative) to be separated from patients with evidence of bile acid malabsorption (^75Se-HCAT positive, breath test positive or negative). In 17 patients with small-bowel resection, the^75Se-HCAT test helped to estimate the severity of bile acid malabsorption with implications for therapy. In this group the breath test was false-negative in 7 cases with abnormal^75Se-HCAT. Additional systematically performed scintigraphic imaging improved the accuracy of the^75Se-HCAT test, revealing cases with prolonged colonic accumulation of the radiopharmaceutical, causing spurious retention values. In conclusion, assessment of ileal dysfunction by nuclear medicine techniques in post-irradiation conditions provides information about the aetiology and therefore the possibility of adjustment in the clinical management.

Heinz H. Coenen - One of the best experts on this subject based on the ideXlab platform.