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Lifeng Han - One of the best experts on this subject based on the ideXlab platform.
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new anthraquinone and eurotinone analogue from the seeds of Senna obtusifolia and their inhibitory effects on human organic anion transporters 1 and 3
Natural Product Research, 2019Co-Authors: Xu Pang, Liming Wang, Youcai Zhang, Liping Kang, Guanwei Fan, Lifeng HanAbstract:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6’-O-α,β-unsaturated butyryl...
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New anthraquinone and eurotinone analogue from the seeds of Senna obtusifolia and their inhibitory effects on human organic anion transporters 1 and 3
2018Co-Authors: Xu Pang, Liming Wang, Youcai Zhang, Liping Kang, Guanwei Fan, Lifeng HanAbstract:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6’-O-α,β-unsaturated butyryl)-glucopyranoside (1) and a new eurotinone analogue, epi-9-dehydroxyeurotinone-β-D-glucopyranoside (2). Their structures were established mainly by NMR and MS experiments as well as the necessary chemical evidences. Their inhibitory effects on two organic anion transporters (OAT1 and OAT3) were investigated and the results showed that 1 exhibited a strongly specific inhibitory effect on OAT1 at 100 μM.
Zewdu K. Tessema - One of the best experts on this subject based on the ideXlab platform.
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Effect of Senna obtusifolia (L.) invasion on herbaceous vegetation and soil properties of rangelands in the western Tigray, northern Ethiopia
Ecological Processes, 2018Co-Authors: Maru G. Gebrekiros, Zewdu K. TessemaAbstract:Introduction Invasion of exotic plant species is a well-known threat to native ecosystems since it directly affects native plant communities by altering their composition and diversity. Moreover, exotic plant species displace native species through competition, changes in ecosystem processes, or allelopathic effects. Senna obtusifolia (L.) invasion has affected the growth and productivity of herbaceous vegetation in semi-arid regions of northern Ethiopia. Here, we investigated the species composition, species diversity, aboveground biomass, and basal cover of herbaceous vegetation, as well as soil properties of rangelands along three S. obtusifolia invasion levels. Methods Herbaceous vegetation and soil properties were studied at two locations, Kafta Humera and Tsegede districts, in the western Tigray region of northern Ethiopia under three levels of S. obtusifolia invasion, i.e., non-invaded, lightly invaded, and heavily invaded. Herbaceous plant species composition and their abundance were assessed using a 1-m^2 quadrat during the flowering stage of most herbaceous species from mid-August to September 2015. Native species were classified into different functional groups and palatability classes, which can be useful in understanding mechanisms underlying the differential responses of native plants to invasion. The percentage of basal cover for S. obtusifolia and native species and that of bare ground were estimated in each quadrat. Similar to sampling of the herbaceous species, soil samples at a depth of 0–20 cm were taken for analyzing soil physical and chemical properties. Results Highly palatable grasses and legumes based on the frequency of occurrence were 1.9 and 3.8 times higher in non-invaded sites than in lightly and heavily invaded sites, respectively. Furthermore, unpalatable plant species were 4.0 times higher in the heavily invaded sites than in the lightly invaded sites. Aboveground biomass, basal cover, and species diversity of the herbaceous vegetation were significantly ( P
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effect of Senna obtusifolia l invasion on herbaceous vegetation and soil properties of rangelands in the western tigray northern ethiopia
Ecological processes, 2018Co-Authors: Maru G. Gebrekiros, Zewdu K. TessemaAbstract:Invasion of exotic plant species is a well-known threat to native ecosystems since it directly affects native plant communities by altering their composition and diversity. Moreover, exotic plant species displace native species through competition, changes in ecosystem processes, or allelopathic effects. Senna obtusifolia (L.) invasion has affected the growth and productivity of herbaceous vegetation in semi-arid regions of northern Ethiopia. Here, we investigated the species composition, species diversity, aboveground biomass, and basal cover of herbaceous vegetation, as well as soil properties of rangelands along three S. obtusifolia invasion levels. Herbaceous vegetation and soil properties were studied at two locations, Kafta Humera and Tsegede districts, in the western Tigray region of northern Ethiopia under three levels of S. obtusifolia invasion, i.e., non-invaded, lightly invaded, and heavily invaded. Herbaceous plant species composition and their abundance were assessed using a 1-m2 quadrat during the flowering stage of most herbaceous species from mid-August to September 2015. Native species were classified into different functional groups and palatability classes, which can be useful in understanding mechanisms underlying the differential responses of native plants to invasion. The percentage of basal cover for S. obtusifolia and native species and that of bare ground were estimated in each quadrat. Similar to sampling of the herbaceous species, soil samples at a depth of 0–20 cm were taken for analyzing soil physical and chemical properties. Highly palatable grasses and legumes based on the frequency of occurrence were 1.9 and 3.8 times higher in non-invaded sites than in lightly and heavily invaded sites, respectively. Furthermore, unpalatable plant species were 4.0 times higher in the heavily invaded sites than in the lightly invaded sites. Aboveground biomass, basal cover, and species diversity of the herbaceous vegetation were significantly (P < 0.01) lower in the heavily invaded sites compared to the non-invaded sites. However, most soil properties were not affected by S. obtusifolia invasion compared with non-invaded sites in our study. Our findings contribute towards better understanding of how S. obtusifolia invasion affects the community structure and composition of native herbaceous vegetation in semi-arid rangelands in northern Ethiopia. Further long-term studies are required to understand the mechanisms of how S. obtusifolia invasion influences soil properties for better control and eradication of its invasion in the semi-arid rangelands of northern Ethiopia.
C Augustine - One of the best experts on this subject based on the ideXlab platform.
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nutrient digestibility and growth performance of cockerels fed processed sickle pod Senna obtusifolia seed meal based diets
Nigerian Journal of Animal Production, 2020Co-Authors: C Augustine, I.d. Kwari, J.u. Igwebuikwe, S.b. Adamu, C.i. Medugu, D Khobe, D M Babale, L U ObidahAbstract:A Feeding trial was conducted for sixteen weeks to evaluate nutrient utilization and growth performanceofcockerelsfedprocessedSennaobtusifoliamealbased-diets.Sixexperimental diets werecompounded tocontain 0%and20%eachoftheraw,boiled, soaked, sproutedand fermented Senna obtusifolia seed meal designated T1, T2, T3, T4, T5 and T6, respectively. Data were collected on nutrient digestibility, feed intake, weight gain, feed conversion ratio and mortality. Poor nutrient digestibility for crude protein (45.18%), nitrogen free extract (42.39%) and ether extract (49.22%) were recorded in the group of cockerels fed raw Senna obtusifolia seed meal based-diet. However, better nutrient digestibility for crude protein (76.23%), nitrogen free extract (67.62%) and ether extract (68.65%) digestibility was observed in the group of cockerel fed 0% Senna obtusifolia seed meal based-diet. Among the cockerels fed the processed Senna obtusifolia seed meal based-diets, those fed the fermented Senna obtusifolia seed meal based-diet showed better crude protein (75.08%), ether extract (68.65%) nitrogen free exract (67.62%) and crude fibre (32.78%) digestibility. The result of productive performance revealed a significantly (P<0.05) low total feed intake (3242.13 g), total weight gain (806.50 g) and the poorest feed conversion ratio(4.02) in the group of cockerels fed raw Senna obtusifolia seed meal based-diet. The group of cockerels fed the processed Senna obtusifolia seed meal based-diets indicated significant (P<0.05) improvement in productive performance with those fed the fermented Senna obtusifolia seed meal based-diet recording the highest total feed intake (3552.51 g), total weight gain (1079.79 g) and the best feed conversion ratio (3.29). It can be concluded that 20% of fermented Senna obtusifolia seed meal can be incorporated in the diets of cockerels without depreciationinnutrientdigestibilityandproductiveperformance.
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laying performance and cost benefits of feeding isa brown layers with raw or processed tropical sickle pod Senna obtusifolia seed meal based diets
Nigerian Journal of Animal Science, 2019Co-Authors: C Augustine, I.d. Kwari, J.u. Igwebuikwe, S.b. Adamu, A D Faci, S Ahmed, Y M Garba, D.i. MojabaAbstract:A feeding trial was conducted for 16 weeks to evaluate the effects and cost-benefits of feeding raw or processed Senna obtusifolia seed meal based-diets on the laying performance of ISA brown laying hens. Six experimental diets were compounded to contain 0% S. obtusifolia seed meal (T1) and 20% each of the raw, boiled, soaked in water, sprouted and fermented S. obtusifolia seed meals designated as T2, T3, T4, T5 and T6, respectively. One hundred and eighty (180) ISA brown laying hens aged 36 weeks were housed in battery cages (5 birds/0.95 m2) and assigned to the six (6) dietary treatments in group of thirty (30) laying hens in a completely randomized design. Data was collected on feed intake, hen-day egg production (HDEP), hen-house egg production (HHEP), egg weight, egg mass, feed conversion ratio per egg mass, feed cost per kilogram, feed cost per egg mass and mortality. The results indicated that the group of hens fed raw S. obtusifolia seed meal based-diet recorded the lowest HDEP (52.42%), egg weight (53.08 g) and egg mass (2782.45 g). Among the laying hens fed the processed S. obtusifolia seed rneal based-diets, those fed the fermented S. obtusifolia seed meal based-diet indicated significantly (P<0.05) better HDEP (64.05%), egg weight (59.75 g) and egg mass (3826.98 g). On economic grounds, the use of raw S. obtusifolia seed meal is not cost effective but the processed ones showed some economic advantage. In conclusion, 20% of fermented S. obtusifolia seed meal can be incorporated in the diets of laying hens with little or no depreciation in laying performance and economic-benefits. Keywords: Laying hens, laying performance, processed sickle pod, cost-benefits
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Laying performance and cost-benefits of feeding brown laying hens with raw or processed tropical sickle pod (Senna obtusifolia) seed meal based-diets
Trakia University. Faculty of Agriculture Stara Zagora, 2018Co-Authors: C Augustine, I.d. Kwari, J.u. Igwebuikwe, S.b. Adamu, C.i. Medugu, D.i. MojabaAbstract:Abstract. . A feeding trial was conducted for 16 weeks to evaluate the effects and cost-benefits of feeding raw or processed Senna obtusifolia (S. obtusifolia) seed meal based-diets on the laying performance of ISA brown laying hens. Six experimental diets were compounded to contain 0% S. obtusifolia seed meal (T1) and 20% each of the raw, boiled, soaked, sprouted and fermented S. obtusifolia seed meals designated as T2, T3, T4, T5 and T6, respectively. One hundred and eighty (180) ISA brown laying hens aged 36 weeks were housed in battery cages (5 birds/0.95m2) and assigned to the six (6) dietary treatments in groups of thirty (30) birds in a completely randomized design. Each replicate cage contains 10 laying hens. Data were collected on feed intake, hen-day egg production (HDEP), hen-house egg production (HHEP), egg weight, egg mass, feed conversion ratio per egg mass, feed cost per kilogram, feed cost per egg mass and mortality. The results indicated that the group of laying hens fed raw S. obtusifolia seed meal based diet recorded the lowest HDEP (52.42%), egg weight (53.08g) and egg mass (2782.45g). Among the hens fed the processed S. obtusifolia seed meal based diets, the laying hens fed the fermented S. obtusifolia seed meal based diet indicated significantly (p
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nutrient digestibility and growth performance of broiler chickens fed processed tropical sicklepod Senna obtusifolia l seed meal based diets
Journal of Agricultural Sciences Belgrade, 2017Co-Authors: C Augustine, D I Kwari, U J Igwebuike, B S Adamu, Siaka S DiarraAbstract:The eight-week feeding trial was conducted to evaluate the nutrient digestibility and growth performance of broiler chickens fed raw or processed Senna obtusifolia seed meal (SOSM). Six experimental diets were compounded to contain 0% SOSM and 20% each of the raw, boiled, soaked, sprouted and fermented SOSM respectively. Two hundred and sixteen (216) broiler chicks were randomly allotted to six (6) dietary treatments in a randomised complete block design with three (3) replicates containing 12 chicks each. Data were collected on nutrient digestibility, feed intake, weight gain, feed conversion ratio and mortality. The result of productive performance indicated that feed intake, weight gain and feed conversion ratio were significantly (P<0.05) depressed in broiler chickens fed raw, soaked and sprouted Senna obtusifolia seed meal. However, broiler chickens fed fermented SOSM showed better (P<0.05) productive performance that was close to those fed the positive control diet (0% SOSM). The mortality rate did not reveal any particular trend. However, the low mortality rate recorded in the different treatments indicated broiler chicken can tolerate up to 20% of either raw or processed SOSM. Broiler chickens fed raw SOSM recorded lower values for dry matter (63.06%), crude protein (52.46%), ether extract (53.88%), crude fibre (30.72%) and nitrogen-free extract (46.11%) digestibility than those fed the other processed SOSM. The nutrient digestibility of broiler chickens fed fermented SOSM was significantly (P<0.05) better followed by those fed boiled Senna obtusifolia seed meal. For instance, broiler chickens fed fermented Senna obtusifolia seed meal recorded the highest crude protein and ether extract of 69.91 and 70.03% compared to the other processing methods. It can be concluded that 20% fermented SOSM can be incorporated in the diets of broiler chickens with acceptable depreciation in biological performance. Slightly lower levels of boiled SOSM can be included in the diet of broiler chickens but the levels should be ascertained in further studies.
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Evaluation of chemical composition of raw and processed tropical sickle pod (Senna obtusifolia) seed meal
Trakia University. Faculty of Agriculture Stara Zagora, 2017Co-Authors: C Augustine, Kwari I.d., Igwebuike J.u., S.b. AdamuAbstract:Abstract. A laboratory analysis was conducted to evaluate the chemical composition of raw and differently processed Senna obtusifolia seed meal. Senna obtusifolia seeds were processed using boiling, soaking, sprouting and fermentation methods respectively. The processed and raw seed meals were milled and the representative seed meal samples were analysed using standard laboratory methods. The results of the chemical analysis revealed that Senna obtusifolia seed meal possessed good nutritional properties (23.40 – 25.90% crude protein and 2.14 – 2.86 MJ/kg metabolizable energy) and has good amino acid profile as an alternative feed source for livestock. However, the raw seed meal contains 378.5, 247.2, 102.0, 248.6 and 190.0 mg/100.0g of tannins, phytates, oxalate, alkaloids and saponins, respectively. The different processing methods were observed to be effective in reducing the level of the antinutrients with fermentation recording the highest reduction levels of 68.25, 66.32, 43.70, 58.07 and 44.30% for tannins, phytates, oxalate, alkaloids and saponins followed by boiling with reduction levels of 66.27, 46.97, 46.97, 47.89, 58.66 and 45.78% for tannins, phytates, oxalate, alkaloids and saponins, respectively. In conclusion, Senna obtusifolia seed can be effectively process for utilization as feed ingredient using fermentation. Feeding trial should be conducted using Senna obtusifolia seed meal to evaluate the feeding value in livestock especially monogastric animal
Xu Pang - One of the best experts on this subject based on the ideXlab platform.
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new anthraquinone and eurotinone analogue from the seeds of Senna obtusifolia and their inhibitory effects on human organic anion transporters 1 and 3
Natural Product Research, 2019Co-Authors: Xu Pang, Liming Wang, Youcai Zhang, Liping Kang, Guanwei Fan, Lifeng HanAbstract:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6’-O-α,β-unsaturated butyryl...
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New anthraquinone and eurotinone analogue from the seeds of Senna obtusifolia and their inhibitory effects on human organic anion transporters 1 and 3
2018Co-Authors: Xu Pang, Liming Wang, Youcai Zhang, Liping Kang, Guanwei Fan, Lifeng HanAbstract:A continuous phytochemical study on the seeds of Senna obtusifolia (Syn.: Cassia obtusifolia) led to the isolation of a new anthraquinone analogue, obtusifolin-2-O-β-D-(6’-O-α,β-unsaturated butyryl)-glucopyranoside (1) and a new eurotinone analogue, epi-9-dehydroxyeurotinone-β-D-glucopyranoside (2). Their structures were established mainly by NMR and MS experiments as well as the necessary chemical evidences. Their inhibitory effects on two organic anion transporters (OAT1 and OAT3) were investigated and the results showed that 1 exhibited a strongly specific inhibitory effect on OAT1 at 100 μM.
S.b. Adamu - One of the best experts on this subject based on the ideXlab platform.
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nutrient digestibility and growth performance of cockerels fed processed sickle pod Senna obtusifolia seed meal based diets
Nigerian Journal of Animal Production, 2020Co-Authors: C Augustine, I.d. Kwari, J.u. Igwebuikwe, S.b. Adamu, C.i. Medugu, D Khobe, D M Babale, L U ObidahAbstract:A Feeding trial was conducted for sixteen weeks to evaluate nutrient utilization and growth performanceofcockerelsfedprocessedSennaobtusifoliamealbased-diets.Sixexperimental diets werecompounded tocontain 0%and20%eachoftheraw,boiled, soaked, sproutedand fermented Senna obtusifolia seed meal designated T1, T2, T3, T4, T5 and T6, respectively. Data were collected on nutrient digestibility, feed intake, weight gain, feed conversion ratio and mortality. Poor nutrient digestibility for crude protein (45.18%), nitrogen free extract (42.39%) and ether extract (49.22%) were recorded in the group of cockerels fed raw Senna obtusifolia seed meal based-diet. However, better nutrient digestibility for crude protein (76.23%), nitrogen free extract (67.62%) and ether extract (68.65%) digestibility was observed in the group of cockerel fed 0% Senna obtusifolia seed meal based-diet. Among the cockerels fed the processed Senna obtusifolia seed meal based-diets, those fed the fermented Senna obtusifolia seed meal based-diet showed better crude protein (75.08%), ether extract (68.65%) nitrogen free exract (67.62%) and crude fibre (32.78%) digestibility. The result of productive performance revealed a significantly (P<0.05) low total feed intake (3242.13 g), total weight gain (806.50 g) and the poorest feed conversion ratio(4.02) in the group of cockerels fed raw Senna obtusifolia seed meal based-diet. The group of cockerels fed the processed Senna obtusifolia seed meal based-diets indicated significant (P<0.05) improvement in productive performance with those fed the fermented Senna obtusifolia seed meal based-diet recording the highest total feed intake (3552.51 g), total weight gain (1079.79 g) and the best feed conversion ratio (3.29). It can be concluded that 20% of fermented Senna obtusifolia seed meal can be incorporated in the diets of cockerels without depreciationinnutrientdigestibilityandproductiveperformance.
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laying performance and cost benefits of feeding isa brown layers with raw or processed tropical sickle pod Senna obtusifolia seed meal based diets
Nigerian Journal of Animal Science, 2019Co-Authors: C Augustine, I.d. Kwari, J.u. Igwebuikwe, S.b. Adamu, A D Faci, S Ahmed, Y M Garba, D.i. MojabaAbstract:A feeding trial was conducted for 16 weeks to evaluate the effects and cost-benefits of feeding raw or processed Senna obtusifolia seed meal based-diets on the laying performance of ISA brown laying hens. Six experimental diets were compounded to contain 0% S. obtusifolia seed meal (T1) and 20% each of the raw, boiled, soaked in water, sprouted and fermented S. obtusifolia seed meals designated as T2, T3, T4, T5 and T6, respectively. One hundred and eighty (180) ISA brown laying hens aged 36 weeks were housed in battery cages (5 birds/0.95 m2) and assigned to the six (6) dietary treatments in group of thirty (30) laying hens in a completely randomized design. Data was collected on feed intake, hen-day egg production (HDEP), hen-house egg production (HHEP), egg weight, egg mass, feed conversion ratio per egg mass, feed cost per kilogram, feed cost per egg mass and mortality. The results indicated that the group of hens fed raw S. obtusifolia seed meal based-diet recorded the lowest HDEP (52.42%), egg weight (53.08 g) and egg mass (2782.45 g). Among the laying hens fed the processed S. obtusifolia seed rneal based-diets, those fed the fermented S. obtusifolia seed meal based-diet indicated significantly (P<0.05) better HDEP (64.05%), egg weight (59.75 g) and egg mass (3826.98 g). On economic grounds, the use of raw S. obtusifolia seed meal is not cost effective but the processed ones showed some economic advantage. In conclusion, 20% of fermented S. obtusifolia seed meal can be incorporated in the diets of laying hens with little or no depreciation in laying performance and economic-benefits. Keywords: Laying hens, laying performance, processed sickle pod, cost-benefits
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Laying performance and cost-benefits of feeding brown laying hens with raw or processed tropical sickle pod (Senna obtusifolia) seed meal based-diets
Trakia University. Faculty of Agriculture Stara Zagora, 2018Co-Authors: C Augustine, I.d. Kwari, J.u. Igwebuikwe, S.b. Adamu, C.i. Medugu, D.i. MojabaAbstract:Abstract. . A feeding trial was conducted for 16 weeks to evaluate the effects and cost-benefits of feeding raw or processed Senna obtusifolia (S. obtusifolia) seed meal based-diets on the laying performance of ISA brown laying hens. Six experimental diets were compounded to contain 0% S. obtusifolia seed meal (T1) and 20% each of the raw, boiled, soaked, sprouted and fermented S. obtusifolia seed meals designated as T2, T3, T4, T5 and T6, respectively. One hundred and eighty (180) ISA brown laying hens aged 36 weeks were housed in battery cages (5 birds/0.95m2) and assigned to the six (6) dietary treatments in groups of thirty (30) birds in a completely randomized design. Each replicate cage contains 10 laying hens. Data were collected on feed intake, hen-day egg production (HDEP), hen-house egg production (HHEP), egg weight, egg mass, feed conversion ratio per egg mass, feed cost per kilogram, feed cost per egg mass and mortality. The results indicated that the group of laying hens fed raw S. obtusifolia seed meal based diet recorded the lowest HDEP (52.42%), egg weight (53.08g) and egg mass (2782.45g). Among the hens fed the processed S. obtusifolia seed meal based diets, the laying hens fed the fermented S. obtusifolia seed meal based diet indicated significantly (p
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Evaluation of chemical composition of raw and processed tropical sickle pod (Senna obtusifolia) seed meal
Trakia University. Faculty of Agriculture Stara Zagora, 2017Co-Authors: C Augustine, Kwari I.d., Igwebuike J.u., S.b. AdamuAbstract:Abstract. A laboratory analysis was conducted to evaluate the chemical composition of raw and differently processed Senna obtusifolia seed meal. Senna obtusifolia seeds were processed using boiling, soaking, sprouting and fermentation methods respectively. The processed and raw seed meals were milled and the representative seed meal samples were analysed using standard laboratory methods. The results of the chemical analysis revealed that Senna obtusifolia seed meal possessed good nutritional properties (23.40 – 25.90% crude protein and 2.14 – 2.86 MJ/kg metabolizable energy) and has good amino acid profile as an alternative feed source for livestock. However, the raw seed meal contains 378.5, 247.2, 102.0, 248.6 and 190.0 mg/100.0g of tannins, phytates, oxalate, alkaloids and saponins, respectively. The different processing methods were observed to be effective in reducing the level of the antinutrients with fermentation recording the highest reduction levels of 68.25, 66.32, 43.70, 58.07 and 44.30% for tannins, phytates, oxalate, alkaloids and saponins followed by boiling with reduction levels of 66.27, 46.97, 46.97, 47.89, 58.66 and 45.78% for tannins, phytates, oxalate, alkaloids and saponins, respectively. In conclusion, Senna obtusifolia seed can be effectively process for utilization as feed ingredient using fermentation. Feeding trial should be conducted using Senna obtusifolia seed meal to evaluate the feeding value in livestock especially monogastric animal
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Haematological and serum biochemical indices of broiler chickens fed raw sickle pod (Senna obtusifolia) seed meal
Trakia University. Faculty of Agriculture Stara Zagora, 2017Co-Authors: C Augustine, I.d. Kwar, J.u. Igwebuike, S.b. AdamuAbstract:Abstract. A feeding trial was conducted for sixty three (63) days (9 weeks) to evaluate the effects of feeding raw Senna obtusifolia seed meal (RSOSM) on haematological indices and serum biochemical parameters of broiler chickens. Six experimental diets were compounded for both the starter (23% crude protein - CP) and finisher (20% CP) phases of growth. The diets were formulated to contain 0, 5, 10, 15, 20 and 25% level of raw Senna obtusifolia seed meal replacing roasted soya bean weight for weight in T , T , T , T , T and T respectively. The 0% replacement level (T1) served as the control diet. The broiler 1 2 3 4 5 6, 2 chickens were managed on deep litter pens of 30 birds/2.22 m , weighed and randomly allotted to the six (6) dietary treatments in a randomized complete block design (RCBD). Each treatment group consisted of thirty (30) broiler chicks replicated three times with ten (10) broiler chicks per replicate. Blood samples were collected from the wing vein at the end of the experiment using standard procedure and were analysed for haematological and biochemical profile. The outcome of this study revealed that the haematological indices were not significantly (P>0.05) affected by the dietary treatments. However, the blood chemistry was significantly (P
