Septal Panniculitis

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Christopher B. Bunker - One of the best experts on this subject based on the ideXlab platform.

  • Panniculitis with pseudomonas septicaemia in AIDS
    Journal of the European Academy of Dermatology and Venereology, 2006
    Co-Authors: Ruth A. Smith, Janet S. Ross, Anthony C. Branfoot, David Asboe, David C. Shanson, Brian Gazzard, Christopher B. Bunker
    Abstract:

    A 27 year old female with acquired immunodeficiency syndrome (AIDS) developed tender erythematous nodules on her thighs. A skin biopsy of the lesions showed Septal Panniculitis and venulitis and Pseudomonas species was cultured from both the urine and the skin biopsy tissue. The lesions resolved on antibiotic therapy. Panniculitic nodules may represent an early stage of ecthyma gangrenosum which is a well recognised cutaneous complication of pseudomonas septicaemia.

  • Case reportPanniculitis with pseudomonas septicaemia in AIDS
    Journal of the European Academy of Dermatology and Venereology, 1995
    Co-Authors: Ruth A. Smith, Janet S. Ross, Anthony C. Branfoot, David Asboe, David C. Shanson, Brian Gazzard, Christopher B. Bunker
    Abstract:

    A 27 year old female with acquired immunodeficiency syndrome (AIDS) developed tender erythematous nodules on her thighs. A skin biopsy of the lesions showed Septal Panniculitis and venulitis and Pseudomonas species was cultured from both the urine and the skin biopsy tissue. The lesions resolved on antibiotic therapy. Panniculitic nodules may represent an early stage of ecthyma gangrenosum which is a well recognised cutaneous complication of pseudomonas septicaemia.

Evaristo Sánchez Yus - One of the best experts on this subject based on the ideXlab platform.

  • Panniculitis. Part I. Mostly Septal Panniculitis
    Journal of the American Academy of Dermatology, 2001
    Co-Authors: Luis Requena, Evaristo Sánchez Yus
    Abstract:

    Abstract The panniculitides represent a group of heterogeneous inflammatory diseases that involve the subcutaneous fat. The specific diagnosis of these diseases requires histopathologic study because different panniculitides usually show the same clinical appearance, which consists of subcutaneous erythematous nodules on the lower extremities. However, the histopathologic study of Panniculitis is difficult because of an inadequate clinicopathologic correlation, and the changing evolutionary nature of the lesions means that biopsy specimens are often taken from late-stage lesions, which results in nonspecific histopathologic findings. In addition, large-scalpel incisional biopsies are required. However, we believe that by obtaining appropriate biopsy specimens and with adequate clinicopathologic correlation, a specific diagnosis may be rendered in most cases of Panniculitis. It must be accepted that all panniculitides are somewhat mixed because the inflammatory infiltrate involves both the septa and lobules; however, in general the differential diagnosis between a mostly Septal and a mostly lobular Panniculitis is straightforward at scanning magnification. Mostly Septal panniculitides with vasculitis include leukocytoclastic vasculitis involving the small blood vessels of the septa; superficial thrombophlebitis resulting from inflammation and subsequent thrombosis of large veins of the septa; and cutaneous polyarteritis nodosa, which is a vasculitis involving arteries and arterioles of the septa of subcutaneous fat with few or no systemic manifestations. Often Septal panniculitides with no vasculitis are the consequence of dermal inflammatory processes extending to the subcutaneous fat, such as necrobiosis lipoidica, scleroderma, subcutaneous granuloma annulare, rheumatoid nodule, and necrobiotic xanthogranuloma. However, in other cases, the inflammatory process is primarily located in the fibrous septa of the subcutis with or without involvement of the overlying dermis. The most frequently seen Septal Panniculitis is erythema nodosum, which, in fully developed lesions, is characterized histopathologically by Miescher's radial granulomas in the septa. (J Am Acad Dermatol 2001;45:163-83.) Learning objective: At the completion of this learning activity, participants should be familiar with the pathogenesis, clinical manifestations, histopathologic findings, and treatment options for the most frequent variants of the Septal panniculitides.

  • Erythema nodosum versus nodular vasculitis.
    International journal of dermatology, 1993
    Co-Authors: Maria-dolores Sanz Vico, Victor De Diego, Evaristo Sánchez Yus
    Abstract:

    Background. Erythema nodosum (en) is usually considered to be a Septal Panniculitis, and nodular vasculitis (nv) a lobular Panniculitis. We tested the usefulness of this histologic classification in clarifying a frequent clinical dilemma: en versus nv. Methods. Over 3 years 109 patients with Panniculitis were included in this study. After a history and a physical examination, a clinical diagnosis was made according to well-established criteria. Results. From the study of 88 patients, we concluded that in the clinically typical cases, the clinico-pathologic agreement was 93% and 94% for en and nv respectively, whereas it diminished to 79%, 72%, and 67% in the cases clinically diagnosed as en migrans, atypical en, and atypical nv, respectively. Moreover, Septal and lobular Panniculitis were always two clear-cut, different, opposite patterns of hypodermal inflammation to these conditions. Conclusions. In the absence of a known pathogenetic mechanism, the histopathology remains the most objective discriminating marker between en and nv, mainly in the clinically atypical and doubtful cases.

Franco Gennaro - One of the best experts on this subject based on the ideXlab platform.

  • Erythema nodosum induced by kerion celsi of the scalp in a woman.
    Mycoses, 2010
    Co-Authors: Morrone Aldo, Calcaterra Roberta, Valenzano Mariacarla, Fazio Raffaella, Franco Gennaro
    Abstract:

    Summary A 35-year-old woman, with a 3-week history of an enlarging erythematous, scaly plaque of the scalp vertex associated with the onset of some painful, subcutaneous nodules on her pretibial regions. Trichophyton mentagrophytes was isolated from the scalp lesion and the histological examination of one of the nodular lesions of the legs showed a Septal Panniculitis. The diagnosis of erythema nodosum (EN) induced by kerion celsi was made and the patient started therapy with oral terbinafine 250 mg per day for 4 weeks associated with naproxene per os 1 g per day for 2 weeks. Erythema nodosum is considered a reaction pattern to a wide variety of microbial and non-microbial stimuli: dermatophytic infections are rarely associated with EN.

Ruth A. Smith - One of the best experts on this subject based on the ideXlab platform.

  • Panniculitis with pseudomonas septicaemia in AIDS
    Journal of the European Academy of Dermatology and Venereology, 2006
    Co-Authors: Ruth A. Smith, Janet S. Ross, Anthony C. Branfoot, David Asboe, David C. Shanson, Brian Gazzard, Christopher B. Bunker
    Abstract:

    A 27 year old female with acquired immunodeficiency syndrome (AIDS) developed tender erythematous nodules on her thighs. A skin biopsy of the lesions showed Septal Panniculitis and venulitis and Pseudomonas species was cultured from both the urine and the skin biopsy tissue. The lesions resolved on antibiotic therapy. Panniculitic nodules may represent an early stage of ecthyma gangrenosum which is a well recognised cutaneous complication of pseudomonas septicaemia.

  • Case reportPanniculitis with pseudomonas septicaemia in AIDS
    Journal of the European Academy of Dermatology and Venereology, 1995
    Co-Authors: Ruth A. Smith, Janet S. Ross, Anthony C. Branfoot, David Asboe, David C. Shanson, Brian Gazzard, Christopher B. Bunker
    Abstract:

    A 27 year old female with acquired immunodeficiency syndrome (AIDS) developed tender erythematous nodules on her thighs. A skin biopsy of the lesions showed Septal Panniculitis and venulitis and Pseudomonas species was cultured from both the urine and the skin biopsy tissue. The lesions resolved on antibiotic therapy. Panniculitic nodules may represent an early stage of ecthyma gangrenosum which is a well recognised cutaneous complication of pseudomonas septicaemia.

Soyun Cho - One of the best experts on this subject based on the ideXlab platform.

  • A Case of Assisted Reproductive Therapy-induced Erythema Nodosum.
    Annals of dermatology, 2011
    Co-Authors: Hye Chan Jeon, Mira Choi, Seung Hwan Paik, Jong Hee Lee, Soyun Cho
    Abstract:

    Erythema nodosum is a common variant of Panniculitis. It is characterized by tender erythematous nodule and plaque on the anterior aspect of the leg. The etiology is not fully understood. It may be associated with a variety of disorders, including infection, medication, autoimmune disorders, pregnancy, and malignancy. A 33-year-old Korean woman presented with 1 week history of painful erythematous plaques on both knees. She was 7 weeks pregnant with assisted reproductive therapy, and had been maintained on daily intramuscular progesterone injection for 4 weeks. Histological examination of the lesions revealed Septal Panniculitis without vasculitis. Two days after discontinuing progesterone injection, the symptoms and lesions started to resolve. Herein we present a case of erythema nodosum caused by progesterone injection for endometrial preparation.

  • CASE REPORT A Case of Assisted Reproductive Therapy-induced
    2010
    Co-Authors: Erythema Nodosum, Hye Chan Jeon, Mira Choi, Seung Hwan Paik, Jong Hee Lee, Soyun Cho
    Abstract:

    Erythema nodosum is a common variant of Panniculitis. It is characterized by tender erythematous nodule and plaque on the anterior aspect of the leg. The etiology is not fully understood. It may be associated with a variety of disorders, including infection, medication, autoimmune disorders, pregnancy, and malignancy. A 33-year-old Korean woman presented with 1 week history of painful erythematous plaques on both knees. She was 7 weeks pregnant with assisted reproductive therapy, and had been maintained on daily intramuscular progesterone injection for 4 weeks. Histological examination of the lesions revealed Septal Panniculitis without vasculitis. Two days after discontinuing progesterone injection, the symptoms and lesions started to resolve. Herein we present a case of erythema nodosum caused by progesterone injection for endometrial preparation