Septic Thrombophlebitis

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Rogelio Pérez-padilla - One of the best experts on this subject based on the ideXlab platform.

  • Catheter-related Septic Thrombophlebitis of the great central veins successfully treated with low-dose streptokinase thrombolysis and antimicrobials
    Thrombosis Journal, 2005
    Co-Authors: Patricia Volkow, Patricia Cornejo-juárez, Ana Berta Arizpe-bravo, Jorge García-méndez, Enrique Baltazares-lipp, Rogelio Pérez-padilla
    Abstract:

    Background Septic Thrombophlebitis is an iatrogenic life-threatening disease associated with use of central venous devices and intravenous (IV) therapy. In cancer patients receiving chemotherapy, vein resection or surgical thrombectomy in large central venous lines is time-consuming, can delay administration of chemotherapy, and therefore can compromise tumor control. Experience with thrombolysis has been published for catheter-related thrombosis but for Septic thrombosis, this experience is scarce. Results We describe three patients with cancer and Septic Thrombophlebitis of central veins caused by Staphylococcus aureus treated with catheter removal, thrombolysis, and intravenous (IV) antibiotics. In our reported cases, an initial bolus of 250,000 international units (IU) of streptokinase administered during the first h followed by an infusion of 20,000–40,000 IU/h for 24–36 h through a proximal peripheral vein was sufficient to dissolve the thrombus. After thrombolyisis and parenteral antibiotic for 4–6 weeks the Septic thrombosis due to Staphylococcus aureus solved in all cases. No surgical procedure was needed, and potential placement of a catheter in the same vein was permitted. Conclusion Thrombolysis with streptokinase solved symptoms, cured infection, prevented embolus, and in all cases achieved complete thrombus lysis, avoiding permanent central-vein occlusion.

  • Catheter-related Septic Thrombophlebitis of the great central veins successfully treated with low-dose streptokinase thrombolysis and antimicrobials
    Thrombosis journal, 2005
    Co-Authors: Patricia Volkow, Patricia Cornejo-juárez, Ana Berta Arizpe-bravo, Jorge García-méndez, Enrique Baltazares-lipp, Rogelio Pérez-padilla
    Abstract:

    Background Septic Thrombophlebitis is an iatrogenic life-threatening disease associated with use of central venous devices and intravenous (IV) therapy. In cancer patients receiving chemotherapy, vein resection or surgical thrombectomy in large central venous lines is time-consuming, can delay administration of chemotherapy, and therefore can compromise tumor control. Experience with thrombolysis has been published for catheter-related thrombosis but for Septic thrombosis, this experience is scarce.

Jacques Durand-gasselin - One of the best experts on this subject based on the ideXlab platform.

  • Surgical management of Candida suppurative Thrombophlebitis of superior vena cava after central venous catheterization
    Intensive care medicine, 1997
    Co-Authors: E. Garcia, Isabelle Granier, A Geissler, M. D. Boespflug, P. E. Magnan, Jacques Durand-gasselin
    Abstract:

    Septic deep venous thrombosis is a major complication associated with central venous catheterization in intensive care units. The most common causative organisms are Staphylococcus aureus, gram-negative bacilli and Candida species. The incidence of Candida infections is increasing, especially in intensive care patients receiving total parenteral nutrition and long-term broad-spectrum antibiotics. Although intravascular catheter-induced Septic Thrombophlebitis is quite common, superior vena cava obstruction is a rare complication. However, few data exist concerning the best strategy for managing Septic Thrombophlebitis, especially when medical therapy fails. We report successful surgical management of Candida albicans suppurative thrombosis of the superior vena cava in a young patient.

Patricia Volkow - One of the best experts on this subject based on the ideXlab platform.

  • Catheter-related Septic Thrombophlebitis of the great central veins successfully treated with low-dose streptokinase thrombolysis and antimicrobials
    Thrombosis Journal, 2005
    Co-Authors: Patricia Volkow, Patricia Cornejo-juárez, Ana Berta Arizpe-bravo, Jorge García-méndez, Enrique Baltazares-lipp, Rogelio Pérez-padilla
    Abstract:

    Background Septic Thrombophlebitis is an iatrogenic life-threatening disease associated with use of central venous devices and intravenous (IV) therapy. In cancer patients receiving chemotherapy, vein resection or surgical thrombectomy in large central venous lines is time-consuming, can delay administration of chemotherapy, and therefore can compromise tumor control. Experience with thrombolysis has been published for catheter-related thrombosis but for Septic thrombosis, this experience is scarce. Results We describe three patients with cancer and Septic Thrombophlebitis of central veins caused by Staphylococcus aureus treated with catheter removal, thrombolysis, and intravenous (IV) antibiotics. In our reported cases, an initial bolus of 250,000 international units (IU) of streptokinase administered during the first h followed by an infusion of 20,000–40,000 IU/h for 24–36 h through a proximal peripheral vein was sufficient to dissolve the thrombus. After thrombolyisis and parenteral antibiotic for 4–6 weeks the Septic thrombosis due to Staphylococcus aureus solved in all cases. No surgical procedure was needed, and potential placement of a catheter in the same vein was permitted. Conclusion Thrombolysis with streptokinase solved symptoms, cured infection, prevented embolus, and in all cases achieved complete thrombus lysis, avoiding permanent central-vein occlusion.

  • Catheter-related Septic Thrombophlebitis of the great central veins successfully treated with low-dose streptokinase thrombolysis and antimicrobials
    Thrombosis journal, 2005
    Co-Authors: Patricia Volkow, Patricia Cornejo-juárez, Ana Berta Arizpe-bravo, Jorge García-méndez, Enrique Baltazares-lipp, Rogelio Pérez-padilla
    Abstract:

    Background Septic Thrombophlebitis is an iatrogenic life-threatening disease associated with use of central venous devices and intravenous (IV) therapy. In cancer patients receiving chemotherapy, vein resection or surgical thrombectomy in large central venous lines is time-consuming, can delay administration of chemotherapy, and therefore can compromise tumor control. Experience with thrombolysis has been published for catheter-related thrombosis but for Septic thrombosis, this experience is scarce.

Jose Luis Grueso - One of the best experts on this subject based on the ideXlab platform.

  • Septic Thrombophlebitis of the superior mesenteric vein and multiple liver abscesses in a patient with crohn s disease at onset
    BMC Gastroenterology, 2007
    Co-Authors: Mariam Aguas, Guillermo Bastida, Pilar Nos, Belen Beltran, Jose Luis Grueso
    Abstract:

    Portal-mesenteric vein thrombosis, pylephlebitis and liver abscesses are rare complications of inflammatory bowel disease (IBD). The purpose of this case report is to relate an unusual presentation of CD in order to show how conservative treatment could be an appropriate option as a bridge to the surgery, in patients with Septic Thrombophlebitis and multiple liver abscesses with CD. We report a case of a 25-year-old man with Crohn's disease (CD) who developed a superior mesenteric venous thrombosis, multiple liver abscesses and pylephlebitis, diagnosed through abdominal ultrasound and an abdominal computed tomography (CT) scan. The patient was successfully treated with conservative treatment consisting of intravenous antibiotics, subcutaneous anticoagulation and percutaneous catheter drainage of liver abscesses. We reported an unnusual case of pylephlebitis in CD. Until now this association has not been reported in adult patients at onset. We hypothesise that the infection developed as a result of mucosal disease and predisposed by corticoid therapy. Adequated management was discussed.

Enrique Baltazares-lipp - One of the best experts on this subject based on the ideXlab platform.

  • Catheter-related Septic Thrombophlebitis of the great central veins successfully treated with low-dose streptokinase thrombolysis and antimicrobials
    Thrombosis Journal, 2005
    Co-Authors: Patricia Volkow, Patricia Cornejo-juárez, Ana Berta Arizpe-bravo, Jorge García-méndez, Enrique Baltazares-lipp, Rogelio Pérez-padilla
    Abstract:

    Background Septic Thrombophlebitis is an iatrogenic life-threatening disease associated with use of central venous devices and intravenous (IV) therapy. In cancer patients receiving chemotherapy, vein resection or surgical thrombectomy in large central venous lines is time-consuming, can delay administration of chemotherapy, and therefore can compromise tumor control. Experience with thrombolysis has been published for catheter-related thrombosis but for Septic thrombosis, this experience is scarce. Results We describe three patients with cancer and Septic Thrombophlebitis of central veins caused by Staphylococcus aureus treated with catheter removal, thrombolysis, and intravenous (IV) antibiotics. In our reported cases, an initial bolus of 250,000 international units (IU) of streptokinase administered during the first h followed by an infusion of 20,000–40,000 IU/h for 24–36 h through a proximal peripheral vein was sufficient to dissolve the thrombus. After thrombolyisis and parenteral antibiotic for 4–6 weeks the Septic thrombosis due to Staphylococcus aureus solved in all cases. No surgical procedure was needed, and potential placement of a catheter in the same vein was permitted. Conclusion Thrombolysis with streptokinase solved symptoms, cured infection, prevented embolus, and in all cases achieved complete thrombus lysis, avoiding permanent central-vein occlusion.

  • Catheter-related Septic Thrombophlebitis of the great central veins successfully treated with low-dose streptokinase thrombolysis and antimicrobials
    Thrombosis journal, 2005
    Co-Authors: Patricia Volkow, Patricia Cornejo-juárez, Ana Berta Arizpe-bravo, Jorge García-méndez, Enrique Baltazares-lipp, Rogelio Pérez-padilla
    Abstract:

    Background Septic Thrombophlebitis is an iatrogenic life-threatening disease associated with use of central venous devices and intravenous (IV) therapy. In cancer patients receiving chemotherapy, vein resection or surgical thrombectomy in large central venous lines is time-consuming, can delay administration of chemotherapy, and therefore can compromise tumor control. Experience with thrombolysis has been published for catheter-related thrombosis but for Septic thrombosis, this experience is scarce.