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Frank De Vries - One of the best experts on this subject based on the ideXlab platform.

  • Comparability of the age and Sex Distribution of the UK Clinical Practice Research Datalink and the total Dutch population
    Pharmacoepidemiology and drug safety, 2016
    Co-Authors: Roy G.p.j. De Jong, Arlene M. Gallagher, Emily Herrett, Ad Masclee, Maryska L.g. Janssen-heijnen, Frank De Vries
    Abstract:

    Purpose The UK Clinical Practice Research Datalink (CPRD) is increasingly being used by Dutch researchers in epidemiology and pharmacoepidemiology. It is however unclear if the UK CPRD is representative of the Dutch population and whether study results would apply to the Dutch population. Therefore, as first step, our objective was to compare the age and Sex Distribution of the CPRD with the total Dutch population. Methods As a measure of representativeness, the age and Sex Distribution of the UK CPRD were visually and numerically compared with Dutch census data from the StatLine database of the Dutch National Bureau of Statistics in 2011. Results The age Distribution of men and women in the CPRD population was comparable to the Dutch male and female population. Differences of more than 10% only occurred in older age categories (75+ in men and 80+ in women). Conclusions Results from observational studies that have used CPRD data are applicable to the Dutch population, and a useful resource for decision making in the Netherlands. Nevertheless, differences in drug exposure likelihood between countries should be kept in mind, as these could still cause variations in the actual population studied, thereby decreasing its generalizability. Copyright © 2016 John Wiley & Sons, Ltd.

  • [Accepted Manuscript] Comparability of the age and Sex Distribution of the UK Clinical Practice Research Datalink and the total Dutch population.
    2016
    Co-Authors: Roy G.p.j. De Jong, Arlene M. Gallagher, Emily Herrett, Ad Masclee, Maryska L.g. Janssen-heijnen, Frank De Vries
    Abstract:

    : The UK Clinical Practice Research Datalink (CPRD) is increasingly being used by Dutch researchers in epidemiology and pharmacoepidemiology. It is however unclear if the UK CPRD is representative of the Dutch population and whether study results would apply to the Dutch population. Therefore, as first step, our objective was to compare the age and Sex Distribution of the CPRD with the total Dutch population. : As a measure of representativeness, the age and Sex Distribution of the UK CPRD were visually and numerically compared with Dutch census data from the StatLine database of the Dutch National Bureau of Statistics in 2011. : The age Distribution of men and women in the CPRD population was comparable to the Dutch male and female population. Differences of more than 10% only occurred in older age categories (75+ in men and 80+ in women). : Results from observational studies that have used CPRD data are applicable to the Dutch population, and a useful resource for decision making in the Netherlands. Nevertheless, differences in drug exposure likelihood between countries should be kept in mind, as these could still cause variations in the actual population studied, thereby decreasing its generalizability. Copyright © 2016 John Wiley & Sons, Ltd.

Roy G.p.j. De Jong - One of the best experts on this subject based on the ideXlab platform.

  • Comparability of the age and Sex Distribution of the UK Clinical Practice Research Datalink and the total Dutch population
    Pharmacoepidemiology and drug safety, 2016
    Co-Authors: Roy G.p.j. De Jong, Arlene M. Gallagher, Emily Herrett, Ad Masclee, Maryska L.g. Janssen-heijnen, Frank De Vries
    Abstract:

    Purpose The UK Clinical Practice Research Datalink (CPRD) is increasingly being used by Dutch researchers in epidemiology and pharmacoepidemiology. It is however unclear if the UK CPRD is representative of the Dutch population and whether study results would apply to the Dutch population. Therefore, as first step, our objective was to compare the age and Sex Distribution of the CPRD with the total Dutch population. Methods As a measure of representativeness, the age and Sex Distribution of the UK CPRD were visually and numerically compared with Dutch census data from the StatLine database of the Dutch National Bureau of Statistics in 2011. Results The age Distribution of men and women in the CPRD population was comparable to the Dutch male and female population. Differences of more than 10% only occurred in older age categories (75+ in men and 80+ in women). Conclusions Results from observational studies that have used CPRD data are applicable to the Dutch population, and a useful resource for decision making in the Netherlands. Nevertheless, differences in drug exposure likelihood between countries should be kept in mind, as these could still cause variations in the actual population studied, thereby decreasing its generalizability. Copyright © 2016 John Wiley & Sons, Ltd.

  • [Accepted Manuscript] Comparability of the age and Sex Distribution of the UK Clinical Practice Research Datalink and the total Dutch population.
    2016
    Co-Authors: Roy G.p.j. De Jong, Arlene M. Gallagher, Emily Herrett, Ad Masclee, Maryska L.g. Janssen-heijnen, Frank De Vries
    Abstract:

    : The UK Clinical Practice Research Datalink (CPRD) is increasingly being used by Dutch researchers in epidemiology and pharmacoepidemiology. It is however unclear if the UK CPRD is representative of the Dutch population and whether study results would apply to the Dutch population. Therefore, as first step, our objective was to compare the age and Sex Distribution of the CPRD with the total Dutch population. : As a measure of representativeness, the age and Sex Distribution of the UK CPRD were visually and numerically compared with Dutch census data from the StatLine database of the Dutch National Bureau of Statistics in 2011. : The age Distribution of men and women in the CPRD population was comparable to the Dutch male and female population. Differences of more than 10% only occurred in older age categories (75+ in men and 80+ in women). : Results from observational studies that have used CPRD data are applicable to the Dutch population, and a useful resource for decision making in the Netherlands. Nevertheless, differences in drug exposure likelihood between countries should be kept in mind, as these could still cause variations in the actual population studied, thereby decreasing its generalizability. Copyright © 2016 John Wiley & Sons, Ltd.

Hans Helenius - One of the best experts on this subject based on the ideXlab platform.

  • Suicide clustering in a psychiatric hospital with a history of a suicide epidemic: a quantitative study.
    The American journal of psychiatry, 1994
    Co-Authors: Tero Taiminen, Hans Helenius
    Abstract:

    To determine if the suicides in a Finnish psychiatric hospital with a history of a suicide epidemic were clustered and if the Sex Distribution of the suicides followed a random pattern, the authors conducted statistical analyses of the temporal Distribution and Sex Distribution of 59 consecutive inpatient suicides over the years 1967-1992 in the hospital. They found no statistically significant temporal clustering and that the Sex Distribution of the suicides was random. They conclude that inpatient suicide epidemics seem to be rare and separate events, related more to temporary micro-social factors and to the psychopathology of individual patients than to permanent characteristics of a particular hospital. Language: en

Ad Masclee - One of the best experts on this subject based on the ideXlab platform.

  • Comparability of the age and Sex Distribution of the UK Clinical Practice Research Datalink and the total Dutch population
    Pharmacoepidemiology and drug safety, 2016
    Co-Authors: Roy G.p.j. De Jong, Arlene M. Gallagher, Emily Herrett, Ad Masclee, Maryska L.g. Janssen-heijnen, Frank De Vries
    Abstract:

    Purpose The UK Clinical Practice Research Datalink (CPRD) is increasingly being used by Dutch researchers in epidemiology and pharmacoepidemiology. It is however unclear if the UK CPRD is representative of the Dutch population and whether study results would apply to the Dutch population. Therefore, as first step, our objective was to compare the age and Sex Distribution of the CPRD with the total Dutch population. Methods As a measure of representativeness, the age and Sex Distribution of the UK CPRD were visually and numerically compared with Dutch census data from the StatLine database of the Dutch National Bureau of Statistics in 2011. Results The age Distribution of men and women in the CPRD population was comparable to the Dutch male and female population. Differences of more than 10% only occurred in older age categories (75+ in men and 80+ in women). Conclusions Results from observational studies that have used CPRD data are applicable to the Dutch population, and a useful resource for decision making in the Netherlands. Nevertheless, differences in drug exposure likelihood between countries should be kept in mind, as these could still cause variations in the actual population studied, thereby decreasing its generalizability. Copyright © 2016 John Wiley & Sons, Ltd.

  • [Accepted Manuscript] Comparability of the age and Sex Distribution of the UK Clinical Practice Research Datalink and the total Dutch population.
    2016
    Co-Authors: Roy G.p.j. De Jong, Arlene M. Gallagher, Emily Herrett, Ad Masclee, Maryska L.g. Janssen-heijnen, Frank De Vries
    Abstract:

    : The UK Clinical Practice Research Datalink (CPRD) is increasingly being used by Dutch researchers in epidemiology and pharmacoepidemiology. It is however unclear if the UK CPRD is representative of the Dutch population and whether study results would apply to the Dutch population. Therefore, as first step, our objective was to compare the age and Sex Distribution of the CPRD with the total Dutch population. : As a measure of representativeness, the age and Sex Distribution of the UK CPRD were visually and numerically compared with Dutch census data from the StatLine database of the Dutch National Bureau of Statistics in 2011. : The age Distribution of men and women in the CPRD population was comparable to the Dutch male and female population. Differences of more than 10% only occurred in older age categories (75+ in men and 80+ in women). : Results from observational studies that have used CPRD data are applicable to the Dutch population, and a useful resource for decision making in the Netherlands. Nevertheless, differences in drug exposure likelihood between countries should be kept in mind, as these could still cause variations in the actual population studied, thereby decreasing its generalizability. Copyright © 2016 John Wiley & Sons, Ltd.

Maryska L.g. Janssen-heijnen - One of the best experts on this subject based on the ideXlab platform.

  • Comparability of the age and Sex Distribution of the UK Clinical Practice Research Datalink and the total Dutch population
    Pharmacoepidemiology and drug safety, 2016
    Co-Authors: Roy G.p.j. De Jong, Arlene M. Gallagher, Emily Herrett, Ad Masclee, Maryska L.g. Janssen-heijnen, Frank De Vries
    Abstract:

    Purpose The UK Clinical Practice Research Datalink (CPRD) is increasingly being used by Dutch researchers in epidemiology and pharmacoepidemiology. It is however unclear if the UK CPRD is representative of the Dutch population and whether study results would apply to the Dutch population. Therefore, as first step, our objective was to compare the age and Sex Distribution of the CPRD with the total Dutch population. Methods As a measure of representativeness, the age and Sex Distribution of the UK CPRD were visually and numerically compared with Dutch census data from the StatLine database of the Dutch National Bureau of Statistics in 2011. Results The age Distribution of men and women in the CPRD population was comparable to the Dutch male and female population. Differences of more than 10% only occurred in older age categories (75+ in men and 80+ in women). Conclusions Results from observational studies that have used CPRD data are applicable to the Dutch population, and a useful resource for decision making in the Netherlands. Nevertheless, differences in drug exposure likelihood between countries should be kept in mind, as these could still cause variations in the actual population studied, thereby decreasing its generalizability. Copyright © 2016 John Wiley & Sons, Ltd.

  • [Accepted Manuscript] Comparability of the age and Sex Distribution of the UK Clinical Practice Research Datalink and the total Dutch population.
    2016
    Co-Authors: Roy G.p.j. De Jong, Arlene M. Gallagher, Emily Herrett, Ad Masclee, Maryska L.g. Janssen-heijnen, Frank De Vries
    Abstract:

    : The UK Clinical Practice Research Datalink (CPRD) is increasingly being used by Dutch researchers in epidemiology and pharmacoepidemiology. It is however unclear if the UK CPRD is representative of the Dutch population and whether study results would apply to the Dutch population. Therefore, as first step, our objective was to compare the age and Sex Distribution of the CPRD with the total Dutch population. : As a measure of representativeness, the age and Sex Distribution of the UK CPRD were visually and numerically compared with Dutch census data from the StatLine database of the Dutch National Bureau of Statistics in 2011. : The age Distribution of men and women in the CPRD population was comparable to the Dutch male and female population. Differences of more than 10% only occurred in older age categories (75+ in men and 80+ in women). : Results from observational studies that have used CPRD data are applicable to the Dutch population, and a useful resource for decision making in the Netherlands. Nevertheless, differences in drug exposure likelihood between countries should be kept in mind, as these could still cause variations in the actual population studied, thereby decreasing its generalizability. Copyright © 2016 John Wiley & Sons, Ltd.