The Experts below are selected from a list of 297 Experts worldwide ranked by ideXlab platform
Armin Börner - One of the best experts on this subject based on the ideXlab platform.
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a new target for highly stereoselective katsuki Sharpless Epoxidation one pot synthesis of c2 symmetric 2 2 bioxiranes
European Journal of Organic Chemistry, 2007Co-Authors: Vitaliy A. Bilenko, Haijun Jiao, Anke Spannenberg, Christine Fischer, Helmut Reinke, Jutta Kösters, Igor V. Komarov, Armin BörnerAbstract:The double asymmetric Katsuki–Sharpless Epoxidation of a conjugated diallyl alcohol affords excellent enantioselectivity (>97 % ee), the product being isolated as the stable p-nitrobenzoate 5a or tosylate 5b. The optical purities of the chiral epoxides were determined by HPLC on chiral columns, while the molecular structures of compounds 5a and 7 and the absolute configuration of mono-epoxide 12 were confirmed by X-ray crystallography. Possible π–π stacking interaction has been evaluated by ab initio calculation.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
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A New Target for Highly Stereoselective Katsuki–Sharpless Epoxidation – One‐Pot Synthesis of C2‐Symmetric 2,2′‐Bioxiranes
European Journal of Organic Chemistry, 2007Co-Authors: Vitaliy A. Bilenko, Haijun Jiao, Anke Spannenberg, Christine Fischer, Helmut Reinke, Jutta Kösters, Igor V. Komarov, Armin BörnerAbstract:The double asymmetric Katsuki–Sharpless Epoxidation of a conjugated diallyl alcohol affords excellent enantioselectivity (>97 % ee), the product being isolated as the stable p-nitrobenzoate 5a or tosylate 5b. The optical purities of the chiral epoxides were determined by HPLC on chiral columns, while the molecular structures of compounds 5a and 7 and the absolute configuration of mono-epoxide 12 were confirmed by X-ray crystallography. Possible π–π stacking interaction has been evaluated by ab initio calculation.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Palakodety Radha Krishna - One of the best experts on this subject based on the ideXlab platform.
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total synthesis of proposed structure of polyporolide via acid catalyzed lactonization
Tetrahedron Letters, 2015Co-Authors: Ramesh Kunde, Palakodety Radha KrishnaAbstract:Abstract Herein, we report the total synthesis of proposed structure of polyporolide 1 via Barbier allylation, Sharpless Epoxidation, Titanium(IV) promoted regioselective ring-opening reaction of epoxy homoallyl alcohol and acid catalyzed intramolecular lactonization as the key steps. Also a chiron approach was adopted for the same in greater overall yields.
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regioselective nucleophilic ring opening reaction of chiral epoxyallyl alcohols a ready access to the pyran core of macrolactin 3
ChemInform, 2014Co-Authors: Palakodety Radha Krishna, Rajesh Nomula, Kallaganti Rama V S KrishnaAbstract:The synthesis of the pyran core (VI) of macrolactin 3 is based on Sharpless Epoxidation, Ti(IV)-promoted nucleophilic regioselective epoxide ring-opening, and oxa-Michael addition as the key steps.
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regioselective nucleophilic ring opening reaction of chiral epoxyallyl alcohols a ready access to the pyran core of macrolactin 3
Tetrahedron Letters, 2014Co-Authors: Palakodety Radha Krishna, Rajesh Nomula, Kallaganti Rama V S KrishnaAbstract:Herein we report the synthetic strategy towards the pyran core of macrolactin 3 via Sharpless Epoxidation, titanium(IV) mediated regioselective ring-opening reaction of epoxyallyl alcohol/epoxy alcohol and oxa-Michael addition as the key steps.
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Total synthesis of the 2,6-disubstituted piperidine alkaloid (−)-andrachcinidine
Tetrahedron-asymmetry, 2013Co-Authors: Palakodety Radha Krishna, Bonepally Karunakar ReddyAbstract:Abstract The total synthesis of the 2,6-disubstituted piperidine alkaloid (−)-andrachcinidine is reported using Keck’s asymmetric allylation, Sharpless Epoxidation, nucleophilic substitution, and intramolecular aza-Michael addition as the key steps.
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total synthesis of the 2 6 disubstituted piperidine alkaloid andrachcinidine
Tetrahedron-asymmetry, 2013Co-Authors: Palakodety Radha Krishna, Bonepally Karunakar ReddyAbstract:Abstract The total synthesis of the 2,6-disubstituted piperidine alkaloid (−)-andrachcinidine is reported using Keck’s asymmetric allylation, Sharpless Epoxidation, nucleophilic substitution, and intramolecular aza-Michael addition as the key steps.
Vitaliy A. Bilenko - One of the best experts on this subject based on the ideXlab platform.
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a new target for highly stereoselective katsuki Sharpless Epoxidation one pot synthesis of c2 symmetric 2 2 bioxiranes
European Journal of Organic Chemistry, 2007Co-Authors: Vitaliy A. Bilenko, Haijun Jiao, Anke Spannenberg, Christine Fischer, Helmut Reinke, Jutta Kösters, Igor V. Komarov, Armin BörnerAbstract:The double asymmetric Katsuki–Sharpless Epoxidation of a conjugated diallyl alcohol affords excellent enantioselectivity (>97 % ee), the product being isolated as the stable p-nitrobenzoate 5a or tosylate 5b. The optical purities of the chiral epoxides were determined by HPLC on chiral columns, while the molecular structures of compounds 5a and 7 and the absolute configuration of mono-epoxide 12 were confirmed by X-ray crystallography. Possible π–π stacking interaction has been evaluated by ab initio calculation.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
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A New Target for Highly Stereoselective Katsuki–Sharpless Epoxidation – One‐Pot Synthesis of C2‐Symmetric 2,2′‐Bioxiranes
European Journal of Organic Chemistry, 2007Co-Authors: Vitaliy A. Bilenko, Haijun Jiao, Anke Spannenberg, Christine Fischer, Helmut Reinke, Jutta Kösters, Igor V. Komarov, Armin BörnerAbstract:The double asymmetric Katsuki–Sharpless Epoxidation of a conjugated diallyl alcohol affords excellent enantioselectivity (>97 % ee), the product being isolated as the stable p-nitrobenzoate 5a or tosylate 5b. The optical purities of the chiral epoxides were determined by HPLC on chiral columns, while the molecular structures of compounds 5a and 7 and the absolute configuration of mono-epoxide 12 were confirmed by X-ray crystallography. Possible π–π stacking interaction has been evaluated by ab initio calculation.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Harshadas M. Meshram - One of the best experts on this subject based on the ideXlab platform.
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Concise Stereoselective Total Synthesis of (+)-Mueggelone.
ChemInform, 2013Co-Authors: Dachepally Aravind Kumar, Harshadas M. MeshramAbstract:(+)-Mueggelone (I) is synthesized from commercially available and inexpensive starting materials via Sharpless Epoxidation, Jacobsen resolution, lactonization and cross metathesis.
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Stereoselective Total Synthesis of Multiplolide A and of a Diastereoisomer
Helvetica Chimica Acta, 2013Co-Authors: Bandi Chennakesava Reddy, Palakuri Ramesh, Vikas M. Bangade, Harshadas M. MeshramAbstract:A stereoselective total synthesis of multiplolide A (1) and of its diastereoisomer 2 was described from easily accessible starting materials (Schemes 2–4). The synthetic strategy involves a Jacobsen resolution, Sharpless Epoxidation, Swern oxidation, Yamaguchi reaction, and ring-closing metathesis (RCM).
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First stereoselective total synthesis of Phomolide G and H via RCM protocol
Tetrahedron Letters, 2012Co-Authors: Palakuri Ramesh, B. Chennakesava Reddy, Harshadas M. MeshramAbstract:Abstract A first total synthetic route has been reported for the synthesis of Phomolide G and H. The syntheses of fragments were initiated from commercially available and inexpensive starting material ( R )-epichlorohydrin. The synthesis involves a key Sharpless Epoxidation, stereoselective epoxide opening, lactonization and ring closing metathesis (RCM).
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Total Synthesis of Nonenolide
Helvetica Chimica Acta, 2010Co-Authors: Harshadas M. Meshram, Dachepally Aravind Kumar, Palakuri RameshAbstract:A novel synthetic route has been reported for the synthesis of nonenolide. The syntheses of fragments were initiated from commercially available and inexpensive starting materials. The synthesis involves key steps like Sharpless Epoxidation, Jacobsen's resolution, lactonization, and cross-metathesis.
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A concise stereoselective total synthesis of Botryolide B
Tetrahedron Letters, 2010Co-Authors: B. Chennakesava Reddy, Harshadas M. MeshramAbstract:The first total synthesis of Botryolide B is described from easily accessible starting materials. The synthetic strategy involves Jacobsen resolution, Sharpless Epoxidation, Swern oxidation, Yamaguchi reaction, and ring closing metathesis (RCM).
John G. Cumming - One of the best experts on this subject based on the ideXlab platform.
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a stereocontrolled synthesis of a c19 c32 c17 c30 segment for swinholide a and misakinolide a cytotoxic dimeric macrolides from theonella swinhoei
Tetrahedron Letters, 1992Co-Authors: John G. CummingAbstract:The C19-C32/C17-C30 segment (-)-5 of swinholide A / misakinolide A was prepared in 15 steps (6% yield) from (±)-13. Key steps include the Sharpless Epoxidation, 13 → 14, the acetal allylation, 12 → 16, the anti aldol, 17 + 11 → 9, and the alkene hydroboration, 19 → 20.
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A stereocontrolled synthesis of a C19-C32 / C17-C30 Segment for swinholide A and misakinolide A, Cytotoxic dimeric macrolides from theonella swinhoei.
Tetrahedron Letters, 1992Co-Authors: John G. CummingAbstract:The C19-C32/C17-C30 segment (-)-5 of swinholide A / misakinolide A was prepared in 15 steps (6% yield) from (±)-13. Key steps include the Sharpless Epoxidation, 13 → 14, the acetal allylation, 12 → 16, the anti aldol, 17 + 11 → 9, and the alkene hydroboration, 19 → 20.