The Experts below are selected from a list of 15258 Experts worldwide ranked by ideXlab platform
Michael J Dover - One of the best experts on this subject based on the ideXlab platform.
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a population genomics analysis of the native irish galway Sheep Breed
Frontiers in Genetics, 2019Co-Authors: Gillian P Mchugo, Samuel S Browett, I A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen David Edward Park, David A Magee, Erik Scraggs, Michael J DoverAbstract:The Galway Sheep population is the only native Irish Sheep Breed and this livestock genetic resource is currently categorised as ‘at-risk’. In the present study, comparative population genomics analyses of Galway Sheep and other Sheep populations of European origin were used to investigate the microevolution and recent genetic history of the Breed. These analyses support the hypothesis that British Leicester Sheep were used in the formation of the Galway. When compared to conventional and endangered Breeds, the Galway Breed was intermediate in effective population size, genomic inBreeding and runs of homozygosity. This indicates that, although the Galway Breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway Breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other Breeds, which highlighted candidate genes that may be involved in production and health traits.
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a population genomics analysis of the native irish galway Sheep Breed
bioRxiv, 2019Co-Authors: Gillian P Mchugo, Samuel S Browett, I A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen David Edward Park, David A Magee, Erik Scraggs, Michael J DoverAbstract:The Galway Sheep population is the only native Irish Sheep Breed and represents an important livestock genetic resource, which is currently categorised as "at-risk". In the present study, comparative population genomics analyses of Galway Sheep and other Sheep populations of European origin were used to investigate the microevolution and recent genetic history of the Breed. These analyses support the hypothesis that British Leicester Sheep were used in the formation of the Galway Breed and suggest more recent gene flow from the Suffolk Sheep Breed. When compared to conventional and endangered Breeds, the Galway Breed was intermediate in effective population size, genomic inBreeding and runs of homozygosity. This indicates that, although the Galway Breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway Breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other Breeds, which highlighted candidate genes that may be involved in meat and wool production.
Gillian P Mchugo - One of the best experts on this subject based on the ideXlab platform.
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a population genomics analysis of the native irish galway Sheep Breed
Frontiers in Genetics, 2019Co-Authors: Gillian P Mchugo, Samuel S Browett, I A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen David Edward Park, David A Magee, Erik Scraggs, Michael J DoverAbstract:The Galway Sheep population is the only native Irish Sheep Breed and this livestock genetic resource is currently categorised as ‘at-risk’. In the present study, comparative population genomics analyses of Galway Sheep and other Sheep populations of European origin were used to investigate the microevolution and recent genetic history of the Breed. These analyses support the hypothesis that British Leicester Sheep were used in the formation of the Galway. When compared to conventional and endangered Breeds, the Galway Breed was intermediate in effective population size, genomic inBreeding and runs of homozygosity. This indicates that, although the Galway Breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway Breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other Breeds, which highlighted candidate genes that may be involved in production and health traits.
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a population genomics analysis of the native irish galway Sheep Breed
bioRxiv, 2019Co-Authors: Gillian P Mchugo, Samuel S Browett, I A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen David Edward Park, David A Magee, Erik Scraggs, Michael J DoverAbstract:The Galway Sheep population is the only native Irish Sheep Breed and represents an important livestock genetic resource, which is currently categorised as "at-risk". In the present study, comparative population genomics analyses of Galway Sheep and other Sheep populations of European origin were used to investigate the microevolution and recent genetic history of the Breed. These analyses support the hypothesis that British Leicester Sheep were used in the formation of the Galway Breed and suggest more recent gene flow from the Suffolk Sheep Breed. When compared to conventional and endangered Breeds, the Galway Breed was intermediate in effective population size, genomic inBreeding and runs of homozygosity. This indicates that, although the Galway Breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway Breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other Breeds, which highlighted candidate genes that may be involved in meat and wool production.
E Manfredi - One of the best experts on this subject based on the ideXlab platform.
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genomic selection in the french lacaune dairy Sheep Breed
Journal of Dairy Science, 2012Co-Authors: S I Duchemin, Francis Barillet, G Baloche, J M Astruc, Andres Legarra, H Larroque, Christele Robertgranie, Carine Colombani, E ManfrediAbstract:Genomic selection aims to increase accuracy and to decrease generation intervals, thus increasing genetic gains in animal Breeding. Using real data of the French Lacaune dairy Sheep Breed, the purpose of this study was to compare the observed accuracies of genomic estimated Breeding values using different models (infinitesimal only, markers only, and joint estimation of infinitesimal and marker effects) and methods [BLUP, Bayes Cπ, partial least squares (PLS), and sparse PLS]. The training data set included results of progeny tests of 1,886 rams born from 1998 to 2006, whereas the validation set had results of 681 rams born in 2007 and 2008. The 3 lactation traits studied (milk yield, fat content, and somatic cell scores) had heritabilities varying from 0.14 to 0.41. The inclusion of molecular information, as compared with traditional schemes, increased accuracies of estimated Breeding values of young males at birth from 18 up to 25%, according to the trait. Accuracies of genomic methods varied from 0.4 to 0.6, according to the traits, with minor differences among genomic approaches. In Bayes Cπ, the joint estimation of marker and infinitesimal effects had a slightly favorable effect on the accuracies of genomic estimated Breeding values, and were especially beneficial for somatic cell counts, the less heritable trait. Inclusion of infinitesimal effects also improved slopes of predictive regression equations. Methods that select markers implicitly (Bayes Cπ and sparse PLS) were advantageous for some models and traits, and are of interest for further quantitative trait loci studies.
David A Magee - One of the best experts on this subject based on the ideXlab platform.
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a population genomics analysis of the native irish galway Sheep Breed
Frontiers in Genetics, 2019Co-Authors: Gillian P Mchugo, Samuel S Browett, I A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen David Edward Park, David A Magee, Erik Scraggs, Michael J DoverAbstract:The Galway Sheep population is the only native Irish Sheep Breed and this livestock genetic resource is currently categorised as ‘at-risk’. In the present study, comparative population genomics analyses of Galway Sheep and other Sheep populations of European origin were used to investigate the microevolution and recent genetic history of the Breed. These analyses support the hypothesis that British Leicester Sheep were used in the formation of the Galway. When compared to conventional and endangered Breeds, the Galway Breed was intermediate in effective population size, genomic inBreeding and runs of homozygosity. This indicates that, although the Galway Breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway Breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other Breeds, which highlighted candidate genes that may be involved in production and health traits.
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a population genomics analysis of the native irish galway Sheep Breed
bioRxiv, 2019Co-Authors: Gillian P Mchugo, Samuel S Browett, I A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen David Edward Park, David A Magee, Erik Scraggs, Michael J DoverAbstract:The Galway Sheep population is the only native Irish Sheep Breed and represents an important livestock genetic resource, which is currently categorised as "at-risk". In the present study, comparative population genomics analyses of Galway Sheep and other Sheep populations of European origin were used to investigate the microevolution and recent genetic history of the Breed. These analyses support the hypothesis that British Leicester Sheep were used in the formation of the Galway Breed and suggest more recent gene flow from the Suffolk Sheep Breed. When compared to conventional and endangered Breeds, the Galway Breed was intermediate in effective population size, genomic inBreeding and runs of homozygosity. This indicates that, although the Galway Breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway Breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other Breeds, which highlighted candidate genes that may be involved in meat and wool production.
Erik Scraggs - One of the best experts on this subject based on the ideXlab platform.
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a population genomics analysis of the native irish galway Sheep Breed
Frontiers in Genetics, 2019Co-Authors: Gillian P Mchugo, Samuel S Browett, I A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen David Edward Park, David A Magee, Erik Scraggs, Michael J DoverAbstract:The Galway Sheep population is the only native Irish Sheep Breed and this livestock genetic resource is currently categorised as ‘at-risk’. In the present study, comparative population genomics analyses of Galway Sheep and other Sheep populations of European origin were used to investigate the microevolution and recent genetic history of the Breed. These analyses support the hypothesis that British Leicester Sheep were used in the formation of the Galway. When compared to conventional and endangered Breeds, the Galway Breed was intermediate in effective population size, genomic inBreeding and runs of homozygosity. This indicates that, although the Galway Breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway Breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other Breeds, which highlighted candidate genes that may be involved in production and health traits.
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a population genomics analysis of the native irish galway Sheep Breed
bioRxiv, 2019Co-Authors: Gillian P Mchugo, Samuel S Browett, I A S Randhawa, Dawn J Howard, Michael P Mullen, Ian W Richardson, Stephen David Edward Park, David A Magee, Erik Scraggs, Michael J DoverAbstract:The Galway Sheep population is the only native Irish Sheep Breed and represents an important livestock genetic resource, which is currently categorised as "at-risk". In the present study, comparative population genomics analyses of Galway Sheep and other Sheep populations of European origin were used to investigate the microevolution and recent genetic history of the Breed. These analyses support the hypothesis that British Leicester Sheep were used in the formation of the Galway Breed and suggest more recent gene flow from the Suffolk Sheep Breed. When compared to conventional and endangered Breeds, the Galway Breed was intermediate in effective population size, genomic inBreeding and runs of homozygosity. This indicates that, although the Galway Breed is declining, it is still relatively genetically diverse and that conservation and management plans informed by genomic information may aid its recovery. The Galway Breed also exhibited distinct genomic signatures of artificial or natural selection when compared to other Breeds, which highlighted candidate genes that may be involved in meat and wool production.