The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Elena M Lopezmartin - One of the best experts on this subject based on the ideXlab platform.
-
validation of potential effects on human health of in vivo experimental models studied in rats exposed to sub thermal radiofrequency possible health risks due to the interaction of electromagnetic pollution and environmental particles
IEEE Access, 2019Co-Authors: Aaron A Salassanchez, Alberto Lopezfurelos, Antonio J Rodriguezgonzalez, F Arespena, Elena M LopezmartinAbstract:Studies are based on the exposure of Sprague-Dawley rats (250 male and 250 female rats) to electromagnetic fields (EMF) at different frequencies in standing and travelling wave chambers. Values of specific absortion rate (SAR) for all of these experiments were obtained from commercially available FDTD-based simulation software based on numerical phantom animals. An experimental radiation system was developed with a standing-wave cavity which keeps electromagnetic parameters constant while facilitating stress-free exposure of animals to non-thermal radiation. This makes it possible to directly measure the power absorbed by the animal and determine whole-body mean SAR according to weight. All studies using this setup were performed with global system for mobile communication (GSM) radiation at 900 MHz. The simple picrotoxin model made allow to identify morphological signs of neurotoxicity in rat brain tissue. Experiments involving travelling waves were done in a commercial Gigahertz Transverse ElectroMagnetic (GTEM) chamber connected to one or two vector Signal Generators (to carry single or multiple EMF exposure frequencies). In the diathermy model, rat thyroid and thymus exposed to 2.45 GHz radiation showed visible morphological and immune effects. Cellular stress in the cerebral cortex, the cerebellum or both seems to be more associated with the type of Signal than with additive effects of combined frequencies. Finally, some hypothesis related with the future models about the ElectroMagnetic (EM) pollution are established. In an urban environmental that combines the electromagnetic and chemical pollution of environmental particles, cortical excitability, inflammatory response, and cell injury can be modified.
Libing Wang - One of the best experts on this subject based on the ideXlab platform.
-
femtogram ultrasensitive aptasensor for the detection of ochratoxina
Biosensors and Bioelectronics, 2013Co-Authors: Honghong Yin, Hua Kuang, Libing WangAbstract:A simple and ultrasensitive method was developed for the detection of Ochratoxin A, utilizing an aptamer as a molecular recognition probe and real-time quantitative PCR (RT-qPCR) amplification of its complementary DNA as Signal Generators. Under the optimized conditions, the cycle threshold (Ct) increased linearly with 10-fold serial dilutions of Ochratoxin A (OTA) from 5×10⁻⁶ to 5 ng mL⁻¹, with a limit of detection (LOD) of 1 fg mL⁻¹. The specificity of this aptasensor was considered to be excellent, as when tested against four other toxins it produced no obvious Ct value change. Furthermore, a satisfactory analyte concentration recovery was obtained from a series of concentrations of OTA spiked into red wine. Therefore, this highly sensitive approach shows a significant potential in a wide range of target analytes.
J Verd - One of the best experts on this subject based on the ideXlab platform.
-
nonlinear cc beam microresonator model for system level electrical simulations application to bistable behavior analysis
Sensors and Actuators A-physical, 2018Co-Authors: Joan Barcelo, S A Bota, Jaume Segura, J VerdAbstract:Abstract Microelectromechanical resonators nonlinearities can be exploited in many ways to obtain a set of diverse new applications. In particular, some applications of bistable behavior includes threshold mechanical switches, memory cells, energy harvesting and chaotic Signal Generators. A key step for practical and efficient design for bistability behavior involves accounting for accurate and efficient models. In this paper we present a nonlinear electromechanical model for capacitive clamped-clamped beam resonators implemented in an analog hardware description language (AHDL) enabling system level electrical simulations. The model accounts for nonlinearities from variable resonator-electrode gap, residual fabrication stress, fringing field contributions as well as an accurate resonator deflection profile in contrast to parallel plate approximations. The model has been applied to derive for first time accurate analytical expressions for bistability design conditions. The work includes FEM analysis and experimental data that corroborates the correctness of the model in describing the required bias voltage conditions for bistability.
-
electrostatically actuated microbeam resonators as chaotic Signal Generators a practical perspective
Communications in Nonlinear Science and Numerical Simulation, 2016Co-Authors: Joan Barcelo, J L Rossello, S Bota, J Segura, J VerdAbstract:Abstract The biasing requirements to obtain cross-well chaotic motion for in-plane electrostatically driven beam-shaped MEMS (micro-electromechanical systems) resonators are investigated for typical actuation/readout topologies. Practical applications such as Signal chaotic Generators require reasonable and wide enough range voltages (dc and ac) to assure a feasible control in current CMOS or nanotechnologies. We found that these conditions are only obtained when enabling cross-well motion operation instead of in-well operation. Moreover, in contrast to many works that take unfeasible design parameters, we provide for the first time the design rules and biasing ranges required for commercial CMOS technologies and nanotechnology when considering typical parameter values from various fabrication approaches.
Zhiqiang Gao - One of the best experts on this subject based on the ideXlab platform.
-
gold nanoparticle enabled real time ligation chain reaction for ultrasensitive detection of dna
Journal of the American Chemical Society, 2012Co-Authors: Wei Shen, Huimin Deng, Zhiqiang GaoAbstract:A simple and ultrasensitive colorimetric DNA assay based on the detection of the product of a ligation chain reaction (LCR) and the use of gold nanoparticles (AuNPs) as Signal Generators has been developed. During LCR, the AuNPs were ligated together, resulting in a distinct color change in real time after a sufficient number of thermal cycles. The cumulative nature of the protocol produced a detection limit of 20 aM with a selectivity factor of 10(3).
Alessandro Astolfi - One of the best experts on this subject based on the ideXlab platform.
-
model reduction by matching the steady state response of explicit Signal Generators
IEEE Transactions on Automatic Control, 2016Co-Authors: Giordano Scarciotti, Alessandro AstolfiAbstract:Model reduction by moment matching for “interpolation Signals” which do not have an implicit model, i.e., they do not satisfy a differential equation, is considered. Particular attention is devoted to discontinuous, possibly periodic, Signals. The notion of moment is reformulated using an integral matrix equation. It is shown that, under specific conditions, the new definition and the one based on the Sylvester equation are equivalent. New parameterized families of models achieving moment matching are given. The results are illustrated by means of a numerical example.
-
characterization of the moments of a linear system driven by explicit Signal Generators
Advances in Computing and Communications, 2015Co-Authors: Giordano Scarciotti, Alessandro AstolfiAbstract:The characterization of the moments of a linear system for “interpolation Signals” which do not have an implicit model, i.e. they do not satisfy a differential equation, is considered. Particular attention is devoted to discontinuous, possibly periodic, Signals. The notion of moment is reformulated using an integral matrix equation and it is shown that, under specific conditions, the new definition and the one based on the Sylvester equation are equivalent. The results, illustrated by mean of two numerical examples, lay the foundation for the characterization of reduced order models for such a class of input.