Travelling Wave

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Kevin Giles - One of the best experts on this subject based on the ideXlab platform.

  • Travelling Wave ion mobility
    International Journal for Ion Mobility Spectrometry, 2013
    Co-Authors: Kevin Giles
    Abstract:

    The research papers in this issue of the International Journal for Ion Mobility Spectrometry are the concluding articles of a two-part special issue on Travelling Wave Ion Mobility. The first issue, published in March (Volume 16, Issue 1, March 2013), covered a wide range of research areas: ‘Resolving the microcosmos of complex samples: UPLC/Travelling Wave ion mobility separation high resolution mass spectrometry for the analysis of in vivo drug metabolism studies’ by Blech and Laux; ‘The effects of cation adduction upon the conformation of three-helix bundle protein domains’ by Sokratous et al.; ‘Monitoring oligomer formation from self-aggregating amylin peptides using ESI-IMS-MS’ by Young et al.; ‘Traveling-Wave ion mobility-mass spectrometry reveals additional mechanistic details in the stabilization of protein complex ions through tuned salt additives’ by Han and Ruotolo; 'Coupling electrospray corona discharge, charge reduction and ion mobility mass spectrometry: From peptides to large macromolecular protein complexes' by Campuzano and Schnier; and 'Structural studies of metal ligand complexes by ion mobility-mass spectrometry' by Wright et al. The papers in this issue extend upon the range of studies presented in the first issue and together they illustrate the broad utility and applicability of (Travelling Wave) ion mobility—mass spectrometry. Since the launch of the first Travelling Wave ion mobility system (SYNAPT) some 7 years ago, the interest in ion mobility coupled with mass spectrometry has grown tremendously and shows no sign of abating. We continue to push the boundaries of ion mobility instrumentation design and, together with our customers and collaborators, work to extend the applications of this technology. I am indebted to the small cross-section of our customers/collaborators who have taken the time to contribute to this special issue on Travelling Wave Ion Mobility and offer my sincere thanks.

  • enhancements in Travelling Wave ion mobility resolution
    Rapid Communications in Mass Spectrometry, 2011
    Co-Authors: Kevin Giles, Jonathan P Williams, Iain Campuzano
    Abstract:

    The use of ion mobility separation to determine the collision cross-section of a gas-phase ion can provide valuable structural information. The introduction of Travelling-Wave ion mobility within a quadrupole/time-of-flight mass spectrometer has afforded routine collision cross-section measurements to be performed on a range of ionic species differing in gas-phase size/structure and molecular weight at physiologically relevant concentrations. Herein we discuss the technical advances in the second-generation Travelling-Wave ion mobility separator, which result in up to a four-fold increase in mobility resolution. This improvement is demonstrated using two reverse peptides (mw 490 Da), small ruthenium-containing anticancer drugs (mw 427 Da), a cisplatin-modified protein (mw 8776 Da) and the noncovalent tetradecameric chaperone complex GroEL (mw 802 kDa). What is also shown are that the collision cross-sections determined using the second-generation mobility separator correlate well with the previous generation and theoretically derived values. Copyright © 2011 John Wiley & Sons, Ltd.

Iain Campuzano - One of the best experts on this subject based on the ideXlab platform.

  • enhancements in Travelling Wave ion mobility resolution
    Rapid Communications in Mass Spectrometry, 2011
    Co-Authors: Kevin Giles, Jonathan P Williams, Iain Campuzano
    Abstract:

    The use of ion mobility separation to determine the collision cross-section of a gas-phase ion can provide valuable structural information. The introduction of Travelling-Wave ion mobility within a quadrupole/time-of-flight mass spectrometer has afforded routine collision cross-section measurements to be performed on a range of ionic species differing in gas-phase size/structure and molecular weight at physiologically relevant concentrations. Herein we discuss the technical advances in the second-generation Travelling-Wave ion mobility separator, which result in up to a four-fold increase in mobility resolution. This improvement is demonstrated using two reverse peptides (mw 490 Da), small ruthenium-containing anticancer drugs (mw 427 Da), a cisplatin-modified protein (mw 8776 Da) and the noncovalent tetradecameric chaperone complex GroEL (mw 802 kDa). What is also shown are that the collision cross-sections determined using the second-generation mobility separator correlate well with the previous generation and theoretically derived values. Copyright © 2011 John Wiley & Sons, Ltd.

John E Bowers - One of the best experts on this subject based on the ideXlab platform.

Qin Jian - One of the best experts on this subject based on the ideXlab platform.

  • STUDY ON SINGLE TERMINAL Travelling Wave FAULT LOCATION OF TRANSMISSION LINE
    Power system technology, 2005
    Co-Authors: Qin Jian
    Abstract:

    The main factors influencing single-terminal Travelling Wave fault location precision, including the generatrix structure, grounding resistance, T type line structure and fault position, are analyzed. The author points out that the most important features of Travelling Wave are its polarity and amplitude, and proposes a comprehensive method to judge Travelling Wave polarity in which current Travelling Wave polarity and voltage Travelling Wave polarity are considered. It is easy for this method to identify whether the Travelling Wave is reflect or refract Travelling Wave from the line itself or that from other lines, and comparing with other methods the reliability of the judgment can be greatly improved. It is also pointed out that the single terminal Travelling Wave fault location method is not suitable under certain line structure and fault conditions, besides there is dead zone in single terminal Travelling Wave fault location method. To implement reliable fault location by single terminal fault location method, it is necessary to conduct combined single terminal fault location in company with impedance method; when single terminal Travelling Wave fault location method is failed, the fault location result from impedance method must be used as the supplement of the former to make up the insufficient of both above-mentioned fault location methods and realize the accurate fault location.

Zheng Jian - One of the best experts on this subject based on the ideXlab platform.

  • FIELD SHORT-CIRCUIT TEST TO VALIDATE Travelling Wave FAULT LOCATION USING WaveLET TRANSFORM
    Power system technology, 2001
    Co-Authors: Zheng Jian
    Abstract:

    Existing methods for Travelling Wave fault location seldom consider the attenuation and distortion of Travelling Wave propagating in transmission line and do not solve the problems to define the arrival time of Travelling Wave and the propagation velocity properly, which leads to poor location accuracy. For this reason a new double terminal Travelling Wave method using Wavelet transform (WT) is presented. A field short circuit test has been performed to validate the applicability and accuracy of the new method. This paper describes the field test and the analysis results of the test data, meanwhile a comparison between WT method and traditional method is given. The field test results show that the accuracy of WT method is higher than that of traditional method and not affected by many factors, such as fault occurring voltage angle. The new method is capable of locating faults on transmission lines with accuracy up to ± 300 meters. WT is suitable for Travelling Wave fault location.