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Johan Ormel - One of the best experts on this subject based on the ideXlab platform.
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occurrence recognition and outcome of psychological disorders in primary care
American Journal of Psychiatry, 1996Co-Authors: B G Tiemens, Johan Ormel, Gregory E SimonAbstract:OBJECTIVE: The authors' goal was to cross-validate the earlier finding of the Groningen Primary Care Study that recognition of psychological disorders was associated with better patient outcomes. METHOD: The 12-item General Health Questionnaire was used to screen 1,271 consecutive primary care patients. A stratified sample of 340 of these patients participated in the second-stage baseline series of interviews, which included the Composite International Diagnostic Interview, the occupational role section of the Social Disability Schedule, the 28-item General Health Questionnaire, and the SCL-90. Three months later 209 of the patients completed the 28-item General Health Questionnaire and the SCL-90, and 12 months later 213 of the patients completed the second-stage baseline series of interviews. The study was carried out in six primary care practices (11 general practitioners) in the northern part of The Netherlands. RESULTS: Recognition of psychological disorders was associated with higher initial severity of psychopathology and occupational Disability and with a psychological reason for the medical encounter. Recognition rates were higher for anxiety than for depression. Patients whose psychological disorders were recognized did not have better outcomes than those whose psychological disorders were not recognized. CONCLUSIONS: Recognition of psychological disorders was not associated with better outcome. Recognition is a necessary but not a sufficient condition for delivery of treatment according to clinical guidelines. Increasing recognition is likely to improve outcomes only if general practitioners have the skills and resources to deliver adequate interventions.
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self report Disability in an international primary care study of psychological illness
Journal of Clinical Epidemiology, 1996Co-Authors: M Von Korff, Johan Ormel, Bedirhan T Ustun, Incila Kaplan, Gregory E SimonAbstract:We assessed the replicability of reliability and validity of a brief self-report Disability scale, adapted from the Medical Outcomes Survey (short form), in a 15-center, cross-national, multilingual study of psychological illness among primary care patients (n = 5438). Across all 15 centers in the World Health Organization Collaborative Study of Psychological Problems in General Health Care, the reliability of the Disability scale was high and individual items were responsive at similar levels of Disability. Self-report Disability was consistently correlated with Disability in work role (including housework) as rated by interviewers according to the Groningen Social Disability Schedule, a semistructured method taking local norms into account. Disability as measured by the self-report questionnaire was also consistently correlated with depressive symptoms as measured by the General Health Questionnaire. At each center, the Disability items formed a moderately to strongly hierarchical (Guttman-like) scale. These findings support the feasibility of using self-report Disability scales in cross-national primary care research.
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depression anxiety and Social Disability show synchrony of change in primary care patients
American Journal of Public Health, 1993Co-Authors: Johan Ormel, M Von Korff, W Van Den Brink, W Katon, Els I Brilman, Tineke OldehinkelAbstract:OBJECTIVES. The purposes of this study were to (1) characterize the Social Disability associated with the common psychiatric illnesses of primary care patients in terms of role dysfunction (self-care, family role, Social role, occupational role) and (2) establish whether severity of psychiatric illness and Disability level show synchrony of change. METHODS. A two-stage sample design was employed. In the first stage, 1994 consecutive attenders of 25 general practitioners were screened on psychiatric illness by their physicians and with the General Health Questionnaire. A stratified random sample (n = 285) with differing probabilities was selected for a second-stage interview. Patients with psychiatric symptoms were reinterviewed 1 and 3.5 years later (n = 143). RESULTS. (1) Disability level among patients was increased (moderately for depression, mildly for anxiety) and was associated with severity of psychiatric illness. (2) Most Disability was found in occupational and Social roles. (3) Change in severit...
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depression anxiety and Social Disability show synchrony of change in primary care patients
American Journal of Public Health, 1993Co-Authors: Johan Ormel, M Von Korff, W Van Den Brink, W Katon, Els I Brilman, Tineke OldehinkelAbstract:Objectives. The purposes of this study were to (1) characterize the Social Disability associated with the common psychiatric illnesses of primary care patients in terms of role dysfunction (self-care, family role, Social role, occupational role) and (2) establish whether severity of psychiatric illness and Disability level show synchrony of change. Methods. A two-stage sample design was employed. In the first stage, 1994 consecutive attenders of 25 general practitioners were screened on psychiatric illness by their physicians and with the General Health Questionnaire. A stratified random sample (n = 285) with differing probabilities was selected for a second-stage interview. Patients with psychiatric symptoms were reinterviewed 1 and 3.5 years later (n = 143). Results. (1) Disability level among patients was increased (moderately for depression, mildly for anxiety) and was associated with severity of psychiatric illness. (2) Most Disability was found in occupational and Social roles. (3) Change in severity of psychiatric illness was concordant with change in level of Disability and was largely invariant across diagnosis (depression, anxiety, mixed anxiety/depression). At follow-up, Disability among improved patients had returned to normal levels. Conclusions, Psychiatric illness in primary care patients is associated with mild to moderate Disability, and severity of psychiatric illness and Disability show synchrony of change.
Tineke Oldehinkel - One of the best experts on this subject based on the ideXlab platform.
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depression anxiety and Social Disability show synchrony of change in primary care patients
American Journal of Public Health, 1993Co-Authors: Johan Ormel, M Von Korff, W Van Den Brink, W Katon, Els I Brilman, Tineke OldehinkelAbstract:OBJECTIVES. The purposes of this study were to (1) characterize the Social Disability associated with the common psychiatric illnesses of primary care patients in terms of role dysfunction (self-care, family role, Social role, occupational role) and (2) establish whether severity of psychiatric illness and Disability level show synchrony of change. METHODS. A two-stage sample design was employed. In the first stage, 1994 consecutive attenders of 25 general practitioners were screened on psychiatric illness by their physicians and with the General Health Questionnaire. A stratified random sample (n = 285) with differing probabilities was selected for a second-stage interview. Patients with psychiatric symptoms were reinterviewed 1 and 3.5 years later (n = 143). RESULTS. (1) Disability level among patients was increased (moderately for depression, mildly for anxiety) and was associated with severity of psychiatric illness. (2) Most Disability was found in occupational and Social roles. (3) Change in severit...
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depression anxiety and Social Disability show synchrony of change in primary care patients
American Journal of Public Health, 1993Co-Authors: Johan Ormel, M Von Korff, W Van Den Brink, W Katon, Els I Brilman, Tineke OldehinkelAbstract:Objectives. The purposes of this study were to (1) characterize the Social Disability associated with the common psychiatric illnesses of primary care patients in terms of role dysfunction (self-care, family role, Social role, occupational role) and (2) establish whether severity of psychiatric illness and Disability level show synchrony of change. Methods. A two-stage sample design was employed. In the first stage, 1994 consecutive attenders of 25 general practitioners were screened on psychiatric illness by their physicians and with the General Health Questionnaire. A stratified random sample (n = 285) with differing probabilities was selected for a second-stage interview. Patients with psychiatric symptoms were reinterviewed 1 and 3.5 years later (n = 143). Results. (1) Disability level among patients was increased (moderately for depression, mildly for anxiety) and was associated with severity of psychiatric illness. (2) Most Disability was found in occupational and Social roles. (3) Change in severity of psychiatric illness was concordant with change in level of Disability and was largely invariant across diagnosis (depression, anxiety, mixed anxiety/depression). At follow-up, Disability among improved patients had returned to normal levels. Conclusions, Psychiatric illness in primary care patients is associated with mild to moderate Disability, and severity of psychiatric illness and Disability show synchrony of change.
Giovanni Benelli - One of the best experts on this subject based on the ideXlab platform.
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chemical composition toxicity and non target effects of pinus kesiya essential oil an eco friendly and novel larvicide against malaria dengue and lymphatic filariasis mosquito vectors
Ecotoxicology and Environmental Safety, 2016Co-Authors: Marimuthu Govindarajan, Mohan Rajeswary, Giovanni BenelliAbstract:Abstract Mosquitoes (Diptera: Culicidae) are vectors of important parasites and pathogens causing death, poverty and Social Disability worldwide, with special reference to tropical and subtropical countries. The overuse of synthetic insecticides to control mosquito vectors lead to resistance, adverse environmental effects and high operational costs. Therefore, the development of eco-friendly control tools is an important public health challenge. In this study, the mosquito larvicidal activity of Pinus kesiya leaf essential oil (EO) was evaluated against the malaria vector Anopheles stephensi, the dengue vector Aedes aegypti and the lymphatic filariasis vector Culex quinquefasciatus . The chemical composition of the EO was analyzed by gas chromatography–mass spectroscopy. GC–MS revealed that the P. kesiya EO contained 18 compounds. Major constituents were α-pinene, β-pinene, myrcene and germacrene D. In acute toxicity assays, the EO showed significant toxicity against early third-stage larvae of An. stephensi, Ae. aegypti and Cx. quinquefasciatus, with LC 50 values of 52, 57, and 62 µg/ml, respectively. Notably, the EO was safer towards several aquatic non-target organisms Anisops bouvieri, Diplonychus indicus and Gambusia affinis , with LC 50 values ranging from 4135 to 8390 µg/ml. Overall, this research adds basic knowledge to develop newer and safer natural larvicides from Pinaceae plants against malaria, dengue and filariasis mosquito vectors.
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chemical composition toxicity and non target effects of pinus kesiya essential oil an eco friendly and novel larvicide against malaria dengue and lymphatic filariasis mosquito vectors
Ecotoxicology and Environmental Safety, 2016Co-Authors: Marimuthu Govindarajan, Mohan Rajeswary, Giovanni BenelliAbstract:Mosquitoes (Diptera: Culicidae) are vectors of important parasites and pathogens causing death, poverty and Social Disability worldwide, with special reference to tropical and subtropical countries. The overuse of synthetic insecticides to control mosquito vectors lead to resistance, adverse environmental effects and high operational costs. Therefore, the development of eco-friendly control tools is an important public health challenge. In this study, the mosquito larvicidal activity of Pinus kesiya leaf essential oil (EO) was evaluated against the malaria vector Anopheles stephensi, the dengue vector Aedes aegypti and the lymphatic filariasis vector Culex quinquefasciatus. The chemical composition of the EO was analyzed by gas chromatography-mass spectroscopy. GC-MS revealed that the P. kesiya EO contained 18 compounds. Major constituents were α-pinene, β-pinene, myrcene and germacrene D. In acute toxicity assays, the EO showed significant toxicity against early third-stage larvae of An. stephensi, Ae. aegypti and Cx. quinquefasciatus, with LC50 values of 52, 57, and 62µg/ml, respectively. Notably, the EO was safer towards several aquatic non-target organisms Anisops bouvieri, Diplonychus indicus and Gambusia affinis, with LC50 values ranging from 4135 to 8390µg/ml. Overall, this research adds basic knowledge to develop newer and safer natural larvicides from Pinaceae plants against malaria, dengue and filariasis mosquito vectors.
M Von Korff - One of the best experts on this subject based on the ideXlab platform.
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Persistent pain and well-being: a World Health Organization Study in Primary Care.
JAMA, 1998Co-Authors: O Gureje, G E Simon, M Von Korff, Richard GaterAbstract:Context.—There is little information on the extent of persistent pain across cultures. Even though pain is a common reason for seeking health care, information on the frequency and impacts of persistent pain among primary care patients is inadequate.Objective.—To assess the prevalence and impact of persistent pain among primary care patients.Design and Setting.—Survey data were collected from representative samples of primary care patients as part of the World Health Organization Collaborative Study of Psychological Problems in General Health Care, conducted in 15 centers in Asia, Africa, Europe, and the Americas.Participants.—Consecutive primary care attendees between the age of majority (typically 18 years) and 65 years were screened (n=25916) and stratified random samples interviewed (n=5438).Main Outcome Measures.—Persistent pain, defined as pain present most of the time for a period of 6 months or more during the prior year, and psychological illness were assessed by the Composite International Diagnostic Interview. Disability was assessed by the Groningen Social Disability Schedule and by activity-limitation days in the prior month.Results.—Across all 15 centers, 22% of primary care patients reported persistent pain, but there was wide variation in prevalence rates across centers (range, 5.5%-33.0%). Relative to patients without persistent pain, pain sufferers were more likely to have an anxiety or depressive disorder (adjusted odds ratio [OR], 4.14; 95% confidence interval [CI], 3.52-4.86), to experience significant activity limitations (adjusted OR, 1.63; 95% CI, 1.41-1.89), and to have unfavorable health perceptions (adjusted OR, 1.26; 95% CI, 1.07-1.49). The relationship between psychological disorder and persistent pain was observed in every center, while the relationship between Disability and persistent pain was inconsistent across centers.Conclusions.—Persistent pain was a commonly reported health problem among primary care patients and was consistently associated with psychological illness across centers. Large variation in frequency and the inconsistent relationship between persistent pain and Disability across centers suggests caution in drawing conclusions about the role of culture in shaping responses to persistent pain when comparisons are based on patient samples drawn from a limited number of health care settings in each culture.
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self report Disability in an international primary care study of psychological illness
Journal of Clinical Epidemiology, 1996Co-Authors: M Von Korff, Johan Ormel, Bedirhan T Ustun, Incila Kaplan, Gregory E SimonAbstract:We assessed the replicability of reliability and validity of a brief self-report Disability scale, adapted from the Medical Outcomes Survey (short form), in a 15-center, cross-national, multilingual study of psychological illness among primary care patients (n = 5438). Across all 15 centers in the World Health Organization Collaborative Study of Psychological Problems in General Health Care, the reliability of the Disability scale was high and individual items were responsive at similar levels of Disability. Self-report Disability was consistently correlated with Disability in work role (including housework) as rated by interviewers according to the Groningen Social Disability Schedule, a semistructured method taking local norms into account. Disability as measured by the self-report questionnaire was also consistently correlated with depressive symptoms as measured by the General Health Questionnaire. At each center, the Disability items formed a moderately to strongly hierarchical (Guttman-like) scale. These findings support the feasibility of using self-report Disability scales in cross-national primary care research.
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depression anxiety and Social Disability show synchrony of change in primary care patients
American Journal of Public Health, 1993Co-Authors: Johan Ormel, M Von Korff, W Van Den Brink, W Katon, Els I Brilman, Tineke OldehinkelAbstract:OBJECTIVES. The purposes of this study were to (1) characterize the Social Disability associated with the common psychiatric illnesses of primary care patients in terms of role dysfunction (self-care, family role, Social role, occupational role) and (2) establish whether severity of psychiatric illness and Disability level show synchrony of change. METHODS. A two-stage sample design was employed. In the first stage, 1994 consecutive attenders of 25 general practitioners were screened on psychiatric illness by their physicians and with the General Health Questionnaire. A stratified random sample (n = 285) with differing probabilities was selected for a second-stage interview. Patients with psychiatric symptoms were reinterviewed 1 and 3.5 years later (n = 143). RESULTS. (1) Disability level among patients was increased (moderately for depression, mildly for anxiety) and was associated with severity of psychiatric illness. (2) Most Disability was found in occupational and Social roles. (3) Change in severit...
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depression anxiety and Social Disability show synchrony of change in primary care patients
American Journal of Public Health, 1993Co-Authors: Johan Ormel, M Von Korff, W Van Den Brink, W Katon, Els I Brilman, Tineke OldehinkelAbstract:Objectives. The purposes of this study were to (1) characterize the Social Disability associated with the common psychiatric illnesses of primary care patients in terms of role dysfunction (self-care, family role, Social role, occupational role) and (2) establish whether severity of psychiatric illness and Disability level show synchrony of change. Methods. A two-stage sample design was employed. In the first stage, 1994 consecutive attenders of 25 general practitioners were screened on psychiatric illness by their physicians and with the General Health Questionnaire. A stratified random sample (n = 285) with differing probabilities was selected for a second-stage interview. Patients with psychiatric symptoms were reinterviewed 1 and 3.5 years later (n = 143). Results. (1) Disability level among patients was increased (moderately for depression, mildly for anxiety) and was associated with severity of psychiatric illness. (2) Most Disability was found in occupational and Social roles. (3) Change in severity of psychiatric illness was concordant with change in level of Disability and was largely invariant across diagnosis (depression, anxiety, mixed anxiety/depression). At follow-up, Disability among improved patients had returned to normal levels. Conclusions, Psychiatric illness in primary care patients is associated with mild to moderate Disability, and severity of psychiatric illness and Disability show synchrony of change.
Johanne Gregersen - One of the best experts on this subject based on the ideXlab platform.
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quality of life in orthognathic surgery patients post surgical improvements in aesthetics and self confidence
Journal of Cranio-maxillofacial Surgery, 2012Co-Authors: Jan Rustemeyer, Johanne GregersenAbstract:Abstract The objective of this prospective study was to assess changes of Quality of Life (QoL) in patients undergoing bimaxillary orthognathic surgery. Questionnaires were based on the Oral Health Impact Profile (OHIP, items OH-1–OH-14) and three additional questions (items AD-1–3), and were completed by patients ( n =50; mean age 26.9±9.9 years) on average 9.1±2.4 months before surgery, and 12.1±1.4 months after surgery, using a scoring scale. Item scores describing functional limitation, physical pain, physical Disability and chewing function did not change significantly, whereas item scores covering psychological discomfort and Social Disability domains revealed significant decreases following surgery. AD-2 "dissatisfying aesthetics" revealed the greatest difference between pre- and post-surgical scores ( p
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quality of life in orthognathic surgery patients post surgical improvements in aesthetics and self confidence
Journal of Cranio-maxillofacial Surgery, 2012Co-Authors: Jan Rustemeyer, Johanne GregersenAbstract:The objective of this prospective study was to assess changes of Quality of Life (QoL) in patients undergoing bimaxillary orthognathic surgery. Questionnaires were based on the Oral Health Impact Profile (OHIP, items OH-1-OH-14) and three additional questions (items AD-1-3), and were completed by patients (n=50; mean age 26.9±9.9 years) on average 9.1±2.4 months before surgery, and 12.1±1.4 months after surgery, using a scoring scale. Item scores describing functional limitation, physical pain, physical Disability and chewing function did not change significantly, whereas item scores covering psychological discomfort and Social Disability domains revealed significant decreases following surgery. AD-2 "dissatisfying aesthetics" revealed the greatest difference between pre- and post-surgical scores (p<0.001). If there was a perception of aesthetic improvement of facial features post-surgery, the benefit in QoL was generally high. The significant correlation of the pre- to post-surgical changes of item OH-5 "self conscious" to nearly all other item changes suggested that OH-5 was the most sensitive indicator for post-surgical improvement of QoL. Psychological factors and aesthetics exerted a strong influence on the patients' QoL, and determined major changes more than functional aspects did.