The Experts below are selected from a list of 93 Experts worldwide ranked by ideXlab platform
Jan A. C. Hontelez - One of the best experts on this subject based on the ideXlab platform.
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Socioeconomic Benefit to individuals of achieving 2020 targets for four neglected tropical diseases controlled eliminated by innovative and intensified disease management human african trypanosomiasis leprosy visceral leishmaniasis chagas disease
PLOS Neglected Tropical Diseases, 2018Co-Authors: Edeltraud J. Lenk, William K. Redekop, Marianne Luyendijk, Christopher Fitzpatrick, Louis W. Niessen, Wilma A. Stolk, Fabrizio Tediosi, Adriana J. Rijnsburger, Roel Bakker, Jan A. C. HontelezAbstract:markdownabstract__Background__ The control or elimination of neglected tropical diseases (NTDs) has targets defined by the WHO for 2020, reinforced by the 2012 London Declaration. We estimated the economic impact to individuals of meeting these targets for human African trypanosomiasis, leprosy, visceral leishmaniasis and Chagas disease, NTDs controlled or eliminated by innovative and intensified disease management (IDM). __Methods__ A systematic literature review identified information on productivity loss and out-of-pocket payments (OPPs) related to these NTDs, which were combined with projections of the number of people suffering from each NTD, country and year for 2011±2020 and 2021±2030. The ideal scenario in which the WHO's 2020 targets are met was compared with a counterfactual scenario that assumed the situation of 1990 stayed unaltered. Economic Benefit equaled the difference between the two scenarios. Values are reported in 2005 US$, purchasing power parity-adjusted, discounted at 3% per annum from 2010. Probabilistic sensitivity analyses were used to quantify the degree of uncertainty around the base-case impact estimate. __Results__ The total global productivity gained for the four IDM-NTDs was I$ 23.1 (I$ 15.9 ±I$ 34.0) billion in 2011±2020 and I$ 35.9 (I$ 25.0 ±I$ 51.9) billion in 2021±2030 (2.5th and 97.5th percentiles in brackets), corresponding to US$ 10.7 billion (US$ 7.4 ±US$ 15.7) and US$ 16.6 billion (US$ 11.6 ±US$ 24.0). Reduction in OPPs was I$ 14 billion (US$ 6.7 billion) and I$ 18 billion (US$ 10.4 billion) for the same periods. __Conclusions__ We faced important limitations to our work, such as finding no OPPs for leprosy. We had to combine limited data from various sources, heterogeneous background, and of variable quality. Nevertheless, based on conservative assumptions and subsequent uncertainty analyses, we estimate that the Benefits of achieving the targets are considerable. Under plausible scenarios, the economic Benefits far exceed the necessary investments by endemic country governments and their development partners. Given the higher frequency of NTDs among the poorest households, these investments represent good value for money in the effort to improve well-being, distribute the world's prosperity more equitably and reduce inequity.
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The Socioeconomic Benefit to Individuals of Achieving the 2020 Targets for Five Preventive Chemotherapy Neglected Tropical Diseases.
PLOS Neglected Tropical Diseases, 2017Co-Authors: William K. Redekop, Edeltraud J. Lenk, Marianne Luyendijk, Christopher Fitzpatrick, Louis W. Niessen, Wilma A. Stolk, Fabrizio Tediosi, Adriana J. Rijnsburger, Roel Bakker, Jan A. C. HontelezAbstract:markdownabstractBackground: Lymphatic filariasis (LF), onchocerciasis, schistosomiasis, soil-transmitted helminths (STH) and trachoma represent the five most prevalent neglected tropical diseases (NTDs). They can be controlled or eliminated by means of safe and cost-effective interventions delivered through programs of Mass Drug Administration (MDA)—also named Preventive Chemotherapy (PCT). The WHO defined targets for NTD control/elimination by 2020, reinforced by the 2012 London Declaration, which, if achieved, would result in dramatic health gains. We estimated the potential economic Benefit of achieving these targets, focusing specifically on productivity and out-of-pocket payments. Methods: Productivity loss was calculated by combining disease frequency with productivity loss from the disease, from the perspective of affected individuals. Productivity gain was calculated by deducting the total loss expected in the target achievement scenario from the loss in a counterfactual scenario where it was assumed the pre-intervention situation in 1990 regarding NTDs would continue unabated until 2030. Economic Benefits from out-of-pocket payments (OPPs) were calculated similarly. Benefits are reported in 2005 US$ (purchasing power parity-adjusted and discounted at 3% per annum from 2010). Sensitivity analyses were used to assess the influence of changes in input parameters. Results: The economic Benefit from productivity gain was estimated to be I$251 billion in 2011–2020 and I$313 billion in 2021–2030, considerably greater than the total OPPs averted of I$0.72 billion and I$0.96 billion in the same periods. The net Benefit is expected to be US$ 27.4 and US$ 42.8 for every dollar invested during the same periods. Impact varies between NTDs and regions, since it is determined by disease prevalence and extent of disease-related productivity loss. Conclusion: Achieving the PCT-NTD targets for 2020 will yield significant economic Benefits to affected individuals. Despite large uncertainty, these Benefits far exceed the investment required by governments and their development partners within all reasonable scenarios. Given the concentration of the NTDs among the poorest households, these investments represent good value for money in efforts to share the world’s prosperity and reduce inequity.
Di Jin - One of the best experts on this subject based on the ideXlab platform.
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On the measurement of Socioeconomic Benefits of integrated coastal management (ICM): Application to Xiamen, China
Ocean & Coastal Management, 2006Co-Authors: Benrong Peng, Huasheng Hong, Xiongzhi Xue, Di JinAbstract:We develop a systematic approach for the measurement of overall Socioeconomic Benefits associated with an integrated coastal management (ICM) program. The analytical framework includes multiple marine industry sectors (e.g., ocean shipping and commercial fisheries) as well as environmental sectors (e.g., coastal erosion). The net Benefit measure captures both economic and environmental effects. We apply our analytical model to Xiamen, China, using empirical data from 1992 to 2001. Results of the case study show that the implementation of ICM program in Xiamen has led to a significant increase (over 40%) in annual Socioeconomic Benefit from its marine sectors. Thus, the Xiamen ICM program has been effective in achieving sustainable development.
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On the measurement of Socioeconomic Benefits of integrated coastal management (ICM): Application to Xiamen, China
Ocean & Coastal Management, 2006Co-Authors: Benrong Peng, Huasheng Hong, Xiongzhi Xue, Di JinAbstract:We develop a systematic approach for the measurement of overall Socioeconomic Benefits associated with an integrated coastal management (ICM) program. The analytical framework includes multiple marine industry sectors (e.g., ocean shipping and commercial fisheries) as well as environmental sectors (e.g., coastal erosion). The net Benefit measure captures both economic and environmental effects. We apply our analytical model to Xiamen, China, using empirical data from 1992 to 2001. Results of the case study show that the implementation of ICM program in Xiamen has led to a significant increase (over 40%) in annual Socioeconomic Benefit from its marine sectors. Thus, the Xiamen ICM program has been effective in achieving sustainable development. (c) 2006 Published by Elsevier Ltd
Edeltraud J. Lenk - One of the best experts on this subject based on the ideXlab platform.
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Socioeconomic Benefit to individuals of achieving 2020 targets for four neglected tropical diseases controlled eliminated by innovative and intensified disease management human african trypanosomiasis leprosy visceral leishmaniasis chagas disease
PLOS Neglected Tropical Diseases, 2018Co-Authors: Edeltraud J. Lenk, William K. Redekop, Marianne Luyendijk, Christopher Fitzpatrick, Louis W. Niessen, Wilma A. Stolk, Fabrizio Tediosi, Adriana J. Rijnsburger, Roel Bakker, Jan A. C. HontelezAbstract:markdownabstract__Background__ The control or elimination of neglected tropical diseases (NTDs) has targets defined by the WHO for 2020, reinforced by the 2012 London Declaration. We estimated the economic impact to individuals of meeting these targets for human African trypanosomiasis, leprosy, visceral leishmaniasis and Chagas disease, NTDs controlled or eliminated by innovative and intensified disease management (IDM). __Methods__ A systematic literature review identified information on productivity loss and out-of-pocket payments (OPPs) related to these NTDs, which were combined with projections of the number of people suffering from each NTD, country and year for 2011±2020 and 2021±2030. The ideal scenario in which the WHO's 2020 targets are met was compared with a counterfactual scenario that assumed the situation of 1990 stayed unaltered. Economic Benefit equaled the difference between the two scenarios. Values are reported in 2005 US$, purchasing power parity-adjusted, discounted at 3% per annum from 2010. Probabilistic sensitivity analyses were used to quantify the degree of uncertainty around the base-case impact estimate. __Results__ The total global productivity gained for the four IDM-NTDs was I$ 23.1 (I$ 15.9 ±I$ 34.0) billion in 2011±2020 and I$ 35.9 (I$ 25.0 ±I$ 51.9) billion in 2021±2030 (2.5th and 97.5th percentiles in brackets), corresponding to US$ 10.7 billion (US$ 7.4 ±US$ 15.7) and US$ 16.6 billion (US$ 11.6 ±US$ 24.0). Reduction in OPPs was I$ 14 billion (US$ 6.7 billion) and I$ 18 billion (US$ 10.4 billion) for the same periods. __Conclusions__ We faced important limitations to our work, such as finding no OPPs for leprosy. We had to combine limited data from various sources, heterogeneous background, and of variable quality. Nevertheless, based on conservative assumptions and subsequent uncertainty analyses, we estimate that the Benefits of achieving the targets are considerable. Under plausible scenarios, the economic Benefits far exceed the necessary investments by endemic country governments and their development partners. Given the higher frequency of NTDs among the poorest households, these investments represent good value for money in the effort to improve well-being, distribute the world's prosperity more equitably and reduce inequity.
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The Socioeconomic Benefit to Individuals of Achieving the 2020 Targets for Five Preventive Chemotherapy Neglected Tropical Diseases.
PLOS Neglected Tropical Diseases, 2017Co-Authors: William K. Redekop, Edeltraud J. Lenk, Marianne Luyendijk, Christopher Fitzpatrick, Louis W. Niessen, Wilma A. Stolk, Fabrizio Tediosi, Adriana J. Rijnsburger, Roel Bakker, Jan A. C. HontelezAbstract:markdownabstractBackground: Lymphatic filariasis (LF), onchocerciasis, schistosomiasis, soil-transmitted helminths (STH) and trachoma represent the five most prevalent neglected tropical diseases (NTDs). They can be controlled or eliminated by means of safe and cost-effective interventions delivered through programs of Mass Drug Administration (MDA)—also named Preventive Chemotherapy (PCT). The WHO defined targets for NTD control/elimination by 2020, reinforced by the 2012 London Declaration, which, if achieved, would result in dramatic health gains. We estimated the potential economic Benefit of achieving these targets, focusing specifically on productivity and out-of-pocket payments. Methods: Productivity loss was calculated by combining disease frequency with productivity loss from the disease, from the perspective of affected individuals. Productivity gain was calculated by deducting the total loss expected in the target achievement scenario from the loss in a counterfactual scenario where it was assumed the pre-intervention situation in 1990 regarding NTDs would continue unabated until 2030. Economic Benefits from out-of-pocket payments (OPPs) were calculated similarly. Benefits are reported in 2005 US$ (purchasing power parity-adjusted and discounted at 3% per annum from 2010). Sensitivity analyses were used to assess the influence of changes in input parameters. Results: The economic Benefit from productivity gain was estimated to be I$251 billion in 2011–2020 and I$313 billion in 2021–2030, considerably greater than the total OPPs averted of I$0.72 billion and I$0.96 billion in the same periods. The net Benefit is expected to be US$ 27.4 and US$ 42.8 for every dollar invested during the same periods. Impact varies between NTDs and regions, since it is determined by disease prevalence and extent of disease-related productivity loss. Conclusion: Achieving the PCT-NTD targets for 2020 will yield significant economic Benefits to affected individuals. Despite large uncertainty, these Benefits far exceed the investment required by governments and their development partners within all reasonable scenarios. Given the concentration of the NTDs among the poorest households, these investments represent good value for money in efforts to share the world’s prosperity and reduce inequity.
William K. Redekop - One of the best experts on this subject based on the ideXlab platform.
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Socioeconomic Benefit to individuals of achieving 2020 targets for four neglected tropical diseases controlled eliminated by innovative and intensified disease management human african trypanosomiasis leprosy visceral leishmaniasis chagas disease
PLOS Neglected Tropical Diseases, 2018Co-Authors: Edeltraud J. Lenk, William K. Redekop, Marianne Luyendijk, Christopher Fitzpatrick, Louis W. Niessen, Wilma A. Stolk, Fabrizio Tediosi, Adriana J. Rijnsburger, Roel Bakker, Jan A. C. HontelezAbstract:markdownabstract__Background__ The control or elimination of neglected tropical diseases (NTDs) has targets defined by the WHO for 2020, reinforced by the 2012 London Declaration. We estimated the economic impact to individuals of meeting these targets for human African trypanosomiasis, leprosy, visceral leishmaniasis and Chagas disease, NTDs controlled or eliminated by innovative and intensified disease management (IDM). __Methods__ A systematic literature review identified information on productivity loss and out-of-pocket payments (OPPs) related to these NTDs, which were combined with projections of the number of people suffering from each NTD, country and year for 2011±2020 and 2021±2030. The ideal scenario in which the WHO's 2020 targets are met was compared with a counterfactual scenario that assumed the situation of 1990 stayed unaltered. Economic Benefit equaled the difference between the two scenarios. Values are reported in 2005 US$, purchasing power parity-adjusted, discounted at 3% per annum from 2010. Probabilistic sensitivity analyses were used to quantify the degree of uncertainty around the base-case impact estimate. __Results__ The total global productivity gained for the four IDM-NTDs was I$ 23.1 (I$ 15.9 ±I$ 34.0) billion in 2011±2020 and I$ 35.9 (I$ 25.0 ±I$ 51.9) billion in 2021±2030 (2.5th and 97.5th percentiles in brackets), corresponding to US$ 10.7 billion (US$ 7.4 ±US$ 15.7) and US$ 16.6 billion (US$ 11.6 ±US$ 24.0). Reduction in OPPs was I$ 14 billion (US$ 6.7 billion) and I$ 18 billion (US$ 10.4 billion) for the same periods. __Conclusions__ We faced important limitations to our work, such as finding no OPPs for leprosy. We had to combine limited data from various sources, heterogeneous background, and of variable quality. Nevertheless, based on conservative assumptions and subsequent uncertainty analyses, we estimate that the Benefits of achieving the targets are considerable. Under plausible scenarios, the economic Benefits far exceed the necessary investments by endemic country governments and their development partners. Given the higher frequency of NTDs among the poorest households, these investments represent good value for money in the effort to improve well-being, distribute the world's prosperity more equitably and reduce inequity.
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The Socioeconomic Benefit to Individuals of Achieving the 2020 Targets for Five Preventive Chemotherapy Neglected Tropical Diseases.
PLOS Neglected Tropical Diseases, 2017Co-Authors: William K. Redekop, Edeltraud J. Lenk, Marianne Luyendijk, Christopher Fitzpatrick, Louis W. Niessen, Wilma A. Stolk, Fabrizio Tediosi, Adriana J. Rijnsburger, Roel Bakker, Jan A. C. HontelezAbstract:markdownabstractBackground: Lymphatic filariasis (LF), onchocerciasis, schistosomiasis, soil-transmitted helminths (STH) and trachoma represent the five most prevalent neglected tropical diseases (NTDs). They can be controlled or eliminated by means of safe and cost-effective interventions delivered through programs of Mass Drug Administration (MDA)—also named Preventive Chemotherapy (PCT). The WHO defined targets for NTD control/elimination by 2020, reinforced by the 2012 London Declaration, which, if achieved, would result in dramatic health gains. We estimated the potential economic Benefit of achieving these targets, focusing specifically on productivity and out-of-pocket payments. Methods: Productivity loss was calculated by combining disease frequency with productivity loss from the disease, from the perspective of affected individuals. Productivity gain was calculated by deducting the total loss expected in the target achievement scenario from the loss in a counterfactual scenario where it was assumed the pre-intervention situation in 1990 regarding NTDs would continue unabated until 2030. Economic Benefits from out-of-pocket payments (OPPs) were calculated similarly. Benefits are reported in 2005 US$ (purchasing power parity-adjusted and discounted at 3% per annum from 2010). Sensitivity analyses were used to assess the influence of changes in input parameters. Results: The economic Benefit from productivity gain was estimated to be I$251 billion in 2011–2020 and I$313 billion in 2021–2030, considerably greater than the total OPPs averted of I$0.72 billion and I$0.96 billion in the same periods. The net Benefit is expected to be US$ 27.4 and US$ 42.8 for every dollar invested during the same periods. Impact varies between NTDs and regions, since it is determined by disease prevalence and extent of disease-related productivity loss. Conclusion: Achieving the PCT-NTD targets for 2020 will yield significant economic Benefits to affected individuals. Despite large uncertainty, these Benefits far exceed the investment required by governments and their development partners within all reasonable scenarios. Given the concentration of the NTDs among the poorest households, these investments represent good value for money in efforts to share the world’s prosperity and reduce inequity.
Benrong Peng - One of the best experts on this subject based on the ideXlab platform.
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On the measurement of Socioeconomic Benefits of integrated coastal management (ICM): Application to Xiamen, China
Ocean & Coastal Management, 2006Co-Authors: Benrong Peng, Huasheng Hong, Xiongzhi Xue, Di JinAbstract:We develop a systematic approach for the measurement of overall Socioeconomic Benefits associated with an integrated coastal management (ICM) program. The analytical framework includes multiple marine industry sectors (e.g., ocean shipping and commercial fisheries) as well as environmental sectors (e.g., coastal erosion). The net Benefit measure captures both economic and environmental effects. We apply our analytical model to Xiamen, China, using empirical data from 1992 to 2001. Results of the case study show that the implementation of ICM program in Xiamen has led to a significant increase (over 40%) in annual Socioeconomic Benefit from its marine sectors. Thus, the Xiamen ICM program has been effective in achieving sustainable development.
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On the measurement of Socioeconomic Benefits of integrated coastal management (ICM): Application to Xiamen, China
Ocean & Coastal Management, 2006Co-Authors: Benrong Peng, Huasheng Hong, Xiongzhi Xue, Di JinAbstract:We develop a systematic approach for the measurement of overall Socioeconomic Benefits associated with an integrated coastal management (ICM) program. The analytical framework includes multiple marine industry sectors (e.g., ocean shipping and commercial fisheries) as well as environmental sectors (e.g., coastal erosion). The net Benefit measure captures both economic and environmental effects. We apply our analytical model to Xiamen, China, using empirical data from 1992 to 2001. Results of the case study show that the implementation of ICM program in Xiamen has led to a significant increase (over 40%) in annual Socioeconomic Benefit from its marine sectors. Thus, the Xiamen ICM program has been effective in achieving sustainable development. (c) 2006 Published by Elsevier Ltd