The Experts below are selected from a list of 57 Experts worldwide ranked by ideXlab platform
Abhishek Ghosh - One of the best experts on this subject based on the ideXlab platform.
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Somatic symptom and related disorders in asians and asian americans
Asian Journal of Psychiatry, 2014Co-Authors: Sandeep Grover, Abhishek GhoshAbstract:Abstract Somatic Manifestation is common in the Asian population. The frequent occurrence of Somatic symptom and related disorders among Asians could well be explained by an overt emphasis on ‘Somatic’ idioms of distress on the one hand, and unacceptability and stigma attached to psychological expression of distress on the other. Assessment and diagnosis of somatoform disorders is complicated by the scarcity of cross-culturally validated instruments. Likewise, management is also based on Western literature in which psychological interventions override pharmacological treatment. DSM-5 has broadened the scope of somatoform disorders and emphasizes the concept rather than simply counting symptoms. These changes are expected to have a positive impact cross-culturally.
Eiji Yano - One of the best experts on this subject based on the ideXlab platform.
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Prediction of major depression in Japanese adults: Somatic Manifestation of depression in annual health examinations.
Journal of affective disorders, 2005Co-Authors: Mutsuhiro Nakao, Eiji YanoAbstract:Abstract Background The present study examined whether Somatic symptoms found in annual health examinations, could be predictive of major depression in the ensuing year. Method Subjects analyzed were 1027 non-major-depressive workers (706 men, mean age 35) attending annual health examinations at a research institute. All were Japanese and found not to be suffering from major depression when interviewed, according to the semi-structured interviews of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). A self-administered questionnaire containing items relating to twelve major Somatic symptoms was completed by all the subjects. The same DSM-IV interviews for the diagnosis of major depression were conducted to calculate the odds ratio of baseline variables for depressive and Somatic symptoms, physical examination items, and health-related life-styles for the prediction of major depression in the ensuing year. Results The prevalence of major depression in the ensuing year was 2.5%. For four Somatic symptoms (fatigue, lower back pain, dizziness, and nausea), the prevalence was higher (all p Limitations It is possible that Somatic Manifestations of depression are culturally bound phenomena and results might be generalizable only to Japanese workers. Conclusion Somatic symptoms reported at annual health examinations may be useful indicators for predicting major depression.
Sandeep Grover - One of the best experts on this subject based on the ideXlab platform.
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Somatic symptom and related disorders in asians and asian americans
Asian Journal of Psychiatry, 2014Co-Authors: Sandeep Grover, Abhishek GhoshAbstract:Abstract Somatic Manifestation is common in the Asian population. The frequent occurrence of Somatic symptom and related disorders among Asians could well be explained by an overt emphasis on ‘Somatic’ idioms of distress on the one hand, and unacceptability and stigma attached to psychological expression of distress on the other. Assessment and diagnosis of somatoform disorders is complicated by the scarcity of cross-culturally validated instruments. Likewise, management is also based on Western literature in which psychological interventions override pharmacological treatment. DSM-5 has broadened the scope of somatoform disorders and emphasizes the concept rather than simply counting symptoms. These changes are expected to have a positive impact cross-culturally.
Mutsuhiro Nakao - One of the best experts on this subject based on the ideXlab platform.
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Prediction of major depression in Japanese adults: Somatic Manifestation of depression in annual health examinations.
Journal of affective disorders, 2005Co-Authors: Mutsuhiro Nakao, Eiji YanoAbstract:Abstract Background The present study examined whether Somatic symptoms found in annual health examinations, could be predictive of major depression in the ensuing year. Method Subjects analyzed were 1027 non-major-depressive workers (706 men, mean age 35) attending annual health examinations at a research institute. All were Japanese and found not to be suffering from major depression when interviewed, according to the semi-structured interviews of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). A self-administered questionnaire containing items relating to twelve major Somatic symptoms was completed by all the subjects. The same DSM-IV interviews for the diagnosis of major depression were conducted to calculate the odds ratio of baseline variables for depressive and Somatic symptoms, physical examination items, and health-related life-styles for the prediction of major depression in the ensuing year. Results The prevalence of major depression in the ensuing year was 2.5%. For four Somatic symptoms (fatigue, lower back pain, dizziness, and nausea), the prevalence was higher (all p Limitations It is possible that Somatic Manifestations of depression are culturally bound phenomena and results might be generalizable only to Japanese workers. Conclusion Somatic symptoms reported at annual health examinations may be useful indicators for predicting major depression.
Rafael Maldonado - One of the best experts on this subject based on the ideXlab platform.
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Study of the behavioural responses related to the potential addictive properties of MDMA in mice
Naunyn-Schmiedeberg's Archives of Pharmacology, 2004Co-Authors: Patricia Robledo, Graciela Balerio, Fernando Berrendero, Rafael MaldonadoAbstract:We investigated several behavioural responses induced by repeated administration of MDMA in mice that could be related to its potential abuse liability. Mice treated with MDMA at the dose of 10 mg/kg displayed a significant conditioned place preference with respect to saline treated controls, while lower doses (0.3, 1.0, 3.3 mg/kg) had no effect. The development of physical dependence was also investigated. Mice were treated with MDMA (10 mg/kg) twice daily for 5 days. On day 6, following a single administration of MDMA mice received the following monoaminergic antagonists: metergoline (0.1 and 1 mg/kg), ritanserin (0.25 and 1 mg/kg), timolol (2 and 10 mg/kg), prazosin (0.25 and 1 mg/kg), SCH 23390 (0.05 and 0.25 mg/kg), raclopride (0.1 and 0.5 mg/kg) or vehicle, and several Somatic Manifestations of withdrawal were evaluated for 45 min. Metergoline induced paw tremor, face rubbing, as well as an increase in locomotor activity in mice chronically treated with MDMA. Ritanserin, and timolol induced only paw tremor, while SCH 23390 and raclopride did not produce any Somatic Manifestation indicative of abstinence. The possible modification of the rewarding properties of MDMA (10 mg/kg) by the monoaminergic antagonists producing the most relevant Somatic signs of withdrawal namely, metergoline (0.1 and 1 mg/kg) and timolol (2 and 10 mg/kg) were tested in the conditioned place preference paradigm. Results showed that metergoline did not significantly modify the rewarding properties of MDMA, whereas only the highest dose of timolol was able to decrease MDMA reward. No signs of dopaminergic neurotoxicity were observed following chronic treatment with MDMA as revealed by [^3H] mazindol binding. The possible motivational and affective components of the withdrawal syndrome were assessed in the suppression of operant responding for food, the conditioned place aversion, and the lit/dark paradigms. Results showed that the Somatic symptoms observed were not accompanied by any aversive/dysphoric or anxiogenic-like behaviours. These results reveal the rewarding properties of MDMA in mice, and suggest that chronic MDMA administration does not induce classical Manifestations of physical dependence in mice.