The Experts below are selected from a list of 261 Experts worldwide ranked by ideXlab platform
Dana A. Weiss - One of the best experts on this subject based on the ideXlab platform.
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Transitional Urology Care for Patients with Spina bifida
Current Pediatrics Reports, 2018Co-Authors: Robert C. Kovell, Alexander Skokan, Dana A. WeissAbstract:Purpose of Review Patients with Spina bifida require urologic care and follow-up throughout all phases of life. The transition from adolescence to adult care represents a high-risk time for these individuals and their families and can be challenging for providers. In this review, we seek to analyze the literature on Spina bifida patients regarding issues pertinent to transition of their urologic care to adult clinics, providers, and hospitals, and to summarize the experience in the field to date. Recent Findings Experience in transitioning Spina bifida patients to adult care is increasing. Efforts to better define the factors that determine successful transition and affect long-term care outcomes are ongoing. Summary A growing body of literature exists regarding Spina bifida patients transitioning to adult care, but further experience and research will be required to define optimal ways to manage and provide care for these individuals in the future.
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Transitional Urology Care for Patients with Spina bifida
Current Pediatrics Reports, 2018Co-Authors: Robert C. Kovell, Alexander Skokan, Dana A. WeissAbstract:Patients with Spina bifida require urologic care and follow-up throughout all phases of life. The transition from adolescence to adult care represents a high-risk time for these individuals and their families and can be challenging for providers. In this review, we seek to analyze the literature on Spina bifida patients regarding issues pertinent to transition of their urologic care to adult clinics, providers, and hospitals, and to summarize the experience in the field to date. Experience in transitioning Spina bifida patients to adult care is increasing. Efforts to better define the factors that determine successful transition and affect long-term care outcomes are ongoing. A growing body of literature exists regarding Spina bifida patients transitioning to adult care, but further experience and research will be required to define optimal ways to manage and provide care for these individuals in the future.
Robert C. Kovell - One of the best experts on this subject based on the ideXlab platform.
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Transitional Urology Care for Patients with Spina bifida
Current Pediatrics Reports, 2018Co-Authors: Robert C. Kovell, Alexander Skokan, Dana A. WeissAbstract:Purpose of Review Patients with Spina bifida require urologic care and follow-up throughout all phases of life. The transition from adolescence to adult care represents a high-risk time for these individuals and their families and can be challenging for providers. In this review, we seek to analyze the literature on Spina bifida patients regarding issues pertinent to transition of their urologic care to adult clinics, providers, and hospitals, and to summarize the experience in the field to date. Recent Findings Experience in transitioning Spina bifida patients to adult care is increasing. Efforts to better define the factors that determine successful transition and affect long-term care outcomes are ongoing. Summary A growing body of literature exists regarding Spina bifida patients transitioning to adult care, but further experience and research will be required to define optimal ways to manage and provide care for these individuals in the future.
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Transitional Urology Care for Patients with Spina bifida
Current Pediatrics Reports, 2018Co-Authors: Robert C. Kovell, Alexander Skokan, Dana A. WeissAbstract:Patients with Spina bifida require urologic care and follow-up throughout all phases of life. The transition from adolescence to adult care represents a high-risk time for these individuals and their families and can be challenging for providers. In this review, we seek to analyze the literature on Spina bifida patients regarding issues pertinent to transition of their urologic care to adult clinics, providers, and hospitals, and to summarize the experience in the field to date. Experience in transitioning Spina bifida patients to adult care is increasing. Efforts to better define the factors that determine successful transition and affect long-term care outcomes are ongoing. A growing body of literature exists regarding Spina bifida patients transitioning to adult care, but further experience and research will be required to define optimal ways to manage and provide care for these individuals in the future.
Jack M Fletcher - One of the best experts on this subject based on the ideXlab platform.
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Spina bifida
Nature Reviews Disease Primers, 2015Co-Authors: Andrew J. Copp, Jack M Fletcher, N. Scott Adzick, Lyn S. Chitty, Grayson N. Holmbeck, Gary M. ShawAbstract:Spina bifida is a congenital disorder caused by failed closure of the neural tube, which leads to sensory, motor and cognitive dysfunction. Copp et al . discuss the prevalence and pathogenesis of Spina bifida, as well as preventive actions, diagnostic methods and treatment options. Spina bifida is a birth defect in which the vertebral column is open, often with Spinal cord involvement. The most clinically significant subtype is myelomeningocele (open Spina bifida), which is a condition characterized by failure of the lumbosacral Spinal neural tube to close during embryonic development. The exposed neural tissue degenerates in utero , resulting in neurological deficit that varies with the level of the lesion. Occurring in approximately 1 per 1,000 births worldwide, myelomeningocele is one of the most common congenital malformations, but its cause is largely unknown. The genetic component is estimated at 60–70%, but few causative genes have been identified to date, despite much information from mouse models. Non-genetic maternal risk factors include reduced folate intake, anticonvulsant therapy, diabetes mellitus and obesity. Primary prevention by periconceptional supplementation with folic acid has been demonstrated in clinical trials, leading to food fortification programmes in many countries. Prenatal diagnosis is achieved by ultrasonography, enabling women to seek termination of pregnancy. Individuals who survive to birth have their lesions closed surgically, with subsequent management of associated defects, including the Chiari II brain malformation, hydrocephalus, and urological and orthopaedic sequelae. Fetal surgical repair of myelomeningocele has been associated with improved early neurological outcome compared with postnatal operation. Myelomeningocele affects quality of life during childhood, adolescence and adulthood, posing a challenge for individuals, families and society as a whole. For an illustrated summary of this Primer, visit: http://go.nature.com/fK9XNa
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Introduction: Spina bifida—A multidisciplinary perspective
Developmental Disabilities Research Reviews, 2010Co-Authors: Jack M Fletcher, Timothy J BreiAbstract:Spina bifida is the most common birth defect affecting the central nervous system (CNS) and is often characterized as the most complex birth defect compatible with survival [Liptak and El Samra, 2010]. Because of its complexity, the diagnosis and treatment of infants born with Spina bifida begins before birth and through adulthood, involving multiple disciplines. Not surprisingly, research has flourished across several domains over the past decade. The purpose of this special issue of Developmental Disabilities Research Reviews is to systematically review research on Spina bifida within different domains in an effort to promote integration and awareness of this research across disciplines involved directly with Spina bifida. In addition, we hope to increase the awareness of contemporary research and treatment strategies for researchers and practitioners involved with other developmental disabilities. Although some aspects of Spina bifida have been reviewed as part of previous issues, this is the first issue of the journal specifically devoted to Spina bifida since an issue on neural tube defects edited by Sells [1998].
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introduction Spina bifida a multidisciplinary perspective
Developmental Disabilities Research Reviews, 2010Co-Authors: Jack M Fletcher, Timothy J BreiAbstract:Spina bifida is the most common birth defect affecting the central nervous system (CNS) and is often characterized as the most complex birth defect compatible with survival [Liptak and El Samra, 2010]. Because of its complexity, the diagnosis and treatment of infants born with Spina bifida begins before birth and through adulthood, involving multiple disciplines. Not surprisingly, research has flourished across several domains over the past decade. The purpose of this special issue of Developmental Disabilities Research Reviews is to systematically review research on Spina bifida within different domains in an effort to promote integration and awareness of this research across disciplines involved directly with Spina bifida. In addition, we hope to increase the awareness of contemporary research and treatment strategies for researchers and practitioners involved with other developmental disabilities. Although some aspects of Spina bifida have been reviewed as part of previous issues, this is the first issue of the journal specifically devoted to Spina bifida since an issue on neural tube defects edited by Sells [1998].
Eun Kyoung Choi - One of the best experts on this subject based on the ideXlab platform.
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Sexual function and qualify of life in women with Spina bifida: Are the women with Spina bifida satisfied with their sexual activity?
Neurourology and Urodynamics, 2018Co-Authors: Eun Kyoung Choi, Yoonhye JiAbstract:AIMS: As the life expectancy of persons with Spina bifida increases, sexual life in adulthood presents a considerable challenge for this population. The purpose of this study was to evaluate the sexual function of young women with Spina bifida and its impact on their quality of life (QOL). METHODS: To assess sexual function and QOL by using self-administered questionnaires (Female Sexual Function Index [FSFI] and 36-Item Short Form Health Survey) in young women with Spina bifida, we collected data from 44 young women with Spina bifida between June 2013 and October 2013 at the Spina bifida clinic of our hospital. RESULTS: Sexual dysfunction was noted in 55.5% of women with Spina bifida who had sexual activity in the previous month. In sexually active women, the diagnosis, ventriculoperitoneal shunt in situ, mobility, and clean intermittent catheterization did not show a significant difference between each subdomain (desire, arousal, lubrication, orgasm, satisfaction, and pain) and the total FSFI score. However, women who did not have urinary incontinence experienced better sexual function in terms of lubrication and pain scores (P = 0.033 and P = 0.026, respectively). Both the physical and mental composites of QOL were positively weakly correlated with the arousal score of FSFI (r = 0.455, P = 0.044 and r = 0.507, P = 0.023, respectively). CONCLUSIONS: More than half of sexually active women with Spina bifida experience sexual dysfunction. Therefore, health-care providers should pay attention to the symptoms and their management.
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Spina bifida occulta not to be overlooked in children with nocturnal enuresis
International Journal of Urology, 2013Co-Authors: Sang Hee Shin, Young Jae Im, Eun Kyoung ChoiAbstract:Objective Previous reports have suggested that the incidence of Spina bifida occulta in patients with nocturnal enuresis is higher than in the general population. However, the effect of Spina bifida occulta on the response to nocturnal enuresis treatment is controversial. The purpose of this study was to investigate the relationship between Spina bifida occulta and response to treatment of nocturnal enuresis. Methods Between 2006 and 2009, the records of 160 children with nocturnal enuresis were reviewed. Children with other organic urological disease or symptoms suggestive of Spinal dysraphism were excluded. Plain radiography for the kidney–ureter–bladder was carried out before the start of the nocturnal enuresis treatment. Response to treatment of children with and without Spina bifida occulta was compared. Results Of 160 children, 53 were girls; the mean age was 7.8 ± 2.06 years. The mean duration of treatment was 8.7 ± 9.29 months. Spina bifida occulta was detected in 43 children (26.9%). Spina bifida occulta affected L4 in four children, L5 in 12 children, S1 in 26 children and S2 in one child. There was a significant difference between the Spina bifida occulta and non-Spina bifida occulta groups in terms of outcome (P = 0.002), with a complete response more likely in children without Spina bifida occulta (P = 0.005). None of the children with primary non-mono symptomatic nocturnal enuresis and Spina bifida occulta showed a complete response. Conclusions The presence of Spina bifida occulta significantly affects the response to treatment in patients with nocturnal enuresis. Thus, verifying Spina bifida occulta in this patient population can facilitate the prediction of the response to nocturnal enuresis treatment.
Timothy J Brei - One of the best experts on this subject based on the ideXlab platform.
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Introduction: Spina bifida—A multidisciplinary perspective
Developmental Disabilities Research Reviews, 2010Co-Authors: Jack M Fletcher, Timothy J BreiAbstract:Spina bifida is the most common birth defect affecting the central nervous system (CNS) and is often characterized as the most complex birth defect compatible with survival [Liptak and El Samra, 2010]. Because of its complexity, the diagnosis and treatment of infants born with Spina bifida begins before birth and through adulthood, involving multiple disciplines. Not surprisingly, research has flourished across several domains over the past decade. The purpose of this special issue of Developmental Disabilities Research Reviews is to systematically review research on Spina bifida within different domains in an effort to promote integration and awareness of this research across disciplines involved directly with Spina bifida. In addition, we hope to increase the awareness of contemporary research and treatment strategies for researchers and practitioners involved with other developmental disabilities. Although some aspects of Spina bifida have been reviewed as part of previous issues, this is the first issue of the journal specifically devoted to Spina bifida since an issue on neural tube defects edited by Sells [1998].
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introduction Spina bifida a multidisciplinary perspective
Developmental Disabilities Research Reviews, 2010Co-Authors: Jack M Fletcher, Timothy J BreiAbstract:Spina bifida is the most common birth defect affecting the central nervous system (CNS) and is often characterized as the most complex birth defect compatible with survival [Liptak and El Samra, 2010]. Because of its complexity, the diagnosis and treatment of infants born with Spina bifida begins before birth and through adulthood, involving multiple disciplines. Not surprisingly, research has flourished across several domains over the past decade. The purpose of this special issue of Developmental Disabilities Research Reviews is to systematically review research on Spina bifida within different domains in an effort to promote integration and awareness of this research across disciplines involved directly with Spina bifida. In addition, we hope to increase the awareness of contemporary research and treatment strategies for researchers and practitioners involved with other developmental disabilities. Although some aspects of Spina bifida have been reviewed as part of previous issues, this is the first issue of the journal specifically devoted to Spina bifida since an issue on neural tube defects edited by Sells [1998].
