The Experts below are selected from a list of 1413 Experts worldwide ranked by ideXlab platform

Marco Costantini - One of the best experts on this subject based on the ideXlab platform.

  • co axial wet Spinning in 3d bioprinting state of the art and future perspective of microfluidic integration
    Biofabrication, 2018
    Co-Authors: Marco Costantini, Cristina Colosi, Wojciech świeszkowski, Andrea Barbetta
    Abstract:

    Nowadays, 3D bioprinting technologies are rapidly emerging in the field of tissue engineering and regenerative medicine as effective tools enabling the fabrication of advanced tissue constructs that can recapitulate in vitro organ/tissue functions. Selecting the best strategy for bioink deposition is often challenging and time consuming process, as bioink properties-in the first instance, rheological and gelation-strongly influence the suitable paradigms for its deposition. In this short review, we critically discuss one of the available approaches used for bioprinting-namely co-axial wet-Spinning Extrusion. Such a deposition system, in fact, demonstrated to be promising in terms of printing resolution, shape fidelity and versatility when compared to other methods. An overview of the performances of co-axial technology in the deposition of cellularized hydrogel fibres is discussed, highlighting its main features. Furthermore, we show how this approach allows (i) to decouple the printing accuracy from bioink rheological behaviour-thus notably simplifying the development of new bioinks-and (ii) to build heterogeneous multi-materials and/or multicellular constructs that can better mimic the native tissues when combined with microfluidic systems. Finally, the ongoing challenges and the future perspectives for the ultimate fabrication of functional constructs for advanced research studies are highlighted.

Andrea Barbetta - One of the best experts on this subject based on the ideXlab platform.

  • co axial wet Spinning in 3d bioprinting state of the art and future perspective of microfluidic integration
    Biofabrication, 2018
    Co-Authors: Marco Costantini, Cristina Colosi, Wojciech świeszkowski, Andrea Barbetta
    Abstract:

    Nowadays, 3D bioprinting technologies are rapidly emerging in the field of tissue engineering and regenerative medicine as effective tools enabling the fabrication of advanced tissue constructs that can recapitulate in vitro organ/tissue functions. Selecting the best strategy for bioink deposition is often challenging and time consuming process, as bioink properties-in the first instance, rheological and gelation-strongly influence the suitable paradigms for its deposition. In this short review, we critically discuss one of the available approaches used for bioprinting-namely co-axial wet-Spinning Extrusion. Such a deposition system, in fact, demonstrated to be promising in terms of printing resolution, shape fidelity and versatility when compared to other methods. An overview of the performances of co-axial technology in the deposition of cellularized hydrogel fibres is discussed, highlighting its main features. Furthermore, we show how this approach allows (i) to decouple the printing accuracy from bioink rheological behaviour-thus notably simplifying the development of new bioinks-and (ii) to build heterogeneous multi-materials and/or multicellular constructs that can better mimic the native tissues when combined with microfluidic systems. Finally, the ongoing challenges and the future perspectives for the ultimate fabrication of functional constructs for advanced research studies are highlighted.

Wojciech świeszkowski - One of the best experts on this subject based on the ideXlab platform.

  • co axial wet Spinning in 3d bioprinting state of the art and future perspective of microfluidic integration
    Biofabrication, 2018
    Co-Authors: Marco Costantini, Cristina Colosi, Wojciech świeszkowski, Andrea Barbetta
    Abstract:

    Nowadays, 3D bioprinting technologies are rapidly emerging in the field of tissue engineering and regenerative medicine as effective tools enabling the fabrication of advanced tissue constructs that can recapitulate in vitro organ/tissue functions. Selecting the best strategy for bioink deposition is often challenging and time consuming process, as bioink properties-in the first instance, rheological and gelation-strongly influence the suitable paradigms for its deposition. In this short review, we critically discuss one of the available approaches used for bioprinting-namely co-axial wet-Spinning Extrusion. Such a deposition system, in fact, demonstrated to be promising in terms of printing resolution, shape fidelity and versatility when compared to other methods. An overview of the performances of co-axial technology in the deposition of cellularized hydrogel fibres is discussed, highlighting its main features. Furthermore, we show how this approach allows (i) to decouple the printing accuracy from bioink rheological behaviour-thus notably simplifying the development of new bioinks-and (ii) to build heterogeneous multi-materials and/or multicellular constructs that can better mimic the native tissues when combined with microfluidic systems. Finally, the ongoing challenges and the future perspectives for the ultimate fabrication of functional constructs for advanced research studies are highlighted.

Cristina Colosi - One of the best experts on this subject based on the ideXlab platform.

  • co axial wet Spinning in 3d bioprinting state of the art and future perspective of microfluidic integration
    Biofabrication, 2018
    Co-Authors: Marco Costantini, Cristina Colosi, Wojciech świeszkowski, Andrea Barbetta
    Abstract:

    Nowadays, 3D bioprinting technologies are rapidly emerging in the field of tissue engineering and regenerative medicine as effective tools enabling the fabrication of advanced tissue constructs that can recapitulate in vitro organ/tissue functions. Selecting the best strategy for bioink deposition is often challenging and time consuming process, as bioink properties-in the first instance, rheological and gelation-strongly influence the suitable paradigms for its deposition. In this short review, we critically discuss one of the available approaches used for bioprinting-namely co-axial wet-Spinning Extrusion. Such a deposition system, in fact, demonstrated to be promising in terms of printing resolution, shape fidelity and versatility when compared to other methods. An overview of the performances of co-axial technology in the deposition of cellularized hydrogel fibres is discussed, highlighting its main features. Furthermore, we show how this approach allows (i) to decouple the printing accuracy from bioink rheological behaviour-thus notably simplifying the development of new bioinks-and (ii) to build heterogeneous multi-materials and/or multicellular constructs that can better mimic the native tissues when combined with microfluidic systems. Finally, the ongoing challenges and the future perspectives for the ultimate fabrication of functional constructs for advanced research studies are highlighted.

Josef Simonik - One of the best experts on this subject based on the ideXlab platform.

  • recycled pet nanocomposites improved by silanization of organoclays
    Journal of Applied Polymer Science, 2007
    Co-Authors: Milan Kracalik, Martin Studenovský, Jana Mikesova, Antonin Sikora, Ralf Thomann, Christian Friedrich, Ivan Fortelný, Josef Simonik
    Abstract:

    Recycled PET/organo-modified montmorillonite nanocomposites were prepared via melt compounding as a promising possibility of the used beverage bottles recovery. According to our previous work, the three suitable commercial organoclays Cloisite 25A, 10A, and 30B were additionally modified with [3-(glycidyloxy)propyl]trimethoxysilane, hexadecyltrimethoxysilane and (3-aminopropyl)trimethoxysilane. The selected organoclays were compounded in the concentration 5 wt % and their degree of intercalation/delamination was determined by wide-angle X-ray scattering and transmission electron microscopy. Modification of Cloisite 25A with [3-(glycidyloxy)propyl]trimethoxysilane increased homogeneity of silicate layers in recycled PET. Additional modification of Cloisite 10A and Cloisite 30B led to lower level of delamination concomitant with melt viscosity reduction. However, flow characteristics of all studied organoclay nanocomposites showed solid-like behavior at low frequencies. Silanization of commercial organoclays had remarkable impact on crystallinity and melt temperature decrease accompanied by faster formation of crystalline nuclei during injection molding. Thermogravimetric analysis showed enhancement of thermal stability of modified organoclays. The tensile tests confirmed significant increase of PET-R stiffness with organoclays loading and the system containing Cloisite 25A treated with [3-(glycidyloxy)propyl]trimethoxysilane revealed combination of high stiffness and extensibility, which could be utilized for production of high-performance materials by Spinning, Extrusion, and blow molding technologies. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2007