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G E Newman - One of the best experts on this subject based on the ideXlab platform.

  • bleeding gastric varices secondary to Splenic vein thrombosis successfully treated by Splenic artery embolization
    British Journal of Radiology, 1995
    Co-Authors: V G Mcdermott, R E England, G E Newman
    Abstract:

    Abstract Splenic vein thrombosis is a complication of pancreatic carcinoma or pancreatitis. It may lead to gastric varices which are difficult to treat and splenectomy may be required to stop variceal bleeding. A case of bleeding gastric varices secondary to Splenic vein thrombosis and successfully treated by Splenic artery embolization is reported. Embolization was performed by transcatheter deposition of four Gianturco coils into the Splenic artery. This resulted in reduced blood flow through the spleen with partial Splenic Infarction and cessation of variceal bleeding. There has been no recurrence of bleeding in the 6 months since the procedure. Literature review confirms that experience of using this treatment is very limited and it should therefore be restricted to patients at high risk from surgery.

  • case report bleeding gastric varices secondary to Splenic vein thrombosis successfully treated by Splenic artery embolization
    British Journal of Radiology, 1995
    Co-Authors: V G Mcdermott, R E England, G E Newman
    Abstract:

    Splenic vein thrombosis is a complication of pancreatic carcinoma or pancreatitis. It may lead to gastric varices which are difficult to treat and splenectomy may be required to stop variceal bleeding. A case of bleeding gastric varices secondary to Splenic vein thrombosis and successfully treated by Splenic artery embolization is reported. Embolization was performed by transcatheter deposition of four Gianturco coils into the Splenic artery. This resulted in reduced blood flow through the spleen with partial Splenic Infarction and cessation of variceal bleeding. There has been no recurrence of bleeding in the 6 months since the procedure. Literature review confirms that experience of using this treatment is very limited and it should therefore be restricted to patients at high risk from surgery.

George M Abraham - One of the best experts on this subject based on the ideXlab platform.

V G Mcdermott - One of the best experts on this subject based on the ideXlab platform.

  • bleeding gastric varices secondary to Splenic vein thrombosis successfully treated by Splenic artery embolization
    British Journal of Radiology, 1995
    Co-Authors: V G Mcdermott, R E England, G E Newman
    Abstract:

    Abstract Splenic vein thrombosis is a complication of pancreatic carcinoma or pancreatitis. It may lead to gastric varices which are difficult to treat and splenectomy may be required to stop variceal bleeding. A case of bleeding gastric varices secondary to Splenic vein thrombosis and successfully treated by Splenic artery embolization is reported. Embolization was performed by transcatheter deposition of four Gianturco coils into the Splenic artery. This resulted in reduced blood flow through the spleen with partial Splenic Infarction and cessation of variceal bleeding. There has been no recurrence of bleeding in the 6 months since the procedure. Literature review confirms that experience of using this treatment is very limited and it should therefore be restricted to patients at high risk from surgery.

  • case report bleeding gastric varices secondary to Splenic vein thrombosis successfully treated by Splenic artery embolization
    British Journal of Radiology, 1995
    Co-Authors: V G Mcdermott, R E England, G E Newman
    Abstract:

    Splenic vein thrombosis is a complication of pancreatic carcinoma or pancreatitis. It may lead to gastric varices which are difficult to treat and splenectomy may be required to stop variceal bleeding. A case of bleeding gastric varices secondary to Splenic vein thrombosis and successfully treated by Splenic artery embolization is reported. Embolization was performed by transcatheter deposition of four Gianturco coils into the Splenic artery. This resulted in reduced blood flow through the spleen with partial Splenic Infarction and cessation of variceal bleeding. There has been no recurrence of bleeding in the 6 months since the procedure. Literature review confirms that experience of using this treatment is very limited and it should therefore be restricted to patients at high risk from surgery.

George R Buchanan - One of the best experts on this subject based on the ideXlab platform.

  • acute Splenic complications in children with sickle cell hemoglobin c disease
    The Journal of Pediatrics, 1997
    Co-Authors: Victor M. Aquino, J. M. Norvell, George R Buchanan
    Abstract:

    OBJECTIVE: To determine the frequency and severity of acute Splenic complications in children and adolescents with sickle cell (SC) hemoglobin C disease. METHODS: The medical records of 271 patients with SC disease seen at our center were reviewed to evaluate the incidence and severity of acute complications involving the spleen. RESULTS: Sixteen (6%) children had acute Splenic complications. Thirteen (5%) had 16 episodes of acute Splenic sequestration (ASSC), with the initial event occurring at a mean age of 8.9 years (range, 2 to 17 years). Splenomegaly had been noted before the initial event in 6 (46%) of the 13 cases, and 3 (23%) had a history of painful Splenic Infarction. Two young children (aged 4 and 6 years) had a hemoglobin value less than 2 gm/dl, one without history of Splenic enlargement. Three (23%) children had a second episode of ASSC. Three additional patients had a history of acute painful Splenic Infarction, two of whom also had Splenic hemorrhage. Eight (3%) of the 271 children required splenectomy (1 after the initial episode of ASSC, 3 after a second episode of ASSC, 2 as a result of pain accompanying chronic Infarction and ASSC, and 2 because of Splenic hemorrhage). No deaths resulted from ASSC. CONCLUSIONS: We conclude that (1) acute Splenic complications in children and adolescents with SC disease are relatively uncommon, (2) most episodes of ASSC occur in preadolescents, (3) ASSC can be life threatening, even in younger children, and (4) prior splenomegaly is not a good predictor of ASSC. Thus it is vital that the parents of all children with SC disease be instructed to palpate their child's spleen regularly.

  • acute Splenic complications in children with sickle cell hemoglobin c disease
    The Journal of Pediatrics, 1997
    Co-Authors: Victor M. Aquino, J. M. Norvell, George R Buchanan
    Abstract:

    Abstract Objective: To determine the frequency and severity of acute Splenic complications in children and adolescents with sickle cell (SC) hemoglobin C disease. Methods: The medical records of 271 patients with SC disease seen at our center were reviewed to evaluate the incidence and severity of acute complications involving the spleen. Results: Sixteen (6%) children had acute Splenic complications. Thirteen (5%) had 16 episodes of acute Splenic sequestration (ASSC), with the initial event occurring at a mean age of 8.9 years (range, 2 to 17 years). Splenomegaly had been noted before the initial event in 6 (46%) of the 13 cases, and 3 (23%) had a history of painful Splenic Infarction. Two young children (aged 4 and 6 years) had a hemoglobin value less than 2 gm/dl, one without history of Splenic enlargement. Three (23%) children had a second episode of ASSC. Three additional patients had a history of acute painful Splenic Infarction, two of whom also had Splenic hemorrhage. Eight (3%) of the 271 children required splenectomy (1 after the initial episode of ASSC, 3 after a second episode of ASSC, 2 as a result of pain accompanying chronic Infarction and ASSC, and 2 because of Splenic hemorrhage). No deaths resulted from ASSC. Conclusions: We conclude that (1) acute Splenic complications in children and adolescents with SC disease are relatively uncommon, (2) most episodes of ASSC occur in preadolescents, (3) ASSC can be life threatening, even in younger children, and (4) prior splenomegaly is not a good predictor of ASSC. Thus it is vital that the parents of all children with SC disease be instructed to palpate their child's spleen regularly. (J Pediart 1997;130:961-5)

Tobias Tenenbaum - One of the best experts on this subject based on the ideXlab platform.

  • Splenic Infarction in a patient hereditary spherocytosis protein c deficiency and acute infectious mononucleosis
    European Journal of Pediatrics, 2008
    Co-Authors: Christian Breuer, G Janssen, H J Laws, J Schaper, Ertan Mayatepek, Horst Schroten, Tobias Tenenbaum
    Abstract:

    Splenic Infarction is a common cause of left upper quadrant pain and must be suspected in patients with hematologic or thromboembolic conditions and signs of localized or systemic inflammation. Although several mechanisms have been proposed for Splenic Infarction in patients with various hematologic disorders, hereditary spherocytosis (HS) is usually not associated with an increased risk for thromboembolic events. We report a 13-year-old male with HS who was referred to our hospital with a 4-day history of fever and left upper quadrant pain. Ultrasound scans and magnetic resonance imaging showed lesions suggestive of Splenic Infarction. Initially, antibiotic treatment was started because secondary infection was suspected. However, 1 week after admission the patient developed typical clinical signs of acute infectious mononucleosis. Further laboratory work up confirmed the diagnosis of acute Epstein-Barr virus infection and additionally revealed protein C deficiency. This association has not been reported previously and may have contributed to the development of Splenic Infarction. Since infectious mononucleosis is a common cause for clinical consultations in adolescence, physicians caring for children with hematologic disorders should be particularly aware of those possible complications.