The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform
V Vidal - One of the best experts on this subject based on the ideXlab platform.
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the presence of Spontaneous Portosystemic Shunts increases the risk of complications after transjugular intrahepatic Portosystemic Shunt tips placement
Diagnostic and interventional imaging, 2016Co-Authors: Patrick Borentain, J Soussan, N Resseguier, D Bottafridlund, Jeancharles Dufour, Rene Gerolami, V VidalAbstract:Purpose: The goal of this study was to identify clinical and imaging ă variables that are associated with an unfavorable outcome during the 30 ă days following transjugular intrahepatic Portosystemic Shunt (TIPS) ă placement. ă Material and methods: Fifty-four consecutive patients with liver ă cirrhosis (Child-Pugh 6-13, Model for End-stage Liver Disease 7-26) ă underwent TIPS placement for refractory ascites (n = 25), recurrent or ă uncontrolled variceal bleeding (n = 23) or both (n = 6). Clinical, ă biological and imaging variables including type of stent (covered n = ă 40; bare-stent n = 14), presence of Spontaneous Portosystemic Shunt (n = ă 31), and variations in Portosystemic pressure gradient were recorded. ă Early severe complication was defined as the occurrence of overt hepatic ă encephalopathy or death within the 30 days following TIPS placement. ă Results: Sixteen patients (30%) presented with early severe ă complication after TIPS placement. Child-Pugh score was independently ă associated with complication (HR = 1.52, P < 0.001). Among the imaging ă variables, opacification of Spontaneous Portosystemic Shunt during TIPS ă placement but before its creation was associated with an increased risk ă of early complication (P = 0.04). The other imaging variables were not ă associated with occurrence of complication. ă Conclusion: Identification of Spontaneous Portosystemic Shunt during ă TIPS placement reflects the presence of varices and is associated with ă an increased risk of early severe complication. (C) 2016 Editions ă francaises de radiologie. Published by Elsevier Masson SAS. All rights ă reserved.
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the presence of Spontaneous Portosystemic Shunts increases the risk of ă complications after transjugular intrahepatic Portosystemic Shunt tips ă placement
Research Papers in Economics, 2016Co-Authors: Patrick Borentain, J Soussan, N Resseguier, D Bottafridlund, Rene Gerolami, J C Dufourd, V VidalAbstract:Purpose: The goal of this study was to identify clinical and imaging ă variables that are associated with an unfavorable outcome during the 30 ă days following transjugular intrahepatic Portosystemic Shunt (TIPS) ă placement. ă Material and methods: Fifty-four consecutive patients with liver ă cirrhosis (Child-Pugh 6-13, Model for End-stage Liver Disease 7-26) ă underwent TIPS placement for refractory ascites (n = 25), recurrent or ă uncontrolled variceal bleeding (n = 23) or both (n = 6). Clinical, ă biological and imaging variables including type of stent (covered n = ă 40; bare-stent n = 14), presence of Spontaneous Portosystemic Shunt (n = ă 31), and variations in Portosystemic pressure gradient were recorded. ă Early severe complication was defined as the occurrence of overt hepatic ă encephalopathy or death within the 30 days following TIPS placement. ă Results: Sixteen patients (30%) presented with early severe ă complication after TIPS placement. Child-Pugh score was independently ă associated with complication (HR = 1.52, P
Yuzheng Zhuge - One of the best experts on this subject based on the ideXlab platform.
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Comparison of transjugular intrahepatic Portosystemic Shunt for treatment of variceal bleeding in patients with cirrhosis with or without Spontaneous Portosystemic Shunt.
European journal of gastroenterology & hepatology, 2019Co-Authors: Xiafei Leng, Feng Zhang, Ming Zhang, Huiwen Guo, Xiaochun Yin, Jiangqiang Xiao, Yi Wang, Xiaoping Zou, Yuzheng ZhugeAbstract:BACKGROUND AND AIMS Transjugular intrahepatic Portosystemic Shunt (TIPS) is an effective intervention for portal hypertensive complications in cirrhosis. Spontaneous Portosystemic Shunts (SPSSs) may increase the risk of post-TIPS complications and mortality. This study was done to evaluate the safety and efficacy of TIPS for treating variceal bleeding between patients with and without SPSSs. PATIENTS AND METHODS The clinical data of 467 consecutive patients with cirrhosis who received TIPS for variceal bleeding from January 2012 to January 2018 were screened. A total of 33 patients with coexisting SPSSs were included as the SPSS group, and 33 patients without SPSSs were randomly selected as control. The procedure-related complications and long-term outcomes were compared between the two groups. RESULTS Both groups were successfully treated with TIPS. SPSSs were antegradely embolized before TIPS placement. In terms of safety, one patient in the SPSS group experienced an asymptomatic pulmonary embolism, and another patient experienced serious gastric ulcer bleeding. Overall, 23 (70.0%) patients in the SPSS group and 16 (51.5%) patients in the control group experienced different mild complications (P=0.131). During a median follow-up of more than 2 years, the rebleeding rates (7.1 vs. 3.7% at 1 year, P=0.508), overt hepatic encephalopathy occurrence rates (34.4 vs. 39.4% at 2 years, P=0.685), and orthotopic liver transplantation-free survival rates (73.2 vs. 70.7% at 2 years, P=0.557) were not significantly different between the two groups. CONCLUSION TIPS combined with antegrade embolization is safe, effective, and feasible for patients with SPSSs, with safety and long-term outcomes comparable to patients without SPSSs.
Xiaozhong Guo - One of the best experts on this subject based on the ideXlab platform.
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a large Spontaneous extrahepatic Portosystemic Shunt in a cirrhotic patient from main portal vein to right renal vein
AME Medical Journal, 2017Co-Authors: Yongxin Bao, Xiaodong Shao, Xiaozhong GuoAbstract:In this paper, we illustrated a very rare type of Spontaneous Portosystemic Shunt originating from main portal vein to right renal vein in a cirrhotic patient. The diagnosis of such a large Spontaneous Portosystemic Shunt was established according to the axial contrast-enhanced computed tomography scans. The cause and outcome were also discussed.
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A large Spontaneous intrahepatic Portosystemic Shunt in a cirrhotic patient.
Intractable & rare diseases research, 2016Co-Authors: Yue Hou, Xiaozhong GuoAbstract:A Spontaneous Portosystemic Shunt is a rare malformation of the vessels supplying the liver. This condition often leads to the development of hepatic encephalopathy due to excessive Shunting of blood from the portal vein to the inferior vena cava. Some studies have suggested that the presence of Spontaneous Portosystemic Shunts is inversely associated with the appearance of large esophageal varices. Spontaneous intrahepatic Portosystemic Shunts (SIPSS) are far less frequently observed than extrahepatic Portosystemic Shunts, which include spleno-gastric-renal Shunts, mesenteric-caval Shunts, and a large patent umbilical vein. Reported here is a case of decompensated liver cirrhosis with a large SIPSS without any incidence of overt hepatic encephalopathy.
Patrick Borentain - One of the best experts on this subject based on the ideXlab platform.
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the presence of Spontaneous Portosystemic Shunts increases the risk of complications after transjugular intrahepatic Portosystemic Shunt tips placement
Diagnostic and interventional imaging, 2016Co-Authors: Patrick Borentain, J Soussan, N Resseguier, D Bottafridlund, Jeancharles Dufour, Rene Gerolami, V VidalAbstract:Purpose: The goal of this study was to identify clinical and imaging ă variables that are associated with an unfavorable outcome during the 30 ă days following transjugular intrahepatic Portosystemic Shunt (TIPS) ă placement. ă Material and methods: Fifty-four consecutive patients with liver ă cirrhosis (Child-Pugh 6-13, Model for End-stage Liver Disease 7-26) ă underwent TIPS placement for refractory ascites (n = 25), recurrent or ă uncontrolled variceal bleeding (n = 23) or both (n = 6). Clinical, ă biological and imaging variables including type of stent (covered n = ă 40; bare-stent n = 14), presence of Spontaneous Portosystemic Shunt (n = ă 31), and variations in Portosystemic pressure gradient were recorded. ă Early severe complication was defined as the occurrence of overt hepatic ă encephalopathy or death within the 30 days following TIPS placement. ă Results: Sixteen patients (30%) presented with early severe ă complication after TIPS placement. Child-Pugh score was independently ă associated with complication (HR = 1.52, P < 0.001). Among the imaging ă variables, opacification of Spontaneous Portosystemic Shunt during TIPS ă placement but before its creation was associated with an increased risk ă of early complication (P = 0.04). The other imaging variables were not ă associated with occurrence of complication. ă Conclusion: Identification of Spontaneous Portosystemic Shunt during ă TIPS placement reflects the presence of varices and is associated with ă an increased risk of early severe complication. (C) 2016 Editions ă francaises de radiologie. Published by Elsevier Masson SAS. All rights ă reserved.
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the presence of Spontaneous Portosystemic Shunts increases the risk of ă complications after transjugular intrahepatic Portosystemic Shunt tips ă placement
Research Papers in Economics, 2016Co-Authors: Patrick Borentain, J Soussan, N Resseguier, D Bottafridlund, Rene Gerolami, J C Dufourd, V VidalAbstract:Purpose: The goal of this study was to identify clinical and imaging ă variables that are associated with an unfavorable outcome during the 30 ă days following transjugular intrahepatic Portosystemic Shunt (TIPS) ă placement. ă Material and methods: Fifty-four consecutive patients with liver ă cirrhosis (Child-Pugh 6-13, Model for End-stage Liver Disease 7-26) ă underwent TIPS placement for refractory ascites (n = 25), recurrent or ă uncontrolled variceal bleeding (n = 23) or both (n = 6). Clinical, ă biological and imaging variables including type of stent (covered n = ă 40; bare-stent n = 14), presence of Spontaneous Portosystemic Shunt (n = ă 31), and variations in Portosystemic pressure gradient were recorded. ă Early severe complication was defined as the occurrence of overt hepatic ă encephalopathy or death within the 30 days following TIPS placement. ă Results: Sixteen patients (30%) presented with early severe ă complication after TIPS placement. Child-Pugh score was independently ă associated with complication (HR = 1.52, P
Xiafei Leng - One of the best experts on this subject based on the ideXlab platform.
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Comparison of transjugular intrahepatic Portosystemic Shunt for treatment of variceal bleeding in patients with cirrhosis with or without Spontaneous Portosystemic Shunt.
European journal of gastroenterology & hepatology, 2019Co-Authors: Xiafei Leng, Feng Zhang, Ming Zhang, Huiwen Guo, Xiaochun Yin, Jiangqiang Xiao, Yi Wang, Xiaoping Zou, Yuzheng ZhugeAbstract:BACKGROUND AND AIMS Transjugular intrahepatic Portosystemic Shunt (TIPS) is an effective intervention for portal hypertensive complications in cirrhosis. Spontaneous Portosystemic Shunts (SPSSs) may increase the risk of post-TIPS complications and mortality. This study was done to evaluate the safety and efficacy of TIPS for treating variceal bleeding between patients with and without SPSSs. PATIENTS AND METHODS The clinical data of 467 consecutive patients with cirrhosis who received TIPS for variceal bleeding from January 2012 to January 2018 were screened. A total of 33 patients with coexisting SPSSs were included as the SPSS group, and 33 patients without SPSSs were randomly selected as control. The procedure-related complications and long-term outcomes were compared between the two groups. RESULTS Both groups were successfully treated with TIPS. SPSSs were antegradely embolized before TIPS placement. In terms of safety, one patient in the SPSS group experienced an asymptomatic pulmonary embolism, and another patient experienced serious gastric ulcer bleeding. Overall, 23 (70.0%) patients in the SPSS group and 16 (51.5%) patients in the control group experienced different mild complications (P=0.131). During a median follow-up of more than 2 years, the rebleeding rates (7.1 vs. 3.7% at 1 year, P=0.508), overt hepatic encephalopathy occurrence rates (34.4 vs. 39.4% at 2 years, P=0.685), and orthotopic liver transplantation-free survival rates (73.2 vs. 70.7% at 2 years, P=0.557) were not significantly different between the two groups. CONCLUSION TIPS combined with antegrade embolization is safe, effective, and feasible for patients with SPSSs, with safety and long-term outcomes comparable to patients without SPSSs.