The Experts below are selected from a list of 237 Experts worldwide ranked by ideXlab platform
Rodrigo De Almeida Paes - One of the best experts on this subject based on the ideXlab platform.
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Sporothrix schenckii and sporotrichosis
Clinical Microbiology Reviews, 2011Co-Authors: Monica Bastos De Lima Barros, Rodrigo De Almeida Paes, Armando De Oliveira SchubachAbstract:Sporotrichosis, which is caused by the dimorphic fungus Sporothrix schenckii, is currently distributed throughout the world, especially in tropical and subtropical zones. Infection generally occurs by traumatic inoculation of soil, plants, and organic matter contaminated with the fungus. Certain leisure and occupational activities, such as floriculture, agriculture, mining, and wood exploitation, are traditionally associated with the mycosis. Zoonotic transmission has been described in isolated cases or in small outbreaks. Since the end of the 1990s there has been an epidemic of sporotrichosis associated with transmission by cats in Rio de Janeiro, Brazil. More than 2,000 human cases and 3,000 animal cases have been reported. In humans, the lesions are usually restricted to the skin, subcutaneous cellular tissue, and adjacent lymphatic vessels. In cats, the disease can evolve with severe clinical manifestations and frequent systemic involvement. The gold standard for sporotrichosis diagnosis is culture. However, serological, histopathological, and molecular approaches have been recently adopted as auxiliary tools for the diagnosis of this mycotic infection. The first-choice treatment for both humans and cats is itraconazole.
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Sporothrix schenckii meningitis in aids during immune reconstitution syndrome
Journal of Neurology Neurosurgery and Psychiatry, 2010Co-Authors: Maria Clara Gutierrez Galhardo, Rodrigo De Almeida Paes, Marcus Tulius T Silva, Marco A Lima, Estevao Portela Nunes, Luiz Eduardo C Schettini, Rodrigo Fernandes De Freitas, Elizabeth De Sousa Neves, Antonio Carlos Francesconi Do ValleAbstract:Sporotrichosis is a fungal disease usually restricted to the cutaneous and lymphatic systems. Visceral involvement is unusual. To date, only 21 cases of sporotrichosis meningitis have been reported, some of these associated with immunosuppression. According to the reported cases, difficulty establishing the correct diagnosis is almost the rule which, undoubtedly, is associated with a worse prognosis. In this report, two HIV infected patients are described who developed meningitis due to Sporothrix schenckii associated with immune reconstitution inflammatory syndrome. This is the first report of sporotrichosis meningitis associated with immune reconstitution inflammatory syndrome in AIDS patients.
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in vitro antifungal susceptibilities of Sporothrix schenckii in two growth phases
Antimicrobial Agents and Chemotherapy, 2005Co-Authors: Luciana Trilles, Rodrigo De Almeida Paes, Belkys Fernandeztorres, Marcia Dos Santos Lazera, Bodo Wanke, Armando De Oliveira Schubach, Isabel Inza, Josep GuarroAbstract:We have determined the antifungal susceptibilities of 34 clinical isolates of the dimorphic fungus Sporothrix schenckii to 11 drugs using a microdilution method. In general, the type of growth phase (mycelial or yeast) and the temperature of incubation (30 or 35°C) exerted a significant influence on the MICs.
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Utilidade do coágulo sangüíneo para o isolamento de Sporothrix schenckii de gatos naturalmente infectados Sporothrix schenckii isolation from blood clot of naturally infected cats
2004Co-Authors: Tânia Maria Valente Pacheco, Sandro Antonio Pereira, Armando De Oliveira, Thais Okamoto, Fabiano Borges Figueiredo, Luiz Rodrigo, Paes Leme, Rodrigo De Almeida Paes, Mauro Célio De Almeida, Antônio CarlosAbstract:Abstract The diagnosis of disseminated sporotrichosis is usually obtained by necropsyand the isolation of Sporothrix schenckii from blood is rare. Fungemia wasshown in vivo through the isolation of S. schenckii from peripheral blood of 13(n=38, 34.2%) cats with naturally acquired sporotrichosis. The coinfection withFIV and with FeLV found, respectively, in 6 (n=34, 17.6%) cases and 1 (n=34,2.9%), apparently did not alter the frequency of the isolation of S. schenckii fromperipheral blood. There was agreement of 84.2% comparing these results to theblood culture results simultaneously achieved. In this way, we propose the clotculture as a practical alternative method, efficient and cheap for the diagnosis ofdisseminated sporotrichosis in cats in vivo . Key-words: SISSporothrix schenckii.Lood culture.Clot.Cat. Referencias 1.MORGAN, M. A.; COCKERILL, F. R. D.; CORTESE,D. A.; ROBERTS, G. D. Disseminated sporotrichosiswith Sporothrix schenckii fungemia. DiagnosticMicrobiology Infectious Disease
Armando De Oliveira Schubach - One of the best experts on this subject based on the ideXlab platform.
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Sporothrix schenckii and sporotrichosis
Clinical Microbiology Reviews, 2011Co-Authors: Monica Bastos De Lima Barros, Rodrigo De Almeida Paes, Armando De Oliveira SchubachAbstract:Sporotrichosis, which is caused by the dimorphic fungus Sporothrix schenckii, is currently distributed throughout the world, especially in tropical and subtropical zones. Infection generally occurs by traumatic inoculation of soil, plants, and organic matter contaminated with the fungus. Certain leisure and occupational activities, such as floriculture, agriculture, mining, and wood exploitation, are traditionally associated with the mycosis. Zoonotic transmission has been described in isolated cases or in small outbreaks. Since the end of the 1990s there has been an epidemic of sporotrichosis associated with transmission by cats in Rio de Janeiro, Brazil. More than 2,000 human cases and 3,000 animal cases have been reported. In humans, the lesions are usually restricted to the skin, subcutaneous cellular tissue, and adjacent lymphatic vessels. In cats, the disease can evolve with severe clinical manifestations and frequent systemic involvement. The gold standard for sporotrichosis diagnosis is culture. However, serological, histopathological, and molecular approaches have been recently adopted as auxiliary tools for the diagnosis of this mycotic infection. The first-choice treatment for both humans and cats is itraconazole.
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in vitro antifungal susceptibilities of Sporothrix schenckii in two growth phases
Antimicrobial Agents and Chemotherapy, 2005Co-Authors: Luciana Trilles, Rodrigo De Almeida Paes, Belkys Fernandeztorres, Marcia Dos Santos Lazera, Bodo Wanke, Armando De Oliveira Schubach, Isabel Inza, Josep GuarroAbstract:We have determined the antifungal susceptibilities of 34 clinical isolates of the dimorphic fungus Sporothrix schenckii to 11 drugs using a microdilution method. In general, the type of growth phase (mycelial or yeast) and the temperature of incubation (30 or 35°C) exerted a significant influence on the MICs.
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isolation of Sporothrix schenckii from the nails of domestic cats felis catus
Medical Mycology, 2001Co-Authors: Tânia Maria Pacheco Schubach, Antonio Carlos Francesconi Do Valle, Maria Clara Gutierrezgalhardo, Paulo Cezar Fialho Monteiro, R S Reis, Rosely Maria Zancopeoliveira, Keyla Belizia Feldman Marzochi, Armando De Oliveira SchubachAbstract:We report the first isolation of Sporothrix schenckii from the nail surfaces of cats. The fungus grew from nail clippings of three cats associated with three household outbreaks of sporotrichosis involving cats and human beings. The identification of the isolates was based on macroscopic and microscopic morphological characteristics at 25 °C and conversion of S. schenckii to the yeast-like form at 37 °C.
Josep Guarro - One of the best experts on this subject based on the ideXlab platform.
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molecular phylogeny of Sporothrix schenckii
Journal of Clinical Microbiology, 2006Co-Authors: Rita Marimon, Luciana Trilles, Marcia Dos Santos Lazera, Josepa Gene, Josep Cano, Josep GuarroAbstract:The pathogenic dimorphic fungus Sporothrix schenckii is the agent responsible for sporotrichosis, an important fungal infection with a worldwide distribution. Little is known about the population structure of S. schenckii, although recent molecular and phenotypic data seem to demonstrate that different genetic lineages exist within this species. The aim of this study was to determine, by sequence analysis of three protein coding loci (chitin synthase, beta-tubulin, and calmodulin), whether this variability is due to species divergence or intraspecific diversity in S. schenckii. We included in the analysis 60 isolates (59 of clinical and 1 of environmental origin) of this species from a wide geographical range. DNA sequence data from the three nuclear regions were used in a phylogenetic analysis. The combined analysis of the three loci revealed the presence of three major clades, one grouping all of the European isolates, another with only Brazilian isolates, and the third with isolates from other South American countries and Africa. A total of 14 100% bootstrap-supported nodes were shown, 6 of them representing putative phylogenetic species. Our data also demonstrated that most of these species prevail in different geographical regions.
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in vitro antifungal susceptibilities of Sporothrix schenckii in two growth phases
Antimicrobial Agents and Chemotherapy, 2005Co-Authors: Luciana Trilles, Rodrigo De Almeida Paes, Belkys Fernandeztorres, Marcia Dos Santos Lazera, Bodo Wanke, Armando De Oliveira Schubach, Isabel Inza, Josep GuarroAbstract:We have determined the antifungal susceptibilities of 34 clinical isolates of the dimorphic fungus Sporothrix schenckii to 11 drugs using a microdilution method. In general, the type of growth phase (mycelial or yeast) and the temperature of incubation (30 or 35°C) exerted a significant influence on the MICs.
Antonio Carlos Francesconi Do Valle - One of the best experts on this subject based on the ideXlab platform.
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Sporothrix schenckii meningitis in aids during immune reconstitution syndrome
Journal of Neurology Neurosurgery and Psychiatry, 2010Co-Authors: Maria Clara Gutierrez Galhardo, Rodrigo De Almeida Paes, Marcus Tulius T Silva, Marco A Lima, Estevao Portela Nunes, Luiz Eduardo C Schettini, Rodrigo Fernandes De Freitas, Elizabeth De Sousa Neves, Antonio Carlos Francesconi Do ValleAbstract:Sporotrichosis is a fungal disease usually restricted to the cutaneous and lymphatic systems. Visceral involvement is unusual. To date, only 21 cases of sporotrichosis meningitis have been reported, some of these associated with immunosuppression. According to the reported cases, difficulty establishing the correct diagnosis is almost the rule which, undoubtedly, is associated with a worse prognosis. In this report, two HIV infected patients are described who developed meningitis due to Sporothrix schenckii associated with immune reconstitution inflammatory syndrome. This is the first report of sporotrichosis meningitis associated with immune reconstitution inflammatory syndrome in AIDS patients.
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isolation of Sporothrix schenckii from the nails of domestic cats felis catus
Medical Mycology, 2001Co-Authors: Tânia Maria Pacheco Schubach, Antonio Carlos Francesconi Do Valle, Maria Clara Gutierrezgalhardo, Paulo Cezar Fialho Monteiro, R S Reis, Rosely Maria Zancopeoliveira, Keyla Belizia Feldman Marzochi, Armando De Oliveira SchubachAbstract:We report the first isolation of Sporothrix schenckii from the nail surfaces of cats. The fungus grew from nail clippings of three cats associated with three household outbreaks of sporotrichosis involving cats and human beings. The identification of the isolates was based on macroscopic and microscopic morphological characteristics at 25 °C and conversion of S. schenckii to the yeast-like form at 37 °C.
A Wreiole - One of the best experts on this subject based on the ideXlab platform.
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Sporothrix schenckii fungemia without disseminated sporotrichosis.
Journal of clinical microbiology, 1992Co-Authors: R M Kosinski, P Axelrod, John H. Rex, M Burday, R Sivaprasad, A WreioleAbstract:Fungemia is a rare complication of Sporothrix schenckii infection and has always been associated with disseminated sporotrichosis. We describe an immunocompetent patient with localized lymphocutaneous sporotrichosis from whose blood the fungus was isolated. A lysis-centrifugation blood culture system may have improved our ability to detect low-level S. schenckii fungemia.