The Experts below are selected from a list of 11742 Experts worldwide ranked by ideXlab platform
Yoshihiro Kakeji - One of the best experts on this subject based on the ideXlab platform.
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two Stage Operation for high risk patients with thoracic esophageal cancer an old Operation revisited
Annals of Surgical Oncology, 2011Co-Authors: Masaru Morita, Hiroshi Saeki, Tomonori Nakanoko, Nobuhide Kubo, Yoshihiko Fujinaka, Keisuke Ikeda, Akinori Egashira, Hideaki Uchiyama, Takefumi Ohga, Yoshihiro KakejiAbstract:PURPOSE: An esophagectomy followed by reconstruction for esophageal cancer is a highly aggressive Operation. The purpose of this study was to justify a two-Stage Operation for high-risk patients with esophageal cancer. METHODS: The clinical results of 27 patients who underwent two-Stage Operation were compared with 118 patients who underwent a simultaneous resection and reconstruction (control subjects). The reasons for the selection of the two-Stage Operation were underlying general disease in 13 patients (liver dysfunction, n = 6; pulmonary disease, n = 3; poor performance status, n = 2; diabetes and renal failure, n = 1 each) and high-risk Operation in 14 other patients (colon interposition, n = 7; salvage Operation after definitive chemoradiotherapy, n = 4; and intraoperative events, n = 3). The patients initially underwent an esophagectomy and a cervical esophagostomy. Reconstruction was usually performed 2-3 weeks later. RESULTS: The patients in the two-Stage group were older than the control patients (mean 67.8 vs. 61.6 years old). The morbidity rate of the two-Stage Operation was 29.6%, which was not statistically different than control patients (32.2%). Postoperative complications in the two-Stage Operation were anastomotic leakage in 5 patients, and pneumonia and wound infection in 1 patient each. No patient experienced in-hospital death. The survival rates were not statistically different between the two groups. CONCLUSION: A two-Stage Operation is a safe Operation that prevents the occurrence of critical postoperative complications, and it thus may be considered an important treatment strategy for high-risk patients with esophageal cancer.
Masaru Morita - One of the best experts on this subject based on the ideXlab platform.
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two Stage Operation for high risk patients with thoracic esophageal cancer an old Operation revisited
Annals of Surgical Oncology, 2011Co-Authors: Masaru Morita, Hiroshi Saeki, Tomonori Nakanoko, Nobuhide Kubo, Yoshihiko Fujinaka, Keisuke Ikeda, Akinori Egashira, Hideaki Uchiyama, Takefumi Ohga, Yoshihiro KakejiAbstract:PURPOSE: An esophagectomy followed by reconstruction for esophageal cancer is a highly aggressive Operation. The purpose of this study was to justify a two-Stage Operation for high-risk patients with esophageal cancer. METHODS: The clinical results of 27 patients who underwent two-Stage Operation were compared with 118 patients who underwent a simultaneous resection and reconstruction (control subjects). The reasons for the selection of the two-Stage Operation were underlying general disease in 13 patients (liver dysfunction, n = 6; pulmonary disease, n = 3; poor performance status, n = 2; diabetes and renal failure, n = 1 each) and high-risk Operation in 14 other patients (colon interposition, n = 7; salvage Operation after definitive chemoradiotherapy, n = 4; and intraoperative events, n = 3). The patients initially underwent an esophagectomy and a cervical esophagostomy. Reconstruction was usually performed 2-3 weeks later. RESULTS: The patients in the two-Stage group were older than the control patients (mean 67.8 vs. 61.6 years old). The morbidity rate of the two-Stage Operation was 29.6%, which was not statistically different than control patients (32.2%). Postoperative complications in the two-Stage Operation were anastomotic leakage in 5 patients, and pneumonia and wound infection in 1 patient each. No patient experienced in-hospital death. The survival rates were not statistically different between the two groups. CONCLUSION: A two-Stage Operation is a safe Operation that prevents the occurrence of critical postoperative complications, and it thus may be considered an important treatment strategy for high-risk patients with esophageal cancer.
Michael Ka Wah Li - One of the best experts on this subject based on the ideXlab platform.
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endolaparoscopic approach vs conventional open surgery in the treatment of obstructing left sided colon cancer a randomized controlled trial
Archives of Surgery, 2009Co-Authors: Hester Yui Shan Cheung, Chi Chiu Chung, W W C Tsang, James C H Wong, Michael Ka Wah LiAbstract:Objective To compare self-expanding metal stents with emergency open surgery in the treatment of obstructing left-sided colon cancer. Design A randomized controlled trial. Setting An acute care hospital. Patients Adult patients with an obstructing tumor between the splenic flexure and rectosigmoid junction. Main Outcome Measures Successful 1-Stage Operation, cumulative operative time, blood loss, hospital stay, pain score, and postoperative complications. Results Forty-eight patients were analyzed. Twenty-four underwent endoluminal stenting followed by laparoscopic resection and 24 underwent emergency open surgery. The 2 groups were matched for age, sex, body mass index, and disease staging. Patients in the endolaparoscopic group had significantly less cumulative blood loss and lower pain, incidence of anastomotic leak, and wound infection. Significantly more patients in the endolaparoscopic group had a successful 1-Stage Operation performed (16 vs 9, P = .04). None of the patients in the endolaparoscopic group had a permanent stoma compared with 6 patients in the emergency open surgery group ( P = .03). Conclusions Self-expanding metal stents serve as a safe and effective bridge to subsequent laparoscopic surgery in patients with obstructing left-sided colon cancer. This endolaparoscopic approach makes a 1-Stage Operation more feasible, is associated with reduced incidence of stoma creation, and allows patients with malignant large-bowel obstruction to enjoy the full benefit of minimally invasive surgery. Trial Registration clinicaltrials.gov Identifier:NCT00654212
Yoshihiko Fujinaka - One of the best experts on this subject based on the ideXlab platform.
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two Stage Operation for high risk patients with thoracic esophageal cancer an old Operation revisited
Annals of Surgical Oncology, 2011Co-Authors: Masaru Morita, Hiroshi Saeki, Tomonori Nakanoko, Nobuhide Kubo, Yoshihiko Fujinaka, Keisuke Ikeda, Akinori Egashira, Hideaki Uchiyama, Takefumi Ohga, Yoshihiro KakejiAbstract:PURPOSE: An esophagectomy followed by reconstruction for esophageal cancer is a highly aggressive Operation. The purpose of this study was to justify a two-Stage Operation for high-risk patients with esophageal cancer. METHODS: The clinical results of 27 patients who underwent two-Stage Operation were compared with 118 patients who underwent a simultaneous resection and reconstruction (control subjects). The reasons for the selection of the two-Stage Operation were underlying general disease in 13 patients (liver dysfunction, n = 6; pulmonary disease, n = 3; poor performance status, n = 2; diabetes and renal failure, n = 1 each) and high-risk Operation in 14 other patients (colon interposition, n = 7; salvage Operation after definitive chemoradiotherapy, n = 4; and intraoperative events, n = 3). The patients initially underwent an esophagectomy and a cervical esophagostomy. Reconstruction was usually performed 2-3 weeks later. RESULTS: The patients in the two-Stage group were older than the control patients (mean 67.8 vs. 61.6 years old). The morbidity rate of the two-Stage Operation was 29.6%, which was not statistically different than control patients (32.2%). Postoperative complications in the two-Stage Operation were anastomotic leakage in 5 patients, and pneumonia and wound infection in 1 patient each. No patient experienced in-hospital death. The survival rates were not statistically different between the two groups. CONCLUSION: A two-Stage Operation is a safe Operation that prevents the occurrence of critical postoperative complications, and it thus may be considered an important treatment strategy for high-risk patients with esophageal cancer.
Tomonori Nakanoko - One of the best experts on this subject based on the ideXlab platform.
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two Stage Operation for high risk patients with thoracic esophageal cancer an old Operation revisited
Annals of Surgical Oncology, 2011Co-Authors: Masaru Morita, Hiroshi Saeki, Tomonori Nakanoko, Nobuhide Kubo, Yoshihiko Fujinaka, Keisuke Ikeda, Akinori Egashira, Hideaki Uchiyama, Takefumi Ohga, Yoshihiro KakejiAbstract:PURPOSE: An esophagectomy followed by reconstruction for esophageal cancer is a highly aggressive Operation. The purpose of this study was to justify a two-Stage Operation for high-risk patients with esophageal cancer. METHODS: The clinical results of 27 patients who underwent two-Stage Operation were compared with 118 patients who underwent a simultaneous resection and reconstruction (control subjects). The reasons for the selection of the two-Stage Operation were underlying general disease in 13 patients (liver dysfunction, n = 6; pulmonary disease, n = 3; poor performance status, n = 2; diabetes and renal failure, n = 1 each) and high-risk Operation in 14 other patients (colon interposition, n = 7; salvage Operation after definitive chemoradiotherapy, n = 4; and intraoperative events, n = 3). The patients initially underwent an esophagectomy and a cervical esophagostomy. Reconstruction was usually performed 2-3 weeks later. RESULTS: The patients in the two-Stage group were older than the control patients (mean 67.8 vs. 61.6 years old). The morbidity rate of the two-Stage Operation was 29.6%, which was not statistically different than control patients (32.2%). Postoperative complications in the two-Stage Operation were anastomotic leakage in 5 patients, and pneumonia and wound infection in 1 patient each. No patient experienced in-hospital death. The survival rates were not statistically different between the two groups. CONCLUSION: A two-Stage Operation is a safe Operation that prevents the occurrence of critical postoperative complications, and it thus may be considered an important treatment strategy for high-risk patients with esophageal cancer.
