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Nizar Souayah - One of the best experts on this subject based on the ideXlab platform.

  • myasthenia gravis therapeutic intervention charges comparison a new york State Planning and research cooperation system database analysis 1998 2014 p6 455
    Neurology, 2018
    Co-Authors: Janaki Patel, Shuja Sheikh, Abu Nasar, Nizar Souayah
    Abstract:

    Objective: To investigate the charges of Intravenous-Immunoglobulin (IVIG), Steroids, and Plasmapheresis in Myasthenia Gravis (MG) crisis treatment. Background: Plasmapheresis, IVIG, and Corticosteroids have been used for the treatment of MG Crisis. Design/Methods: We utilized data from the New York Statewide Planning and Research Cooperation System database for the 1998–2014 period. Data was analyzed using IBM PSPP software. Results: 969 patients over age of 18 years old with MG crisis were identified (mean age 61.6 years±18.5, 43.6% of whom were male) of which 49% were over age 65 years. 51.7% were treated with IVIG, 43% with plasmapheresis and 5% with steroids. More patients treated with plasmapheresis required mechanical ventilation compared to those treated with IVIG and steroids respectively (24% vs 10%, vs 12%). Plasmapheresis treated patients had longer average hospitalization stay as compared to IVIG treated and steroid treated patients (11 vs 5 vs 6 days respectively, p-values Conclusions: Our study demonstrated that hospitalization charges of MG crisis depend on disease severity and treatment modality with highest charges observed in the subgroup mechanically ventilated and treated with plasmapheresis. Work in progress to determine whether total average charge of MG crisis is related to the preferential treatment of patients with more severe disease with plasmapheresis and the influence of comorbid conditions on average total hospitalization charges. Study Supported by: Unrestricted Grant from RAM Capital Department Startup Fund Disclosure: Dr. Patel has nothing to disclose. Dr. Sheikh has nothing to disclose. Dr. Nasar has nothing to disclose. Dr. Souayah has nothing to disclose.

  • disposition of patients diagnosed with myasthenia gravis crisis a new york State Planning and research cooperation system database analysis 1998 2014 p6 447
    Neurology, 2018
    Co-Authors: Shuja Sheikh, Janaki Patel, Abu Nasar, Nizar Souayah
    Abstract:

    Objective: To investigate the relationship between the type of therapeutic intervention and disposition of patients diagnosed with MG crisis. Background: Plasmapheresis, Intravenous Immunoglobulin and Corticosteroids have been used for the treatment of Myasthenia Gravis (MG) Crisis. Design/Methods: We utilized data from the New York Statewide Planning and Research Cooperation System database for the 1998–2014 period. Data was analyzed using IBM PSPP software. Results: A total of 969 patients with MG crisis were identified (mean age 61.6 years ± 18.5, 43.6% of whom were male) of which 51.7% were treated with IVIG, 43% with plasmapheresis and 5% with steroids. Significantly more patients treated with plasmapheresis were discharged to skilled nursing facility/short term hospital when compared to IVIG (43% vs. 28%, p-value Conclusions: Discharge to home was significantly higher in patients diagnosed with MG crisis treated with IVIG relative to those treated with plasmapheresis and steroids. Work in progress to investigate whether disposition of patients with MG crisis is related to the fact that patients with less severe disease were preferentially treated with IVIG, influence of comorbid conditions on therapeutic intervention efficacy, and the impact of socioeconomic factors on disposition and therapy efficacy. Study Supported by: Unrestricted Grant from RAM Capital Department Start Up Fund Disclosure: Dr. Sheikh has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Nasar has nothing to disclose. Dr. Souayah has nothing to disclose.

  • association between amyotrophic lateral sclerosis and diabetes mellitus type i and ii a new york State Planning and research cooperation system database analysis 1998 2014 p6 461
    Neurology, 2018
    Co-Authors: Abu Nasar, Shuja Sheikh, Nizar Souayah
    Abstract:

    Objective: To investigate the association between Diabetes mellitus(DM)Type I and II and Amyotrophic Lateral Sclerosis(ALS) Background: Previous studies suggested that diabetes may delay ALS onset and slow its progression. We previously observed that patients with ALS and diabetes have older age compared to ALS-patients without diabetes Design/Methods: We used data from New-York-Statewide-Planning-and-Research-Cooperation - System-database for the 1998–2014-period. Results: A total of 7102 patients with ALS were reported (mean age 64.5 years ±13.5, 55% of whom were male) of which 0.59% had DMI and 9.6% had DMII. Mean age of ALS patients with DM was significantly higher than ALS patients age without DM (66.2 years ±11.9; 64.5 years ±13.6;p Conclusions: Our study demonstrated no significant difference in the age, death rate and hospice discharge of ALS patients diagnosed with diabetes compared to ALS patients without diabetes. Patients diagnosed with ALS were more likely to be discharged to skilled nursing facility or short-term hospital if they have DMII as a comorbidity, but not DMI. Patients with DMII were also less likely to be discharged to home as compared to ALS patients without DMII. Work in progress to investigate the effect of diabetes on the rate of respiratory failure, intubation, tracheostomy and hospitalization in ALS patients. Study Supported by: Unrestricted grant from RAM capital Department start up fund Disclosure: Dr. Nasar has nothing to disclose. Dr. Sheikh has nothing to disclose. Dr. Souayah has nothing to disclose.

Abu Nasar - One of the best experts on this subject based on the ideXlab platform.

  • myasthenia gravis therapeutic intervention charges comparison a new york State Planning and research cooperation system database analysis 1998 2014 p6 455
    Neurology, 2018
    Co-Authors: Janaki Patel, Shuja Sheikh, Abu Nasar, Nizar Souayah
    Abstract:

    Objective: To investigate the charges of Intravenous-Immunoglobulin (IVIG), Steroids, and Plasmapheresis in Myasthenia Gravis (MG) crisis treatment. Background: Plasmapheresis, IVIG, and Corticosteroids have been used for the treatment of MG Crisis. Design/Methods: We utilized data from the New York Statewide Planning and Research Cooperation System database for the 1998–2014 period. Data was analyzed using IBM PSPP software. Results: 969 patients over age of 18 years old with MG crisis were identified (mean age 61.6 years±18.5, 43.6% of whom were male) of which 49% were over age 65 years. 51.7% were treated with IVIG, 43% with plasmapheresis and 5% with steroids. More patients treated with plasmapheresis required mechanical ventilation compared to those treated with IVIG and steroids respectively (24% vs 10%, vs 12%). Plasmapheresis treated patients had longer average hospitalization stay as compared to IVIG treated and steroid treated patients (11 vs 5 vs 6 days respectively, p-values Conclusions: Our study demonstrated that hospitalization charges of MG crisis depend on disease severity and treatment modality with highest charges observed in the subgroup mechanically ventilated and treated with plasmapheresis. Work in progress to determine whether total average charge of MG crisis is related to the preferential treatment of patients with more severe disease with plasmapheresis and the influence of comorbid conditions on average total hospitalization charges. Study Supported by: Unrestricted Grant from RAM Capital Department Startup Fund Disclosure: Dr. Patel has nothing to disclose. Dr. Sheikh has nothing to disclose. Dr. Nasar has nothing to disclose. Dr. Souayah has nothing to disclose.

  • disposition of patients diagnosed with myasthenia gravis crisis a new york State Planning and research cooperation system database analysis 1998 2014 p6 447
    Neurology, 2018
    Co-Authors: Shuja Sheikh, Janaki Patel, Abu Nasar, Nizar Souayah
    Abstract:

    Objective: To investigate the relationship between the type of therapeutic intervention and disposition of patients diagnosed with MG crisis. Background: Plasmapheresis, Intravenous Immunoglobulin and Corticosteroids have been used for the treatment of Myasthenia Gravis (MG) Crisis. Design/Methods: We utilized data from the New York Statewide Planning and Research Cooperation System database for the 1998–2014 period. Data was analyzed using IBM PSPP software. Results: A total of 969 patients with MG crisis were identified (mean age 61.6 years ± 18.5, 43.6% of whom were male) of which 51.7% were treated with IVIG, 43% with plasmapheresis and 5% with steroids. Significantly more patients treated with plasmapheresis were discharged to skilled nursing facility/short term hospital when compared to IVIG (43% vs. 28%, p-value Conclusions: Discharge to home was significantly higher in patients diagnosed with MG crisis treated with IVIG relative to those treated with plasmapheresis and steroids. Work in progress to investigate whether disposition of patients with MG crisis is related to the fact that patients with less severe disease were preferentially treated with IVIG, influence of comorbid conditions on therapeutic intervention efficacy, and the impact of socioeconomic factors on disposition and therapy efficacy. Study Supported by: Unrestricted Grant from RAM Capital Department Start Up Fund Disclosure: Dr. Sheikh has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Nasar has nothing to disclose. Dr. Souayah has nothing to disclose.

  • association between amyotrophic lateral sclerosis and diabetes mellitus type i and ii a new york State Planning and research cooperation system database analysis 1998 2014 p6 461
    Neurology, 2018
    Co-Authors: Abu Nasar, Shuja Sheikh, Nizar Souayah
    Abstract:

    Objective: To investigate the association between Diabetes mellitus(DM)Type I and II and Amyotrophic Lateral Sclerosis(ALS) Background: Previous studies suggested that diabetes may delay ALS onset and slow its progression. We previously observed that patients with ALS and diabetes have older age compared to ALS-patients without diabetes Design/Methods: We used data from New-York-Statewide-Planning-and-Research-Cooperation - System-database for the 1998–2014-period. Results: A total of 7102 patients with ALS were reported (mean age 64.5 years ±13.5, 55% of whom were male) of which 0.59% had DMI and 9.6% had DMII. Mean age of ALS patients with DM was significantly higher than ALS patients age without DM (66.2 years ±11.9; 64.5 years ±13.6;p Conclusions: Our study demonstrated no significant difference in the age, death rate and hospice discharge of ALS patients diagnosed with diabetes compared to ALS patients without diabetes. Patients diagnosed with ALS were more likely to be discharged to skilled nursing facility or short-term hospital if they have DMII as a comorbidity, but not DMI. Patients with DMII were also less likely to be discharged to home as compared to ALS patients without DMII. Work in progress to investigate the effect of diabetes on the rate of respiratory failure, intubation, tracheostomy and hospitalization in ALS patients. Study Supported by: Unrestricted grant from RAM capital Department start up fund Disclosure: Dr. Nasar has nothing to disclose. Dr. Sheikh has nothing to disclose. Dr. Souayah has nothing to disclose.

Shuja Sheikh - One of the best experts on this subject based on the ideXlab platform.

  • myasthenia gravis therapeutic intervention charges comparison a new york State Planning and research cooperation system database analysis 1998 2014 p6 455
    Neurology, 2018
    Co-Authors: Janaki Patel, Shuja Sheikh, Abu Nasar, Nizar Souayah
    Abstract:

    Objective: To investigate the charges of Intravenous-Immunoglobulin (IVIG), Steroids, and Plasmapheresis in Myasthenia Gravis (MG) crisis treatment. Background: Plasmapheresis, IVIG, and Corticosteroids have been used for the treatment of MG Crisis. Design/Methods: We utilized data from the New York Statewide Planning and Research Cooperation System database for the 1998–2014 period. Data was analyzed using IBM PSPP software. Results: 969 patients over age of 18 years old with MG crisis were identified (mean age 61.6 years±18.5, 43.6% of whom were male) of which 49% were over age 65 years. 51.7% were treated with IVIG, 43% with plasmapheresis and 5% with steroids. More patients treated with plasmapheresis required mechanical ventilation compared to those treated with IVIG and steroids respectively (24% vs 10%, vs 12%). Plasmapheresis treated patients had longer average hospitalization stay as compared to IVIG treated and steroid treated patients (11 vs 5 vs 6 days respectively, p-values Conclusions: Our study demonstrated that hospitalization charges of MG crisis depend on disease severity and treatment modality with highest charges observed in the subgroup mechanically ventilated and treated with plasmapheresis. Work in progress to determine whether total average charge of MG crisis is related to the preferential treatment of patients with more severe disease with plasmapheresis and the influence of comorbid conditions on average total hospitalization charges. Study Supported by: Unrestricted Grant from RAM Capital Department Startup Fund Disclosure: Dr. Patel has nothing to disclose. Dr. Sheikh has nothing to disclose. Dr. Nasar has nothing to disclose. Dr. Souayah has nothing to disclose.

  • disposition of patients diagnosed with myasthenia gravis crisis a new york State Planning and research cooperation system database analysis 1998 2014 p6 447
    Neurology, 2018
    Co-Authors: Shuja Sheikh, Janaki Patel, Abu Nasar, Nizar Souayah
    Abstract:

    Objective: To investigate the relationship between the type of therapeutic intervention and disposition of patients diagnosed with MG crisis. Background: Plasmapheresis, Intravenous Immunoglobulin and Corticosteroids have been used for the treatment of Myasthenia Gravis (MG) Crisis. Design/Methods: We utilized data from the New York Statewide Planning and Research Cooperation System database for the 1998–2014 period. Data was analyzed using IBM PSPP software. Results: A total of 969 patients with MG crisis were identified (mean age 61.6 years ± 18.5, 43.6% of whom were male) of which 51.7% were treated with IVIG, 43% with plasmapheresis and 5% with steroids. Significantly more patients treated with plasmapheresis were discharged to skilled nursing facility/short term hospital when compared to IVIG (43% vs. 28%, p-value Conclusions: Discharge to home was significantly higher in patients diagnosed with MG crisis treated with IVIG relative to those treated with plasmapheresis and steroids. Work in progress to investigate whether disposition of patients with MG crisis is related to the fact that patients with less severe disease were preferentially treated with IVIG, influence of comorbid conditions on therapeutic intervention efficacy, and the impact of socioeconomic factors on disposition and therapy efficacy. Study Supported by: Unrestricted Grant from RAM Capital Department Start Up Fund Disclosure: Dr. Sheikh has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Nasar has nothing to disclose. Dr. Souayah has nothing to disclose.

  • association between amyotrophic lateral sclerosis and diabetes mellitus type i and ii a new york State Planning and research cooperation system database analysis 1998 2014 p6 461
    Neurology, 2018
    Co-Authors: Abu Nasar, Shuja Sheikh, Nizar Souayah
    Abstract:

    Objective: To investigate the association between Diabetes mellitus(DM)Type I and II and Amyotrophic Lateral Sclerosis(ALS) Background: Previous studies suggested that diabetes may delay ALS onset and slow its progression. We previously observed that patients with ALS and diabetes have older age compared to ALS-patients without diabetes Design/Methods: We used data from New-York-Statewide-Planning-and-Research-Cooperation - System-database for the 1998–2014-period. Results: A total of 7102 patients with ALS were reported (mean age 64.5 years ±13.5, 55% of whom were male) of which 0.59% had DMI and 9.6% had DMII. Mean age of ALS patients with DM was significantly higher than ALS patients age without DM (66.2 years ±11.9; 64.5 years ±13.6;p Conclusions: Our study demonstrated no significant difference in the age, death rate and hospice discharge of ALS patients diagnosed with diabetes compared to ALS patients without diabetes. Patients diagnosed with ALS were more likely to be discharged to skilled nursing facility or short-term hospital if they have DMII as a comorbidity, but not DMI. Patients with DMII were also less likely to be discharged to home as compared to ALS patients without DMII. Work in progress to investigate the effect of diabetes on the rate of respiratory failure, intubation, tracheostomy and hospitalization in ALS patients. Study Supported by: Unrestricted grant from RAM capital Department start up fund Disclosure: Dr. Nasar has nothing to disclose. Dr. Sheikh has nothing to disclose. Dr. Souayah has nothing to disclose.

Janaki Patel - One of the best experts on this subject based on the ideXlab platform.

  • myasthenia gravis therapeutic intervention charges comparison a new york State Planning and research cooperation system database analysis 1998 2014 p6 455
    Neurology, 2018
    Co-Authors: Janaki Patel, Shuja Sheikh, Abu Nasar, Nizar Souayah
    Abstract:

    Objective: To investigate the charges of Intravenous-Immunoglobulin (IVIG), Steroids, and Plasmapheresis in Myasthenia Gravis (MG) crisis treatment. Background: Plasmapheresis, IVIG, and Corticosteroids have been used for the treatment of MG Crisis. Design/Methods: We utilized data from the New York Statewide Planning and Research Cooperation System database for the 1998–2014 period. Data was analyzed using IBM PSPP software. Results: 969 patients over age of 18 years old with MG crisis were identified (mean age 61.6 years±18.5, 43.6% of whom were male) of which 49% were over age 65 years. 51.7% were treated with IVIG, 43% with plasmapheresis and 5% with steroids. More patients treated with plasmapheresis required mechanical ventilation compared to those treated with IVIG and steroids respectively (24% vs 10%, vs 12%). Plasmapheresis treated patients had longer average hospitalization stay as compared to IVIG treated and steroid treated patients (11 vs 5 vs 6 days respectively, p-values Conclusions: Our study demonstrated that hospitalization charges of MG crisis depend on disease severity and treatment modality with highest charges observed in the subgroup mechanically ventilated and treated with plasmapheresis. Work in progress to determine whether total average charge of MG crisis is related to the preferential treatment of patients with more severe disease with plasmapheresis and the influence of comorbid conditions on average total hospitalization charges. Study Supported by: Unrestricted Grant from RAM Capital Department Startup Fund Disclosure: Dr. Patel has nothing to disclose. Dr. Sheikh has nothing to disclose. Dr. Nasar has nothing to disclose. Dr. Souayah has nothing to disclose.

  • disposition of patients diagnosed with myasthenia gravis crisis a new york State Planning and research cooperation system database analysis 1998 2014 p6 447
    Neurology, 2018
    Co-Authors: Shuja Sheikh, Janaki Patel, Abu Nasar, Nizar Souayah
    Abstract:

    Objective: To investigate the relationship between the type of therapeutic intervention and disposition of patients diagnosed with MG crisis. Background: Plasmapheresis, Intravenous Immunoglobulin and Corticosteroids have been used for the treatment of Myasthenia Gravis (MG) Crisis. Design/Methods: We utilized data from the New York Statewide Planning and Research Cooperation System database for the 1998–2014 period. Data was analyzed using IBM PSPP software. Results: A total of 969 patients with MG crisis were identified (mean age 61.6 years ± 18.5, 43.6% of whom were male) of which 51.7% were treated with IVIG, 43% with plasmapheresis and 5% with steroids. Significantly more patients treated with plasmapheresis were discharged to skilled nursing facility/short term hospital when compared to IVIG (43% vs. 28%, p-value Conclusions: Discharge to home was significantly higher in patients diagnosed with MG crisis treated with IVIG relative to those treated with plasmapheresis and steroids. Work in progress to investigate whether disposition of patients with MG crisis is related to the fact that patients with less severe disease were preferentially treated with IVIG, influence of comorbid conditions on therapeutic intervention efficacy, and the impact of socioeconomic factors on disposition and therapy efficacy. Study Supported by: Unrestricted Grant from RAM Capital Department Start Up Fund Disclosure: Dr. Sheikh has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Nasar has nothing to disclose. Dr. Souayah has nothing to disclose.

Frank T Lorne - One of the best experts on this subject based on the ideXlab platform.