The Experts below are selected from a list of 609 Experts worldwide ranked by ideXlab platform

Gary S Mintz - One of the best experts on this subject based on the ideXlab platform.

  • In-Stent restenosis characteristics and repeat Stenting Underexpansion: insights from optical coherence tomography.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2020
    Co-Authors: Dong Yin, Jeffrey W. Moses, Gary S Mintz, Tetsumin Lee, Lei Song, Zhaoyang Chen, Ajay J. Kirtane, Manish Parikh, Khady Fall, Allen Jeremias
    Abstract:

    Aims The aim of this study was to use optical coherence tomography (OCT) to predict newly implanted Stent expansion for treatment of in-Stent restenosis (ISR). Methods and results With OCT guidance, 143 ISR lesions were treated with a new Stent. Stent Underexpansion was defined as minimum Stent area (MSA) 180°, and maximum calcium thickness >0.5 mm were independently associated with new Stent Underexpansion. Patients with new Stent Underexpansion had a higher prevalence of major adverse cardiac events (35.5% vs 14.3%, p=0.009), mainly driven by a higher rate of myocardial infarction and target vessel revascularisation at two years. Conclusions When re-Stenting an ISR lesion, old Stent Underexpansion, the amount of neointimal or peri-Stent calcium, and multiple old Stent strut layers are important determinants of new Stent Underexpansion which is then associated with adverse long-term outcomes.

  • Intravascular Ultrasound Assessment of In-Stent Restenosis in Saphenous Vein Grafts.
    The American journal of cardiology, 2019
    Co-Authors: Rafal Wolny, Gary S Mintz, Mitsuaki Matsumura, Manish Parikh, Khady Fall, Ziad A. Ali, Masaru Ishida, Leroy E. Rabbani, Yuqi Fan, Dimitri Karmpaliotis
    Abstract:

    Outcomes after percutaneous coronary interventions (PCI) in saphenous vein grafts (SVG) are inferior compared with native coronary arteries, but the mechanisms of SVG in-Stent restenosis (ISR) have not been well-described. Thus, we aimed to evaluate the patterns of SVG ISR using intravascular ultrasound (IVUS) in 54 SVG ISR lesions. Stent Underexpansion was defined as minimum Stent area (MSA) 1 year after Stent implantation. In conclusion, SVG ISR is dominated by biological patterns including neoatherosclerosis. Mechanical patterns of SVG ISR are associated with earlier presentation and location at graft anastomosis or hinge motion site.

  • TCT-355 Serial (Baseline and Follow-Up) Optical Coherence Tomography Analysis of the Causes of Stent Failure
    Journal of the American College of Cardiology, 2019
    Co-Authors: Mingyou Zhang, Gary S Mintz, Mitsuaki Matsumura, Zhaoyang Chen, Thomas Pappas, Ziad A. Ali, Masaru Ishida, Craig Porter, Jane Cao, Jeffrey W. Moses
    Abstract:

    In-Stent restenosis (ISR) can be caused by neointimal hyperplasia, chronic Stent Underexpansion, or mechanical problems that develop during follow-up. A total of 45 patients had optical coherence tomography (OCT) at the time of second-generation drug-eluting Stent implantation and for treatment of

  • Intravascular imaging and coronary calcification
    Coronary Calcium, 2019
    Co-Authors: Akiko Maehara, Ziad A. Ali, Mitsuaki Matsumura, Gary S Mintz
    Abstract:

    Abstract Intravascular ultrasound (IVUS) and optical coherence tomography are more sensitive in detecting coronary calcification compared with coronary angiography. The key to predicting successful Stent expansion in a calcified lesion is the total amount of calcium (calcium thickness, angle, and length). The main mechanism of atherectomy is to remove a small amount of superficial calcium (calcium modification) to facilitate calcium fracture, and the mechanism of other devices (cutting or scoring balloon, excimer laser, or lithotripsy) is not removal of calcium, but calcium fracture. Causes of in-Stent restenosis in the drug-eluting Stent era include Stent Underexpansion, often from peri-Stent calcium, and neoatherosclerotic calcification. Although understanding the mechanism of each case of in-Stent restenosis is important, avoiding Stent Underexpansion from underlying calcium at the time of first Stent implantation is far more important.

  • A new optical coherence tomography-based calcium scoring system to predict Stent Underexpansion.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Tetsumin Lee, Song-yi Kim, Masahiro Hoshino, Eisuke Usui, Taishi Yonetsu, Elizabeth S Haag, Richard A Shlofmitz
    Abstract:

    This was a retrospective study to develop and validate an optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. A calcium score was developed using 128 patients with pre- and post-Stent OCT (test cohort) and then validated in an external cohort of 133 patients. In the test cohort, a multivariable model showed that the independent predictors of Stent expansion were maximum calcium angle per 180° (regression coefficient: -7.43; p<0.01), maximum calcium thickness per 0.5 mm (-3.40; p=0.02), and calcium length per 5 mm (-2.32; p=0.01). A calcium score was then defined as 2 points for maximum angle >180°, 1 point for maximum thickness >0.5 mm, and 1 point for length >5 mm. In the validation cohort, the lesions with calcium score of 0 to 3 had excellent Stent expansion, whereas the lesions with a score of 4 had poor Stent expansion (96% versus 78%, p<0.01). On multivariate analysis the calcium score was an independent predictor of Stent Underexpansion. An OCT-based calcium scoring system can help to identify lesions that would benefit from plaque modification prior to Stent implantation. Lesions with calcium deposit with maximum angle >180°, maximum thickness >0.5 mm, and length >5 mm may be at risk of Stent Underexpansion.

Mitsuaki Matsumura - One of the best experts on this subject based on the ideXlab platform.

  • Intravascular Ultrasound Assessment of In-Stent Restenosis in Saphenous Vein Grafts.
    The American journal of cardiology, 2019
    Co-Authors: Rafal Wolny, Gary S Mintz, Mitsuaki Matsumura, Manish Parikh, Khady Fall, Ziad A. Ali, Masaru Ishida, Leroy E. Rabbani, Yuqi Fan, Dimitri Karmpaliotis
    Abstract:

    Outcomes after percutaneous coronary interventions (PCI) in saphenous vein grafts (SVG) are inferior compared with native coronary arteries, but the mechanisms of SVG in-Stent restenosis (ISR) have not been well-described. Thus, we aimed to evaluate the patterns of SVG ISR using intravascular ultrasound (IVUS) in 54 SVG ISR lesions. Stent Underexpansion was defined as minimum Stent area (MSA) 1 year after Stent implantation. In conclusion, SVG ISR is dominated by biological patterns including neoatherosclerosis. Mechanical patterns of SVG ISR are associated with earlier presentation and location at graft anastomosis or hinge motion site.

  • Intravascular imaging and coronary calcification
    Coronary Calcium, 2019
    Co-Authors: Akiko Maehara, Ziad A. Ali, Mitsuaki Matsumura, Gary S Mintz
    Abstract:

    Abstract Intravascular ultrasound (IVUS) and optical coherence tomography are more sensitive in detecting coronary calcification compared with coronary angiography. The key to predicting successful Stent expansion in a calcified lesion is the total amount of calcium (calcium thickness, angle, and length). The main mechanism of atherectomy is to remove a small amount of superficial calcium (calcium modification) to facilitate calcium fracture, and the mechanism of other devices (cutting or scoring balloon, excimer laser, or lithotripsy) is not removal of calcium, but calcium fracture. Causes of in-Stent restenosis in the drug-eluting Stent era include Stent Underexpansion, often from peri-Stent calcium, and neoatherosclerotic calcification. Although understanding the mechanism of each case of in-Stent restenosis is important, avoiding Stent Underexpansion from underlying calcium at the time of first Stent implantation is far more important.

  • TCT-355 Serial (Baseline and Follow-Up) Optical Coherence Tomography Analysis of the Causes of Stent Failure
    Journal of the American College of Cardiology, 2019
    Co-Authors: Mingyou Zhang, Gary S Mintz, Mitsuaki Matsumura, Zhaoyang Chen, Thomas Pappas, Ziad A. Ali, Masaru Ishida, Craig Porter, Jane Cao, Jeffrey W. Moses
    Abstract:

    In-Stent restenosis (ISR) can be caused by neointimal hyperplasia, chronic Stent Underexpansion, or mechanical problems that develop during follow-up. A total of 45 patients had optical coherence tomography (OCT) at the time of second-generation drug-eluting Stent implantation and for treatment of

  • TCT-51 IVUS Predictors of Stent Expansion in Severely Calcified Lesions
    Journal of the American College of Cardiology, 2019
    Co-Authors: Mingyou Zhang, Mitsuaki Matsumura, Eisuke Usui, Khady Fall, Masahiko Noguchi, Tatsuhiro Fujimura, Tamim Nazif, Sahil A. Parikh, Leroy E. Rabbani, Manish Parikh
    Abstract:

    Severe calcium (Ca) often but not always limits Stent expansion. We sought to develop an intravascular ultrasound (IVUS) Ca score that predicts Stent Underexpansion (ST-UEx) in lesions with severe Ca. A total of 77 lesions in 77 patients with max pre-percutaneous coronary intervention (PCI) Ca arc

  • A new optical coherence tomography-based calcium scoring system to predict Stent Underexpansion.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Tetsumin Lee, Song-yi Kim, Masahiro Hoshino, Eisuke Usui, Taishi Yonetsu, Elizabeth S Haag, Richard A Shlofmitz
    Abstract:

    This was a retrospective study to develop and validate an optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. A calcium score was developed using 128 patients with pre- and post-Stent OCT (test cohort) and then validated in an external cohort of 133 patients. In the test cohort, a multivariable model showed that the independent predictors of Stent expansion were maximum calcium angle per 180° (regression coefficient: -7.43; p<0.01), maximum calcium thickness per 0.5 mm (-3.40; p=0.02), and calcium length per 5 mm (-2.32; p=0.01). A calcium score was then defined as 2 points for maximum angle >180°, 1 point for maximum thickness >0.5 mm, and 1 point for length >5 mm. In the validation cohort, the lesions with calcium score of 0 to 3 had excellent Stent expansion, whereas the lesions with a score of 4 had poor Stent expansion (96% versus 78%, p<0.01). On multivariate analysis the calcium score was an independent predictor of Stent Underexpansion. An OCT-based calcium scoring system can help to identify lesions that would benefit from plaque modification prior to Stent implantation. Lesions with calcium deposit with maximum angle >180°, maximum thickness >0.5 mm, and length >5 mm may be at risk of Stent Underexpansion.

Eisuke Usui - One of the best experts on this subject based on the ideXlab platform.

  • TCT-51 IVUS Predictors of Stent Expansion in Severely Calcified Lesions
    Journal of the American College of Cardiology, 2019
    Co-Authors: Mingyou Zhang, Mitsuaki Matsumura, Eisuke Usui, Khady Fall, Masahiko Noguchi, Tatsuhiro Fujimura, Tamim Nazif, Sahil A. Parikh, Leroy E. Rabbani, Manish Parikh
    Abstract:

    Severe calcium (Ca) often but not always limits Stent expansion. We sought to develop an intravascular ultrasound (IVUS) Ca score that predicts Stent Underexpansion (ST-UEx) in lesions with severe Ca. A total of 77 lesions in 77 patients with max pre-percutaneous coronary intervention (PCI) Ca arc

  • A new optical coherence tomography-based calcium scoring system to predict Stent Underexpansion.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Tetsumin Lee, Song-yi Kim, Masahiro Hoshino, Eisuke Usui, Taishi Yonetsu, Elizabeth S Haag, Richard A Shlofmitz
    Abstract:

    This was a retrospective study to develop and validate an optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. A calcium score was developed using 128 patients with pre- and post-Stent OCT (test cohort) and then validated in an external cohort of 133 patients. In the test cohort, a multivariable model showed that the independent predictors of Stent expansion were maximum calcium angle per 180° (regression coefficient: -7.43; p<0.01), maximum calcium thickness per 0.5 mm (-3.40; p=0.02), and calcium length per 5 mm (-2.32; p=0.01). A calcium score was then defined as 2 points for maximum angle >180°, 1 point for maximum thickness >0.5 mm, and 1 point for length >5 mm. In the validation cohort, the lesions with calcium score of 0 to 3 had excellent Stent expansion, whereas the lesions with a score of 4 had poor Stent expansion (96% versus 78%, p<0.01). On multivariate analysis the calcium score was an independent predictor of Stent Underexpansion. An OCT-based calcium scoring system can help to identify lesions that would benefit from plaque modification prior to Stent implantation. Lesions with calcium deposit with maximum angle >180°, maximum thickness >0.5 mm, and length >5 mm may be at risk of Stent Underexpansion.

  • A new optical coherence tomography-based calcium scoring system to predict Stent Underexpansion.
    EuroIntervention, 2018
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Tetsumin Lee, Song-yi Kim, Masahiro Hoshino, Eisuke Usui, Taishi Yonetsu, Elizabeth Haag, Richard A Shlofmitz
    Abstract:

    Aims This was a retrospective study to develop and validate an optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. Methods and results A calcium score was developed using 128 patients with pre- and post-Stent OCT (test cohort) and then validated in an external cohort of 133 patients. In the test cohort, a multivariable model showed that the independent predictors of Stent expansion were maximum calcium angle per 180° (regression coefficient: -7.43; p 180°, 1 point for maximum thickness >0.5 mm, and 1 point for length >5 mm. In the validation cohort, the lesions with calcium score of 0 to 3 had excellent Stent expansion, whereas the lesions with a score of 4 had poor Stent expansion (96% versus 78%, p Conclusions An OCT-based calcium scoring system can help to identify lesions that would benefit from plaque modification prior to Stent implantation. Lesions with calcium deposit with maximum angle >180°, maximum thickness >0.5 mm, and length >5 mm may be at risk of Stent Underexpansion.

  • TCT-28 A New Optical Coherence Tomography-Based Calcium Scoring System to Predict Stent Underexpansion
    Journal of the American College of Cardiology, 2017
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Masahiro Hoshino, Eisuke Usui, Myong Hwa Yamamoto, Cheolmin Lee, Yoshihisa Kanaji, Tadashi Murai, Taishi Yonetsu
    Abstract:

    We sought to develop and validate a new optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. After excluding lesions treated with atherectomy or without any calcium, a calcium volume index (CVI) was developed using 128 pts with pre- and post-Stent OCT (

Taishi Yonetsu - One of the best experts on this subject based on the ideXlab platform.

  • A new optical coherence tomography-based calcium scoring system to predict Stent Underexpansion.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Tetsumin Lee, Song-yi Kim, Masahiro Hoshino, Eisuke Usui, Taishi Yonetsu, Elizabeth S Haag, Richard A Shlofmitz
    Abstract:

    This was a retrospective study to develop and validate an optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. A calcium score was developed using 128 patients with pre- and post-Stent OCT (test cohort) and then validated in an external cohort of 133 patients. In the test cohort, a multivariable model showed that the independent predictors of Stent expansion were maximum calcium angle per 180° (regression coefficient: -7.43; p<0.01), maximum calcium thickness per 0.5 mm (-3.40; p=0.02), and calcium length per 5 mm (-2.32; p=0.01). A calcium score was then defined as 2 points for maximum angle >180°, 1 point for maximum thickness >0.5 mm, and 1 point for length >5 mm. In the validation cohort, the lesions with calcium score of 0 to 3 had excellent Stent expansion, whereas the lesions with a score of 4 had poor Stent expansion (96% versus 78%, p<0.01). On multivariate analysis the calcium score was an independent predictor of Stent Underexpansion. An OCT-based calcium scoring system can help to identify lesions that would benefit from plaque modification prior to Stent implantation. Lesions with calcium deposit with maximum angle >180°, maximum thickness >0.5 mm, and length >5 mm may be at risk of Stent Underexpansion.

  • A new optical coherence tomography-based calcium scoring system to predict Stent Underexpansion.
    EuroIntervention, 2018
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Tetsumin Lee, Song-yi Kim, Masahiro Hoshino, Eisuke Usui, Taishi Yonetsu, Elizabeth Haag, Richard A Shlofmitz
    Abstract:

    Aims This was a retrospective study to develop and validate an optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. Methods and results A calcium score was developed using 128 patients with pre- and post-Stent OCT (test cohort) and then validated in an external cohort of 133 patients. In the test cohort, a multivariable model showed that the independent predictors of Stent expansion were maximum calcium angle per 180° (regression coefficient: -7.43; p 180°, 1 point for maximum thickness >0.5 mm, and 1 point for length >5 mm. In the validation cohort, the lesions with calcium score of 0 to 3 had excellent Stent expansion, whereas the lesions with a score of 4 had poor Stent expansion (96% versus 78%, p Conclusions An OCT-based calcium scoring system can help to identify lesions that would benefit from plaque modification prior to Stent implantation. Lesions with calcium deposit with maximum angle >180°, maximum thickness >0.5 mm, and length >5 mm may be at risk of Stent Underexpansion.

  • TCT-28 A New Optical Coherence Tomography-Based Calcium Scoring System to Predict Stent Underexpansion
    Journal of the American College of Cardiology, 2017
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Masahiro Hoshino, Eisuke Usui, Myong Hwa Yamamoto, Cheolmin Lee, Yoshihisa Kanaji, Tadashi Murai, Taishi Yonetsu
    Abstract:

    We sought to develop and validate a new optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. After excluding lesions treated with atherectomy or without any calcium, a calcium volume index (CVI) was developed using 128 pts with pre- and post-Stent OCT (

Akiko Fujino - One of the best experts on this subject based on the ideXlab platform.

  • A new optical coherence tomography-based calcium scoring system to predict Stent Underexpansion.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Tetsumin Lee, Song-yi Kim, Masahiro Hoshino, Eisuke Usui, Taishi Yonetsu, Elizabeth S Haag, Richard A Shlofmitz
    Abstract:

    This was a retrospective study to develop and validate an optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. A calcium score was developed using 128 patients with pre- and post-Stent OCT (test cohort) and then validated in an external cohort of 133 patients. In the test cohort, a multivariable model showed that the independent predictors of Stent expansion were maximum calcium angle per 180° (regression coefficient: -7.43; p<0.01), maximum calcium thickness per 0.5 mm (-3.40; p=0.02), and calcium length per 5 mm (-2.32; p=0.01). A calcium score was then defined as 2 points for maximum angle >180°, 1 point for maximum thickness >0.5 mm, and 1 point for length >5 mm. In the validation cohort, the lesions with calcium score of 0 to 3 had excellent Stent expansion, whereas the lesions with a score of 4 had poor Stent expansion (96% versus 78%, p<0.01). On multivariate analysis the calcium score was an independent predictor of Stent Underexpansion. An OCT-based calcium scoring system can help to identify lesions that would benefit from plaque modification prior to Stent implantation. Lesions with calcium deposit with maximum angle >180°, maximum thickness >0.5 mm, and length >5 mm may be at risk of Stent Underexpansion.

  • A new optical coherence tomography-based calcium scoring system to predict Stent Underexpansion.
    EuroIntervention, 2018
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Tetsumin Lee, Song-yi Kim, Masahiro Hoshino, Eisuke Usui, Taishi Yonetsu, Elizabeth Haag, Richard A Shlofmitz
    Abstract:

    Aims This was a retrospective study to develop and validate an optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. Methods and results A calcium score was developed using 128 patients with pre- and post-Stent OCT (test cohort) and then validated in an external cohort of 133 patients. In the test cohort, a multivariable model showed that the independent predictors of Stent expansion were maximum calcium angle per 180° (regression coefficient: -7.43; p 180°, 1 point for maximum thickness >0.5 mm, and 1 point for length >5 mm. In the validation cohort, the lesions with calcium score of 0 to 3 had excellent Stent expansion, whereas the lesions with a score of 4 had poor Stent expansion (96% versus 78%, p Conclusions An OCT-based calcium scoring system can help to identify lesions that would benefit from plaque modification prior to Stent implantation. Lesions with calcium deposit with maximum angle >180°, maximum thickness >0.5 mm, and length >5 mm may be at risk of Stent Underexpansion.

  • TCT-28 A New Optical Coherence Tomography-Based Calcium Scoring System to Predict Stent Underexpansion
    Journal of the American College of Cardiology, 2017
    Co-Authors: Akiko Fujino, Gary S Mintz, Mitsuaki Matsumura, Masahiro Hoshino, Eisuke Usui, Myong Hwa Yamamoto, Cheolmin Lee, Yoshihisa Kanaji, Tadashi Murai, Taishi Yonetsu
    Abstract:

    We sought to develop and validate a new optical coherence tomography (OCT)-based calcium scoring system to predict Stent Underexpansion. After excluding lesions treated with atherectomy or without any calcium, a calcium volume index (CVI) was developed using 128 pts with pre- and post-Stent OCT (