The Experts below are selected from a list of 231 Experts worldwide ranked by ideXlab platform
Gabriele Mazzacca - One of the best experts on this subject based on the ideXlab platform.
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Proximal Stomach Function in Systemic Sclerosis
Digestive Diseases and Sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
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Proximal Stomach Function in systemic sclerosis: relationship with autonomic nerve Function.
Digestive diseases and sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
Paola Iovino - One of the best experts on this subject based on the ideXlab platform.
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proximal Stomach Function in obesity with normal or abnormal oesophageal acid exposure
Neurogastroenterology and Motility, 2006Co-Authors: Paola Iovino, Luigi Angrisani, Giuseppe Galloro, D. Consalvo, F. Tremolaterra, A. Pascariello, Carolina CiacciAbstract:There is an increased prevalence of gastro- oesophageal reflux and symptoms in obese patients. Information about the proximal Stomach in obese patients with reflux is lacking. Gastric volume and compliance are similar between obese and lean sub- jects. To study the proximal Stomach Function and perception in obese patients with normal or abnormal oesophageal acid exposure, thirty-one obese patients, with normal or abnormal oesophageal acid exposure, underwent medical evaluation of oesophageal and gastrointestinal symptoms by a questionnaire and measurement of proximal Stomach Function and per- ception by an electronic barostat and a standardized questionnaire. Nineteen obese patients had abnormal oesophageal acid exposure. The percentage of total time with pH <4 is significantly related to the presence of hiatal hernia, the oesophageal intensity-frequency symptom score and gender, i.e. higher percentage in men. The perception cumulative score was sig- nificantly different between patients with normal and abnormal oesophageal acid exposure after adjusting for covariates (gender, body mass index, age, minimal distending pressure, gastric tone and gastric com- pliance). Gastric tone and compliance were sig- nificantly related to the perception cumulative score. In conclusion, patients with abnormal oesophageal acid exposure have increased gastric perception. A significant relation among gastric tone, gastric com- pliance and upper gastrointestinal sensations was shown.
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Proximal Stomach Function in obesity with normal or abnormal oesophageal acid exposure
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 2006Co-Authors: Paola Iovino, Luigi Angrisani, Giuseppe Galloro, D. Consalvo, F. Tremolaterra, A. Pascariello, Carolina CiacciAbstract:There is an increased prevalence of gastro- oesophageal reflux and symptoms in obese patients. Information about the proximal Stomach in obese patients with reflux is lacking. Gastric volume and compliance are similar between obese and lean sub- jects. To study the proximal Stomach Function and perception in obese patients with normal or abnormal oesophageal acid exposure, thirty-one obese patients, with normal or abnormal oesophageal acid exposure, underwent medical evaluation of oesophageal and gastrointestinal symptoms by a questionnaire and measurement of proximal Stomach Function and per- ception by an electronic barostat and a standardized questionnaire. Nineteen obese patients had abnormal oesophageal acid exposure. The percentage of total time with pH
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Proximal Stomach Function in Systemic Sclerosis
Digestive Diseases and Sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
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Proximal Stomach Function in systemic sclerosis: relationship with autonomic nerve Function.
Digestive diseases and sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
Carolina Ciacci - One of the best experts on this subject based on the ideXlab platform.
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proximal Stomach Function in obesity with normal or abnormal oesophageal acid exposure
Neurogastroenterology and Motility, 2006Co-Authors: Paola Iovino, Luigi Angrisani, Giuseppe Galloro, D. Consalvo, F. Tremolaterra, A. Pascariello, Carolina CiacciAbstract:There is an increased prevalence of gastro- oesophageal reflux and symptoms in obese patients. Information about the proximal Stomach in obese patients with reflux is lacking. Gastric volume and compliance are similar between obese and lean sub- jects. To study the proximal Stomach Function and perception in obese patients with normal or abnormal oesophageal acid exposure, thirty-one obese patients, with normal or abnormal oesophageal acid exposure, underwent medical evaluation of oesophageal and gastrointestinal symptoms by a questionnaire and measurement of proximal Stomach Function and per- ception by an electronic barostat and a standardized questionnaire. Nineteen obese patients had abnormal oesophageal acid exposure. The percentage of total time with pH <4 is significantly related to the presence of hiatal hernia, the oesophageal intensity-frequency symptom score and gender, i.e. higher percentage in men. The perception cumulative score was sig- nificantly different between patients with normal and abnormal oesophageal acid exposure after adjusting for covariates (gender, body mass index, age, minimal distending pressure, gastric tone and gastric com- pliance). Gastric tone and compliance were sig- nificantly related to the perception cumulative score. In conclusion, patients with abnormal oesophageal acid exposure have increased gastric perception. A significant relation among gastric tone, gastric com- pliance and upper gastrointestinal sensations was shown.
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Proximal Stomach Function in obesity with normal or abnormal oesophageal acid exposure
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 2006Co-Authors: Paola Iovino, Luigi Angrisani, Giuseppe Galloro, D. Consalvo, F. Tremolaterra, A. Pascariello, Carolina CiacciAbstract:There is an increased prevalence of gastro- oesophageal reflux and symptoms in obese patients. Information about the proximal Stomach in obese patients with reflux is lacking. Gastric volume and compliance are similar between obese and lean sub- jects. To study the proximal Stomach Function and perception in obese patients with normal or abnormal oesophageal acid exposure, thirty-one obese patients, with normal or abnormal oesophageal acid exposure, underwent medical evaluation of oesophageal and gastrointestinal symptoms by a questionnaire and measurement of proximal Stomach Function and per- ception by an electronic barostat and a standardized questionnaire. Nineteen obese patients had abnormal oesophageal acid exposure. The percentage of total time with pH
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Proximal Stomach Function in Systemic Sclerosis
Digestive Diseases and Sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
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Proximal Stomach Function in systemic sclerosis: relationship with autonomic nerve Function.
Digestive diseases and sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
Enrico Tirri - One of the best experts on this subject based on the ideXlab platform.
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Proximal Stomach Function in Systemic Sclerosis
Digestive Diseases and Sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
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Proximal Stomach Function in systemic sclerosis: relationship with autonomic nerve Function.
Digestive diseases and sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
Francesco Sabbatini - One of the best experts on this subject based on the ideXlab platform.
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Proximal Stomach Function in Systemic Sclerosis
Digestive Diseases and Sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
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Proximal Stomach Function in systemic sclerosis: relationship with autonomic nerve Function.
Digestive diseases and sciences, 2001Co-Authors: Paola Iovino, Gabriele Valentini, Carolina Ciacci, Amalia De Luca, Fabrizio Tremolaterra, Francesco Sabbatini, Enrico Tirri, Gabriele MazzaccaAbstract:Gastrointestinal involvement is frequent in patients with systemic sclerosis (SSc); however, studies on the proximal Stomach and its regulation are lacking. It has been hypothesized that the primary event in the pathogenesis of gastrointestinal involvement in SSc is an early neural lesion. This study investigates proximal Stomach Function and its relation to autonomic nerve Function in SSc. Twenty SSc patients classified in to clinical subsets, underwent measurement of proximal Stomach Function with and without glucagon by electronic barostat and an assessment of autonomic nerve Function. SSc patients were not significantly different from 11 controls for gastric compliance (59.5 ± 5.0 vs 47.7 ± 4.2 ml/mm Hg, P = 0.1). The pressure–volume curves in each participant with and without glucagon were significantly different (P < 0.001). A significant positive association was found between gastric compliance and autonomic nerve Function (P < 0.05). The change in gastric compliance during glucagon administration was significant associated with autonomic Function (P < 0.05). The perception cumulative scores did not differ between SSc patients and control subjects (P = 0.2). In conclusion, proximal Stomach Function is associated with autonomic nerve Function in SSc patients. This confirms the frequent association of motility disorders with autonomic dysFunction in SSc.
