The Experts below are selected from a list of 201 Experts worldwide ranked by ideXlab platform
Daniele Perucchini - One of the best experts on this subject based on the ideXlab platform.
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age effects on urethral Striated Muscle i changes in number and diameter of Striated Muscle fibers in the ventral urethra
American Journal of Obstetrics and Gynecology, 2002Co-Authors: Daniele Perucchini, U Peschers, John O L Delancey, James A Ashtonmiller, Tripti KatariaAbstract:Abstract OBJECTIVE: This study was undertaken to test the null hypothesis that the number of Striated Muscle fibers in the ventral wall of the female urethra remains constant with increasing age. STUDY DESIGN: The urethra and surrounding tissues from 25 female cadavers, mean age 52 years (±SD 18, range 15-80 years), were selected for this study. Each specimen was divided along the midsagittal plane, and a Masson trichrome histologic section was prepared. A systematic count of Striated Muscle fibers in the ventral wall was then obtained at each decile of urethral length. RESULTS: A decrease in the total number of fibers within the sampled area was found with increasing age. The mean of the total fibers across all urethrae was 17,423 (±SD 9,624, range 4,788-35,867). Over the life span, an average of 364 fibers (2%) were lost per year (95% CI 197-531; P 2 and decreased by 13 fibers/mm 2 per year (95% CI 8-17; P P =.3). CONCLUSIONS: The number and density of urethral Striated Muscle fibers decline with age. (Am J Obstet Gynecol 2002;186:351-5.)
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age effects on urethral Striated Muscle ii anatomic location of Muscle loss
American Journal of Obstetrics and Gynecology, 2002Co-Authors: Daniele Perucchini, John O L Delancey, James A Ashtonmiller, Andrzej T Galecki, Gabriel N SchaerAbstract:Abstract OBJECTIVE: The purpose of the study was to measure the thickness and cross-sectional area of urethral Muscle layers to identify localized Striated Muscle loss. STUDY DESIGN: The urethra and surrounding tissues from 25 female cadavers (mean age, 52 ± 18 [SD] years; range, 15-80 years) were used for this study. Axial and median sagittal histologic sections were prepared. Median sagittal Muscle layer thickness was measured every 10% of urethral length (each decile) in the dorsal wall (adjacent to the vagina) and ventral wall, beginning at the caudal margin of the detrusor Muscle (0%) and ending at the caudal margin of the Striated Muscle (100%). In the midurethral cross-section, the thickness of each layer was measured along radial lines placed every 45 degrees with 0 degrees at the ventral midline and 180 degrees at the dorsal midline. RESULTS: In the median sagittal sections, Striated Muscle layers of urethras were thinner at the vesical neck in older women. In the ventral wall, it decreased by a mean of 18 to 23 μm (3.4%-4.3%; P P 2 (3.8%) per year short ( P P CONCLUSION: Striated Muscle was lost at the bladder neck and along the dorsal wall of the urethra as women aged. (Am J Obstet Gynecol 2002;186:356-60.)
Tripti Kataria - One of the best experts on this subject based on the ideXlab platform.
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age effects on urethral Striated Muscle i changes in number and diameter of Striated Muscle fibers in the ventral urethra
American Journal of Obstetrics and Gynecology, 2002Co-Authors: Daniele Perucchini, U Peschers, John O L Delancey, James A Ashtonmiller, Tripti KatariaAbstract:Abstract OBJECTIVE: This study was undertaken to test the null hypothesis that the number of Striated Muscle fibers in the ventral wall of the female urethra remains constant with increasing age. STUDY DESIGN: The urethra and surrounding tissues from 25 female cadavers, mean age 52 years (±SD 18, range 15-80 years), were selected for this study. Each specimen was divided along the midsagittal plane, and a Masson trichrome histologic section was prepared. A systematic count of Striated Muscle fibers in the ventral wall was then obtained at each decile of urethral length. RESULTS: A decrease in the total number of fibers within the sampled area was found with increasing age. The mean of the total fibers across all urethrae was 17,423 (±SD 9,624, range 4,788-35,867). Over the life span, an average of 364 fibers (2%) were lost per year (95% CI 197-531; P 2 and decreased by 13 fibers/mm 2 per year (95% CI 8-17; P P =.3). CONCLUSIONS: The number and density of urethral Striated Muscle fibers decline with age. (Am J Obstet Gynecol 2002;186:351-5.)
Nikola Bursac - One of the best experts on this subject based on the ideXlab platform.
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Striated Muscle function, regeneration, and repair
Cellular and Molecular Life Sciences, 2016Co-Authors: I. Y. Shadrin, Alastair Khodabukus, Nikola BursacAbstract:As the only Striated Muscle tissues in the body, skeletal and cardiac Muscle share numerous structural and functional characteristics, while exhibiting vastly different size and regenerative potential. Healthy skeletal Muscle harbors a robust regenerative response that becomes inadequate after large Muscle loss or in degenerative pathologies and aging. In contrast, the mammalian heart loses its regenerative capacity shortly after birth, leaving it susceptible to permanent damage by acute injury or chronic disease. In this review, we compare and contrast the physiology and regenerative potential of native skeletal and cardiac Muscles, mechanisms underlying Striated Muscle dysfunction, and bioengineering strategies to treat Muscle disorders. We focus on different sources for cellular therapy, biomaterials to augment the endogenous regenerative response, and progress in engineering and application of mature Striated Muscle tissues in vitro and in vivo. Finally, we discuss the challenges and perspectives in translating Muscle bioengineering strategies to clinical practice.
James A Ashtonmiller - One of the best experts on this subject based on the ideXlab platform.
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age effects on urethral Striated Muscle i changes in number and diameter of Striated Muscle fibers in the ventral urethra
American Journal of Obstetrics and Gynecology, 2002Co-Authors: Daniele Perucchini, U Peschers, John O L Delancey, James A Ashtonmiller, Tripti KatariaAbstract:Abstract OBJECTIVE: This study was undertaken to test the null hypothesis that the number of Striated Muscle fibers in the ventral wall of the female urethra remains constant with increasing age. STUDY DESIGN: The urethra and surrounding tissues from 25 female cadavers, mean age 52 years (±SD 18, range 15-80 years), were selected for this study. Each specimen was divided along the midsagittal plane, and a Masson trichrome histologic section was prepared. A systematic count of Striated Muscle fibers in the ventral wall was then obtained at each decile of urethral length. RESULTS: A decrease in the total number of fibers within the sampled area was found with increasing age. The mean of the total fibers across all urethrae was 17,423 (±SD 9,624, range 4,788-35,867). Over the life span, an average of 364 fibers (2%) were lost per year (95% CI 197-531; P 2 and decreased by 13 fibers/mm 2 per year (95% CI 8-17; P P =.3). CONCLUSIONS: The number and density of urethral Striated Muscle fibers decline with age. (Am J Obstet Gynecol 2002;186:351-5.)
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age effects on urethral Striated Muscle ii anatomic location of Muscle loss
American Journal of Obstetrics and Gynecology, 2002Co-Authors: Daniele Perucchini, John O L Delancey, James A Ashtonmiller, Andrzej T Galecki, Gabriel N SchaerAbstract:Abstract OBJECTIVE: The purpose of the study was to measure the thickness and cross-sectional area of urethral Muscle layers to identify localized Striated Muscle loss. STUDY DESIGN: The urethra and surrounding tissues from 25 female cadavers (mean age, 52 ± 18 [SD] years; range, 15-80 years) were used for this study. Axial and median sagittal histologic sections were prepared. Median sagittal Muscle layer thickness was measured every 10% of urethral length (each decile) in the dorsal wall (adjacent to the vagina) and ventral wall, beginning at the caudal margin of the detrusor Muscle (0%) and ending at the caudal margin of the Striated Muscle (100%). In the midurethral cross-section, the thickness of each layer was measured along radial lines placed every 45 degrees with 0 degrees at the ventral midline and 180 degrees at the dorsal midline. RESULTS: In the median sagittal sections, Striated Muscle layers of urethras were thinner at the vesical neck in older women. In the ventral wall, it decreased by a mean of 18 to 23 μm (3.4%-4.3%; P P 2 (3.8%) per year short ( P P CONCLUSION: Striated Muscle was lost at the bladder neck and along the dorsal wall of the urethra as women aged. (Am J Obstet Gynecol 2002;186:356-60.)
John O L Delancey - One of the best experts on this subject based on the ideXlab platform.
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age effects on urethral Striated Muscle i changes in number and diameter of Striated Muscle fibers in the ventral urethra
American Journal of Obstetrics and Gynecology, 2002Co-Authors: Daniele Perucchini, U Peschers, John O L Delancey, James A Ashtonmiller, Tripti KatariaAbstract:Abstract OBJECTIVE: This study was undertaken to test the null hypothesis that the number of Striated Muscle fibers in the ventral wall of the female urethra remains constant with increasing age. STUDY DESIGN: The urethra and surrounding tissues from 25 female cadavers, mean age 52 years (±SD 18, range 15-80 years), were selected for this study. Each specimen was divided along the midsagittal plane, and a Masson trichrome histologic section was prepared. A systematic count of Striated Muscle fibers in the ventral wall was then obtained at each decile of urethral length. RESULTS: A decrease in the total number of fibers within the sampled area was found with increasing age. The mean of the total fibers across all urethrae was 17,423 (±SD 9,624, range 4,788-35,867). Over the life span, an average of 364 fibers (2%) were lost per year (95% CI 197-531; P 2 and decreased by 13 fibers/mm 2 per year (95% CI 8-17; P P =.3). CONCLUSIONS: The number and density of urethral Striated Muscle fibers decline with age. (Am J Obstet Gynecol 2002;186:351-5.)
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age effects on urethral Striated Muscle ii anatomic location of Muscle loss
American Journal of Obstetrics and Gynecology, 2002Co-Authors: Daniele Perucchini, John O L Delancey, James A Ashtonmiller, Andrzej T Galecki, Gabriel N SchaerAbstract:Abstract OBJECTIVE: The purpose of the study was to measure the thickness and cross-sectional area of urethral Muscle layers to identify localized Striated Muscle loss. STUDY DESIGN: The urethra and surrounding tissues from 25 female cadavers (mean age, 52 ± 18 [SD] years; range, 15-80 years) were used for this study. Axial and median sagittal histologic sections were prepared. Median sagittal Muscle layer thickness was measured every 10% of urethral length (each decile) in the dorsal wall (adjacent to the vagina) and ventral wall, beginning at the caudal margin of the detrusor Muscle (0%) and ending at the caudal margin of the Striated Muscle (100%). In the midurethral cross-section, the thickness of each layer was measured along radial lines placed every 45 degrees with 0 degrees at the ventral midline and 180 degrees at the dorsal midline. RESULTS: In the median sagittal sections, Striated Muscle layers of urethras were thinner at the vesical neck in older women. In the ventral wall, it decreased by a mean of 18 to 23 μm (3.4%-4.3%; P P 2 (3.8%) per year short ( P P CONCLUSION: Striated Muscle was lost at the bladder neck and along the dorsal wall of the urethra as women aged. (Am J Obstet Gynecol 2002;186:356-60.)
