The Experts below are selected from a list of 120 Experts worldwide ranked by ideXlab platform
Robert J. Nash - One of the best experts on this subject based on the ideXlab platform.
-
Lignans from Strophanthus gratus.
Fitoterapia, 2001Co-Authors: Sally Cowan, Michael Stewart, D.k. Abbiw, Zahid Latif, Satyajit D. Sarker, Robert J. NashAbstract:Three lignans, pinoresinol (1), 8-hydroxypinoresinol (2) and olivil (3) have been isolated from the leaves of Strophanthus gratus by reversed-phase HPLC.
Sally Cowan - One of the best experts on this subject based on the ideXlab platform.
-
Lignans from Strophanthus gratus.
Fitoterapia, 2001Co-Authors: Sally Cowan, Michael Stewart, D.k. Abbiw, Zahid Latif, Satyajit D. Sarker, Robert J. NashAbstract:Three lignans, pinoresinol (1), 8-hydroxypinoresinol (2) and olivil (3) have been isolated from the leaves of Strophanthus gratus by reversed-phase HPLC.
Fageyinbo Muyiwa Samuel - One of the best experts on this subject based on the ideXlab platform.
-
Anti-Nociceptive Activity of Fractionated Root Extract of Strophanthus hispidus DC (Apocynaceae)
Journal of Natural Remedies, 2014Co-Authors: Agbaje Esther Oluwatoyin, Fageyinbo Muyiwa SamuelAbstract:Strophanthus hispidus DC belongs to the family of plants known as Apocynaceae, they are popularly known as poison arrow vine, brown Strophanthus and hairy Strophanthus in western part of Africa including Nigeria. This study investigated the anti-nociceptive property of ethyl acetate, n-butanol and aqueous fractions of the root extract of Strophanthus hispidus DC (Apocynaceae) in rodents of both sexes. The fractions, at a dose of 200 mg/kg each were given via oral route to the animals used in the various models-acetic acid-induced mouse writhing test, formalin- induced pain, Haffner's tail clip test, hot plate-induced pain and tail immersion test. In each of the models, the ethyl acetate fraction, n-butanol fraction and aqueous fraction of Strophanthus hispidus each possesses a significant (P
-
anti nociceptive activity of fractionated root extract of Strophanthus hispidus dc apocynaceae
Journal of Natural Remedies, 2014Co-Authors: Agbaje Esther Oluwatoyin, Fageyinbo Muyiwa SamuelAbstract:Strophanthus hispidus DC belongs to the family of plants known as Apocynaceae, they are popularly known as poison arrow vine, brown Strophanthus and hairy Strophanthus in western part of Africa including Nigeria. This study investigated the anti-nociceptive property of ethyl acetate, n-butanol and aqueous fractions of the root extract of Strophanthus hispidus DC (Apocynaceae) in rodents of both sexes. The fractions, at a dose of 200 mg/kg each were given via oral route to the animals used in the various models-acetic acid-induced mouse writhing test, formalin- induced pain, Haffner's tail clip test, hot plate-induced pain and tail immersion test. In each of the models, the ethyl acetate fraction, n-butanol fraction and aqueous fraction of Strophanthus hispidus each possesses a significant (P<0.05, P<0.01, P<0.001) anti-nociceptive effect. The anti-nociceptive activity of the fractions was mediated through central and peripheral mechanism. The effect of the extract was comparable to that produced by peripheral analgesics the NSAIDs (aspirin) and centrally acting analgesic opioids (morphine) used as positive control in the various models employed. Phytochemical analysis of the fractions indicated the presence of flavonoids, cardiac glycosides, tannins, alkaloids and anthraquinones which also contributed to the anti-nociceptive activity of the extract. These findings showed the plant as a novel therapy for pain.
Karl P. Skari - One of the best experts on this subject based on the ideXlab platform.
-
The effect on blood clotting of some west African plants used against snakebite
Journal of ethnopharmacology, 1994Co-Authors: Peter J. Houghton, Karl P. SkariAbstract:Aqueous extracts of the bark of Schumanniophyton magnificum and the leaves of Mucuna pruriens var. utilis, Strophanthus gratus and Strophanthus hispidus show a dose related ability to prolong the time taken to clot for blood treated with a standardised dose of the venom of Echis carinatus. Strophanthus hispidus was shown to be the most potent of the plants tested. The dose-response profiles obtained showed that the increased clotting time was due to different processes for the different plant extracts.
Kiichiro Kawaguchi - One of the best experts on this subject based on the ideXlab platform.
-
Cardenolides in the regenerated plants obtained from Strophanthus divaricatus calli
Phytochemistry, 1993Co-Authors: Kiichiro Kawaguchi, Masao Hirotani, Tsutomu Furuya, Isao Asaka, Shigeki KatsukiAbstract:Abstract The regenerated plants obtained from Strophanthus divaricatus calli contain 10 cardenolides, accumulating seven of them in the original plants. At
-
Strophanthus Species (Members of the Dogbane Family): In Vitro Culture and the Production of Cardenolides
Medicinal and Aromatic Plants IV, 1993Co-Authors: Kiichiro Kawaguchi, Masao Hirotani, Tsutomu FuruyaAbstract:The cardiac glycosides are pharmaceutically potential drug groups that are available to medicine today for the treatment of congestive heart failure. Clinically availabilities are derived from the leaves and seeds of plant in the genera Digitalis and Strophanthus. In vitro culture, regeneration, and production of Digitalis (foxglove) cardenolides and other secondary metabolites were reviewed in detail (Rucker 1988).
