Structural Separation

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Roberto Nicoletti - One of the best experts on this subject based on the ideXlab platform.

  • simon like and functional affordance effects with tools the effects of object perceptual discrimination and object action state
    Quarterly Journal of Experimental Psychology, 2010
    Co-Authors: Antonello Pellicano, Anna M. Borghi, Sandro Rubichi, Cristina Iani, Roberto Nicoletti
    Abstract:

    In the present study two separate stimulus–response compatibility effects (functional affordance and Simon-like effects) were investigated with centrally presented pictures of an object tool (a torch) characterized by a Structural Separation between the graspable portion and the goal-directed portion. In Experiment 1, participants were required to decide whether the torch was red or blue, while in Experiment 2 they were required to decide whether the torch was upright or inverted. Our results showed that with the same stimulus two types of compatibility effect emerged: one based on the direction signalled by the goal-directed portion of the tool (a Simon-like effect as observed in Experiment 1), and the other based on the actions associated with an object (a functional affordance effect as observed in Experiment 2). Both effects emerged independently of the person's intention to act on the stimulus, but depended on the stimulus properties that were processed in order to perform the task.

  • simon like and functional affordance effects with tools the effects of object perceptual discrimination and object action state
    Quarterly Journal of Experimental Psychology, 2010
    Co-Authors: Antonello Pellicano, Anna M. Borghi, Sandro Rubichi, Cristina Iani, Roberto Nicoletti
    Abstract:

    In the present study two separate stimulus–response compatibility effects (functional affordance and Simon-like effects) were investigated with centrally presented pictures of an object tool (a torch) characterized by a Structural Separation between the graspable portion and the goal-directed portion. In Experiment 1, participants were required to decide whether the torch was red or blue, while in Experiment 2 they were required to decide whether the torch was upright or inverted. Our results showed that with the same stimulus two types of compatibility effect emerged: one based on the direction signalled by the goal-directed portion of the tool (a Simon-like effect as observed in Experiment 1), and the other based on the actions associated with an object (a functional affordance effect as observed in Experiment 2). Both effects emerged independently of the person's intention to act on the stimulus, but depended on the stimulus properties that were processed in order to perform the task.

Antonello Pellicano - One of the best experts on this subject based on the ideXlab platform.

  • simon like and functional affordance effects with tools the effects of object perceptual discrimination and object action state
    Quarterly Journal of Experimental Psychology, 2010
    Co-Authors: Antonello Pellicano, Anna M. Borghi, Sandro Rubichi, Cristina Iani, Roberto Nicoletti
    Abstract:

    In the present study two separate stimulus–response compatibility effects (functional affordance and Simon-like effects) were investigated with centrally presented pictures of an object tool (a torch) characterized by a Structural Separation between the graspable portion and the goal-directed portion. In Experiment 1, participants were required to decide whether the torch was red or blue, while in Experiment 2 they were required to decide whether the torch was upright or inverted. Our results showed that with the same stimulus two types of compatibility effect emerged: one based on the direction signalled by the goal-directed portion of the tool (a Simon-like effect as observed in Experiment 1), and the other based on the actions associated with an object (a functional affordance effect as observed in Experiment 2). Both effects emerged independently of the person's intention to act on the stimulus, but depended on the stimulus properties that were processed in order to perform the task.

  • simon like and functional affordance effects with tools the effects of object perceptual discrimination and object action state
    Quarterly Journal of Experimental Psychology, 2010
    Co-Authors: Antonello Pellicano, Anna M. Borghi, Sandro Rubichi, Cristina Iani, Roberto Nicoletti
    Abstract:

    In the present study two separate stimulus–response compatibility effects (functional affordance and Simon-like effects) were investigated with centrally presented pictures of an object tool (a torch) characterized by a Structural Separation between the graspable portion and the goal-directed portion. In Experiment 1, participants were required to decide whether the torch was red or blue, while in Experiment 2 they were required to decide whether the torch was upright or inverted. Our results showed that with the same stimulus two types of compatibility effect emerged: one based on the direction signalled by the goal-directed portion of the tool (a Simon-like effect as observed in Experiment 1), and the other based on the actions associated with an object (a functional affordance effect as observed in Experiment 2). Both effects emerged independently of the person's intention to act on the stimulus, but depended on the stimulus properties that were processed in order to perform the task.

Anton P J Middelberg - One of the best experts on this subject based on the ideXlab platform.

  • synthetic biology design to display an 18 kda rotavirus large antigen on a modular virus like particle
    Vaccine, 2015
    Co-Authors: Linda H L Lua, Yuanyuan Fan, Cindy Chang, Natalie K Connors, Anton P J Middelberg
    Abstract:

    Virus-like particles are an established class of commercial vaccine possessing excellent function and proven stability. Exciting developments made possible by modern tools of synthetic biology has stimulated emergence of modular VLPs, whereby parts of one pathogen are by design integrated into a less harmful VLP which has preferential physical and manufacturing character. This strategy allows the immunologically protective parts of a pathogen to be displayed on the most-suitable VLP. However, the field of modular VLP design is immature, and robust design principles are yet to emerge, particularly for larger antigenic structures. Here we use a combination of molecular dynamic simulation and experiment to reveal two key design principles for VLPs. First, the linkers connecting the integrated antigenic module with the VLP-forming protein must be well designed to ensure Structural Separation and independence. Second, the number of antigenic domains on the VLP surface must be sufficiently below the maximum such that a "steric barrier" to VLP formation cannot exist. This second principle leads to designs whereby co-expression of modular protein with unmodified VLP-forming protein can titrate down the amount of antigen on the surface of the VLP, to the point where assembly can proceed. In this work we elucidate these principles by displaying the 18.1 kDa VP8* domain from rotavirus on the murine polyomavirus VLP, and show functional presentation of the antigenic structure.

Anna M. Borghi - One of the best experts on this subject based on the ideXlab platform.

  • simon like and functional affordance effects with tools the effects of object perceptual discrimination and object action state
    Quarterly Journal of Experimental Psychology, 2010
    Co-Authors: Antonello Pellicano, Anna M. Borghi, Sandro Rubichi, Cristina Iani, Roberto Nicoletti
    Abstract:

    In the present study two separate stimulus–response compatibility effects (functional affordance and Simon-like effects) were investigated with centrally presented pictures of an object tool (a torch) characterized by a Structural Separation between the graspable portion and the goal-directed portion. In Experiment 1, participants were required to decide whether the torch was red or blue, while in Experiment 2 they were required to decide whether the torch was upright or inverted. Our results showed that with the same stimulus two types of compatibility effect emerged: one based on the direction signalled by the goal-directed portion of the tool (a Simon-like effect as observed in Experiment 1), and the other based on the actions associated with an object (a functional affordance effect as observed in Experiment 2). Both effects emerged independently of the person's intention to act on the stimulus, but depended on the stimulus properties that were processed in order to perform the task.

  • simon like and functional affordance effects with tools the effects of object perceptual discrimination and object action state
    Quarterly Journal of Experimental Psychology, 2010
    Co-Authors: Antonello Pellicano, Anna M. Borghi, Sandro Rubichi, Cristina Iani, Roberto Nicoletti
    Abstract:

    In the present study two separate stimulus–response compatibility effects (functional affordance and Simon-like effects) were investigated with centrally presented pictures of an object tool (a torch) characterized by a Structural Separation between the graspable portion and the goal-directed portion. In Experiment 1, participants were required to decide whether the torch was red or blue, while in Experiment 2 they were required to decide whether the torch was upright or inverted. Our results showed that with the same stimulus two types of compatibility effect emerged: one based on the direction signalled by the goal-directed portion of the tool (a Simon-like effect as observed in Experiment 1), and the other based on the actions associated with an object (a functional affordance effect as observed in Experiment 2). Both effects emerged independently of the person's intention to act on the stimulus, but depended on the stimulus properties that were processed in order to perform the task.

Sandro Rubichi - One of the best experts on this subject based on the ideXlab platform.

  • simon like and functional affordance effects with tools the effects of object perceptual discrimination and object action state
    Quarterly Journal of Experimental Psychology, 2010
    Co-Authors: Antonello Pellicano, Anna M. Borghi, Sandro Rubichi, Cristina Iani, Roberto Nicoletti
    Abstract:

    In the present study two separate stimulus–response compatibility effects (functional affordance and Simon-like effects) were investigated with centrally presented pictures of an object tool (a torch) characterized by a Structural Separation between the graspable portion and the goal-directed portion. In Experiment 1, participants were required to decide whether the torch was red or blue, while in Experiment 2 they were required to decide whether the torch was upright or inverted. Our results showed that with the same stimulus two types of compatibility effect emerged: one based on the direction signalled by the goal-directed portion of the tool (a Simon-like effect as observed in Experiment 1), and the other based on the actions associated with an object (a functional affordance effect as observed in Experiment 2). Both effects emerged independently of the person's intention to act on the stimulus, but depended on the stimulus properties that were processed in order to perform the task.

  • simon like and functional affordance effects with tools the effects of object perceptual discrimination and object action state
    Quarterly Journal of Experimental Psychology, 2010
    Co-Authors: Antonello Pellicano, Anna M. Borghi, Sandro Rubichi, Cristina Iani, Roberto Nicoletti
    Abstract:

    In the present study two separate stimulus–response compatibility effects (functional affordance and Simon-like effects) were investigated with centrally presented pictures of an object tool (a torch) characterized by a Structural Separation between the graspable portion and the goal-directed portion. In Experiment 1, participants were required to decide whether the torch was red or blue, while in Experiment 2 they were required to decide whether the torch was upright or inverted. Our results showed that with the same stimulus two types of compatibility effect emerged: one based on the direction signalled by the goal-directed portion of the tool (a Simon-like effect as observed in Experiment 1), and the other based on the actions associated with an object (a functional affordance effect as observed in Experiment 2). Both effects emerged independently of the person's intention to act on the stimulus, but depended on the stimulus properties that were processed in order to perform the task.