The Experts below are selected from a list of 2058 Experts worldwide ranked by ideXlab platform
Arati Bhatia - One of the best experts on this subject based on the ideXlab platform.
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fine needle aspiration diagnosis of a Subcutaneous Abscess from enterobius vermicularis infestation
Acta Cytologica, 1997Co-Authors: Vinod K Arora, Navjeevan Singh, Sujata Chaturvedi, Arati BhatiaAbstract:BACKGROUND: Extraintestinal infestation by Enterobius vermicularis is uncommon. It has been reported to occur in the peritoneal cavity, ovary, fallopian tube, endometrium, lung, liver and urinary tract. CASE REPORT: Fine needle aspiration diagnosis was made in a case of enterobiasis presenting with a Subcutaneous Abscess in the natal cleft. Eggs, as well as fragments of cuticle of the adult worm, were found; the morphology of both was best visualized in Papanicolaou-stained smears. Polarizing microscopy highlighted the equally spaced parallel grooves of the cuticle. CONCLUSION: Fine needle aspiration cytology of Subcutaneous Abscesses due to enterobiasis can be diagnostic when eggs, or eggs with cuticle, are identified in a suppurative or granulomatous inflammation.
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fine needle aspiration diagnosis of a Subcutaneous Abscess from enterobius vermicularis infestation a case report
Acta Cytologica, 1997Co-Authors: Vinod K Arora, Navjeevan Singh, Sujata Chaturvedi, Arati BhatiaAbstract:Background Extraintestinal infestation by Enterobius vermicularis is uncommon. It has been reported to occur in the peritoneal cavity, ovary, fallopian tube, endometrium, lung, liver and urinary tract. Case report Fine needle aspiration diagnosis was made in a case of enterobiasis presenting with a Subcutaneous Abscess in the natal cleft. Eggs, as well as fragments of cuticle of the adult worm, were found; the morphology of both was best visualized in Papanicolaou-stained smears. Polarizing microscopy highlighted the equally spaced parallel grooves of the cuticle. Conclusion Fine needle aspiration cytology of Subcutaneous Abscesses due to enterobiasis can be diagnostic when eggs, or eggs with cuticle, are identified in a suppurative or granulomatous inflammation.
Noriko Hasegawa - One of the best experts on this subject based on the ideXlab platform.
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characterization of the pathogenicity of streptococcus intermedius tyg1620 isolated from a human brain Abscess based on the complete genome sequence with transcriptome analysis and transposon mutagenesis in a murine Subcutaneous Abscess model
Infection and Immunity, 2017Co-Authors: Noriko Hasegawa, Tsuyoshi Sekizuka, Yutaka Sugi, Nobuhiro Kawakami, Yumiko Ogasawara, Kengo Kato, Akifumi Yamashita, Fumihiko Takeuchi, Makoto KurodaAbstract:Streptococcus intermedius is known to cause periodontitis and pyogenic infections in the brain and liver. Here we report the complete genome sequence of strain TYG1620 (genome size, 2,006,877 bp; GC content, 37.6%; 2,020 predicted open reading frames [ORFs]) isolated from a brain Abscess in an infant. Comparative analysis of S. intermedius genome sequences suggested that TYG1620 carries a notable type VII secretion system (T7SS), two long repeat regions, and 19 ORFs for cell wall-anchored proteins (CWAPs). To elucidate the genes responsible for the pathogenicity of TYG1620, transcriptome analysis was performed in a murine Subcutaneous Abscess model. The results suggest that the levels of expression of small hypothetical proteins similar to phenol-soluble modulin β1 (PSMβ1), a staphylococcal virulence factor, significantly increased in the Abscess model. In addition, an experiment in a murine Subcutaneous Abscess model with random transposon (Tn) mutant attenuation suggested that Tn mutants with mutations in 212 ORFs in the Tn mutant library were attenuated in the murine Abscess model (629 ORFs were disrupted in total); the 212 ORFs are putatively essential for Abscess formation. Transcriptome analysis identified 37 ORFs, including paralogs of the T7SS and a putative glucan-binding CWAP in long repeat regions, to be upregulated and attenuated in vivo This study provides a comprehensive characterization of S. intermedius pathogenicity based on the complete genome sequence and a murine Subcutaneous Abscess model with transcriptome and Tn mutagenesis, leading to the identification of pivotal targets for vaccines or antimicrobial agents for the control of S. intermedius infections.
Vinod K Arora - One of the best experts on this subject based on the ideXlab platform.
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fine needle aspiration diagnosis of a Subcutaneous Abscess from enterobius vermicularis infestation
Acta Cytologica, 1997Co-Authors: Vinod K Arora, Navjeevan Singh, Sujata Chaturvedi, Arati BhatiaAbstract:BACKGROUND: Extraintestinal infestation by Enterobius vermicularis is uncommon. It has been reported to occur in the peritoneal cavity, ovary, fallopian tube, endometrium, lung, liver and urinary tract. CASE REPORT: Fine needle aspiration diagnosis was made in a case of enterobiasis presenting with a Subcutaneous Abscess in the natal cleft. Eggs, as well as fragments of cuticle of the adult worm, were found; the morphology of both was best visualized in Papanicolaou-stained smears. Polarizing microscopy highlighted the equally spaced parallel grooves of the cuticle. CONCLUSION: Fine needle aspiration cytology of Subcutaneous Abscesses due to enterobiasis can be diagnostic when eggs, or eggs with cuticle, are identified in a suppurative or granulomatous inflammation.
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fine needle aspiration diagnosis of a Subcutaneous Abscess from enterobius vermicularis infestation a case report
Acta Cytologica, 1997Co-Authors: Vinod K Arora, Navjeevan Singh, Sujata Chaturvedi, Arati BhatiaAbstract:Background Extraintestinal infestation by Enterobius vermicularis is uncommon. It has been reported to occur in the peritoneal cavity, ovary, fallopian tube, endometrium, lung, liver and urinary tract. Case report Fine needle aspiration diagnosis was made in a case of enterobiasis presenting with a Subcutaneous Abscess in the natal cleft. Eggs, as well as fragments of cuticle of the adult worm, were found; the morphology of both was best visualized in Papanicolaou-stained smears. Polarizing microscopy highlighted the equally spaced parallel grooves of the cuticle. Conclusion Fine needle aspiration cytology of Subcutaneous Abscesses due to enterobiasis can be diagnostic when eggs, or eggs with cuticle, are identified in a suppurative or granulomatous inflammation.
Takahiro Takazono - One of the best experts on this subject based on the ideXlab platform.
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munchausen syndrome mimicking refractory Subcutaneous Abscess with bacteremia diagnosed by repetitive element sequence based polymerase chain reaction a case report
Journal of Medical Case Reports, 2019Co-Authors: Naoki Iwanaga, Kazuko Yamamoto, Takahiro Takazono, Tomomi Saijo, Yoshifumi Imamura, Taiga Miyazaki, Koichi Izumikawa, Yoshihiro Yamamoto, Katsunori Yanagihara, Akira YasuokaAbstract:Rapid diagnosis and appropriate treatment of Munchausen syndrome is important not only for the patient but also for health care workers because a delay in diagnosis can worsen patients’ clinical outcomes, and result in a substantial medical cost. A young and previously healthy 24-year-old Japanese woman, a nurse, presented with complaints of refractory Abscess on her left upper limb for 3 months. A physical examination on admission revealed low-grade fever and a Subcutaneous Abscess in her left forearm. Laboratory data suggested mild systemic inflammation and liver dysfunction, but no abnormalities of the immune system, including changes in the number of lymphocytes and neutrophils, neutrophil phagocytic capacity, and natural killer (NK) cell activity, were observed. A human immunodeficiency virus test was also negative. Multiple modalities, including positron emission tomography-computed tomography, failed to detect any cause and focus of infection except her left upper limb. Streptococcus mitis and Prevotella buccae were detected from the wound, but no microorganisms were detected in a blood culture. The cellulitis promptly resolved; however, exacerbation of the Subcutaneous Abscess with polymicrobial bacteremia repeatedly occurred unexpectedly. Because of this puzzling clinical course, the possibility of self-injury was finally suspected. Three syringes with needles, with a turbid liquid, were found in our patient’s bag. Enterobacter cloacae and Enterococcus faecalis were detected in the liquid, and an analysis via repetitive element sequence-based polymerase chain reaction determined that Enterococcus faecalis in the wound and syringe contents were genetically identical. She was diagnosed as having Munchausen syndrome and treated with the collaboration of a psychiatrist. She finally confessed that she had injected her own saliva and toilet water into the drip line and wound. This case report is valuable in that it is the first case in which this syndrome was diagnosed by a genetic method. Munchausen syndrome should not be neglected as a possible cause of refractory and recurrent infection.
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paradoxical response to disseminated non tuberculosis mycobacteriosis treatment in a patient receiving tumor necrosis factor α inhibitor a case report
BMC Infectious Diseases, 2014Co-Authors: Takahiro Takazono, Yoshifumi Imamura, Taiga Miyazaki, Koichi Izumikawa, Katsunori Yanagihara, Shigeki Nakamura, Hiroshi Kakeya, Shigeru KohnoAbstract:Background: Biological agents such as tumor necrosis factor-α inhibitors are known to cause mycobacterium infections. Here, we report a disseminated non-tuberculosis case caused by TNF-α inhibitor therapy and a probable paradoxical response to antimycobacterial therapy. Case presentation: A 68-year-old man with relapsing polychondritis was refractory to glucocorticoid therapy; adalimumab was therefore administered in combination with oral glucocorticoids. Treatment with 40 mg of adalimumab led to rapid improvement of his clinical manifestations. The administration of tacrolimus (1 mg) was started as the dosage of oral glucocorticoids was tapered. However, the patient developed an intermittent high fever and productive cough 15 months after starting adalimumab treatment. A chest computed tomography scan revealed new granular shadows and multiple nodules in both lung fields with mediastinal lymphadenopathy, and Mycobacterium intracellulare was isolated from 2 sputum samples; based on these findings, the patient was diagnosed with non-tuberculosis mycobacteriosis. Tacrolimus treatment was discontinued and oral clarithromycin (800 mg/day), rifampicin (450 mg/day), and ethambutol (750 mg/day) treatment was initiated. However, his condition continued to deteriorate despite 4 months of treatment; moreover, paravertebral and Subcutaneous Abscesses developed and increased the size of the mediastinal lymphadenopathy. Biopsy of the mediastinal lymphadenopathy and a Subcutaneous Abscess of the right posterior thigh indicated the presence of Mycobacterium avium complex (MAC), and the diagnosis of disseminated non-tuberculosis mycobacteriosis was confirmed. Despite 9 months of antimycobacterial therapy, the mediastinal lymphadenopathy and paravertebral and Subcutaneous Abscesses had enlarged and additional Subcutaneous Abscesses had developed, although microscopic examinations and cultures of sputum and Subcutaneous Abscess samples yielded negative results. We considered this a paradoxical reaction similar to other reports in tuberculosis patients who had discontinued biological agent treatments, and increased the dose of oral glucocorticoids. The patient’s symptoms gradually improved with this increased dose and his lymph nodes and Abscesses began to decrease in size. (Continued on next page)
Ravindra K Vegunta - One of the best experts on this subject based on the ideXlab platform.
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incision and loop drainage a minimally invasive technique for Subcutaneous Abscess management in children
Journal of Pediatric Surgery, 2010Co-Authors: Steven S Tsoraides, Richard H Pearl, Amy B Stanfill, Lizabeth J Wallace, Ravindra K VeguntaAbstract:Abstract Purpose The aim of the study was to evaluate outcomes after a minimally invasive approach to pediatric Subcutaneous Abscess management as a replacement for wide exposure, debridement, and repetitive packing. Methods A retrospective study was performed of all children who underwent incision and loop drainage for Subcutaneous Abscesses between January 2002 and October 2007 at our institution. Technique Two mini incisions, 4-5 mm each, were made on the Abscess, as far apart as possible. Abscess was probed, and pus was drained. Abscess was irrigated with normal saline; a loop drain was passed through one incision, brought out through the other, and tied to itself. An absorbent dressing was applied over the loop and changed regularly. Results One hundred fifteen patients underwent drainage procedures as described; 5 patients had multiple Abscesses. Mean values (range) are as follows: age, 4.25 years (19 days to 20.5 years); duration of symptoms, 7.8 days (1-42 days); length of hospital stay, 3 days (1-39 days); duration of procedure, 10.8 minutes (4-43 minutes); drain duration, 10.4 days (3-24 days); and number of postoperative visits, 1.8 (1-17). Bacterial culture data were available for 101 patients. Of these, 50% had methicillin-resistant Staphylococcus aureus , 26% had methicillin-sensitive Staphylococcus aureus , and 9% streptococcal species. Of the 115 patients, 5 had pilonidal Abscesses, 1 required reoperation for persistent drainage, and 1 had a planned staged excision. Of the remaining 110 patients, 6 (5.5%) required reoperation—4 with loop drains and 2 with incision and packing with complete healing. Conclusion The use of loop drains proved safe and effective in the treatment of Subcutaneous Abscesses in children. Eliminating the need for repetitive and cumbersome wound packing simplifies postoperative wound care. Furthermore, there is an expected cost savings with this technique given the decreased need for wound care materials and professional postoperative home health services. We recommend this minimally invasive technique as the treatment of choice for Subcutaneous Abscesses in children and consider it the standard of care in our facility.
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incision and loop drainage a minimally invasive technique for Subcutaneous Abscess management in children
Journal of Pediatric Surgery, 2010Co-Authors: Steven S Tsoraides, Richard H Pearl, Amy B Stanfill, Lizabeth J Wallace, Ravindra K VeguntaAbstract:Abstract Purpose The aim of the study was to evaluate outcomes after a minimally invasive approach to pediatric Subcutaneous Abscess management as a replacement for wide exposure, debridement, and repetitive packing. Methods A retrospective study was performed of all children who underwent incision and loop drainage for Subcutaneous Abscesses between January 2002 and October 2007 at our institution. Technique Two mini incisions, 4-5 mm each, were made on the Abscess, as far apart as possible. Abscess was probed, and pus was drained. Abscess was irrigated with normal saline; a loop drain was passed through one incision, brought out through the other, and tied to itself. An absorbent dressing was applied over the loop and changed regularly. Results One hundred fifteen patients underwent drainage procedures as described; 5 patients had multiple Abscesses. Mean values (range) are as follows: age, 4.25 years (19 days to 20.5 years); duration of symptoms, 7.8 days (1-42 days); length of hospital stay, 3 days (1-39 days); duration of procedure, 10.8 minutes (4-43 minutes); drain duration, 10.4 days (3-24 days); and number of postoperative visits, 1.8 (1-17). Bacterial culture data were available for 101 patients. Of these, 50% had methicillin-resistant Staphylococcus aureus , 26% had methicillin-sensitive Staphylococcus aureus , and 9% streptococcal species. Of the 115 patients, 5 had pilonidal Abscesses, 1 required reoperation for persistent drainage, and 1 had a planned staged excision. Of the remaining 110 patients, 6 (5.5%) required reoperation—4 with loop drains and 2 with incision and packing with complete healing. Conclusion The use of loop drains proved safe and effective in the treatment of Subcutaneous Abscesses in children. Eliminating the need for repetitive and cumbersome wound packing simplifies postoperative wound care. Furthermore, there is an expected cost savings with this technique given the decreased need for wound care materials and professional postoperative home health services. We recommend this minimally invasive technique as the treatment of choice for Subcutaneous Abscesses in children and consider it the standard of care in our facility.
