The Experts below are selected from a list of 624 Experts worldwide ranked by ideXlab platform
Joon Koo Han - One of the best experts on this subject based on the ideXlab platform.
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No-touch radiofrequency ablation using multiple electrodes: An in vivo comparison study of switching monopolar versus switching bipolar modes in porcine livers - Fig 5
2017Co-Authors: Won Chang, Jeong Min Lee, Jeong Hee Yoon, Dong Ho Lee, Sang Min Lee, Kyoung Bun Lee, Bo Ram Kim, Tae-hyung Kim, Seunghyun Lee, Joon Koo HanAbstract:(a) Photograph shows discolored thickened whitish area of the stomach suggesting thermal injury. (b) (c) Corresponding stomach specimen with hematoxylin and eosin staining (H&E) shows thermal injury to the mucosa. Focal mucosal necrosis is present in (b) (arrow) (x40), and myxoid degeneration of serosa, Subserosa and proper muscle with dilated lymphatic channels, and fluid accumulation in Subserosa are present in (c) (arrow) (x40). (d) Photograph shows the H&E stained stomach specimen without thermal injury (x12.5).
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No-touch radiofrequency ablation using multiple electrodes: An in vivo comparison study of switching monopolar versus switching bipolar modes in porcine livers - Fig 7
2017Co-Authors: Won Chang, Jeong Min Lee, Jeong Hee Yoon, Dong Ho Lee, Sang Min Lee, Kyoung Bun Lee, Bo Ram Kim, Tae-hyung Kim, Seunghyun Lee, Joon Koo HanAbstract:(a) Photograph shows discolored thickened whitish area of the small bowel suggesting thermal injury. (b) (c) Corresponding small bowel specimen with hematoxylin and eosin staining (H&E) shows thermal injury to the mucosa. Mucosal ulceration was noted in (b) (arrow) (x100). Chronic active inflammation in serosa and Subserosa with focal necrosis are present in (c) (arrow) (x100). (d) Photograph shows the H&E stained small bowel specimen without thermal injury (x100).
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No-touch radiofrequency ablation using multiple electrodes: An in vivo comparison study of switching monopolar versus switching bipolar modes in porcine livers - Fig 6
2017Co-Authors: Won Chang, Jeong Min Lee, Jeong Hee Yoon, Dong Ho Lee, Sang Min Lee, Kyoung Bun Lee, Bo Ram Kim, Tae-hyung Kim, Seunghyun Lee, Joon Koo HanAbstract:(a) Photograph shows the whitish area of the gall bladder suggesting thermal injury (arrow). (b) (c) Corresponding gall bladder specimen and adjacent liver parenchyma with hematoxylin and eosin staining (H&E) show thermal injury to the mucosa. Mucosal and submucosal damage are evident. Lymphatic dilatation of Subserosa is noted in (b) (circle) (x12.5). The mucosal epithelium is replaced by dense fibrosis in (c) (arrow) (x100). (d) Photograph shows the H&E stained gall bladder specimen without thermal injury (x100).
Won Chang - One of the best experts on this subject based on the ideXlab platform.
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No-touch radiofrequency ablation using multiple electrodes: An in vivo comparison study of switching monopolar versus switching bipolar modes in porcine livers - Fig 5
2017Co-Authors: Won Chang, Jeong Min Lee, Jeong Hee Yoon, Dong Ho Lee, Sang Min Lee, Kyoung Bun Lee, Bo Ram Kim, Tae-hyung Kim, Seunghyun Lee, Joon Koo HanAbstract:(a) Photograph shows discolored thickened whitish area of the stomach suggesting thermal injury. (b) (c) Corresponding stomach specimen with hematoxylin and eosin staining (H&E) shows thermal injury to the mucosa. Focal mucosal necrosis is present in (b) (arrow) (x40), and myxoid degeneration of serosa, Subserosa and proper muscle with dilated lymphatic channels, and fluid accumulation in Subserosa are present in (c) (arrow) (x40). (d) Photograph shows the H&E stained stomach specimen without thermal injury (x12.5).
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No-touch radiofrequency ablation using multiple electrodes: An in vivo comparison study of switching monopolar versus switching bipolar modes in porcine livers - Fig 7
2017Co-Authors: Won Chang, Jeong Min Lee, Jeong Hee Yoon, Dong Ho Lee, Sang Min Lee, Kyoung Bun Lee, Bo Ram Kim, Tae-hyung Kim, Seunghyun Lee, Joon Koo HanAbstract:(a) Photograph shows discolored thickened whitish area of the small bowel suggesting thermal injury. (b) (c) Corresponding small bowel specimen with hematoxylin and eosin staining (H&E) shows thermal injury to the mucosa. Mucosal ulceration was noted in (b) (arrow) (x100). Chronic active inflammation in serosa and Subserosa with focal necrosis are present in (c) (arrow) (x100). (d) Photograph shows the H&E stained small bowel specimen without thermal injury (x100).
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No-touch radiofrequency ablation using multiple electrodes: An in vivo comparison study of switching monopolar versus switching bipolar modes in porcine livers - Fig 6
2017Co-Authors: Won Chang, Jeong Min Lee, Jeong Hee Yoon, Dong Ho Lee, Sang Min Lee, Kyoung Bun Lee, Bo Ram Kim, Tae-hyung Kim, Seunghyun Lee, Joon Koo HanAbstract:(a) Photograph shows the whitish area of the gall bladder suggesting thermal injury (arrow). (b) (c) Corresponding gall bladder specimen and adjacent liver parenchyma with hematoxylin and eosin staining (H&E) show thermal injury to the mucosa. Mucosal and submucosal damage are evident. Lymphatic dilatation of Subserosa is noted in (b) (circle) (x12.5). The mucosal epithelium is replaced by dense fibrosis in (c) (arrow) (x100). (d) Photograph shows the H&E stained gall bladder specimen without thermal injury (x100).
Enzan H - One of the best experts on this subject based on the ideXlab platform.
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Cytokeratin-positive Subserosal myofibroblasts in gastroduodenal ulcer; another type of myofibroblasts
2006Co-Authors: Guo L, Kuroda N, Nakayama H, Miyazaki E, Hayashi Y, Toi M, Hiroi M, Enzan HAbstract:To investigate the distribution and origin of alpha-smooth muscle actin (ASMA)-positive stromal cells in the perforation of human gastroduodenal ulcers. Perforative lesions of 24 surgically resected gastroduodenal ulcers were examined immunohistochemically for ASMA, HCD, CD34, CD31, CAM5.2 and HMW-CK, and double staining of ASMA and CAM5.2 was also performed. In addition, to determine the cell source of collagen, in situ hybridization of collagen 1 mRNA was performed. In the normal gastroduodenal wall, the reticular network of CD34-positive stromal cells was identified in the muscularis mucosa, submucosa, muscular propria, and Subserosa. In the subepithelial area, many myofibroblasts were observed, whereas no CD34-positive stromal cells were seen. In areas neighboring ulcerative lesions, no CD34-positive stromal cells were observed, but a significant number of myofibroblasts were present there. In the deep layer of ulceration, numerous fusiform or stellate stromal cells strongly positive for ASMA and CAM5.2 were observed in the Subserosal area around the perforation. In the same site, many cells co-expressing ASMA and CAM5.2 were identified by double staining. In contrast, in the surface layer of ulceration, stromal cells expressing only ASMA were observed. The cytokeratin-positive Subserosal myofibroblastic cell in human gastroduodenal ulcer is a novel type of myofibroblast.Cell BiologyPathologySCI(E)0ARTICLE7697-7042
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α Smooth muscle actin positive stromal cells in gastric carcinoma
2002Co-Authors: Nakayama H, Miyazaki E, Enzan H, Toi MAbstract:Aims: To investigate the distribution and roles of α smooth muscle actin (ASMA) positive stromal cells (ASMA+ cells), which belong to the myofibroblast group, within gastric carcinomas, with reference to three histological types (diffuse type, intestinal type, and solid type). Methods: In total, 74 surgically resected gastric carcinomas (24 diffuse type, 43 intestinal type, and seven solid type) were examined. ASMA positive and high molecular weight caldesmon (HCD) negative stromal cells were regarded as ASMA+ cells. The distribution of CD34 positive stromal cells (CD34+ cells) was also analysed immunohistochemically. Results: In the 24 diffuse-type gastric carcinomas, six of the 13 carcinomas invading the Subserosa had ASMA+ cells in the tumour stroma, whereas all six diffuse-type gastric carcinomas confined to the submucosa and all five invading the muscularis propria had no ASMA+ cells in the tumour stroma. In the 43 intestinal-type gastric carcinomas, only five of the 21 carcinomas confined to the submucosa had ASMA+ cells in the tumour stroma, whereas 21 of the 22 intestinal-type gastric carcinomas invading the muscularis propria and the Subserosa had ASMA+ cell bundles in the tumour stroma. The distribution of CD34+ cells in diffuse-type and intestinal-type gastric carcinomas was similar to that seen in a previously published series. All seven solid-type gastric carcinomas examined had ASMA+ cells but not CD34+ cells in the tumour stroma. No stromal cells double positive for ASMA and CD34 were detected within the diffuse-type tumours examined. Conclusions: These results suggest that ASMA expression in stromal cells is associated with tumour stroma formation of diffuse-type gastric carcinomas invading the Subserosa, intestinal-type gastric carcinomas invading the muscularis propria and Subserosa, and solid-type gastric carcinomas
Jie Zhang - One of the best experts on this subject based on the ideXlab platform.
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pneumatosis cystoides intestinalis six case reports and a review of the literature
2018Co-Authors: Yong Juan Wang, Yu Ming Wang, Yan Min Zheng, Hui Qing Jiang, Jie ZhangAbstract:Background Pneumatosis cystoides intestinalis (PCI) is characterized by gas-filled cysts in the intestinal submucosa and Subserosa. There are few reports of PCI occurring in duodenum and rectum. Here we demonstrated four different endoscopic manifestations of PCI and three cases with intestinal stricture all were successfully managed by medical conservative treatment.
Toi M - One of the best experts on this subject based on the ideXlab platform.
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Cytokeratin-positive Subserosal myofibroblasts in gastroduodenal ulcer; another type of myofibroblasts
2006Co-Authors: Guo L, Kuroda N, Nakayama H, Miyazaki E, Hayashi Y, Toi M, Hiroi M, Enzan HAbstract:To investigate the distribution and origin of alpha-smooth muscle actin (ASMA)-positive stromal cells in the perforation of human gastroduodenal ulcers. Perforative lesions of 24 surgically resected gastroduodenal ulcers were examined immunohistochemically for ASMA, HCD, CD34, CD31, CAM5.2 and HMW-CK, and double staining of ASMA and CAM5.2 was also performed. In addition, to determine the cell source of collagen, in situ hybridization of collagen 1 mRNA was performed. In the normal gastroduodenal wall, the reticular network of CD34-positive stromal cells was identified in the muscularis mucosa, submucosa, muscular propria, and Subserosa. In the subepithelial area, many myofibroblasts were observed, whereas no CD34-positive stromal cells were seen. In areas neighboring ulcerative lesions, no CD34-positive stromal cells were observed, but a significant number of myofibroblasts were present there. In the deep layer of ulceration, numerous fusiform or stellate stromal cells strongly positive for ASMA and CAM5.2 were observed in the Subserosal area around the perforation. In the same site, many cells co-expressing ASMA and CAM5.2 were identified by double staining. In contrast, in the surface layer of ulceration, stromal cells expressing only ASMA were observed. The cytokeratin-positive Subserosal myofibroblastic cell in human gastroduodenal ulcer is a novel type of myofibroblast.Cell BiologyPathologySCI(E)0ARTICLE7697-7042
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α Smooth muscle actin positive stromal cells in gastric carcinoma
2002Co-Authors: Nakayama H, Miyazaki E, Enzan H, Toi MAbstract:Aims: To investigate the distribution and roles of α smooth muscle actin (ASMA) positive stromal cells (ASMA+ cells), which belong to the myofibroblast group, within gastric carcinomas, with reference to three histological types (diffuse type, intestinal type, and solid type). Methods: In total, 74 surgically resected gastric carcinomas (24 diffuse type, 43 intestinal type, and seven solid type) were examined. ASMA positive and high molecular weight caldesmon (HCD) negative stromal cells were regarded as ASMA+ cells. The distribution of CD34 positive stromal cells (CD34+ cells) was also analysed immunohistochemically. Results: In the 24 diffuse-type gastric carcinomas, six of the 13 carcinomas invading the Subserosa had ASMA+ cells in the tumour stroma, whereas all six diffuse-type gastric carcinomas confined to the submucosa and all five invading the muscularis propria had no ASMA+ cells in the tumour stroma. In the 43 intestinal-type gastric carcinomas, only five of the 21 carcinomas confined to the submucosa had ASMA+ cells in the tumour stroma, whereas 21 of the 22 intestinal-type gastric carcinomas invading the muscularis propria and the Subserosa had ASMA+ cell bundles in the tumour stroma. The distribution of CD34+ cells in diffuse-type and intestinal-type gastric carcinomas was similar to that seen in a previously published series. All seven solid-type gastric carcinomas examined had ASMA+ cells but not CD34+ cells in the tumour stroma. No stromal cells double positive for ASMA and CD34 were detected within the diffuse-type tumours examined. Conclusions: These results suggest that ASMA expression in stromal cells is associated with tumour stroma formation of diffuse-type gastric carcinomas invading the Subserosa, intestinal-type gastric carcinomas invading the muscularis propria and Subserosa, and solid-type gastric carcinomas
