The Experts below are selected from a list of 72252 Experts worldwide ranked by ideXlab platform
Konrad Hungerbuhler - One of the best experts on this subject based on the ideXlab platform.
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fluorinated alternatives to long chain perfluoroalkyl carboxylic Acids pfcas perfluoroalkane Sulfonic Acids pfsas and their potential precursors
Environment International, 2013Co-Authors: Zhanyun Wang, Ian T. Cousins, Martin Scheringer, Konrad HungerbuhlerAbstract:Since 2000 there has been an on-going industrial transition to replace long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their precursors. To date, information on these replacements including their chemical identities, however, has not been published or made easily accessible to the public, hampering risk assessment and management of these chemicals. Here we review information on fluorinated alternatives in the public domain. We identify over 20 fluorinated substances that are applied in [i] fluoropolymer manufacture, [ii] surface treatment of textile, leather and carpets, [iii] surface treatment of food contact materials, [iv] metal plating, [v] fire-fighting foams, and [vi] other commercial and consumer products. We summarize current knowledge on their environmental releases, persistence, and exposure of biota and humans. Based on the limited information available, it is unclear whether fluorinated alternatives are safe for humans and the environment. We identify three major data gaps that must be filled to perform meaningful risk assessments and recommend generation of the missing data through cooperation among all stakeholders (industry, regulators, academic scientists and the public).
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Fluorinated alternatives to long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their potential precursors
Environment International, 2013Co-Authors: Zhanyun Wang, Ian T. Cousins, Martin Scheringer, Konrad HungerbuhlerAbstract:Since 2000 there has been an on-going industrial transition to replace long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their precursors. To date, information on these replacements including their chemical identities, however, has not been published or made easily accessible to the public, hampering risk assessment and management of these chemicals. Here we review information on fluorinated alternatives in the public domain. We identify over 20 fluorinated substances that are applied in [i] fluoropolymer manufacture, [ii] surface treatment of textile, leather and carpets, [iii] surface treatment of food contact materials, [iv] metal plating, [v] fire-fighting foams, and [vi] other commercial and consumer products. We summarize current knowledge on their environmental releases, persistence, and exposure of biota and humans. Based on the limited information available, it is unclear whether fluorinated alternatives are safe for humans and the environment. We identify three major data gaps that must be filled to perform meaningful risk assessments and recommend generation of the missing data through cooperation among all stakeholders (industry, regulators, academic scientists and the public). © 2013 Elsevier Ltd.
Xiaoming Zhao - One of the best experts on this subject based on the ideXlab platform.
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synthesis of allylic Sulfonic Acids via regioselective pd catalyzed allylic substitutions of na2so3
Tetrahedron Letters, 2015Co-Authors: Xiaoming ZhaoAbstract:Abstract Palladium-catalyzed allylic sulfonations of the linear allylic carbonates with sodium sulfite (Na 2 SO 3 ) were accomplished under mild conditions. This method gave allylic Sulfonic Acids in good to excellent yields with high level of regioselectivities.
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enantioselective transformation of na2so3 into allylic Sulfonic Acids under pd catalysis
Chemical Communications, 2015Co-Authors: Xiaoming Zhao, Hongbo Zhang, Liang ZhangAbstract:Pd-catalyzed asymmetric allylic sulfonation of di-aryl-substituted allylic acetates with sodium sulfite (Na2SO3) in THF–H2O at room temperature was described. This method directly provided allylic Sulfonic Acids in up to excellent yield and enantioselectivity.
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asymmetric synthesis of allylic Sulfonic Acids enantio and regioselective iridium catalyzed allylations of na2so3
Chemistry: A European Journal, 2014Co-Authors: Xiaoming Zhao, Hongbo Zhang, Liang Zhang, Mingzhu ZhaoAbstract:An enantioselective allylation reaction of allylic carbonates with sodium sulfite (Na2SO3) catalyzed by Ir complex was accomplished, providing allylic Sulfonic Acids in good to excellent yields with a high level of enantio- and regioselectivities. (R)-2-Phenyl-2-sulfoacetic acid, a key intermediate for the synthesis of Cefsulodin and Sulbenicillin, was synthesized as well.
Zhanyun Wang - One of the best experts on this subject based on the ideXlab platform.
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fluorinated alternatives to long chain perfluoroalkyl carboxylic Acids pfcas perfluoroalkane Sulfonic Acids pfsas and their potential precursors
Environment International, 2013Co-Authors: Zhanyun Wang, Ian T. Cousins, Martin Scheringer, Konrad HungerbuhlerAbstract:Since 2000 there has been an on-going industrial transition to replace long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their precursors. To date, information on these replacements including their chemical identities, however, has not been published or made easily accessible to the public, hampering risk assessment and management of these chemicals. Here we review information on fluorinated alternatives in the public domain. We identify over 20 fluorinated substances that are applied in [i] fluoropolymer manufacture, [ii] surface treatment of textile, leather and carpets, [iii] surface treatment of food contact materials, [iv] metal plating, [v] fire-fighting foams, and [vi] other commercial and consumer products. We summarize current knowledge on their environmental releases, persistence, and exposure of biota and humans. Based on the limited information available, it is unclear whether fluorinated alternatives are safe for humans and the environment. We identify three major data gaps that must be filled to perform meaningful risk assessments and recommend generation of the missing data through cooperation among all stakeholders (industry, regulators, academic scientists and the public).
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Fluorinated alternatives to long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their potential precursors
Environment International, 2013Co-Authors: Zhanyun Wang, Ian T. Cousins, Martin Scheringer, Konrad HungerbuhlerAbstract:Since 2000 there has been an on-going industrial transition to replace long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their precursors. To date, information on these replacements including their chemical identities, however, has not been published or made easily accessible to the public, hampering risk assessment and management of these chemicals. Here we review information on fluorinated alternatives in the public domain. We identify over 20 fluorinated substances that are applied in [i] fluoropolymer manufacture, [ii] surface treatment of textile, leather and carpets, [iii] surface treatment of food contact materials, [iv] metal plating, [v] fire-fighting foams, and [vi] other commercial and consumer products. We summarize current knowledge on their environmental releases, persistence, and exposure of biota and humans. Based on the limited information available, it is unclear whether fluorinated alternatives are safe for humans and the environment. We identify three major data gaps that must be filled to perform meaningful risk assessments and recommend generation of the missing data through cooperation among all stakeholders (industry, regulators, academic scientists and the public). © 2013 Elsevier Ltd.
Sheryl A Tittlemier - One of the best experts on this subject based on the ideXlab platform.
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determination of polyfluoroalkyl phosphoric acid diesters perfluoroalkyl phosphonic Acids perfluoroalkyl phosphinic Acids perfluoroalkyl carboxylic Acids and perfluoroalkane Sulfonic Acids in lake trout from the great lakes region
Analytical and Bioanalytical Chemistry, 2012Co-Authors: Eric J Reiner, Satyendra P Bhavsar, Paul A Helm, Scott A Mabury, Eric Braekevelt, Sheryl A TittlemierAbstract:A comprehensive method to extract perfluoroalkyl carboxylic Acids, perfluoroalkane Sulfonic Acids, perfluoroalkyl phosphonic Acids, perfluoroalkyl phosphinic Acids, and polyfluoroalkyl phosphoric acid diesters simultaneously from fish samples has been developed. The recoveries of target compounds ranged from 78 % to 121 %. The new method was used to analyze lake trout (Salvelinus namaycush) from the Great Lakes region. The results showed that the total perfluoroalkane sulfonate concentrations ranged from 0.1 to 145 ng/g (wet weight) with perfluorooctane sulfonate (PFOS) as the dominant contaminant. Concentrations in fish between lakes were in the order of Lakes Ontario ≈ Erie > Huron > Superior ≈ Nipigon. The total perfluoroalkyl carboxylic acid concentrations ranged from 0.2 to 18.2 ng/g wet weight. The aggregate mean perfluorooctanoic acid (PFOA) concentration in fish across all lakes was 0.045 ± 0.023 ng/g. Mean concentrations of PFOA were not significantly different (p > 0.1) among the five lakes. Perfluoroalkyl phosphinic Acids were detected in lake trout from Lake Ontario, Lake Erie, and Lake Huron with concentration ranging from non-detect (ND) to 0.032 ng/g. Polyfluoroalkyl phosphoric acid diesters were detected only in lake trout from Lake Huron, at levels similar to perfluorooctanoic acid.
Ian T. Cousins - One of the best experts on this subject based on the ideXlab platform.
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fluorinated alternatives to long chain perfluoroalkyl carboxylic Acids pfcas perfluoroalkane Sulfonic Acids pfsas and their potential precursors
Environment International, 2013Co-Authors: Zhanyun Wang, Ian T. Cousins, Martin Scheringer, Konrad HungerbuhlerAbstract:Since 2000 there has been an on-going industrial transition to replace long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their precursors. To date, information on these replacements including their chemical identities, however, has not been published or made easily accessible to the public, hampering risk assessment and management of these chemicals. Here we review information on fluorinated alternatives in the public domain. We identify over 20 fluorinated substances that are applied in [i] fluoropolymer manufacture, [ii] surface treatment of textile, leather and carpets, [iii] surface treatment of food contact materials, [iv] metal plating, [v] fire-fighting foams, and [vi] other commercial and consumer products. We summarize current knowledge on their environmental releases, persistence, and exposure of biota and humans. Based on the limited information available, it is unclear whether fluorinated alternatives are safe for humans and the environment. We identify three major data gaps that must be filled to perform meaningful risk assessments and recommend generation of the missing data through cooperation among all stakeholders (industry, regulators, academic scientists and the public).
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Fluorinated alternatives to long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their potential precursors
Environment International, 2013Co-Authors: Zhanyun Wang, Ian T. Cousins, Martin Scheringer, Konrad HungerbuhlerAbstract:Since 2000 there has been an on-going industrial transition to replace long-chain perfluoroalkyl carboxylic Acids (PFCAs), perfluoroalkane Sulfonic Acids (PFSAs) and their precursors. To date, information on these replacements including their chemical identities, however, has not been published or made easily accessible to the public, hampering risk assessment and management of these chemicals. Here we review information on fluorinated alternatives in the public domain. We identify over 20 fluorinated substances that are applied in [i] fluoropolymer manufacture, [ii] surface treatment of textile, leather and carpets, [iii] surface treatment of food contact materials, [iv] metal plating, [v] fire-fighting foams, and [vi] other commercial and consumer products. We summarize current knowledge on their environmental releases, persistence, and exposure of biota and humans. Based on the limited information available, it is unclear whether fluorinated alternatives are safe for humans and the environment. We identify three major data gaps that must be filled to perform meaningful risk assessments and recommend generation of the missing data through cooperation among all stakeholders (industry, regulators, academic scientists and the public). © 2013 Elsevier Ltd.
