The Experts below are selected from a list of 114 Experts worldwide ranked by ideXlab platform
Mitsuo Kodomari - One of the best experts on this subject based on the ideXlab platform.
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one pot synthesis using the Supported Reagent system na2co3 sio2 ppa sio2 synthesis of benzo b thiophenes and naphthothiophenes
Synthesis, 2008Co-Authors: Tadashi Aoyama, Toshio Takido, Mami Orito, Mitsuo KodomariAbstract:A simple and efficient method has been developed for the synthesis of benzo[ B]thiophenes and naphtho[2,1- B]thiophenes from arenethiols and α-halo ketones using Na 2 CO 3 /SiO 2 -PPA/SiO 2 . Reaction of α-halo ketones with arenethiols is promoted by Na 2 CO 3 /SiO 2 to afford α-sulfanyl ketones, which cyclize in the presence of PPA/SiO 2 to give the corresponding thiophene-fused arenes in one-pot. The reaction using α-bromo acetals instead of α-halo ketones also gave the corresponding naphtho[2,1- B]thiophenes via a three-step reaction in one-pot.
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stereoselective synthesis of 2 4 disubstituted thiochromans using the Supported Reagent system na2co3 sio2 ppa sio2
Synlett, 2007Co-Authors: Tadashi Aoyama, Kazuyuki Okada, Hideaki Nakajima, Takuo Matsumoto, Toshio Takido, Mitsuo KodomariAbstract:A simple and efficient method has been developed for the stereoselective synthesis of 2,4-disubstituted thiochromans from arylthiols and α,β-unsaturated aldehydes by using an acid- and a base-Supported Reagent system, Na 2 CO 3 /SiO 2 -PPA/SiO 2 . Michael addition of arylthiol to α,β-unsaturated aldehydes was promoted by Na 2 CΟ 3 /SiΟ 2 , and then the product was cyclized in the presence of PPA/SiO 2 .
Tadashi Aoyama - One of the best experts on this subject based on the ideXlab platform.
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one pot synthesis using the Supported Reagent system na2co3 sio2 ppa sio2 synthesis of benzo b thiophenes and naphthothiophenes
Synthesis, 2008Co-Authors: Tadashi Aoyama, Toshio Takido, Mami Orito, Mitsuo KodomariAbstract:A simple and efficient method has been developed for the synthesis of benzo[ B]thiophenes and naphtho[2,1- B]thiophenes from arenethiols and α-halo ketones using Na 2 CO 3 /SiO 2 -PPA/SiO 2 . Reaction of α-halo ketones with arenethiols is promoted by Na 2 CO 3 /SiO 2 to afford α-sulfanyl ketones, which cyclize in the presence of PPA/SiO 2 to give the corresponding thiophene-fused arenes in one-pot. The reaction using α-bromo acetals instead of α-halo ketones also gave the corresponding naphtho[2,1- B]thiophenes via a three-step reaction in one-pot.
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stereoselective synthesis of 2 4 disubstituted thiochromans using the Supported Reagent system na2co3 sio2 ppa sio2
Synlett, 2007Co-Authors: Tadashi Aoyama, Kazuyuki Okada, Hideaki Nakajima, Takuo Matsumoto, Toshio Takido, Mitsuo KodomariAbstract:A simple and efficient method has been developed for the stereoselective synthesis of 2,4-disubstituted thiochromans from arylthiols and α,β-unsaturated aldehydes by using an acid- and a base-Supported Reagent system, Na 2 CO 3 /SiO 2 -PPA/SiO 2 . Michael addition of arylthiol to α,β-unsaturated aldehydes was promoted by Na 2 CΟ 3 /SiΟ 2 , and then the product was cyclized in the presence of PPA/SiO 2 .
Dilip Konwar - One of the best experts on this subject based on the ideXlab platform.
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kf al2o3 solid Supported Reagent used in 1 3 dipolar cycloaddition reaction of nitrile oxide
ChemInform, 2013Co-Authors: Monalisa Boruah, Dilip KonwarAbstract:An efficient one-pot synthesis of 2-isoxazolines via cycloaddition of nitrile oxides with olefins using solid-Supported KF as base is presented.
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kf al2o3 solid Supported Reagent used in 1 3 dipolar cycloaddition reaction of nitrile oxide
Synthetic Communications, 2012Co-Authors: Monalisa Boruah, Dilip KonwarAbstract:Abstract The stereoselective synthesis of 2-isoxazolidine through 1,3-dipolar cycloaddition reaction of nitrile oxide, which is in situ generation from aldoxime in the presence of N-bromosuccinamide and solid-Supported Reagent KF/Al2O3 at room temperature, is reported. KF/Al2O3 is sufficiently basic such that it can replace organic bases such as Et3N used in typical procedures and it catalyses the reaction to enhance the rate of the reaction.
Gilles Subra - One of the best experts on this subject based on the ideXlab platform.
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Oxyfold: a simple and efficient solid-Supported Reagent for disulfide bond formation.
Chemistry an Asian journal, 2011Co-Authors: Pascal Verdié, Luisa Ronga, Michèle Cristau, Muriel Amblard, Sonia Cantel, Christine Enjalbal, Karine Puget, Jean Martinez, Gilles SubraAbstract:The synthesis and use of novel polymer-Supported Reagents for disulfide bond formation is described. This family of Supported Reagents consists of a series of oxidized methionines grafted onto a solid support. Their cost and the simplicity of their preparation through N-carboxyanhydride polymerization on beads make them reactants of choice for the formation of disulfide bridges in peptides.
Toshio Takido - One of the best experts on this subject based on the ideXlab platform.
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one pot synthesis using the Supported Reagent system na2co3 sio2 ppa sio2 synthesis of benzo b thiophenes and naphthothiophenes
Synthesis, 2008Co-Authors: Tadashi Aoyama, Toshio Takido, Mami Orito, Mitsuo KodomariAbstract:A simple and efficient method has been developed for the synthesis of benzo[ B]thiophenes and naphtho[2,1- B]thiophenes from arenethiols and α-halo ketones using Na 2 CO 3 /SiO 2 -PPA/SiO 2 . Reaction of α-halo ketones with arenethiols is promoted by Na 2 CO 3 /SiO 2 to afford α-sulfanyl ketones, which cyclize in the presence of PPA/SiO 2 to give the corresponding thiophene-fused arenes in one-pot. The reaction using α-bromo acetals instead of α-halo ketones also gave the corresponding naphtho[2,1- B]thiophenes via a three-step reaction in one-pot.
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stereoselective synthesis of 2 4 disubstituted thiochromans using the Supported Reagent system na2co3 sio2 ppa sio2
Synlett, 2007Co-Authors: Tadashi Aoyama, Kazuyuki Okada, Hideaki Nakajima, Takuo Matsumoto, Toshio Takido, Mitsuo KodomariAbstract:A simple and efficient method has been developed for the stereoselective synthesis of 2,4-disubstituted thiochromans from arylthiols and α,β-unsaturated aldehydes by using an acid- and a base-Supported Reagent system, Na 2 CO 3 /SiO 2 -PPA/SiO 2 . Michael addition of arylthiol to α,β-unsaturated aldehydes was promoted by Na 2 CΟ 3 /SiΟ 2 , and then the product was cyclized in the presence of PPA/SiO 2 .