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Maheswari Senthil - One of the best experts on this subject based on the ideXlab platform.

  • abstract c85 community based participatory research leads to Sustainable Lifestyle intervention program for reducing breast cancer risk among african american and latina women
    Cancer Epidemiology Biomarkers & Prevention, 2014
    Co-Authors: Padma Tadi P Uppala, Amanda Dupre, Persila Mohammadnia, Loistine Herndon, Hildemar Dos Santos, Maheswari Senthil
    Abstract:

    Minority women are underrepresented in clinical research, which impedes progress in understanding and eliminating health disparities. Reducing health disparities is an important goal of public health community. Recent data suggests that community-based participatory research (CBPR) which systematically involves the affected communities in each stage of the research process-inception, planning, recruitment, conduct and education is the key to reducing health disparities. Between 2001 and 2005 approximately 10,000 invasive and 2,000 in situ breast cancer cases were reported in Region 5 of the San Bernardino County women in California. Although data reveals that the age adjusted incidence rate of 23.7 for in situ breast cancer cases in the Region 5 population is lower than the state-wide rate of 27.3, the number of in situ cases in the area rose from 9.6 in 1988 to 24.8 in 2007. Obesity rates for African American (AA) and Latina adults in the San Bernardino County are 34%. The emergence of the obesity epidemic worldwide has been associated with increases in metabolic syndrome, breast cancer, and type 2 diabetes in the industrialized countries. The proposed pilot study used a CBPR method to study women9s perceptions, beliefs and attitudes towards participating in a clinical breast cancer study that involved blood. Methods: A community-based participatory mixed-methods approach, including a 6-month Lifestyle intervention education program was employed. Participants were recruited using purposive convenience sampling that evaluated educational program designed to increase women9s knowledge of positive attitudes and participation in breast cancer clinical studies and simple changes in Lifestyle that result in reduced risk for breast cancer. To evaluate the effectiveness of the educational intervention, we used knowledge, attitudes, behavior, and perception-based questionnaire, and in-depth interviews to assess changes before and after the educational experience. Results: Fifty eight women that included 36 African American and 22 Latina women participated in the educational program, out of which twenty five women were recruited into the Lifestyle intervention program that required providing blood to test for metabolic syndrome and risk for breast cancer. All the women in the intervention study were willing to provide blood for the study. Seventy six percent of the women in the Lifestyle intervention program were either obese or experienced metabolic syndrome. At the end of six months, 78% of the women who participated in the study reduced their body fat by 2% change, by reducing dietary fat consumption. Approximately 93% of the women increased servings of fruits and vegetables in their diet and engaged in some form of exercise after their enrollment into the study. This program is currently sustained by community support groups, after the end of the grant. The project director meets with the women once a month and monitors their life style changes. Conclusion: Community-based participatory research projects that engage community partners through the entire process of research planning and conduct may result in effective Sustainable projects that will result in resilient communities. Funding supported by Kaiser Permanente Fontana Community Benefit Grant. Citation Format: Padma Pauline Tadi Uppala, Padma Pauline Tadi Uppala, Loistine Herndon, Hildemar Dos Santos, Amanda Dupre, Persila Mohammadnia, Maheswari Senthil. Community-based participatory research leads to Sustainable Lifestyle intervention program for reducing breast cancer risk among African American and Latina women. [abstract]. In: Proceedings of the Sixth AACR Conference: The Science of Cancer Health Disparities; Dec 6–9, 2013; Atlanta, GA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2014;23(11 Suppl):Abstract nr C85. doi:10.1158/1538-7755.DISP13-C85

  • abstract 2442 community based participatory research leads to Sustainable Lifestyle intervention program for reducing breast cancer risk among african american and latina women
    Cancer Research, 2014
    Co-Authors: Padma Tadi P Uppala, Hildemaar Dos Santos, Amanda Dupre, Persila Mohammadnia, Maheswari Senthil
    Abstract:

    Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Breast cancer mortality rates are higher among African American (AA) women in San Bernardino County (SBC) at 36.31 per 100,000 women compared with white women in the same region, as well as with California breast cancer rates and the national averages. In addition, approximately 30% of individuals in SBC are obese. Mortality rates for diabetes in SBC between 2009 -2011 were 33 per 100,000 adults. Recent literature suggests an association between obesity, diabetes, metabolic syndrome and triple-negative breast cancer (TNBC). The insulin-leptin adiponectin axis has been implicated in these breast tumors that are insensitive to estrogen. TNBC is common among premenopausal AA and Latina women and is unclear whether overweight women or those with metabolic syndrome are at increased risk for breast cancer. Engaging minority AA and Latina women in clinical research has been difficult. Mistrust of doctors and scientists is reported as a barrier to participation. In this pilot study, community-based participatory (CBPR) methods were used to study women's perceptions, beliefs and attitudes towards participating in a breast cancer clinical study. Methods: A CBPR mixed-methods approach, including a 6-month Lifestyle intervention education program was employed. Participants were recruited using purposive convenience sampling. To evaluate the effectiveness of the Lifestyle intervention educational program, we used knowledge, attitudes, behavior, and perception-based questionnaire to assess changes before and after the educational experience. Results: Fifty eight women that included 36 African American and 22 Latina women participated in the educational program, out of which twenty five women were recruited into the Lifestyle intervention program that required providing blood to test for metabolic syndrome and risk for breast cancer. All the women in the intervention study were willing to provide blood for the study. Seventy six percent of the women in the Lifestyle intervention program were either obese or experienced metabolic syndrome. At the end of six months, 78% of the women who participated in the study reduced their body fat by 2% change, by reducing dietary fat consumption. Approximately 93% of the women increased servings of fruits and vegetables in their diet and engaged in some form of exercise after their enrollment into the study. This program is currently sustained by community support groups, after the end of the grant. Conclusion: Community-based participatory research projects that engage community partners through the entire process of research planning and conduct may result in effective Sustainable projects that will result in resilient communities. Funding supported by Kaiser Permanente Fontana Community Benefit Grant. Citation Format: Padma P. Tadi Uppala, Hildemaar Dos Santos, Amanda Dupre, Persila Mohammadnia, Maheswari Senthil. Community-based participatory research leads to Sustainable Lifestyle intervention program for reducing breast cancer risk among African American and Latina women. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 2442. doi:10.1158/1538-7445.AM2014-2442

David R Lubans - One of the best experts on this subject based on the ideXlab platform.

Padma Tadi P Uppala - One of the best experts on this subject based on the ideXlab platform.

  • abstract c85 community based participatory research leads to Sustainable Lifestyle intervention program for reducing breast cancer risk among african american and latina women
    Cancer Epidemiology Biomarkers & Prevention, 2014
    Co-Authors: Padma Tadi P Uppala, Amanda Dupre, Persila Mohammadnia, Loistine Herndon, Hildemar Dos Santos, Maheswari Senthil
    Abstract:

    Minority women are underrepresented in clinical research, which impedes progress in understanding and eliminating health disparities. Reducing health disparities is an important goal of public health community. Recent data suggests that community-based participatory research (CBPR) which systematically involves the affected communities in each stage of the research process-inception, planning, recruitment, conduct and education is the key to reducing health disparities. Between 2001 and 2005 approximately 10,000 invasive and 2,000 in situ breast cancer cases were reported in Region 5 of the San Bernardino County women in California. Although data reveals that the age adjusted incidence rate of 23.7 for in situ breast cancer cases in the Region 5 population is lower than the state-wide rate of 27.3, the number of in situ cases in the area rose from 9.6 in 1988 to 24.8 in 2007. Obesity rates for African American (AA) and Latina adults in the San Bernardino County are 34%. The emergence of the obesity epidemic worldwide has been associated with increases in metabolic syndrome, breast cancer, and type 2 diabetes in the industrialized countries. The proposed pilot study used a CBPR method to study women9s perceptions, beliefs and attitudes towards participating in a clinical breast cancer study that involved blood. Methods: A community-based participatory mixed-methods approach, including a 6-month Lifestyle intervention education program was employed. Participants were recruited using purposive convenience sampling that evaluated educational program designed to increase women9s knowledge of positive attitudes and participation in breast cancer clinical studies and simple changes in Lifestyle that result in reduced risk for breast cancer. To evaluate the effectiveness of the educational intervention, we used knowledge, attitudes, behavior, and perception-based questionnaire, and in-depth interviews to assess changes before and after the educational experience. Results: Fifty eight women that included 36 African American and 22 Latina women participated in the educational program, out of which twenty five women were recruited into the Lifestyle intervention program that required providing blood to test for metabolic syndrome and risk for breast cancer. All the women in the intervention study were willing to provide blood for the study. Seventy six percent of the women in the Lifestyle intervention program were either obese or experienced metabolic syndrome. At the end of six months, 78% of the women who participated in the study reduced their body fat by 2% change, by reducing dietary fat consumption. Approximately 93% of the women increased servings of fruits and vegetables in their diet and engaged in some form of exercise after their enrollment into the study. This program is currently sustained by community support groups, after the end of the grant. The project director meets with the women once a month and monitors their life style changes. Conclusion: Community-based participatory research projects that engage community partners through the entire process of research planning and conduct may result in effective Sustainable projects that will result in resilient communities. Funding supported by Kaiser Permanente Fontana Community Benefit Grant. Citation Format: Padma Pauline Tadi Uppala, Padma Pauline Tadi Uppala, Loistine Herndon, Hildemar Dos Santos, Amanda Dupre, Persila Mohammadnia, Maheswari Senthil. Community-based participatory research leads to Sustainable Lifestyle intervention program for reducing breast cancer risk among African American and Latina women. [abstract]. In: Proceedings of the Sixth AACR Conference: The Science of Cancer Health Disparities; Dec 6–9, 2013; Atlanta, GA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2014;23(11 Suppl):Abstract nr C85. doi:10.1158/1538-7755.DISP13-C85

  • abstract 2442 community based participatory research leads to Sustainable Lifestyle intervention program for reducing breast cancer risk among african american and latina women
    Cancer Research, 2014
    Co-Authors: Padma Tadi P Uppala, Hildemaar Dos Santos, Amanda Dupre, Persila Mohammadnia, Maheswari Senthil
    Abstract:

    Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Breast cancer mortality rates are higher among African American (AA) women in San Bernardino County (SBC) at 36.31 per 100,000 women compared with white women in the same region, as well as with California breast cancer rates and the national averages. In addition, approximately 30% of individuals in SBC are obese. Mortality rates for diabetes in SBC between 2009 -2011 were 33 per 100,000 adults. Recent literature suggests an association between obesity, diabetes, metabolic syndrome and triple-negative breast cancer (TNBC). The insulin-leptin adiponectin axis has been implicated in these breast tumors that are insensitive to estrogen. TNBC is common among premenopausal AA and Latina women and is unclear whether overweight women or those with metabolic syndrome are at increased risk for breast cancer. Engaging minority AA and Latina women in clinical research has been difficult. Mistrust of doctors and scientists is reported as a barrier to participation. In this pilot study, community-based participatory (CBPR) methods were used to study women's perceptions, beliefs and attitudes towards participating in a breast cancer clinical study. Methods: A CBPR mixed-methods approach, including a 6-month Lifestyle intervention education program was employed. Participants were recruited using purposive convenience sampling. To evaluate the effectiveness of the Lifestyle intervention educational program, we used knowledge, attitudes, behavior, and perception-based questionnaire to assess changes before and after the educational experience. Results: Fifty eight women that included 36 African American and 22 Latina women participated in the educational program, out of which twenty five women were recruited into the Lifestyle intervention program that required providing blood to test for metabolic syndrome and risk for breast cancer. All the women in the intervention study were willing to provide blood for the study. Seventy six percent of the women in the Lifestyle intervention program were either obese or experienced metabolic syndrome. At the end of six months, 78% of the women who participated in the study reduced their body fat by 2% change, by reducing dietary fat consumption. Approximately 93% of the women increased servings of fruits and vegetables in their diet and engaged in some form of exercise after their enrollment into the study. This program is currently sustained by community support groups, after the end of the grant. Conclusion: Community-based participatory research projects that engage community partners through the entire process of research planning and conduct may result in effective Sustainable projects that will result in resilient communities. Funding supported by Kaiser Permanente Fontana Community Benefit Grant. Citation Format: Padma P. Tadi Uppala, Hildemaar Dos Santos, Amanda Dupre, Persila Mohammadnia, Maheswari Senthil. Community-based participatory research leads to Sustainable Lifestyle intervention program for reducing breast cancer risk among African American and Latina women. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 2442. doi:10.1158/1538-7445.AM2014-2442

Yves Vanden Auweele - One of the best experts on this subject based on the ideXlab platform.

  • explaining the psychological effects of a Sustainable Lifestyle physical activity intervention among rural women
    Mental Health and Physical Activity, 2008
    Co-Authors: Joke Opdenacker, Filip Boen, Ilse De Bourdeaudhuij, Yves Vanden Auweele
    Abstract:

    Abstract Objectives To examine the psychological effects of a minimal-contact physical activity intervention that was integrated in the existing structures of a women's organization and to detect possible mechanisms that might mediate these effects. Methods Members ( n  = 108) of four units of a women's organization participated in a 6-month intervention that included one group meeting, a self-help booklet and five monthly reminder letters. Two other units ( n  = 110) served as control group. Primary outcomes were psychological well-being, physical well-being and trait anxiety, which were assessed by self-report questionnaires before and after the intervention. Results There was a significant time by group interaction for psychological well-being and trait anxiety. The control group reported significantly less psychological well-being at posttest, while there was no change in the intervention group. For trait anxiety, there was a significant decrease in the intervention group and no change in the control group. No significant results were found for physical well-being. The effects of the intervention on psychological well-being and trait anxiety were partly mediated by changes in perceived benefits and barriers of physical activity and by changes in self-efficacy, but not by changes in physical activity. Conclusions The present intervention may have been effective in countering the seasonal decrease in psychological well-being during winter, and in decreasing trait anxiety. These effects were partly mediated by changes in perceived benefits and barriers of physical activity and by changes in self-efficacy. The minimal-contact hours and the use of existing structures are important strengths for later implementation.

Fiona Stacey - One of the best experts on this subject based on the ideXlab platform.