The Experts below are selected from a list of 246 Experts worldwide ranked by ideXlab platform
A. Klohnen - One of the best experts on this subject based on the ideXlab platform.
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difference in incisional complications following exploratory celiotomies using antibacterial coated Suture Material for subcutaneous closure prospective randomised study in 100 horses
Equine Veterinary Journal, 2010Co-Authors: A. S. Bischofberger, T. Brauer, G. Gugelchuk, A. KlohnenAbstract:Reasons for performing study Incisional complications are a major post operative challenge following ventral midline exploratory celiotomy for abdominal pain in horses. They lead to discomfort, prolonged hospitalisation, longer recovery times and increased cost; therefore, investigation of preventative procedures are warranted. Objectives To determine the clinical effect of antibacterial (triclosan) coated 2-0 polyglactin 910 Suture Material on the likelihood of incisional infections when used for closure of subcutaneous tissue following ventral midline celiotomies in horses. Methods One hundred horses undergoing exploratory celiotomy assigned at random to one of 2 groups. In the control group coated 2-0 polyglactin 910 (Vicryl) was used for apposition of the subcutaneous tissue in a simple continuous pattern and, in the study group, antibacterial (triclosan) coated 2-0 polyglactin 910 Suture Material (Vicryl Plus) was used. Post operatively an elastic adhesive abdominal bandage was applied, changed and the incision was inspected by a clinician blinded to the study protocol at 24-36 h and 6-9 days post operatively. Outcomes of interest were evidence of incisional pain, incisional oedema, sheath/udder oedema, incisional drainage, hernia formation and dehiscence. Results Antibacterial-coated Suture Material did not decrease the likelihood of incisional complications in 100 horses. Conclusions A beneficial effect on ventral midline incisions in 100 horses was not evident by using antibacterial-coated Suture Material. Potential relevance Lack of effectiveness of antibacterial-coated Suture Material in equine ventral midline closure after exploratory celiotomy and the observed potential adverse effects suggest that further clinical investigations are needed before using such Material routinely on horses.
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Difference in incisional complications following exploratory celiotomies using antibacterial-coated Suture Material for subcutaneous closure: Prospective randomised study in 100 horses
Equine Veterinary Journal, 2010Co-Authors: A. S. Bischofberger, T. Brauer, G. Gugelchuk, A. KlohnenAbstract:REASONS FOR PERFORMING STUDY: Incisional complications are a major post operative challenge following ventral midline exploratory celiotomy for abdominal pain in horses. They lead to discomfort, prolonged hospitalisation, longer recovery times and increased cost; therefore, investigation of preventative procedures are warranted. OBJECTIVES: To determine the clinical effect of antibacterial (triclosan) coated 2-0 polyglactin 910 Suture Material on the likelihood of incisional infections when used for closure of subcutaneous tissue following ventral midline celiotomies in horses. METHODS: One hundred horses undergoing exploratory celiotomy assigned at random to one of 2 groups. In the control group coated 2-0 polyglactin 910 (Vicryl) was used for apposition of the subcutaneous tissue in a simple continuous pattern and, in the study group, antibacterial (triclosan) coated 2-0 polyglactin 910 Suture Material (Vicryl Plus) was used. Post operatively an elastic adhesive abdominal bandage was applied, changed and the incision was inspected by a clinician blinded to the study protocol at 24-36 h and 6-9 days post operatively. Outcomes of interest were evidence of incisional pain, incisional oedema, sheath/udder oedema, incisional drainage, hernia formation and dehiscence. RESULTS: Antibacterial-coated Suture Material did not decrease the likelihood of incisional complications in 100 horses. CONCLUSIONS: A beneficial effect on ventral midline incisions in 100 horses was not evident by using antibacterial-coated Suture Material. POTENTIAL RELEVANCE: Lack of effectiveness of antibacterial-coated Suture Material in equine ventral midline closure after exploratory celiotomy and the observed potential adverse effects suggest that further clinical investigations are needed before using such Material routinely on horses.
Karsten Schmidt - One of the best experts on this subject based on the ideXlab platform.
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biomechanical evaluation of flexor tendon repair using barbed Suture Material a comparative ex vivo study
Journal of Hand Surgery (European Volume), 2011Co-Authors: Philip H Zeplin, Robert K Zahn, Rainer H Meffert, Karsten SchmidtAbstract:Purpose Barbed Suture Material for tendon repair opens up the possibility of a knotless reconstruction due to an increased Suture–tendon interaction. The aim of this study was to compare the tensile strength of a knotted technique with a monofilament polydioxane Suture to that of a knotless technique with a barbed Suture Material, by using a multistrand, modified Kirchmayr-Kessler tenorrhaphy. Methods Sixty human flexor digitorum tendons were randomized into 4 groups. A modified, knotted, multistrand Kirchmayr-Kessler technique with an absorbable, monofilament polydioxane Suture was compared with a modified, knotless, multistrand Kirchmayr-Kessler technique with an absorbable, unidirectional barbed glycolic-carbonate Suture. Tendons were distracted to failure. Mode of failure and load to failure were recorded. Results The knotless 2-strand Kirchmayr-Kessler barbed Suture shows a significantly lower tensile strength than the knotted 2-strand polydioxane Suture (p Conclusions The 2-strand Kirchmayr-Kessler barbed Suture proved to be insufficient and significantly weaker than the 2-strand polydioxane Suture, and therefore it cannot be recommended. With the knotless 4-strand Kirchmayr-Kessler technique, the barbed Suture Material has the potential to be used in flexor tendon surgery, but it has no advantage over the 4-strand polydioxane Suture.
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biomechanical evaluation of flexor tendon repair using barbed Suture Material a comparative ex vivo study
Journal of Hand Surgery (European Volume), 2011Co-Authors: Philip H Zeplin, Robert K Zahn, Rainer H Meffert, Karsten SchmidtAbstract:PURPOSE: Barbed Suture Material for tendon repair opens up the possibility of a knotless reconstruction due to an increased Suture-tendon interaction. The aim of this study was to compare the tensile strength of a knotted technique with a monofilament polydioxane Suture to that of a knotless technique with a barbed Suture Material, by using a multistrand, modified Kirchmayr-Kessler tenorrhaphy. METHODS: Sixty human flexor digitorum tendons were randomized into 4 groups. A modified, knotted, multistrand Kirchmayr-Kessler technique with an absorbable, monofilament polydioxane Suture was compared with a modified, knotless, multistrand Kirchmayr-Kessler technique with an absorbable, unidirectional barbed glycolic-carbonate Suture. Tendons were distracted to failure. Mode of failure and load to failure were recorded. RESULTS: The knotless 2-strand Kirchmayr-Kessler barbed Suture shows a significantly lower tensile strength than the knotted 2-strand polydioxane Suture (p < .001). The comparison of the maximum tensile strength of the knotless (glycolic-carbonate) technique with that of the knotted (polydioxane) 4-strand technique resulted in no significant difference in either technique utilized (p = .737). The tensile strength of the 4-strand technique was greater than that of the corresponding 2-strand technique (p < .001). CONCLUSIONS: The 2-strand Kirchmayr-Kessler barbed Suture proved to be insufficient and significantly weaker than the 2-strand polydioxane Suture, and therefore it cannot be recommended. With the knotless 4-strand Kirchmayr-Kessler technique, the barbed Suture Material has the potential to be used in flexor tendon surgery, but it has no advantage over the 4-strand polydioxane Suture.
Richard Johanson - One of the best experts on this subject based on the ideXlab platform.
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selected cochrane systematic reviews absorbable synthetic versus catgut Suture Material for perineal repair
Birth-issues in Perinatal Care, 2000Co-Authors: Christine Kettle, Richard JohansonAbstract:A substantive amendment to this systematic review was last made on 19 May 1999. Cochrane reviews are regularly checked and updated if necessary. ABSTRACT Background and objectives: Approximately 70% of women will experience some degree of perineal trauma following vaginal delivery and will require stitches. This may result in perineal pain and superficial dyspareunia. The objective of this review was to assess the effects of absorbable synthetic Suture Material as compared with catgut on the amount of short- and long-term pain experienced by mothers following perineal repair. Search strategy: We searched the Cochrane Pregnancy and Childbirth Group trials register. Selection criteria: Randomised trials comparing absorbable synthetic (polyglycolic acid and polyglactin) with plain or chromic catgut Suture for perineal repair in mothers after vaginal delivery. Data collection and analysis: Trial quality was assessed independently by two reviewers. Data were extracted by one reviewer and checked by the second reviewer. Main results: Eight trials were included. Compared with catgut, the polyglycolic acid and polyglactin groups were associated with less pain in first three days (odds ratio 0.62, 95% confidence interval 0.54–0.71). There was also less need for analgesia (odds ratio 0,63, 95% confidence interval 0.52–0.77) and less Suture dehiscence (odds ratio 0.45, 95% confidence interval 0.29–0.70). There was no significant difference in long-term pain (odds ratio 0.81, 95% confidence interval 0.61–1.08). Removal of Suture Material was significantly more common in the polyglycolic acid and polyglactin groups (odds ratio 2.01, 95% confidence interval 1.56–2.58). There was no difference in the amount of dyspareunia experienced by women. Reviewers' conclusions: Absorbable synthetic Suture Material (in the form of polyglycolic acid and polyglactin Sutures) for perineal repair following childbirth appears to decrease women's experience of short-term pain. The length of time taken for the synthetic Material to be absorbed is of concern. A trial addressing the use of polyglactin has recently been completed and this has been included in this updated review. Citation: Kettle C, Johanson RB. Absorbable synthetic versus catgut Suture Material for perineal repair (Cochrane Review). In: The Cochrane Library, Issue 4, 1999, Oxford: Update Software. ••• The preceding report is an abstract of regularly updated, systematic reviews prepared and maintained by the Cochrane Collaboration. The full texts of the reviews are available in The Cochrane Library (ISSN 1464-780X). Seehttp://www.update-software.com/cochrane.htmor contact Update Software,info@update.co.uk, for information on subscribing to The Cochrane Library in your area. Update Software Ltd, Summertown Pavilion, Middle Way, Oxford OX2 7LG, United Kingdom (Tel.: +44 1865 513902; Fax: +44 1865 516918).
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absorbable synthetic versus catgut Suture Material for perineal repair
Cochrane Database of Systematic Reviews, 1999Co-Authors: Christine Kettle, Richard JohansonAbstract:BACKGROUND:Approximately 70% of women will experience some degree of perineal trauma following vaginal delivery and will require stitches. This may result in perineal pain and superficial dyspareunia. OBJECTIVES:The objective of this review was to assess the effects of absorbable synthetic Suture Material as compared with catgut on the amount of short and long term pain experienced by mothers following perineal repair. SEARCH STRATEGY:We searched the Cochrane Pregnancy and Childbirth Group trials register. SELECTION CRITERIA:Randomised trials comparing absorbable synthetic (polyglycolic acid and polyglactin) with plain or chromic catgut Suture for perineal repair in mothers after vaginal delivery. DATA COLLECTION AND ANALYSIS:Trial quality was assessed independently by two reviewers. Data were extracted by one reviewer and checked by the second reviewer. MAIN RESULTS:Eight trials were included. Compared with catgut, the polyglycolic acid and polyglactin groups were associated with less pain in first three days (odds ratio 0.62, 95% confidence interval 0.54 to 0.71). There was also less need for analgesia (odds ratio 0.63, 95% confidence interval 0.52 to 0.77) and less Suture dehiscence (odds ratio 0.45, 95% confidence interval 0.29 to 0.70). There was no significant difference in long term pain (odds ratio 0.81, 95% confidence interval 0.61 to 1.08). Removal of Suture Material was significantly more common in the polyglycolic acid and polyglactin groups (odds ratio 2.01, 95% confidence interval 1.56 to 2.58). There was no difference in the amount of dyspareunia experienced by women. REVIEWER'S CONCLUSIONS:Absorbable synthetic Suture Material (in the form of polyglycolic acid and polyglactin Sutures) for perineal repair following childbirth appears to decrease women's experience of short-term pain. The length of time taken for the synthetic Material to be absorbed is of concern. A trial addressing the use of polyglactin has recently been completed and this has been included in this updated review.
A. S. Bischofberger - One of the best experts on this subject based on the ideXlab platform.
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difference in incisional complications following exploratory celiotomies using antibacterial coated Suture Material for subcutaneous closure prospective randomised study in 100 horses
Equine Veterinary Journal, 2010Co-Authors: A. S. Bischofberger, T. Brauer, G. Gugelchuk, A. KlohnenAbstract:Reasons for performing study Incisional complications are a major post operative challenge following ventral midline exploratory celiotomy for abdominal pain in horses. They lead to discomfort, prolonged hospitalisation, longer recovery times and increased cost; therefore, investigation of preventative procedures are warranted. Objectives To determine the clinical effect of antibacterial (triclosan) coated 2-0 polyglactin 910 Suture Material on the likelihood of incisional infections when used for closure of subcutaneous tissue following ventral midline celiotomies in horses. Methods One hundred horses undergoing exploratory celiotomy assigned at random to one of 2 groups. In the control group coated 2-0 polyglactin 910 (Vicryl) was used for apposition of the subcutaneous tissue in a simple continuous pattern and, in the study group, antibacterial (triclosan) coated 2-0 polyglactin 910 Suture Material (Vicryl Plus) was used. Post operatively an elastic adhesive abdominal bandage was applied, changed and the incision was inspected by a clinician blinded to the study protocol at 24-36 h and 6-9 days post operatively. Outcomes of interest were evidence of incisional pain, incisional oedema, sheath/udder oedema, incisional drainage, hernia formation and dehiscence. Results Antibacterial-coated Suture Material did not decrease the likelihood of incisional complications in 100 horses. Conclusions A beneficial effect on ventral midline incisions in 100 horses was not evident by using antibacterial-coated Suture Material. Potential relevance Lack of effectiveness of antibacterial-coated Suture Material in equine ventral midline closure after exploratory celiotomy and the observed potential adverse effects suggest that further clinical investigations are needed before using such Material routinely on horses.
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Difference in incisional complications following exploratory celiotomies using antibacterial-coated Suture Material for subcutaneous closure: Prospective randomised study in 100 horses
Equine Veterinary Journal, 2010Co-Authors: A. S. Bischofberger, T. Brauer, G. Gugelchuk, A. KlohnenAbstract:REASONS FOR PERFORMING STUDY: Incisional complications are a major post operative challenge following ventral midline exploratory celiotomy for abdominal pain in horses. They lead to discomfort, prolonged hospitalisation, longer recovery times and increased cost; therefore, investigation of preventative procedures are warranted. OBJECTIVES: To determine the clinical effect of antibacterial (triclosan) coated 2-0 polyglactin 910 Suture Material on the likelihood of incisional infections when used for closure of subcutaneous tissue following ventral midline celiotomies in horses. METHODS: One hundred horses undergoing exploratory celiotomy assigned at random to one of 2 groups. In the control group coated 2-0 polyglactin 910 (Vicryl) was used for apposition of the subcutaneous tissue in a simple continuous pattern and, in the study group, antibacterial (triclosan) coated 2-0 polyglactin 910 Suture Material (Vicryl Plus) was used. Post operatively an elastic adhesive abdominal bandage was applied, changed and the incision was inspected by a clinician blinded to the study protocol at 24-36 h and 6-9 days post operatively. Outcomes of interest were evidence of incisional pain, incisional oedema, sheath/udder oedema, incisional drainage, hernia formation and dehiscence. RESULTS: Antibacterial-coated Suture Material did not decrease the likelihood of incisional complications in 100 horses. CONCLUSIONS: A beneficial effect on ventral midline incisions in 100 horses was not evident by using antibacterial-coated Suture Material. POTENTIAL RELEVANCE: Lack of effectiveness of antibacterial-coated Suture Material in equine ventral midline closure after exploratory celiotomy and the observed potential adverse effects suggest that further clinical investigations are needed before using such Material routinely on horses.
J Ryhanen - One of the best experts on this subject based on the ideXlab platform.
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nickel titanium wire as a flexor tendon Suture Material an ex vivo study
Journal of Hand Surgery (European Volume), 2010Co-Authors: T Karjalainen, H Goransson, Anna Viinikainen, T Jamsa, J RyhanenAbstract:Nickel–titanium shape memory alloy (NiTi) is a new Suture Material that is easy to handle, is strong, and biocompatible. The purpose of this study was to evaluate the Material properties and biomechanical behaviour of 150 µm and 200 µm NiTi wires in flexor tendon repair. Braided polyester (4-0 Ethibond®) was used as control. Fifty fresh-frozen porcine flexor tendons were repaired using the Pennington modification of the Kessler repair or a double Kessler technique. NiTi wires were stiffer and reached higher tensile strength compared to braided polyester Suture. Repairs with 200 µm NiTi wire had a higher yield force, ultimate force and better resistance to gapping than 4-0 braided polyester repairs. Repairs made with 200 µm NiTi wire achieved higher stiffness and ultimate force than repairs made with 150 µm NiTi wire.
