The Experts below are selected from a list of 106377 Experts worldwide ranked by ideXlab platform
Piero Salvadori - One of the best experts on this subject based on the ideXlab platform.
-
determination of absolute configuration of acyclic 1 2 diols with mo2 oac 4 1 snatzke s method revisited
Journal of Organic Chemistry, 2001Co-Authors: Di Bari L, Gennaro Pescitelli, C Pratelli, D Pini, Piero SalvadoriAbstract:The method employing dimolydbenum tetraacetate for the assignment of the absolute configuration of optically active 1,2-diols is thoroughly revisited and applied to several compounds, some of which were synthesized by asymmetric cis-dihydroxylation. No exceptions were found to the empirical rule relating the sign of the induced CD spectrum and the configuration of the substrate, whatever its structure and sterical requirements. To broaden the scope of the method, its applicability to critical situations commonly encountered with Synthetic Products is tested. It is demonstrated that the method can be applied on samples with low chemical and optical purity, and that it may lend itself as a means to estimate the ee. The roles of the water content of the sample and of the diol-to-dimolybdenum ratio are investigated.
Di Bari L - One of the best experts on this subject based on the ideXlab platform.
-
determination of absolute configuration of acyclic 1 2 diols with mo2 oac 4 1 snatzke s method revisited
Journal of Organic Chemistry, 2001Co-Authors: Di Bari L, Gennaro Pescitelli, C Pratelli, D Pini, Piero SalvadoriAbstract:The method employing dimolydbenum tetraacetate for the assignment of the absolute configuration of optically active 1,2-diols is thoroughly revisited and applied to several compounds, some of which were synthesized by asymmetric cis-dihydroxylation. No exceptions were found to the empirical rule relating the sign of the induced CD spectrum and the configuration of the substrate, whatever its structure and sterical requirements. To broaden the scope of the method, its applicability to critical situations commonly encountered with Synthetic Products is tested. It is demonstrated that the method can be applied on samples with low chemical and optical purity, and that it may lend itself as a means to estimate the ee. The roles of the water content of the sample and of the diol-to-dimolybdenum ratio are investigated.
-
Determination of Absolute Configuration of Acyclic 1,2-Diols with Mo2(OAc)4. 1. Snatzke’s method revisited
'American Chemical Society (ACS)', 2001Co-Authors: Di Bari L, Pescitelli G, Pratelli C, Pini D, Salvadori PAbstract:The method employing dimolydbenum tetraacetate for the assignment of the absolute configuration of optically active 1,2-diols is thoroughly revisited and applied to several compounds, some of which were synthesized by asymmetric cis-dihydroxylation. No exceptions were found to the empirical rule relating the sign of the induced CD spectrum and the configuration of the substrate, whatever its structure and sterical requirements. To broaden the scope of the method, its applicability to critical situations commonly encountered with Synthetic Products is tested. It is demonstrated that the method can be applied on samples with low chemical and optical purity, and that it may lend itself as a means to estimate the ee. The roles of the water content of the sample and of the diol-to-dimolybdenum ratio are investigated
Kuo Hsiung Lee - One of the best experts on this subject based on the ideXlab platform.
-
synthesis and biological evaluation of chalcone dihydrochalcone and 1 3 diarylpropane analogs as anti inflammatory agents
Bioorganic & Medicinal Chemistry Letters, 2017Co-Authors: Mopur Vijaya Bhaskar Reddy, Ping Chung Kuo, Hsin Yi Hung, Guanjhong Huang, Yu Yi Chan, Shiow Chyn Huang, Susan L Morrisnatschke, Kuo Hsiung LeeAbstract:Twenty-one chalcones were prepared via aldol condensation and subsequent reduction of these compound led to the corresponding dihydrochalcone and 1,3-diphenylpropane derivatives. The Synthetic Products were examined for their effects on NO inhibition in LPS-activated mouse peritoneal macrophages. Among the tested compounds, a 1,3-diarylpropane analog, 2-(3-(3,4-dimethoxyphenyl)propyl)-5-methoxyphenol (3p), displayed the most significant inhibitory effects against NO production. To investigate the mechanism of action, the effects of 3p on iNOS and COX-2 protein expression were studied by immunoblot. The results concluded that 3p is capable of inhibiting iNOS expression in LPS-induced RAW264.7 cells via attenuation of NF-κB signaling by ERK, p38, and JNK.
Jizeng Song - One of the best experts on this subject based on the ideXlab platform.
-
a fast responsive fluorescent probe for detection of gold ions in water and Synthetic Products
ChemInform, 2011Co-Authors: Lin Yuan, Weiying Lin, Yueting Yang, Jizeng SongAbstract:A fast responsive fluorescent gold ion probe based on the unexpected gold ion-mediated hydrolysis of acylsemicarbazide (III) to the corresponding carboxylic acid is reported.
-
a fast responsive fluorescent probe for detection of gold ions in water and Synthetic Products
Chemical Communications, 2011Co-Authors: Lin Yuan, Weiying Lin, Yueting Yang, Jizeng SongAbstract:We have constructed a fast-responsive fluorescent gold ion probe based on the unexpected gold ion-mediated hydrolysis of acylsemicarbazides to carboxylic acids. The probe has been applied for sensing gold ions in the living cells and detecting residual gold content in gold-catalyzed Synthetic samples for the first time.
E. Primo-yúfera - One of the best experts on this subject based on the ideXlab platform.
-
Isolation of N-(2-methyl-3-oxodecanoyl)pyrrole and N-(2-methyl-3-oxodec-8-enoyl)pyrrole, two new natural Products from Penicillium brevicompactum, and synthesis of analogues with insecticidal and fungicidal activity
Journal of Agricultural and Food Chemistry, 1998Co-Authors: Angel Cantin, Pilar Moya, Jaime Primo, Miranda, E. Primo-yúferaAbstract:Two new natural Products have been isolated from culture broth of Penicillium brevicompactum Dierckx. The structures have been assigned as N-(2-methyl-3-oxodecanoyl)pyrrole and N-(2-methyl-3-oxodec-8-enoyl)pyrrole on the basis of spectral data. Synthesis of analogues has been carried out by acylation of the pyrrole ring at C2 with different acylated Meldrum's acids. Two analogues (6b and 7b) have shown interesting insecticidal activities, and three other ones (6a, 6c, and 7a) have exhibited significant broad-spectrum fungicidal activities. These Synthetic Products might be considered as a starting point in the search for new pesticides. Keywords: Penicillium brevicompactum; fungal metabolites; Meldrum's acid; 2-(3-oxoacyl)pyrrole; insecticide; fungicide
