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Douglas E Padgett - One of the best experts on this subject based on the ideXlab platform.

  • ceramic bearings with titanium adapter sleeves implanted during revision hip arthroplasty show minimal fretting or corrosion a retrieval analysis
    HSS Journal, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    Background The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions.

  • Ceramic Bearings with Titanium Adapter Sleeves Implanted During Revision Hip Arthroplasty Show Minimal Fretting or Corrosion: a Retrieval Analysis
    HSS Journal ®, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    Background The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions. Questions/Purposes The objective of this study was to identify the type and extent of damage to retrieved sleeves and ceramic heads to determine their in vivo performance. Methods Twenty-four ceramic heads with titanium alloy sleeves were examined. The articular and Taper surfaces for each ceramic head were assessed for metal transfer using a subjective grading system. All surfaces of the 24 titanium sleeves and stem trunnions (only available for 7 of 24 cases) were assessed for corrosion and fretting using an established grading system. Scanning electron microscopy and energy dispersive X-ray analysis were conducted on representative sample of sleeves. Results Fretting and corrosion were higher at the inner surface of the Taper sleeve than the outer sleeve. Mean fretting scores at the inner Taper and outer Taper sleeve surfaces were 1.8 and 1.2, respectively. The mean corrosion score at the inner Taper surface was 1.8; no corrosion was observed on the outer surface of any Taper sleeve. SEM and EDS analyses provided further indications of low levels of damage. Conclusion Fretting and corrosion were less severe than previously reported for conventional THA metal-metal Taper connections, indicating that a ceramic head and titanium sleeve is a safe alternative in revision THA.

  • ceramic bearings with titanium adapter sleeves implanted during revision hip arthroplasty show minimal fretting or corrosion a retrieval analysis
    HSS Journal, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions. The objective of this study was to identify the type and extent of damage to retrieved sleeves and ceramic heads to determine their in vivo performance. Twenty-four ceramic heads with titanium alloy sleeves were examined. The articular and Taper surfaces for each ceramic head were assessed for metal transfer using a subjective grading system. All surfaces of the 24 titanium sleeves and stem trunnions (only available for 7 of 24 cases) were assessed for corrosion and fretting using an established grading system. Scanning electron microscopy and energy dispersive X-ray analysis were conducted on representative sample of sleeves. Fretting and corrosion were higher at the inner surface of the Taper sleeve than the outer sleeve. Mean fretting scores at the inner Taper and outer Taper sleeve surfaces were 1.8 and 1.2, respectively. The mean corrosion score at the inner Taper surface was 1.8; no corrosion was observed on the outer surface of any Taper sleeve. SEM and EDS analyses provided further indications of low levels of damage. Fretting and corrosion were less severe than previously reported for conventional THA metal-metal Taper connections, indicating that a ceramic head and titanium sleeve is a safe alternative in revision THA.

Mark P Figgie - One of the best experts on this subject based on the ideXlab platform.

  • ceramic bearings with titanium adapter sleeves implanted during revision hip arthroplasty show minimal fretting or corrosion a retrieval analysis
    HSS Journal, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    Background The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions.

  • Ceramic Bearings with Titanium Adapter Sleeves Implanted During Revision Hip Arthroplasty Show Minimal Fretting or Corrosion: a Retrieval Analysis
    HSS Journal ®, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    Background The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions. Questions/Purposes The objective of this study was to identify the type and extent of damage to retrieved sleeves and ceramic heads to determine their in vivo performance. Methods Twenty-four ceramic heads with titanium alloy sleeves were examined. The articular and Taper surfaces for each ceramic head were assessed for metal transfer using a subjective grading system. All surfaces of the 24 titanium sleeves and stem trunnions (only available for 7 of 24 cases) were assessed for corrosion and fretting using an established grading system. Scanning electron microscopy and energy dispersive X-ray analysis were conducted on representative sample of sleeves. Results Fretting and corrosion were higher at the inner surface of the Taper sleeve than the outer sleeve. Mean fretting scores at the inner Taper and outer Taper sleeve surfaces were 1.8 and 1.2, respectively. The mean corrosion score at the inner Taper surface was 1.8; no corrosion was observed on the outer surface of any Taper sleeve. SEM and EDS analyses provided further indications of low levels of damage. Conclusion Fretting and corrosion were less severe than previously reported for conventional THA metal-metal Taper connections, indicating that a ceramic head and titanium sleeve is a safe alternative in revision THA.

  • ceramic bearings with titanium adapter sleeves implanted during revision hip arthroplasty show minimal fretting or corrosion a retrieval analysis
    HSS Journal, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions. The objective of this study was to identify the type and extent of damage to retrieved sleeves and ceramic heads to determine their in vivo performance. Twenty-four ceramic heads with titanium alloy sleeves were examined. The articular and Taper surfaces for each ceramic head were assessed for metal transfer using a subjective grading system. All surfaces of the 24 titanium sleeves and stem trunnions (only available for 7 of 24 cases) were assessed for corrosion and fretting using an established grading system. Scanning electron microscopy and energy dispersive X-ray analysis were conducted on representative sample of sleeves. Fretting and corrosion were higher at the inner surface of the Taper sleeve than the outer sleeve. Mean fretting scores at the inner Taper and outer Taper sleeve surfaces were 1.8 and 1.2, respectively. The mean corrosion score at the inner Taper surface was 1.8; no corrosion was observed on the outer surface of any Taper sleeve. SEM and EDS analyses provided further indications of low levels of damage. Fretting and corrosion were less severe than previously reported for conventional THA metal-metal Taper connections, indicating that a ceramic head and titanium sleeve is a safe alternative in revision THA.

Chelsea N Koch - One of the best experts on this subject based on the ideXlab platform.

  • ceramic bearings with titanium adapter sleeves implanted during revision hip arthroplasty show minimal fretting or corrosion a retrieval analysis
    HSS Journal, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    Background The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions.

  • Ceramic Bearings with Titanium Adapter Sleeves Implanted During Revision Hip Arthroplasty Show Minimal Fretting or Corrosion: a Retrieval Analysis
    HSS Journal ®, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    Background The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions. Questions/Purposes The objective of this study was to identify the type and extent of damage to retrieved sleeves and ceramic heads to determine their in vivo performance. Methods Twenty-four ceramic heads with titanium alloy sleeves were examined. The articular and Taper surfaces for each ceramic head were assessed for metal transfer using a subjective grading system. All surfaces of the 24 titanium sleeves and stem trunnions (only available for 7 of 24 cases) were assessed for corrosion and fretting using an established grading system. Scanning electron microscopy and energy dispersive X-ray analysis were conducted on representative sample of sleeves. Results Fretting and corrosion were higher at the inner surface of the Taper sleeve than the outer sleeve. Mean fretting scores at the inner Taper and outer Taper sleeve surfaces were 1.8 and 1.2, respectively. The mean corrosion score at the inner Taper surface was 1.8; no corrosion was observed on the outer surface of any Taper sleeve. SEM and EDS analyses provided further indications of low levels of damage. Conclusion Fretting and corrosion were less severe than previously reported for conventional THA metal-metal Taper connections, indicating that a ceramic head and titanium sleeve is a safe alternative in revision THA.

  • ceramic bearings with titanium adapter sleeves implanted during revision hip arthroplasty show minimal fretting or corrosion a retrieval analysis
    HSS Journal, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions. The objective of this study was to identify the type and extent of damage to retrieved sleeves and ceramic heads to determine their in vivo performance. Twenty-four ceramic heads with titanium alloy sleeves were examined. The articular and Taper surfaces for each ceramic head were assessed for metal transfer using a subjective grading system. All surfaces of the 24 titanium sleeves and stem trunnions (only available for 7 of 24 cases) were assessed for corrosion and fretting using an established grading system. Scanning electron microscopy and energy dispersive X-ray analysis were conducted on representative sample of sleeves. Fretting and corrosion were higher at the inner surface of the Taper sleeve than the outer sleeve. Mean fretting scores at the inner Taper and outer Taper sleeve surfaces were 1.8 and 1.2, respectively. The mean corrosion score at the inner Taper surface was 1.8; no corrosion was observed on the outer surface of any Taper sleeve. SEM and EDS analyses provided further indications of low levels of damage. Fretting and corrosion were less severe than previously reported for conventional THA metal-metal Taper connections, indicating that a ceramic head and titanium sleeve is a safe alternative in revision THA.

  • fretting and corrosion at the backside of modular cobalt chromium acetabular inserts a retrieval analysis
    Journal of Arthroplasty, 2017
    Co-Authors: David T Tarity, Chelsea N Koch, Jayme C Burket, Timothy M Wright, Geoffrey H Westrich
    Abstract:

    Abstract Background Adverse local tissue reaction formation has been suggested to occur with the Modular Dual Mobility (MDM) acetabular design. Few reports in the literature have evaluated fretting and corrosion damage between the acetabular shell and modular metal inserts in this modular system. We evaluated a series of 18 retrieved cobalt chromium MDM inserts for evidence of fretting and corrosion. Methods We assessed the backsides of 18 MDM components for evidence of fretting and corrosion in polar and Taper Regions based on previously established methods. We collected and assessed 30 similarly designed modular inserts retrieved from metal-on-metal (MoM) total hip arthroplasties as a control. Results No specific pattern of fretting or corrosion was identified on the MDM inserts. Both fretting and corrosion were significantly greater in the MoM cohort than the MDM cohort, driven by higher fretting and corrosion scores in the engaged Taper Region of the MoM inserts. Conclusion MoM components demonstrated more fretting and corrosion than MDM designs, specifically at the Taper Region, likely driven by differences in the Taper engagement mechanism and geometry among the insert designs. The lack of significant fretting and corrosion observed in the MDM inserts are inconsistent with recent claims that this interface may produce clinically significant metallosis and adverse local tissue reactions.

Willy Wriggers - One of the best experts on this subject based on the ideXlab platform.

  • A cryo-tomography-based volumetric model of the actin core of mouse vestibular hair cell stereocilia lacking plastin 1.
    Journal of structural biology, 2020
    Co-Authors: Junha Song, Roma Patterson, Jocelyn F. Krey, Samantha Hao, Linshanshan Wang, Salim Sazzed, Julio A. Kovacs, Zoltan Metlagel, Willy Wriggers
    Abstract:

    Abstract Electron cryo-tomography allows for high-resolution imaging of stereocilia in their native state. Because their actin filaments have a higher degree of order, we imaged stereocilia from mice lacking the actin crosslinker plastin 1 (PLS1). We found that while stereocilia actin filaments run 13 nm apart in parallel for long distances, there were gaps of significant size that were stochastically distributed throughout the actin core. Actin crosslinkers were distributed through the stereocilium, but did not occupy all possible binding sites. At stereocilia tips, protein density extended beyond actin filaments, especially on the side of the tip where a tip link is expected to anchor. Along the shaft, repeating density was observed that corresponds to actin-to-membrane connectors. In the Taper Region, most actin filaments terminated near the plasma membrane. The remaining filaments twisted together to make a tighter bundle than was present in the shaft Region; the spacing between them decreased from 13 nm to 9 nm, and the apparent filament diameter decreased from 6.4 to 4.8 nm. Our models illustrate detailed features of distinct structural domains that are present within the stereocilium.

  • A cryo-tomography-based volumetric model of the actin core of mouse vestibular hair cell stereocilia lacking plastin 1
    2019
    Co-Authors: Junha Song, Roma Patterson, Jocelyn F. Krey, Samantha Hao, Linshanshan Wang, Salim Sazzed, Julio A. Kovacs, Willy Wriggers
    Abstract:

    Electron cryo-tomography allows for high-resolution imaging of stereocilia in their native state. Because their actin filaments have a higher degree of order, we imaged stereocilia from mice lacking the actin crosslinker plastin 1 (PLS1). We found that while stereocilia actin filaments run in parallel for long distances, 13 nm apart, there were gaps of significant size that were stochastically distributed throughout the actin core. Actin crosslinkers were distributed through the stereocilium, but did not occupy all possible binding sites. At stereocilia tips, protein density extended beyond actin filaments, especially on the side of the tip where a tip link should anchor. Along the shaft, repeating density was observed that corresponds to actin-to-membrane connectors. In the Taper Region, most actin filaments terminated near the plasma membrane. The remaining filaments twisted together to make a tighter bundle than was present in the shaft Region; the spacing between them decreased from 13 nm to 9 nm. Our models illustrate detailed features of distinct structural domains that are present within the stereocilium.

Timothy M Wright - One of the best experts on this subject based on the ideXlab platform.

  • ceramic bearings with titanium adapter sleeves implanted during revision hip arthroplasty show minimal fretting or corrosion a retrieval analysis
    HSS Journal, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    Background The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions.

  • Ceramic Bearings with Titanium Adapter Sleeves Implanted During Revision Hip Arthroplasty Show Minimal Fretting or Corrosion: a Retrieval Analysis
    HSS Journal ®, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    Background The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions. Questions/Purposes The objective of this study was to identify the type and extent of damage to retrieved sleeves and ceramic heads to determine their in vivo performance. Methods Twenty-four ceramic heads with titanium alloy sleeves were examined. The articular and Taper surfaces for each ceramic head were assessed for metal transfer using a subjective grading system. All surfaces of the 24 titanium sleeves and stem trunnions (only available for 7 of 24 cases) were assessed for corrosion and fretting using an established grading system. Scanning electron microscopy and energy dispersive X-ray analysis were conducted on representative sample of sleeves. Results Fretting and corrosion were higher at the inner surface of the Taper sleeve than the outer sleeve. Mean fretting scores at the inner Taper and outer Taper sleeve surfaces were 1.8 and 1.2, respectively. The mean corrosion score at the inner Taper surface was 1.8; no corrosion was observed on the outer surface of any Taper sleeve. SEM and EDS analyses provided further indications of low levels of damage. Conclusion Fretting and corrosion were less severe than previously reported for conventional THA metal-metal Taper connections, indicating that a ceramic head and titanium sleeve is a safe alternative in revision THA.

  • ceramic bearings with titanium adapter sleeves implanted during revision hip arthroplasty show minimal fretting or corrosion a retrieval analysis
    HSS Journal, 2017
    Co-Authors: Chelsea N Koch, Timothy M Wright, Mark P Figgie, Marcella E Elpers, Douglas E Padgett
    Abstract:

    The BIOLOX® option system, consisting of a BIOLOX® delta ceramic femoral head with a titanium alloy adapter sleeve, is being increasingly utilized in revision hip arthroplasty. The sleeve protects the ceramic head from fracture and improper motion about the stem trunnion when a damaged trunnion is encountered at revision surgery. Corrosion and fretting due to metal-metal contact at the Taper Region of hip prosthesis create the potential of causing periprosthetic osteolysis and adverse local tissue reactions. The objective of this study was to identify the type and extent of damage to retrieved sleeves and ceramic heads to determine their in vivo performance. Twenty-four ceramic heads with titanium alloy sleeves were examined. The articular and Taper surfaces for each ceramic head were assessed for metal transfer using a subjective grading system. All surfaces of the 24 titanium sleeves and stem trunnions (only available for 7 of 24 cases) were assessed for corrosion and fretting using an established grading system. Scanning electron microscopy and energy dispersive X-ray analysis were conducted on representative sample of sleeves. Fretting and corrosion were higher at the inner surface of the Taper sleeve than the outer sleeve. Mean fretting scores at the inner Taper and outer Taper sleeve surfaces were 1.8 and 1.2, respectively. The mean corrosion score at the inner Taper surface was 1.8; no corrosion was observed on the outer surface of any Taper sleeve. SEM and EDS analyses provided further indications of low levels of damage. Fretting and corrosion were less severe than previously reported for conventional THA metal-metal Taper connections, indicating that a ceramic head and titanium sleeve is a safe alternative in revision THA.

  • fretting and corrosion at the backside of modular cobalt chromium acetabular inserts a retrieval analysis
    Journal of Arthroplasty, 2017
    Co-Authors: David T Tarity, Chelsea N Koch, Jayme C Burket, Timothy M Wright, Geoffrey H Westrich
    Abstract:

    Abstract Background Adverse local tissue reaction formation has been suggested to occur with the Modular Dual Mobility (MDM) acetabular design. Few reports in the literature have evaluated fretting and corrosion damage between the acetabular shell and modular metal inserts in this modular system. We evaluated a series of 18 retrieved cobalt chromium MDM inserts for evidence of fretting and corrosion. Methods We assessed the backsides of 18 MDM components for evidence of fretting and corrosion in polar and Taper Regions based on previously established methods. We collected and assessed 30 similarly designed modular inserts retrieved from metal-on-metal (MoM) total hip arthroplasties as a control. Results No specific pattern of fretting or corrosion was identified on the MDM inserts. Both fretting and corrosion were significantly greater in the MoM cohort than the MDM cohort, driven by higher fretting and corrosion scores in the engaged Taper Region of the MoM inserts. Conclusion MoM components demonstrated more fretting and corrosion than MDM designs, specifically at the Taper Region, likely driven by differences in the Taper engagement mechanism and geometry among the insert designs. The lack of significant fretting and corrosion observed in the MDM inserts are inconsistent with recent claims that this interface may produce clinically significant metallosis and adverse local tissue reactions.