The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform
Glen E Foster - One of the best experts on this subject based on the ideXlab platform.
-
measuring the human ventilatory and cerebral blood flow response to co2 a Technical Consideration for the end tidal to arterial gas gradient
Journal of Applied Physiology, 2016Co-Authors: Michael M Tymko, Ryan L Hoiland, Tomas Kuca, Lindsey M Boulet, Joshua C Tremblay, Bryenna K Pinske, Alexandra M Williams, Glen E FosterAbstract:Our aim was to quantify the end-tidal-to-arterial gas gradients for O2 (PET-PaO2) and CO2 (Pa-PETCO2) during a CO2 reactivity test to determine their influence on the cerebrovascular (CVR) and vent...
-
measuring the human ventilatory and cerebral blood flow response to co2 a Technical Consideration for the end tidal to arterial gas gradient
Journal of Applied Physiology, 2016Co-Authors: Michael M Tymko, Ryan L Hoiland, Tomas Kuca, Lindsey M Boulet, Joshua C Tremblay, Bryenna K Pinske, Alexandra M Williams, Glen E FosterAbstract:Our aim was to quantify the end-tidal-to-arterial gas gradients for O2 (PET-PaO2) and CO2 (Pa-PETCO2) during a CO2 reactivity test to determine their influence on the cerebrovascular (CVR) and ventilatory (HCVR) response in subjects with (PFO+, n = 8) and without (PFO-, n = 7) a patent foramen ovale (PFO). We hypothesized that 1) the Pa-PETCO2 would be greater in hypoxia compared with normoxia, 2) the Pa-PETCO2 would be similar, whereas the PET-PaO2 gradient would be greater in those with a PFO, 3) the HCVR and CVR would be underestimated when plotted against PETCO2 compared with PaCO2, and 4) previously derived prediction algorithms will accurately target PaCO2. PETCO2 was controlled by dynamic end-tidal forcing in steady-state steps of -8, -4, 0, +4, and +8 mmHg from baseline in normoxia and hypoxia. Minute ventilation (VE), internal carotid artery blood flow (QICA), middle cerebral artery blood velocity (MCAv), and temperature corrected end-tidal and arterial blood gases were measured throughout experimentation. HCVR and CVR were calculated using linear regression analysis by indexing VE and relative changes in QICA, and MCAv against PETCO2, predicted PaCO2, and measured PaCO2. The Pa-PETCO2 was similar between hypoxia and normoxia and PFO+ and PFO-. The PET-PaO2 was greater in PFO+ by 2.1 mmHg during normoxia (P = 0.003). HCVR and CVR plotted against PETCO2 underestimated HCVR and CVR indexed against PaCO2 in normoxia and hypoxia. Our PaCO2 prediction equation modestly improved estimates of HCVR and CVR. In summary, care must be taken when indexing reactivity measures to PETCO2 compared with PaCO2.
Michael M Tymko - One of the best experts on this subject based on the ideXlab platform.
-
measuring the human ventilatory and cerebral blood flow response to co2 a Technical Consideration for the end tidal to arterial gas gradient
Journal of Applied Physiology, 2016Co-Authors: Michael M Tymko, Ryan L Hoiland, Tomas Kuca, Lindsey M Boulet, Joshua C Tremblay, Bryenna K Pinske, Alexandra M Williams, Glen E FosterAbstract:Our aim was to quantify the end-tidal-to-arterial gas gradients for O2 (PET-PaO2) and CO2 (Pa-PETCO2) during a CO2 reactivity test to determine their influence on the cerebrovascular (CVR) and vent...
-
measuring the human ventilatory and cerebral blood flow response to co2 a Technical Consideration for the end tidal to arterial gas gradient
Journal of Applied Physiology, 2016Co-Authors: Michael M Tymko, Ryan L Hoiland, Tomas Kuca, Lindsey M Boulet, Joshua C Tremblay, Bryenna K Pinske, Alexandra M Williams, Glen E FosterAbstract:Our aim was to quantify the end-tidal-to-arterial gas gradients for O2 (PET-PaO2) and CO2 (Pa-PETCO2) during a CO2 reactivity test to determine their influence on the cerebrovascular (CVR) and ventilatory (HCVR) response in subjects with (PFO+, n = 8) and without (PFO-, n = 7) a patent foramen ovale (PFO). We hypothesized that 1) the Pa-PETCO2 would be greater in hypoxia compared with normoxia, 2) the Pa-PETCO2 would be similar, whereas the PET-PaO2 gradient would be greater in those with a PFO, 3) the HCVR and CVR would be underestimated when plotted against PETCO2 compared with PaCO2, and 4) previously derived prediction algorithms will accurately target PaCO2. PETCO2 was controlled by dynamic end-tidal forcing in steady-state steps of -8, -4, 0, +4, and +8 mmHg from baseline in normoxia and hypoxia. Minute ventilation (VE), internal carotid artery blood flow (QICA), middle cerebral artery blood velocity (MCAv), and temperature corrected end-tidal and arterial blood gases were measured throughout experimentation. HCVR and CVR were calculated using linear regression analysis by indexing VE and relative changes in QICA, and MCAv against PETCO2, predicted PaCO2, and measured PaCO2. The Pa-PETCO2 was similar between hypoxia and normoxia and PFO+ and PFO-. The PET-PaO2 was greater in PFO+ by 2.1 mmHg during normoxia (P = 0.003). HCVR and CVR plotted against PETCO2 underestimated HCVR and CVR indexed against PaCO2 in normoxia and hypoxia. Our PaCO2 prediction equation modestly improved estimates of HCVR and CVR. In summary, care must be taken when indexing reactivity measures to PETCO2 compared with PaCO2.
Changwoo Ryu - One of the best experts on this subject based on the ideXlab platform.
-
staged endovascular occlusion of a posterior communicating artery cavernous sinus fistula and a basilar artery cavernous sinus fistula associated with traumatic pseudoaneurysms Technical Consideration and literature review
World Neurosurgery, 2017Co-Authors: Jun Seok Koh, Hee Sup Shin, Seung Hwan Lee, Changwoo RyuAbstract:Background Traumatic injury of the posterior communicating artery or the basilar artery causing arteriovenous fistulae is rare. Case Description Here we report an unusual case of the coincidence of a posterior communicating artery-cavernous sinus fistula and a basilar artery-cavernous sinus fistula associated with traumatic pseudoaneurysms of the posterior communicating and basilar arteries. The fistulas and pseudoaneurysms were obliterated completely after staged endovascular surgery via a transarterial and transvenous route. Conclusions To our knowledge, this is the first such report worldwide.
Wei Chiang Liu - One of the best experts on this subject based on the ideXlab platform.
-
transforaminal percutaneous endoscopic lumbar discectomy for upper lumbar disc herniation clinical outcome prognostic factors and Technical Consideration
Acta Neurochirurgica, 2009Co-Authors: Yong Ahn, Sangho Lee, June Ho Lee, Jin Uk Kim, Wei Chiang LiuAbstract:Background Compared with lower lumbar disc herniations, upper lumbar disc herniations at L1–L2 and L2–L3 have specific characteristics that result in different surgical outcomes after conventional open discectomy. There are no published studies on the feasibility of percutaneous endoscopic lumbar discectomy for upper lumbar disc herniation. The purpose of this study was to assess the clinical outcome, prognostic factors and the Technical pitfalls of PELD for upper lumbar disc herniation.
-
transforaminal percutaneous endoscopic lumbar discectomy for upper lumbar disc herniation clinical outcome prognostic factors and Technical Consideration
Acta Neurochirurgica, 2009Co-Authors: Yong Ahn, Sangho Lee, June Ho Lee, Jin Uk Kim, Wei Chiang LiuAbstract:Compared with lower lumbar disc herniations, upper lumbar disc herniations at L1–L2 and L2–L3 have specific characteristics that result in different surgical outcomes after conventional open discectomy. There are no published studies on the feasibility of percutaneous endoscopic lumbar discectomy for upper lumbar disc herniation. The purpose of this study was to assess the clinical outcome, prognostic factors and the Technical pitfalls of PELD for upper lumbar disc herniation. Forty-five patients with a soft disc herniation at L1–L2 or L2–L3 underwent percutaneous endoscopic discectomy. Posterolateral transforaminal endoscopic laser-assisted disc removal was performed under local anesthesia. Clinical outcomes was assessed using the Prolo scale. The prognostic factors associated with outcome were then analyzed. The mean follow-up was 38.8 months (range, 25–52 months). The outcome of the 45 patients was excellent in 21 (46.7%), good in 14 patients (31.1%), fair in six patients (13.3%), and poor in four patients (8.9%). Four patients with a poor outcome underwent further open surgery. Mean scores on a visual analog scale decreased from 8.38 to 2.36 (P < 0.0001). Age less than 45 years and a lateral disc herniation were independently associated with an excellent outcome (P < 0.05). Patient selection and an anatomically modified surgical technique promote a more successful outcome after percutaneous endoscopic discectomy for upper lumbar disc herniation.
Bryenna K Pinske - One of the best experts on this subject based on the ideXlab platform.
-
measuring the human ventilatory and cerebral blood flow response to co2 a Technical Consideration for the end tidal to arterial gas gradient
Journal of Applied Physiology, 2016Co-Authors: Michael M Tymko, Ryan L Hoiland, Tomas Kuca, Lindsey M Boulet, Joshua C Tremblay, Bryenna K Pinske, Alexandra M Williams, Glen E FosterAbstract:Our aim was to quantify the end-tidal-to-arterial gas gradients for O2 (PET-PaO2) and CO2 (Pa-PETCO2) during a CO2 reactivity test to determine their influence on the cerebrovascular (CVR) and vent...
-
measuring the human ventilatory and cerebral blood flow response to co2 a Technical Consideration for the end tidal to arterial gas gradient
Journal of Applied Physiology, 2016Co-Authors: Michael M Tymko, Ryan L Hoiland, Tomas Kuca, Lindsey M Boulet, Joshua C Tremblay, Bryenna K Pinske, Alexandra M Williams, Glen E FosterAbstract:Our aim was to quantify the end-tidal-to-arterial gas gradients for O2 (PET-PaO2) and CO2 (Pa-PETCO2) during a CO2 reactivity test to determine their influence on the cerebrovascular (CVR) and ventilatory (HCVR) response in subjects with (PFO+, n = 8) and without (PFO-, n = 7) a patent foramen ovale (PFO). We hypothesized that 1) the Pa-PETCO2 would be greater in hypoxia compared with normoxia, 2) the Pa-PETCO2 would be similar, whereas the PET-PaO2 gradient would be greater in those with a PFO, 3) the HCVR and CVR would be underestimated when plotted against PETCO2 compared with PaCO2, and 4) previously derived prediction algorithms will accurately target PaCO2. PETCO2 was controlled by dynamic end-tidal forcing in steady-state steps of -8, -4, 0, +4, and +8 mmHg from baseline in normoxia and hypoxia. Minute ventilation (VE), internal carotid artery blood flow (QICA), middle cerebral artery blood velocity (MCAv), and temperature corrected end-tidal and arterial blood gases were measured throughout experimentation. HCVR and CVR were calculated using linear regression analysis by indexing VE and relative changes in QICA, and MCAv against PETCO2, predicted PaCO2, and measured PaCO2. The Pa-PETCO2 was similar between hypoxia and normoxia and PFO+ and PFO-. The PET-PaO2 was greater in PFO+ by 2.1 mmHg during normoxia (P = 0.003). HCVR and CVR plotted against PETCO2 underestimated HCVR and CVR indexed against PaCO2 in normoxia and hypoxia. Our PaCO2 prediction equation modestly improved estimates of HCVR and CVR. In summary, care must be taken when indexing reactivity measures to PETCO2 compared with PaCO2.
