The Experts below are selected from a list of 105 Experts worldwide ranked by ideXlab platform
Ahmet Rifat Sahin - One of the best experts on this subject based on the ideXlab platform.
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Temperament and character Traits in patients with bipolar disorder and associations with attempted suicide
Comprehensive Psychiatry, 2012Co-Authors: Gokhan Sarisoy, Omer Faruk Kacar, Ozan Pazvantoglu, Arif Ozturk, Isil Zabun Korkmaz, Birsen Kocamanoglu, Omer Boke, Ahmet Rifat SahinAbstract:Abstract Objective This study was intended to investigate Temperament and character Traits in bipolar disorder patients with or without a history of attempted suicide. Methods One hundred nineteen patients diagnosed with euthymic bipolar disorder based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision , and with no accompanying Axis I and II comorbidity, and 103 healthy controls were included. Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition , Axis I and II disorders were used to exclude Axis I and II comorbidity. Temperament and character Traits of bipolar patients with a history attempted suicide (25.2%, n=30) or without (74.8%, n=89) and of the healthy volunteers were determined using the Temperament and Character Inventory. The association between current suicide ideation and Temperament and character Traits was also examined. Results Bipolar patients with or without a history of attempted suicide had higher harm avoidance (HA) scores compared with the healthy controls. Persistence scores of bipolar patients with no history of attempted suicide were lower than those of the healthy controls. Self-directedness (SD) scores of the bipolar patients with a history of attempted suicide were lower than those of patients with no such history. Self-transcendence scores of bipolar patients with no history of attempted suicide were lower than those of both the healthy controls and of those patients with a history of attempted suicide. A positive correlation was determined between current suicidal ideation scale scores and HA, and a negative correlation between SD and cooperativeness was determined. Conclusions High harm avoidance may be a Temperament Trait specific to bipolar disorder patients. However, it may not be correlated with attempted suicide in such patients. These may have low persistence, high SD and low self-transcendence Temperament and character Traits that protect against attempted suicide. Harm avoidance, SD, and cooperativeness may be correlated with current suicidal ideation.
Ming Song - One of the best experts on this subject based on the ideXlab platform.
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Connectome-based individualized prediction of Temperament Trait scores.
NeuroImage, 2018Co-Authors: Rongtao Jiang, Shile Qi, Zening Fu, Vince D. Calhoun, Jin Li, Ming SongAbstract:Abstract Temperament consists of multi-dimensional Traits that affect various domains of human life. Evidence has shown functional connectome-based predictive models are powerful predictors of cognitive abilities. Putatively, individuals' innate Temperament Traits may be predictable by unique patterns of brain functional connectivity (FC) as well. However, quantitative prediction for multiple Temperament Traits at the individual level has not yet been studied. Therefore, we were motivated to realize the individualized prediction of four Temperament Traits (novelty seeking [NS], harm avoidance [HA], reward dependence [RD] and persistence [PS]) using whole-brain FC. Specifically, a multivariate prediction framework integrating feature selection and sparse regression was applied to resting-state fMRI data from 360 college students, resulting in 4 connectome-based predictive models that enabled prediction of Temperament scores for unseen subjects in cross-validation. More importantly, predictive models for HA and NS could be successfully generalized to two relevant personality Traits for unseen individuals, i.e., neuroticism and extraversion, in an independent dataset. In four Temperament Trait predictions, brain connectivities that show top contributing power commonly concentrated on the hippocampus, prefrontal cortex, basal ganglia, amygdala, and cingulate gyrus. Finally, across independent datasets and multiple Traits, we show person's Temperament Traits can be reliably predicted using functional connectivity strength within frontal-subcortical circuits, indicating that human social and behavioral performance can be characterized by specific brain connectivity profile.
E I Rogaev - One of the best experts on this subject based on the ideXlab platform.
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insertion deletion polymorphism of the serotonin transporter gene and neuroticism as a Temperament Trait in affective patients and healthy individuals
Molecular Biology, 2001Co-Authors: V E Golimbet, M V Alfimova, T V Shcherbatykh, L I Abramova, V G Kaleda, E I RogaevAbstract:Some studies associate the insertion/deletion polymorphism of the serotonin transporter (5-HTT) gene with anxiety-related personality Traits in mentally healthy people, the short (s) allele being associated with a higher neuroticism score. The 5-HTT genotype and neuroticism score were established for 114 affective patients, 87 healthy relatives of endogenous psychosis patients, and for 156 mentally healthy people without familial psychiatric history. The effects of sex and age on the association between the two parameters was studied. Neuroticism proved to be not associated with the 5-HTT genotype.
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insertion deletion polymorphism of the serotonin carrier gene and evaluation of neurotism as a Temperament Trait in patients with affective disorders and mentally healthy people
Molecular Biology, 2001Co-Authors: V E Golimbet, T V Shcherbatykh, L I Abramova, V G Kaleda, V M Alfimova, E I RogaevAbstract:Some studies associate the insertion/deletion polymorphism of the serotonin transporter (5-HTT) gene with anxiety-related personality Traits in mentally healthy people, the short (s) allele being associated with a higher neuroticism score. The 5-HTT genotype and neuroticism score were established for 114 affective patients, 87 healthy relatives of endogenous psychosis patients, and for 156 mentally healthy people without familial psychiatric history. The effects of sex and age on the association between the two parameters was studied. Neuroticism proved to be not associated with the 5-HTT genotype.
Gokhan Sarisoy - One of the best experts on this subject based on the ideXlab platform.
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Temperament and character Traits in patients with bipolar disorder and associations with attempted suicide
Comprehensive Psychiatry, 2012Co-Authors: Gokhan Sarisoy, Omer Faruk Kacar, Ozan Pazvantoglu, Arif Ozturk, Isil Zabun Korkmaz, Birsen Kocamanoglu, Omer Boke, Ahmet Rifat SahinAbstract:Abstract Objective This study was intended to investigate Temperament and character Traits in bipolar disorder patients with or without a history of attempted suicide. Methods One hundred nineteen patients diagnosed with euthymic bipolar disorder based on Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision , and with no accompanying Axis I and II comorbidity, and 103 healthy controls were included. Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition , Axis I and II disorders were used to exclude Axis I and II comorbidity. Temperament and character Traits of bipolar patients with a history attempted suicide (25.2%, n=30) or without (74.8%, n=89) and of the healthy volunteers were determined using the Temperament and Character Inventory. The association between current suicide ideation and Temperament and character Traits was also examined. Results Bipolar patients with or without a history of attempted suicide had higher harm avoidance (HA) scores compared with the healthy controls. Persistence scores of bipolar patients with no history of attempted suicide were lower than those of the healthy controls. Self-directedness (SD) scores of the bipolar patients with a history of attempted suicide were lower than those of patients with no such history. Self-transcendence scores of bipolar patients with no history of attempted suicide were lower than those of both the healthy controls and of those patients with a history of attempted suicide. A positive correlation was determined between current suicidal ideation scale scores and HA, and a negative correlation between SD and cooperativeness was determined. Conclusions High harm avoidance may be a Temperament Trait specific to bipolar disorder patients. However, it may not be correlated with attempted suicide in such patients. These may have low persistence, high SD and low self-transcendence Temperament and character Traits that protect against attempted suicide. Harm avoidance, SD, and cooperativeness may be correlated with current suicidal ideation.
James J. Hudziak - One of the best experts on this subject based on the ideXlab platform.
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interactions between child and parent Temperament and child behavior problems
Comprehensive Psychiatry, 2006Co-Authors: David C. Rettew, Catherine Stanger, Alicia Doyle, Laura G Mckee, James J. HudziakAbstract:Abstract Objective Few studies of Temperament have tested goodness-of-fit theories of child behavior problems. In this study, we test the hypothesis that interactions between child and parent Temperament dimensions predict levels of child psychopathology after controlling for the effects of these dimensions individually. Methods Temperament and psychopathology were assessed in a total of 175 children (97 boys, 78 girls; mean age, 10.99 years; SD, 3.66 years) using composite scores from multiple informants of the Junior Temperament and Character Inventory and the Achenbach System of Empirically Based Assessment. Parent Temperament was assessed using the adult version of the Temperament and Character Inventory. Statistical analyses included multiple regression procedures to assess the contribution of child-parent Temperament interactions after controlling for demographic variables, other types of child psychopathology, and the individual Temperament and Character Inventory and Junior Temperament and Character Inventory dimensions. Results Interactions between child and parent Temperament dimensions predicted higher levels of externalizing, internalizing, and attention problems over and above the effects of these dimensions alone. Among others, the combination of high child novelty seeking with high maternal novelty was associated with child attention problems, whereas the combination of high child harm avoidance and high father harm avoidance was associated with increased child internalizing problems. Many child Temperament dimensions also exerted significant effects independently. Conclusions The association between a child Temperament Trait and psychopathology can be dependent upon the Temperament of parents. These data lend support to previous theories of the importance of goodness-of-fit.
