The Experts below are selected from a list of 195 Experts worldwide ranked by ideXlab platform

Adhi Pribadi - One of the best experts on this subject based on the ideXlab platform.

  • The Teratogenic Effect of The Mindi (Melia azedarach L) Leaves Ethanol Extract on Mice (Mus musculus) Fetus
    Althea Medical Journal, 2015
    Co-Authors: Adisti Erlina Sutomo, Trully D. Sitorus, Adhi Pribadi
    Abstract:

    Background : Mindi leaves (Melia azeradach L.) were used by Indonesians as a traditional medicine for pregnant women because it was considered to be safe. Mindi leaves contain several active compounds and one of them is suspected as a teratogen and can disrupt fetus growth in gestation. This research aims to know about the Teratogenic Effect of ethanol extract of Mindi leaves by using mice. Methods : This was a laboratory experimental study using 27 pregnant female mice (Mus musculus) of Swiss Webster strain which were randomly assigned to 3 groups (n=9) controlled (Carboxymethyl cellulose 1% for day 1–18 of pregnancy), group I (mindi leaves ethanol extract 3.22 mg+Carboxymethyl cellulose 1% day 1–5 of pregnancy), and group II (mindi leaves ethanol extract 3.22 mg+Carboxymethyl cellulose 1% day 6–18 of pregnancy). Observation was done to see total amount of fetus, live normal fetus count, length and weight of fetus, abnormal fetus count consisting of dead fetus count with normal and abnormal external morphology, and resorbed fetus count. This research was done from October to November 2012 in Pharmacological laboratory of Faculty of Medicine Universitas Padjajdjaran. Data analysis utilized unpaired t-test. Results : The result showed a significant difference (p

Adisti Erlina Sutomo - One of the best experts on this subject based on the ideXlab platform.

  • The Teratogenic Effect of The Mindi (Melia azedarach L) Leaves Ethanol Extract on Mice (Mus musculus) Fetus
    Althea Medical Journal, 2015
    Co-Authors: Adisti Erlina Sutomo, Trully D. Sitorus, Adhi Pribadi
    Abstract:

    Background : Mindi leaves (Melia azeradach L.) were used by Indonesians as a traditional medicine for pregnant women because it was considered to be safe. Mindi leaves contain several active compounds and one of them is suspected as a teratogen and can disrupt fetus growth in gestation. This research aims to know about the Teratogenic Effect of ethanol extract of Mindi leaves by using mice. Methods : This was a laboratory experimental study using 27 pregnant female mice (Mus musculus) of Swiss Webster strain which were randomly assigned to 3 groups (n=9) controlled (Carboxymethyl cellulose 1% for day 1–18 of pregnancy), group I (mindi leaves ethanol extract 3.22 mg+Carboxymethyl cellulose 1% day 1–5 of pregnancy), and group II (mindi leaves ethanol extract 3.22 mg+Carboxymethyl cellulose 1% day 6–18 of pregnancy). Observation was done to see total amount of fetus, live normal fetus count, length and weight of fetus, abnormal fetus count consisting of dead fetus count with normal and abnormal external morphology, and resorbed fetus count. This research was done from October to November 2012 in Pharmacological laboratory of Faculty of Medicine Universitas Padjajdjaran. Data analysis utilized unpaired t-test. Results : The result showed a significant difference (p

Niels Graem - One of the best experts on this subject based on the ideXlab platform.

  • Lung hypoplasia – a possible Teratogenic Effect of valproate
    APMIS : acta pathologica microbiologica et immunologica Scandinavica, 1998
    Co-Authors: Mette Stagaard Janas, Mette Arrøe, Steen Holger Hansen, Niels Graem
    Abstract:

    Three cases of lung hypoplasia occurring in two siblings and in an unrelated child are reported. All three cases had been exposed to valproate in utero. The two female siblings had no other malformations, whereas the third female had a number of defects consistent with the fetal valproate syndrome. Thus, none of the known major causes of lung hypoplasia was present in any of the three cases. It is discussed whether pulmonary hypoplasia may be a separate disease entity, or caused by prenatal exposure to valproate.

  • lung hypoplasia a possible Teratogenic Effect of valproate
    Apmis, 1998
    Co-Authors: Mette Stagaard Janas, Mette Arrøe, Steen Holger Hansen, Niels Graem
    Abstract:

    Three cases of lung hypoplasia occurring in two siblings and in an unrelated child are reported. All three cases had been exposed to valproate in utero. The two female siblings had no other malformations, whereas the third female had a number of defects consistent with the fetal valproate syndrome. Thus, none of the known major causes of lung hypoplasia was present in any of the three cases. It is discussed whether pulmonary hypoplasia may be a separate disease entity, or caused by prenatal exposure to valproate.

Trully D. Sitorus - One of the best experts on this subject based on the ideXlab platform.

  • The Teratogenic Effect of The Mindi (Melia azedarach L) Leaves Ethanol Extract on Mice (Mus musculus) Fetus
    Althea Medical Journal, 2015
    Co-Authors: Adisti Erlina Sutomo, Trully D. Sitorus, Adhi Pribadi
    Abstract:

    Background : Mindi leaves (Melia azeradach L.) were used by Indonesians as a traditional medicine for pregnant women because it was considered to be safe. Mindi leaves contain several active compounds and one of them is suspected as a teratogen and can disrupt fetus growth in gestation. This research aims to know about the Teratogenic Effect of ethanol extract of Mindi leaves by using mice. Methods : This was a laboratory experimental study using 27 pregnant female mice (Mus musculus) of Swiss Webster strain which were randomly assigned to 3 groups (n=9) controlled (Carboxymethyl cellulose 1% for day 1–18 of pregnancy), group I (mindi leaves ethanol extract 3.22 mg+Carboxymethyl cellulose 1% day 1–5 of pregnancy), and group II (mindi leaves ethanol extract 3.22 mg+Carboxymethyl cellulose 1% day 6–18 of pregnancy). Observation was done to see total amount of fetus, live normal fetus count, length and weight of fetus, abnormal fetus count consisting of dead fetus count with normal and abnormal external morphology, and resorbed fetus count. This research was done from October to November 2012 in Pharmacological laboratory of Faculty of Medicine Universitas Padjajdjaran. Data analysis utilized unpaired t-test. Results : The result showed a significant difference (p

Mette Stagaard Janas - One of the best experts on this subject based on the ideXlab platform.

  • Lung hypoplasia – a possible Teratogenic Effect of valproate
    APMIS : acta pathologica microbiologica et immunologica Scandinavica, 1998
    Co-Authors: Mette Stagaard Janas, Mette Arrøe, Steen Holger Hansen, Niels Graem
    Abstract:

    Three cases of lung hypoplasia occurring in two siblings and in an unrelated child are reported. All three cases had been exposed to valproate in utero. The two female siblings had no other malformations, whereas the third female had a number of defects consistent with the fetal valproate syndrome. Thus, none of the known major causes of lung hypoplasia was present in any of the three cases. It is discussed whether pulmonary hypoplasia may be a separate disease entity, or caused by prenatal exposure to valproate.

  • lung hypoplasia a possible Teratogenic Effect of valproate
    Apmis, 1998
    Co-Authors: Mette Stagaard Janas, Mette Arrøe, Steen Holger Hansen, Niels Graem
    Abstract:

    Three cases of lung hypoplasia occurring in two siblings and in an unrelated child are reported. All three cases had been exposed to valproate in utero. The two female siblings had no other malformations, whereas the third female had a number of defects consistent with the fetal valproate syndrome. Thus, none of the known major causes of lung hypoplasia was present in any of the three cases. It is discussed whether pulmonary hypoplasia may be a separate disease entity, or caused by prenatal exposure to valproate.