The Experts below are selected from a list of 144294 Experts worldwide ranked by ideXlab platform
Liu Lei - One of the best experts on this subject based on the ideXlab platform.
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Sanguinaria canadensis: Traditional Medicine, phytochemical composition, biological activities and current issues
ePublications@SCU, 2016Co-Authors: Croaker Andrew, King, Graham J, Pyne, John H, Anoopkumar-dukie Shailendra, Liu LeiAbstract:Sanguinaria canadensis, also known as bloodroot, is a Traditional Medicine used by Native Americans to treat a diverse range of clinical conditions. The plants rhizome contains several alkaloids that individually target multiple molecular processes. These bioactive compounds, mechanistically correlate with the plant’s history of ethnobotanical use. Despite their identification over 50 years ago, the alkaloids of S. canadensis have not been developed into successful therapeutic agents. Instead, they have been associated with clinical toxicities ranging from mouthwash induced leukoplakia to cancer salve necrosis and treatment failure. This review explores the historical use of S. canadensis, the molecular actions of the benzophenanthridine and protopin alkaloids it contains, and explores natural alkaloid variation as a possible rationale for the inconsistent efficacy and toxicities encountered by S. canadensis therapies. Current veterinary and medicinal uses of the plant are studied with an assessment of obstacles to the pharmaceutical development of S. canadensis alkaloid based therapeutics
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Sanguinaria canadensis: Traditional Medicine, Phytochemical Composition, Biological Activities and Current Uses
MDPI, 2016Co-Authors: Croaker Andrew, King, Graham J, Pyne, John H, Anoopkumar-dukie Shailendra, Liu LeiAbstract:Sanguinaria canadensis, also known as bloodroot, is a Traditional Medicine used by Native Americans to treat a diverse range of clinical conditions. The plants rhizome contains several alkaloids that individually target multiple molecular processes. These bioactive compounds, mechanistically correlate with the plant’s history of ethnobotanical use. Despite their identification over 50 years ago, the alkaloids of S. canadensis have not been developed into successful therapeutic agents. Instead, they have been associated with clinical toxicities ranging from mouthwash induced leukoplakia to cancer salve necrosis and treatment failure. This review explores the historical use of S. canadensis, the molecular actions of the benzophenanthridine and protopin alkaloids it contains, and explores natural alkaloid variation as a possible rationale for the inconsistent efficacy and toxicities encountered by S. canadensis therapies. Current veterinary and medicinal uses of the plant are studied with an assessment of obstacles to the pharmaceutical development of S. canadensis alkaloid based therapeutics.Full Tex
Andrew Townesmith - One of the best experts on this subject based on the ideXlab platform.
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Herbal mixtures in Traditional Medicine in Northern Peru
Journal of Ethnobiology and Ethnomedicine, 2010Co-Authors: Rainer W Bussmann, Ashley Glenn, Karen Meyer, Alyse Kuhlman, Andrew TownesmithAbstract:The investigation of plant mixtures used in Traditional Medicine in Northern Peru yielded a total of 974 herbal preparations used to treat 164 different afflictions. Psychosomatic disorders were, with almost 30% of all recipes applied, the most important afflictions treated. In most cases, healers used only one or two mixtures to treat an illness. However, up to 49 different preparations were used to treat the same disease. This indicates a high degree of experimentation. Altogether 330 plant species, representing almost 65% of the medicinal flora used in the region were applied in mixtures. The overwhelming number of plant mixtures contained 2-7 different plant species, although in the most extreme case 27 distinct species were included. The cluster analysis confirmed that mixtures used for applications like inflammations, infections and blood purification, as well as cough, cold, bronchitis or other respiratory disorders, or urinary infection and kidney problems had similar floristic compositions. Mixtures used for nervous system disorders, anxiety and heart problems often had a similar composition
Croaker Andrew - One of the best experts on this subject based on the ideXlab platform.
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Sanguinaria canadensis: Traditional Medicine, phytochemical composition, biological activities and current issues
ePublications@SCU, 2016Co-Authors: Croaker Andrew, King, Graham J, Pyne, John H, Anoopkumar-dukie Shailendra, Liu LeiAbstract:Sanguinaria canadensis, also known as bloodroot, is a Traditional Medicine used by Native Americans to treat a diverse range of clinical conditions. The plants rhizome contains several alkaloids that individually target multiple molecular processes. These bioactive compounds, mechanistically correlate with the plant’s history of ethnobotanical use. Despite their identification over 50 years ago, the alkaloids of S. canadensis have not been developed into successful therapeutic agents. Instead, they have been associated with clinical toxicities ranging from mouthwash induced leukoplakia to cancer salve necrosis and treatment failure. This review explores the historical use of S. canadensis, the molecular actions of the benzophenanthridine and protopin alkaloids it contains, and explores natural alkaloid variation as a possible rationale for the inconsistent efficacy and toxicities encountered by S. canadensis therapies. Current veterinary and medicinal uses of the plant are studied with an assessment of obstacles to the pharmaceutical development of S. canadensis alkaloid based therapeutics
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Sanguinaria canadensis: Traditional Medicine, Phytochemical Composition, Biological Activities and Current Uses
MDPI, 2016Co-Authors: Croaker Andrew, King, Graham J, Pyne, John H, Anoopkumar-dukie Shailendra, Liu LeiAbstract:Sanguinaria canadensis, also known as bloodroot, is a Traditional Medicine used by Native Americans to treat a diverse range of clinical conditions. The plants rhizome contains several alkaloids that individually target multiple molecular processes. These bioactive compounds, mechanistically correlate with the plant’s history of ethnobotanical use. Despite their identification over 50 years ago, the alkaloids of S. canadensis have not been developed into successful therapeutic agents. Instead, they have been associated with clinical toxicities ranging from mouthwash induced leukoplakia to cancer salve necrosis and treatment failure. This review explores the historical use of S. canadensis, the molecular actions of the benzophenanthridine and protopin alkaloids it contains, and explores natural alkaloid variation as a possible rationale for the inconsistent efficacy and toxicities encountered by S. canadensis therapies. Current veterinary and medicinal uses of the plant are studied with an assessment of obstacles to the pharmaceutical development of S. canadensis alkaloid based therapeutics.Full Tex
Gabriele Volpato - One of the best experts on this subject based on the ideXlab platform.
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herbal mixtures in the Traditional Medicine of eastern cuba
Journal of Ethnopharmacology, 2004Co-Authors: Juan Hernandez Cano, Gabriele VolpatoAbstract:Herbal mixtures in the Traditional Medicine of Eastern Cuba. Traditional herbal mixtures in Eastern Cuba are investigated through interviews with 130 knowledgeable people and Traditional healers of the provinces of Santiago de Cuba and Guantanamo. One hundred seventy plant species and other products are used in 199 formulas, galones being the more complex. Cocos nucifera L. (Arecaceae), Bidens pilosa L. (Asteraceae), Cissus sicyoides L. (Vitaceae), Erythroxylum havanense Jacq. (Erythroxylaceae) and Stachytarpheta jamaicensis (L.) Vahl. (Verbenaceae) are the species most frequently cited. The ecological distribution of the taxa and cultural and anthropological aspects of mixtures are highlighted; particularly American and African influences that have shaped local knowledge about plant combinations are discussed.
Ester Speroni - One of the best experts on this subject based on the ideXlab platform.
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review on some plants of indian Traditional Medicine with antioxidant activity
Journal of Ethnopharmacology, 2000Co-Authors: Paolo Scartezzini, Ester SperoniAbstract:A lot of medicinal plants, Traditionally used for thousands of years, are present in a group of herbal preparations of the Indian Traditional health care system (Ayurveda) named Rasayana proposed for their interesting antioxidant activities. Among the medicinal plants used in ayurvedic Rasayana for their therapeutic action, some of these have been throughly investigated. In the present paper seven plants (Emblica officinalis L., Curcuma longa L., Mangifera indica L., Momordica charantia L., Santalum album L., Swertia chirata Buch-Ham, Withania somnifera (L.) Dunal) are viewed for their historical, etymological, morphological, phytochemical and pharmacological aspects. The plants described contain antioxidant principles, that can explain and justify their use in Traditional Medicine in the past as well as the present. In order to identify the plants with antioxidant activity in Ayurveda, a formulation of some rasayanas with well defined antioxidant properties has been examinated. For this purpose, we have considered Sharma's work on the preparation MAK4, MAK5, MA631, MA 471, MA Raja's Cup, MA Student Rasayana, MA Ladies Rasayana.
