The Experts below are selected from a list of 60 Experts worldwide ranked by ideXlab platform
Christian B. W. Stark - One of the best experts on this subject based on the ideXlab platform.
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Tetrapropylammonium Perruthenate catalyzed glycol cleavage to carboxylic di acids
ChemInform, 2012Co-Authors: Andrea-katharina C. Schmidt, Christian B. W. StarkAbstract:The reaction uses NMO as a sole oxidant and is applied to a wide range of diols leading to the carboxylic acids, bisacids and esters.
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Tetrapropylammonium Perruthenate Catalyzed Glycol Cleavage to Carboxylic (Di)Acids
Organic letters, 2011Co-Authors: Andrea-katharina C. Schmidt, Christian B. W. StarkAbstract:A new method to accomplish glycol cleavage to carboxylic (di)acids in one step using catalytic amounts of Tetrapropylammonium Perruthenate (TPAP) together with N-methylmorpholine N-Oxide (NMO) as the stoichiometric oxidant is presented. In addition to regenerating the active catalyst, the N-oxide stabilizes intermediary carbonyl hydrates and thereby shifts a crucial equilibrium. The mild oxidation protocol is applicable to a broad range of substrates providing the respective acids, diacids, or keto acids in high yields.
Andrea-katharina C. Schmidt - One of the best experts on this subject based on the ideXlab platform.
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Tetrapropylammonium Perruthenate catalyzed glycol cleavage to carboxylic di acids
ChemInform, 2012Co-Authors: Andrea-katharina C. Schmidt, Christian B. W. StarkAbstract:The reaction uses NMO as a sole oxidant and is applied to a wide range of diols leading to the carboxylic acids, bisacids and esters.
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Tetrapropylammonium Perruthenate Catalyzed Glycol Cleavage to Carboxylic (Di)Acids
Organic letters, 2011Co-Authors: Andrea-katharina C. Schmidt, Christian B. W. StarkAbstract:A new method to accomplish glycol cleavage to carboxylic (di)acids in one step using catalytic amounts of Tetrapropylammonium Perruthenate (TPAP) together with N-methylmorpholine N-Oxide (NMO) as the stoichiometric oxidant is presented. In addition to regenerating the active catalyst, the N-oxide stabilizes intermediary carbonyl hydrates and thereby shifts a crucial equilibrium. The mild oxidation protocol is applicable to a broad range of substrates providing the respective acids, diacids, or keto acids in high yields.
K. De Wael - One of the best experts on this subject based on the ideXlab platform.
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The electrochemistry of Tetrapropylammonium Perruthenate, its role in the oxidation of primary alcohols and its potential for electrochemical recycling
Electrochimica Acta, 2015Co-Authors: J. Lybaert, Bert U. W. Maes, K. Abbaspour Tehrani, K. De WaelAbstract:The search for strategies aiming at more sustainable (oxidation) reactions has led to the application of electrochemistry for recycling the spent catalyst. In this work, an electrochemical study of the Tetrapropylammonium Perruthenate catalyst (TPAP) and its activity towards a primary alcohol, n-butanol, has been carried out as well as a control study with tert-butanol. The redox chemistry of TPAP and the transition between the Perruthenate anion and ruthenium tetroxide in a non-aqueous solvent have been, for the first time, investigated in depth. The oxidation reaction of n-butanol in the presence of TPAP has been electrochemically elucidated by performing potentiostatic experiments and registration of the corresponding oxidation current. Furthermore, it was shown that, by applying a specific potential, the reoxidized TPAP is able to oxidize/convert the primary alcohol, paving the way for practical applications using TPAP in electrochemical synthesis. The conversion of n-butanol into n-butanal was proven by the use of GC-MS.
Erli Sugiono - One of the best experts on this subject based on the ideXlab platform.
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unifying metal and organocatalysis for asymmetric oxidative iminium activation a relay catalytic system enabling the combined allylic oxidation of alcohols and prolinol ether catalyzed iminium reactions
Chemistry: A European Journal, 2012Co-Authors: Magnus Rueping, Henrik Sunden, Erli SugionoAbstract:A multicatalytic system consisting of Tetrapropylammonium Perruthenate/N-methylmorpholine N-oxide (TPAP/NMO) as oxidant, and diarylprolinol TMS-ether as chiral amine catalyst, has been developed and applied in the efficient construction of valuable chiral molecules. The one-pot domino reactions elaborated in the present study are based on the in situ generation of α,β-unsaturated aldehydes from allylic alcohols and their subsequent use in various asymmetric transformations (e.g., cyclopropanation, Michael addition, Michael addition/acetalization). TPAP as a substrate-selective redox catalyst is well tolerated by the amine catalyst and the domino reactions proceed in good yields and high enantioselectivities. The compatibility of metal and organocatalysis presented herein widens the scope of asymmetric iminium catalysis.
Stephen P Marsden - One of the best experts on this subject based on the ideXlab platform.
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Tetrapropylammonium Perruthenate pr4n ruo4 tpap a catalytic oxidant for organic synthesis
Synthesis, 1994Co-Authors: Steven V Ley, Joanne Norman, William P Griffith, Stephen P MarsdenAbstract:This article reviews the oxidations of a wide range of molecules with Tetrapropylammonium Perruthenate including examples of both double oxidations and selective oxidations. Mechanistic studies are discussed and general experimental procedures are reported. In addition several interesting developments in the chemistry of this reagent are outlined, that is, heteroatom oxidation, cleavage reactions and also its use in sequential reaction processes. In order to present a complete picture examples of failed reactions have been included