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Raymond P. White - One of the best experts on this subject based on the ideXlab platform.
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Monitoring for Periodontal Inflammatory Disease in the Third Molar Region
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2014Co-Authors: Brent A. Golden, Ceib Phillips, Steven Offenbacher, Carrie Baldwin, Colin Sherwood, Omar Abdelbaky, Raymond P. WhiteAbstract:Purpose To assess changes at 2-year intervals in the periodontal status of the Third Molar region in participants enrolled with asymptomatic Third Molars and no clinical evidence of Third Molar region periodontal pathology. Participants and Methods The included participants who presented with a healthy periodontal status (all probing depths [PDs], Results One hundred twenty-nine participants had a Third Molar region PD shallower than 4 mm at enrollment. Most participants were Caucasian (85%), women (60%), younger than 25 years (62%), educated beyond high school (84%), and with good oral health habits. At 6 years, excluding the 61 participants lost to follow-up, 47% participants had had Third Molars removed, 21% had developed at least 1 PD of at least 4 mm in the Third Molar region since enrollment, and 32% retained the periodontal status at enrollment (all PDs in Third Molar region, Conclusions Although not all participants could be followed for 6 years after enrollment or chose to retain Third Molars, one Third of participants maintained the Third Molar region periodontal status assessed at baseline for 6 years after enrollment; no clinical evidence of pathology developed over time.
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risk markers for periodontal pathology over time in the Third Molar and non Third Molar regions in young adults
Journal of Oral and Maxillofacial Surgery, 2008Co-Authors: Raymond P. White, Ceib Phillips, Donald J. Hull, Steven Offenbacher, George H. Blakey, Richard H. HaugAbstract:Purpose This study was conducted to analyze the clinical impact of risk markers for Third Molar and non–Third Molar periodontal pathology over time. Patients and Methods Data were obtained from healthy adults with 4 asymptomatic Third Molars in an institutional review board–approved trial. Full-mouth periodontal probing depth (PD) data were collected as clinical measures of possible periodontal pathology. The Third Molar region included the 6 Third Molar probing sites and the 2 second Molar distal probing sites (maximum of 16 sites per jaw). The non–Third Molar region included all remaining probing sites (maximum of 80 sites per jaw). Periodontal PDs were considered indicator variables for clinically detected periodontal pathology or its absence at baseline and follow-up. Subjects were grouped based on all PD less than 4 mm (no disease), 1 to 3 PD ≥4 mm (incipient disease), or at least 4 PD ≥4 mm (early disease). Levels of periodontal pathogens and gingival crevicular fluid inflammatory mediators at baseline also were assayed as risk markers for periodontal pathology. Baseline risk markers and possible confounding variables were included in risk assessment models to derive odds ratios and 95% confidence intervals for periodontal pathology in the Third Molar and non–Third Molar regions at follow-up. Results A total of 195 subjects had a median follow-up of 5.9 years (interquartile range [IQR] = 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQR = 22 to 34 years); 52% were female, 84% were Caucasian, and 10% were African-American. A significant association was found between baseline and follow-up Third Molar region and non–Third Molar region periodontal pathology indicators ( P Conclusions In young adults, the presence of periodontal pathology as indicated by periodontal PDs in the Third Molar region at baseline was predictive of detection of periodontal pathology in the Third Molar and non–Third Molar regions at follow-up.
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Risk Markers for Periodontal Pathology Over Time in the Third Molar and Non–Third Molar Regions in Young Adults
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008Co-Authors: Raymond P. White, Ceib Phillips, Donald J. Hull, Steven Offenbacher, George H. Blakey, Richard H. HaugAbstract:Purpose This study was conducted to analyze the clinical impact of risk markers for Third Molar and non–Third Molar periodontal pathology over time. Patients and Methods Data were obtained from healthy adults with 4 asymptomatic Third Molars in an institutional review board–approved trial. Full-mouth periodontal probing depth (PD) data were collected as clinical measures of possible periodontal pathology. The Third Molar region included the 6 Third Molar probing sites and the 2 second Molar distal probing sites (maximum of 16 sites per jaw). The non–Third Molar region included all remaining probing sites (maximum of 80 sites per jaw). Periodontal PDs were considered indicator variables for clinically detected periodontal pathology or its absence at baseline and follow-up. Subjects were grouped based on all PD less than 4 mm (no disease), 1 to 3 PD ≥4 mm (incipient disease), or at least 4 PD ≥4 mm (early disease). Levels of periodontal pathogens and gingival crevicular fluid inflammatory mediators at baseline also were assayed as risk markers for periodontal pathology. Baseline risk markers and possible confounding variables were included in risk assessment models to derive odds ratios and 95% confidence intervals for periodontal pathology in the Third Molar and non–Third Molar regions at follow-up. Results A total of 195 subjects had a median follow-up of 5.9 years (interquartile range [IQR] = 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQR = 22 to 34 years); 52% were female, 84% were Caucasian, and 10% were African-American. A significant association was found between baseline and follow-up Third Molar region and non–Third Molar region periodontal pathology indicators ( P Conclusions In young adults, the presence of periodontal pathology as indicated by periodontal PDs in the Third Molar region at baseline was predictive of detection of periodontal pathology in the Third Molar and non–Third Molar regions at follow-up.
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Third Molar root development and recovery from Third Molar surgery.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2007Co-Authors: Haeman Noori, David L. Hill, Daniel A. Shugars, Ceib Phillips, Raymond P. WhiteAbstract:Purpose This study was conducted to determine if the completeness of the root formation of mandibular Third Molars prior to removal affected clinical and health-related quality of life (HRQOL) recovery. Patients and Methods Data from HRQOL responses from patients and clinical outcome data were available after Third Molar surgery conducted by surgeons in community practice and academic centers. The root development of each mandibular Third Molar on presurgery panoramic radiographs for these patients was assessed by trained clinician observers. Patients were categorized as those with complete root formation (both mandibular Third Molars had 100% completely formed roots) or as those with incomplete root formation (at least 1 mandibular Third Molar not completely formed). The proportion of patients who experienced delayed clinical or HRQOL recovery that exceeded a clinically relevant criterion value were compared for these 2 groups of patients using χ2 statistics. Level of significance was set at 0.05. Results Both mandibular Third Molars had 100% completely formed roots in 118 patients; at least 1 mandibular Third Molar was not completely formed in 218 patients. If patients had a mandibular Third Molar with roots less than 100% complete, they more likely: were female (65% vs 58%), were less than 25 years old (95% vs 54%), P Conclusions Incomplete lower Third Molar root formation presurgery may not be a predictor of better or worse clinical or HRQOL recovery after surgery. Other clinical, demographic, and health indicators should influence surgeons’ recommendations and patients’ decisions regarding Third Molar treatment including surgery.
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changes in Third Molar and nonThird Molar periodontal pathology over time
Journal of Oral and Maxillofacial Surgery, 2006Co-Authors: George H. Blakey, Ceib Phillips, Donald J. Hull, Steven Offenbacher, Richard H. Haug, Raymond P. WhiteAbstract:Purpose The purpose of this study was to assess changes in periodontal probing depth (PD) over time for Third Molar and nonThird Molar regions in young adults. Patients and Methods The data were obtained from healthy subjects with 4 asymptomatic Third Molars, enrolled in an IRB-approved longitudinal trial. Demographic and oral health data were collected at baseline. Full-mouth PD, 6 sites per tooth, was conducted to determine periodontal status at baseline and at longest follow-up. The Third Molar region was defined as the PD for 6 sites around the Third Molars and the 2 sites on the distal of the second Molars. The nonThird Molar region was defined as the remainder of the PD sites in the mouth. The primary outcome measures for this study were the occurrence of a PD greater than or equal to 4 mm and the increase in PD of at least 2 mm in the Third Molar and nonThird Molar regions. Changes from enrollment to longest follow-up were compared by the binomial or McNemar’s test. Level of significance was .05. Results Data from 195 subjects were available, and the median follow-up was 5.9 years (interquartile range [IQ], 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQ, 22.0 to 34.0 years); 52% were female, 84% were Caucasian, and 10% were African American. The proportion of subjects with at least 1 involved site in nonThird Molars increased significantly from baseline to follow-up, 36% to 49% ( P P P = .05), also reflecting mostly changes in mandibular nonThird Molars, 44% to 59% ( P = .05). Conclusion In this unique longitudinal clinical study of early periodontal disease in young adults, periodontal pathology worsened over time for nonThird Molars. This was more likely if PD greater than or equal to 4 mm was detected in the Third Molar region.
Candan Semra Paksoy - One of the best experts on this subject based on the ideXlab platform.
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radiographic evaluation of Third Molar development in relation to chronological age among turkish children and youth
Forensic Science International, 2007Co-Authors: Kaan Orhan, Levent Ozer, Ayse Isil Orhan, Sand Dogan, Candan Semra PaksoyAbstract:A sharp increase in forensic age estimation of living persons has been observed in recent years. However, ethnic populations residing in different countries have been insufficiently analyzed. According to 2004 data compiled by the Essen-based Turkey Research Center, there are 3.8 million Turkish people living abroad, and 3.2 million of them reside in European Union countries. Despite the high number of Turks living abroad, little is known about Third-Molar development for forensic application in this population. Hence, it was considered worthwhile to determine the developmental stages of the Third Molar in a group of Turkish population, to assess chronological age estimation based on the developmental stages, and to compare Third Molar development according to sex, age and location. Orthopantomograms of 1134 Turkish patients, ages 4-20 years were examined and Third-Molar developmental stages were evaluated based on Demirjian's classifications. Orthopantomograms were scored by two different observers, and Wilcoxon matched-pairs signed-ranks test used to test intra- and inter-observer reliability revealed a strong agreement between both intra- and inter-observer measurements. Linear regression analysis was performed to correlate Third-Molar development and chronological age, and further statistical analysis was performed to determine the relation between sex, age and location. Results showed a strong linear correlation between age and Molar development (males: r(2)=0.57; females: r(2)=0.56). Mineralizations of left and right Third Molars were compared using Wilcoxon tests, and no statistical differences were found. No significant differences were found in Third-Molar development between males and females. Mandibular Third Molar crypt formation was observed in 2.4% of patients at age seven and maxillary Third Molar crypt formation was observed in 1.3% of patients at age seven. A strong correlation was found between Third-Molar development and chronological age. Among the Turkish population, Third Molar crypt formation is observable at as early as 7 years in both the mandible and maxilla. Agenesis can be determined conclusively if no radiolucent bud is present by age 14.
Richard H. Haug - One of the best experts on this subject based on the ideXlab platform.
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risk markers for periodontal pathology over time in the Third Molar and non Third Molar regions in young adults
Journal of Oral and Maxillofacial Surgery, 2008Co-Authors: Raymond P. White, Ceib Phillips, Donald J. Hull, Steven Offenbacher, George H. Blakey, Richard H. HaugAbstract:Purpose This study was conducted to analyze the clinical impact of risk markers for Third Molar and non–Third Molar periodontal pathology over time. Patients and Methods Data were obtained from healthy adults with 4 asymptomatic Third Molars in an institutional review board–approved trial. Full-mouth periodontal probing depth (PD) data were collected as clinical measures of possible periodontal pathology. The Third Molar region included the 6 Third Molar probing sites and the 2 second Molar distal probing sites (maximum of 16 sites per jaw). The non–Third Molar region included all remaining probing sites (maximum of 80 sites per jaw). Periodontal PDs were considered indicator variables for clinically detected periodontal pathology or its absence at baseline and follow-up. Subjects were grouped based on all PD less than 4 mm (no disease), 1 to 3 PD ≥4 mm (incipient disease), or at least 4 PD ≥4 mm (early disease). Levels of periodontal pathogens and gingival crevicular fluid inflammatory mediators at baseline also were assayed as risk markers for periodontal pathology. Baseline risk markers and possible confounding variables were included in risk assessment models to derive odds ratios and 95% confidence intervals for periodontal pathology in the Third Molar and non–Third Molar regions at follow-up. Results A total of 195 subjects had a median follow-up of 5.9 years (interquartile range [IQR] = 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQR = 22 to 34 years); 52% were female, 84% were Caucasian, and 10% were African-American. A significant association was found between baseline and follow-up Third Molar region and non–Third Molar region periodontal pathology indicators ( P Conclusions In young adults, the presence of periodontal pathology as indicated by periodontal PDs in the Third Molar region at baseline was predictive of detection of periodontal pathology in the Third Molar and non–Third Molar regions at follow-up.
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Risk Markers for Periodontal Pathology Over Time in the Third Molar and Non–Third Molar Regions in Young Adults
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008Co-Authors: Raymond P. White, Ceib Phillips, Donald J. Hull, Steven Offenbacher, George H. Blakey, Richard H. HaugAbstract:Purpose This study was conducted to analyze the clinical impact of risk markers for Third Molar and non–Third Molar periodontal pathology over time. Patients and Methods Data were obtained from healthy adults with 4 asymptomatic Third Molars in an institutional review board–approved trial. Full-mouth periodontal probing depth (PD) data were collected as clinical measures of possible periodontal pathology. The Third Molar region included the 6 Third Molar probing sites and the 2 second Molar distal probing sites (maximum of 16 sites per jaw). The non–Third Molar region included all remaining probing sites (maximum of 80 sites per jaw). Periodontal PDs were considered indicator variables for clinically detected periodontal pathology or its absence at baseline and follow-up. Subjects were grouped based on all PD less than 4 mm (no disease), 1 to 3 PD ≥4 mm (incipient disease), or at least 4 PD ≥4 mm (early disease). Levels of periodontal pathogens and gingival crevicular fluid inflammatory mediators at baseline also were assayed as risk markers for periodontal pathology. Baseline risk markers and possible confounding variables were included in risk assessment models to derive odds ratios and 95% confidence intervals for periodontal pathology in the Third Molar and non–Third Molar regions at follow-up. Results A total of 195 subjects had a median follow-up of 5.9 years (interquartile range [IQR] = 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQR = 22 to 34 years); 52% were female, 84% were Caucasian, and 10% were African-American. A significant association was found between baseline and follow-up Third Molar region and non–Third Molar region periodontal pathology indicators ( P Conclusions In young adults, the presence of periodontal pathology as indicated by periodontal PDs in the Third Molar region at baseline was predictive of detection of periodontal pathology in the Third Molar and non–Third Molar regions at follow-up.
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changes in Third Molar and nonThird Molar periodontal pathology over time
Journal of Oral and Maxillofacial Surgery, 2006Co-Authors: George H. Blakey, Ceib Phillips, Donald J. Hull, Steven Offenbacher, Richard H. Haug, Raymond P. WhiteAbstract:Purpose The purpose of this study was to assess changes in periodontal probing depth (PD) over time for Third Molar and nonThird Molar regions in young adults. Patients and Methods The data were obtained from healthy subjects with 4 asymptomatic Third Molars, enrolled in an IRB-approved longitudinal trial. Demographic and oral health data were collected at baseline. Full-mouth PD, 6 sites per tooth, was conducted to determine periodontal status at baseline and at longest follow-up. The Third Molar region was defined as the PD for 6 sites around the Third Molars and the 2 sites on the distal of the second Molars. The nonThird Molar region was defined as the remainder of the PD sites in the mouth. The primary outcome measures for this study were the occurrence of a PD greater than or equal to 4 mm and the increase in PD of at least 2 mm in the Third Molar and nonThird Molar regions. Changes from enrollment to longest follow-up were compared by the binomial or McNemar’s test. Level of significance was .05. Results Data from 195 subjects were available, and the median follow-up was 5.9 years (interquartile range [IQ], 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQ, 22.0 to 34.0 years); 52% were female, 84% were Caucasian, and 10% were African American. The proportion of subjects with at least 1 involved site in nonThird Molars increased significantly from baseline to follow-up, 36% to 49% ( P P P = .05), also reflecting mostly changes in mandibular nonThird Molars, 44% to 59% ( P = .05). Conclusion In this unique longitudinal clinical study of early periodontal disease in young adults, periodontal pathology worsened over time for nonThird Molars. This was more likely if PD greater than or equal to 4 mm was detected in the Third Molar region.
Ceib Phillips - One of the best experts on this subject based on the ideXlab platform.
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Monitoring for Periodontal Inflammatory Disease in the Third Molar Region
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2014Co-Authors: Brent A. Golden, Ceib Phillips, Steven Offenbacher, Carrie Baldwin, Colin Sherwood, Omar Abdelbaky, Raymond P. WhiteAbstract:Purpose To assess changes at 2-year intervals in the periodontal status of the Third Molar region in participants enrolled with asymptomatic Third Molars and no clinical evidence of Third Molar region periodontal pathology. Participants and Methods The included participants who presented with a healthy periodontal status (all probing depths [PDs], Results One hundred twenty-nine participants had a Third Molar region PD shallower than 4 mm at enrollment. Most participants were Caucasian (85%), women (60%), younger than 25 years (62%), educated beyond high school (84%), and with good oral health habits. At 6 years, excluding the 61 participants lost to follow-up, 47% participants had had Third Molars removed, 21% had developed at least 1 PD of at least 4 mm in the Third Molar region since enrollment, and 32% retained the periodontal status at enrollment (all PDs in Third Molar region, Conclusions Although not all participants could be followed for 6 years after enrollment or chose to retain Third Molars, one Third of participants maintained the Third Molar region periodontal status assessed at baseline for 6 years after enrollment; no clinical evidence of pathology developed over time.
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risk markers for periodontal pathology over time in the Third Molar and non Third Molar regions in young adults
Journal of Oral and Maxillofacial Surgery, 2008Co-Authors: Raymond P. White, Ceib Phillips, Donald J. Hull, Steven Offenbacher, George H. Blakey, Richard H. HaugAbstract:Purpose This study was conducted to analyze the clinical impact of risk markers for Third Molar and non–Third Molar periodontal pathology over time. Patients and Methods Data were obtained from healthy adults with 4 asymptomatic Third Molars in an institutional review board–approved trial. Full-mouth periodontal probing depth (PD) data were collected as clinical measures of possible periodontal pathology. The Third Molar region included the 6 Third Molar probing sites and the 2 second Molar distal probing sites (maximum of 16 sites per jaw). The non–Third Molar region included all remaining probing sites (maximum of 80 sites per jaw). Periodontal PDs were considered indicator variables for clinically detected periodontal pathology or its absence at baseline and follow-up. Subjects were grouped based on all PD less than 4 mm (no disease), 1 to 3 PD ≥4 mm (incipient disease), or at least 4 PD ≥4 mm (early disease). Levels of periodontal pathogens and gingival crevicular fluid inflammatory mediators at baseline also were assayed as risk markers for periodontal pathology. Baseline risk markers and possible confounding variables were included in risk assessment models to derive odds ratios and 95% confidence intervals for periodontal pathology in the Third Molar and non–Third Molar regions at follow-up. Results A total of 195 subjects had a median follow-up of 5.9 years (interquartile range [IQR] = 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQR = 22 to 34 years); 52% were female, 84% were Caucasian, and 10% were African-American. A significant association was found between baseline and follow-up Third Molar region and non–Third Molar region periodontal pathology indicators ( P Conclusions In young adults, the presence of periodontal pathology as indicated by periodontal PDs in the Third Molar region at baseline was predictive of detection of periodontal pathology in the Third Molar and non–Third Molar regions at follow-up.
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Risk Markers for Periodontal Pathology Over Time in the Third Molar and Non–Third Molar Regions in Young Adults
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008Co-Authors: Raymond P. White, Ceib Phillips, Donald J. Hull, Steven Offenbacher, George H. Blakey, Richard H. HaugAbstract:Purpose This study was conducted to analyze the clinical impact of risk markers for Third Molar and non–Third Molar periodontal pathology over time. Patients and Methods Data were obtained from healthy adults with 4 asymptomatic Third Molars in an institutional review board–approved trial. Full-mouth periodontal probing depth (PD) data were collected as clinical measures of possible periodontal pathology. The Third Molar region included the 6 Third Molar probing sites and the 2 second Molar distal probing sites (maximum of 16 sites per jaw). The non–Third Molar region included all remaining probing sites (maximum of 80 sites per jaw). Periodontal PDs were considered indicator variables for clinically detected periodontal pathology or its absence at baseline and follow-up. Subjects were grouped based on all PD less than 4 mm (no disease), 1 to 3 PD ≥4 mm (incipient disease), or at least 4 PD ≥4 mm (early disease). Levels of periodontal pathogens and gingival crevicular fluid inflammatory mediators at baseline also were assayed as risk markers for periodontal pathology. Baseline risk markers and possible confounding variables were included in risk assessment models to derive odds ratios and 95% confidence intervals for periodontal pathology in the Third Molar and non–Third Molar regions at follow-up. Results A total of 195 subjects had a median follow-up of 5.9 years (interquartile range [IQR] = 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQR = 22 to 34 years); 52% were female, 84% were Caucasian, and 10% were African-American. A significant association was found between baseline and follow-up Third Molar region and non–Third Molar region periodontal pathology indicators ( P Conclusions In young adults, the presence of periodontal pathology as indicated by periodontal PDs in the Third Molar region at baseline was predictive of detection of periodontal pathology in the Third Molar and non–Third Molar regions at follow-up.
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Third Molar root development and recovery from Third Molar surgery.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2007Co-Authors: Haeman Noori, David L. Hill, Daniel A. Shugars, Ceib Phillips, Raymond P. WhiteAbstract:Purpose This study was conducted to determine if the completeness of the root formation of mandibular Third Molars prior to removal affected clinical and health-related quality of life (HRQOL) recovery. Patients and Methods Data from HRQOL responses from patients and clinical outcome data were available after Third Molar surgery conducted by surgeons in community practice and academic centers. The root development of each mandibular Third Molar on presurgery panoramic radiographs for these patients was assessed by trained clinician observers. Patients were categorized as those with complete root formation (both mandibular Third Molars had 100% completely formed roots) or as those with incomplete root formation (at least 1 mandibular Third Molar not completely formed). The proportion of patients who experienced delayed clinical or HRQOL recovery that exceeded a clinically relevant criterion value were compared for these 2 groups of patients using χ2 statistics. Level of significance was set at 0.05. Results Both mandibular Third Molars had 100% completely formed roots in 118 patients; at least 1 mandibular Third Molar was not completely formed in 218 patients. If patients had a mandibular Third Molar with roots less than 100% complete, they more likely: were female (65% vs 58%), were less than 25 years old (95% vs 54%), P Conclusions Incomplete lower Third Molar root formation presurgery may not be a predictor of better or worse clinical or HRQOL recovery after surgery. Other clinical, demographic, and health indicators should influence surgeons’ recommendations and patients’ decisions regarding Third Molar treatment including surgery.
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changes in Third Molar and nonThird Molar periodontal pathology over time
Journal of Oral and Maxillofacial Surgery, 2006Co-Authors: George H. Blakey, Ceib Phillips, Donald J. Hull, Steven Offenbacher, Richard H. Haug, Raymond P. WhiteAbstract:Purpose The purpose of this study was to assess changes in periodontal probing depth (PD) over time for Third Molar and nonThird Molar regions in young adults. Patients and Methods The data were obtained from healthy subjects with 4 asymptomatic Third Molars, enrolled in an IRB-approved longitudinal trial. Demographic and oral health data were collected at baseline. Full-mouth PD, 6 sites per tooth, was conducted to determine periodontal status at baseline and at longest follow-up. The Third Molar region was defined as the PD for 6 sites around the Third Molars and the 2 sites on the distal of the second Molars. The nonThird Molar region was defined as the remainder of the PD sites in the mouth. The primary outcome measures for this study were the occurrence of a PD greater than or equal to 4 mm and the increase in PD of at least 2 mm in the Third Molar and nonThird Molar regions. Changes from enrollment to longest follow-up were compared by the binomial or McNemar’s test. Level of significance was .05. Results Data from 195 subjects were available, and the median follow-up was 5.9 years (interquartile range [IQ], 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQ, 22.0 to 34.0 years); 52% were female, 84% were Caucasian, and 10% were African American. The proportion of subjects with at least 1 involved site in nonThird Molars increased significantly from baseline to follow-up, 36% to 49% ( P P P = .05), also reflecting mostly changes in mandibular nonThird Molars, 44% to 59% ( P = .05). Conclusion In this unique longitudinal clinical study of early periodontal disease in young adults, periodontal pathology worsened over time for nonThird Molars. This was more likely if PD greater than or equal to 4 mm was detected in the Third Molar region.
Steven Offenbacher - One of the best experts on this subject based on the ideXlab platform.
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Monitoring for Periodontal Inflammatory Disease in the Third Molar Region
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2014Co-Authors: Brent A. Golden, Ceib Phillips, Steven Offenbacher, Carrie Baldwin, Colin Sherwood, Omar Abdelbaky, Raymond P. WhiteAbstract:Purpose To assess changes at 2-year intervals in the periodontal status of the Third Molar region in participants enrolled with asymptomatic Third Molars and no clinical evidence of Third Molar region periodontal pathology. Participants and Methods The included participants who presented with a healthy periodontal status (all probing depths [PDs], Results One hundred twenty-nine participants had a Third Molar region PD shallower than 4 mm at enrollment. Most participants were Caucasian (85%), women (60%), younger than 25 years (62%), educated beyond high school (84%), and with good oral health habits. At 6 years, excluding the 61 participants lost to follow-up, 47% participants had had Third Molars removed, 21% had developed at least 1 PD of at least 4 mm in the Third Molar region since enrollment, and 32% retained the periodontal status at enrollment (all PDs in Third Molar region, Conclusions Although not all participants could be followed for 6 years after enrollment or chose to retain Third Molars, one Third of participants maintained the Third Molar region periodontal status assessed at baseline for 6 years after enrollment; no clinical evidence of pathology developed over time.
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risk markers for periodontal pathology over time in the Third Molar and non Third Molar regions in young adults
Journal of Oral and Maxillofacial Surgery, 2008Co-Authors: Raymond P. White, Ceib Phillips, Donald J. Hull, Steven Offenbacher, George H. Blakey, Richard H. HaugAbstract:Purpose This study was conducted to analyze the clinical impact of risk markers for Third Molar and non–Third Molar periodontal pathology over time. Patients and Methods Data were obtained from healthy adults with 4 asymptomatic Third Molars in an institutional review board–approved trial. Full-mouth periodontal probing depth (PD) data were collected as clinical measures of possible periodontal pathology. The Third Molar region included the 6 Third Molar probing sites and the 2 second Molar distal probing sites (maximum of 16 sites per jaw). The non–Third Molar region included all remaining probing sites (maximum of 80 sites per jaw). Periodontal PDs were considered indicator variables for clinically detected periodontal pathology or its absence at baseline and follow-up. Subjects were grouped based on all PD less than 4 mm (no disease), 1 to 3 PD ≥4 mm (incipient disease), or at least 4 PD ≥4 mm (early disease). Levels of periodontal pathogens and gingival crevicular fluid inflammatory mediators at baseline also were assayed as risk markers for periodontal pathology. Baseline risk markers and possible confounding variables were included in risk assessment models to derive odds ratios and 95% confidence intervals for periodontal pathology in the Third Molar and non–Third Molar regions at follow-up. Results A total of 195 subjects had a median follow-up of 5.9 years (interquartile range [IQR] = 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQR = 22 to 34 years); 52% were female, 84% were Caucasian, and 10% were African-American. A significant association was found between baseline and follow-up Third Molar region and non–Third Molar region periodontal pathology indicators ( P Conclusions In young adults, the presence of periodontal pathology as indicated by periodontal PDs in the Third Molar region at baseline was predictive of detection of periodontal pathology in the Third Molar and non–Third Molar regions at follow-up.
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Risk Markers for Periodontal Pathology Over Time in the Third Molar and Non–Third Molar Regions in Young Adults
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008Co-Authors: Raymond P. White, Ceib Phillips, Donald J. Hull, Steven Offenbacher, George H. Blakey, Richard H. HaugAbstract:Purpose This study was conducted to analyze the clinical impact of risk markers for Third Molar and non–Third Molar periodontal pathology over time. Patients and Methods Data were obtained from healthy adults with 4 asymptomatic Third Molars in an institutional review board–approved trial. Full-mouth periodontal probing depth (PD) data were collected as clinical measures of possible periodontal pathology. The Third Molar region included the 6 Third Molar probing sites and the 2 second Molar distal probing sites (maximum of 16 sites per jaw). The non–Third Molar region included all remaining probing sites (maximum of 80 sites per jaw). Periodontal PDs were considered indicator variables for clinically detected periodontal pathology or its absence at baseline and follow-up. Subjects were grouped based on all PD less than 4 mm (no disease), 1 to 3 PD ≥4 mm (incipient disease), or at least 4 PD ≥4 mm (early disease). Levels of periodontal pathogens and gingival crevicular fluid inflammatory mediators at baseline also were assayed as risk markers for periodontal pathology. Baseline risk markers and possible confounding variables were included in risk assessment models to derive odds ratios and 95% confidence intervals for periodontal pathology in the Third Molar and non–Third Molar regions at follow-up. Results A total of 195 subjects had a median follow-up of 5.9 years (interquartile range [IQR] = 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQR = 22 to 34 years); 52% were female, 84% were Caucasian, and 10% were African-American. A significant association was found between baseline and follow-up Third Molar region and non–Third Molar region periodontal pathology indicators ( P Conclusions In young adults, the presence of periodontal pathology as indicated by periodontal PDs in the Third Molar region at baseline was predictive of detection of periodontal pathology in the Third Molar and non–Third Molar regions at follow-up.
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changes in Third Molar and nonThird Molar periodontal pathology over time
Journal of Oral and Maxillofacial Surgery, 2006Co-Authors: George H. Blakey, Ceib Phillips, Donald J. Hull, Steven Offenbacher, Richard H. Haug, Raymond P. WhiteAbstract:Purpose The purpose of this study was to assess changes in periodontal probing depth (PD) over time for Third Molar and nonThird Molar regions in young adults. Patients and Methods The data were obtained from healthy subjects with 4 asymptomatic Third Molars, enrolled in an IRB-approved longitudinal trial. Demographic and oral health data were collected at baseline. Full-mouth PD, 6 sites per tooth, was conducted to determine periodontal status at baseline and at longest follow-up. The Third Molar region was defined as the PD for 6 sites around the Third Molars and the 2 sites on the distal of the second Molars. The nonThird Molar region was defined as the remainder of the PD sites in the mouth. The primary outcome measures for this study were the occurrence of a PD greater than or equal to 4 mm and the increase in PD of at least 2 mm in the Third Molar and nonThird Molar regions. Changes from enrollment to longest follow-up were compared by the binomial or McNemar’s test. Level of significance was .05. Results Data from 195 subjects were available, and the median follow-up was 5.9 years (interquartile range [IQ], 4.6 to 6.9 years). Median age at enrollment was 26.2 years (IQ, 22.0 to 34.0 years); 52% were female, 84% were Caucasian, and 10% were African American. The proportion of subjects with at least 1 involved site in nonThird Molars increased significantly from baseline to follow-up, 36% to 49% ( P P P = .05), also reflecting mostly changes in mandibular nonThird Molars, 44% to 59% ( P = .05). Conclusion In this unique longitudinal clinical study of early periodontal disease in young adults, periodontal pathology worsened over time for nonThird Molars. This was more likely if PD greater than or equal to 4 mm was detected in the Third Molar region.
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Reliability of Third Molar probing measures and the systemic impact of Third Molar periodontal pathology.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2006Co-Authors: Kevin Moss, Raymond P. White, Steven Offenbacher, Sally M. Mauriello, Andrew T. Ruvo, James D. BeckAbstract:Purpose This study examined the reliability of assessing clinical periodontal measures on Third Molars, and the association between oral inflammation with periodontal pathology including Third Molars, and systemic inflammation including negative obstetric outcomes. Patients and Methods Reliability of Third Molar probing depth (PD) was assessed for 41 patients by trained examiners. The data for the association between oral inflammation with periodontal pathology and systemic outcomes were derived from an IRB-approved study, “Oral Conditions and Pregnancy.” Full mouth periodontal exams including Third Molars were conducted at less than 24 weeks of pregnancy. Periodontal status, moderate/severe periodontal disease (15 or more sites PD ≥4 mm) was considered as a possible predictor of systemic inflammation and pre-term birth. The upper quartile of the extent of PD for Third Molars alone (PD ≥4 mm) also was considered as a possible exposure variable for the same outcomes. Chi-square and t tests were used to determine statistical significance (0.05). Significant predictor variables were included in multivariate models. Unconditional logistic multivariate models were used to derive odds ratios (OR) and 95% confidence intervals (CI). Results Reliability of PD within 1 mm was excellent, and similar for Third Molars and non-Third Molars. Data from 1,020 obstetric patients were available for analysis. Eighteen percent of the patients delivered preterm, at less than 37 weeks. Having moderate/severe periodontal disease excluding Third Molars, was significantly associated with preterm birth ( P = .008). Results were more significant if Third Molars were included ( P = .0005). With multivariate models moderate/severe periodontal disease at enrollment including Third Molar PD, was associated with preterm birth (OR, 1.7; 95% CI, 1.1, 2.6). If only the extent of Third Molar PD was considered, odds also were increased for preterm birth (OR, 2.4; 95% CI, 1.1, 5.2). If only the extent of Third Molar PD was considered at enrollment, odds were increased for serum markers of systemic inflammation, elevated serum CRP, and oxidative stress, 8-isoPGF 2α . Conclusions Dental examiners could reliably assess clinical periodontal measures on Third Molars. Third Molars should be included in studies of systemic outcomes associated with oral inflammation. Women of child-bearing age should be made aware of the systemic risks of oral inflammation with Third Molar periodontal pathology.
