The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform
Ning Yan - One of the best experts on this subject based on the ideXlab platform.
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Application of Western red cedar (Thuja plicata) tree bark as a functional filler in pMDI wood adhesives
Industrial Crops and Products, 2018Co-Authors: Heyu Chen, Ning YanAbstract:Abstract In this study, Western red cedar (Thuja plicata) tree bark was used as a reactive functional filler (oven-dry particles,
Claudia Quezada - One of the best experts on this subject based on the ideXlab platform.
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Pro-apoptotic and anti-angiogenic properties of the α /β-thujone fraction from Thuja occidentalis on glioblastoma cells
Journal of Neuro-Oncology, 2016Co-Authors: Angelo Torres, Yosselyn Vargas, Cristian Carrasco, Cristian Torres, René Rocha, Rody San Martín, Ciro Oyarzún, Daniel Uribe, Claudia QuezadaAbstract:The most aggressive type of brain tumor is glioblastoma multiforme, which to date remains incurable. Thuja occidentalis is used in homeopathy for the treatment of cancer, however, its mechanism of action remains unknown. We set out to study the effects of thujone fractions of Thuja on glioblastoma using in vitro and in vivo models. We found that the α/ β -thujone fraction decrease the cell viability and exhibit a potent anti-proliferative, pro-apoptotic and anti-angiogenic effects in vitro. In vivo assays showed that α /β -thujone promotes the regression of neoplasia and inhibits the angiogenic markers VEGF, Ang-4 and CD31 into the tumor.
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pro apoptotic and anti angiogenic properties of the α β thujone fraction from Thuja occidentalis on glioblastoma cells
Journal of Neuro-oncology, 2016Co-Authors: Angelo Torres, Yosselyn Vargas, Cristian Carrasco, Cristian Torres, René Rocha, Rody San Martin, Ciro Oyarzún, Daniel Uribe, Claudia QuezadaAbstract:The most aggressive type of brain tumor is glioblastoma multiforme, which to date remains incurable. Thuja occidentalis is used in homeopathy for the treatment of cancer, however, its mechanism of action remains unknown. We set out to study the effects of thujone fractions of Thuja on glioblastoma using in vitro and in vivo models. We found that the α/β-thujone fraction decrease the cell viability and exhibit a potent anti-proliferative, pro-apoptotic and anti-angiogenic effects in vitro. In vivo assays showed that α/β-thujone promotes the regression of neoplasia and inhibits the angiogenic markers VEGF, Ang-4 and CD31 into the tumor.
Heyu Chen - One of the best experts on this subject based on the ideXlab platform.
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Application of Western red cedar (Thuja plicata) tree bark as a functional filler in pMDI wood adhesives
Industrial Crops and Products, 2018Co-Authors: Heyu Chen, Ning YanAbstract:Abstract In this study, Western red cedar (Thuja plicata) tree bark was used as a reactive functional filler (oven-dry particles,
Angelo Torres - One of the best experts on this subject based on the ideXlab platform.
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Pro-apoptotic and anti-angiogenic properties of the α /β-thujone fraction from Thuja occidentalis on glioblastoma cells
Journal of Neuro-Oncology, 2016Co-Authors: Angelo Torres, Yosselyn Vargas, Cristian Carrasco, Cristian Torres, René Rocha, Rody San Martín, Ciro Oyarzún, Daniel Uribe, Claudia QuezadaAbstract:The most aggressive type of brain tumor is glioblastoma multiforme, which to date remains incurable. Thuja occidentalis is used in homeopathy for the treatment of cancer, however, its mechanism of action remains unknown. We set out to study the effects of thujone fractions of Thuja on glioblastoma using in vitro and in vivo models. We found that the α/ β -thujone fraction decrease the cell viability and exhibit a potent anti-proliferative, pro-apoptotic and anti-angiogenic effects in vitro. In vivo assays showed that α /β -thujone promotes the regression of neoplasia and inhibits the angiogenic markers VEGF, Ang-4 and CD31 into the tumor.
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pro apoptotic and anti angiogenic properties of the α β thujone fraction from Thuja occidentalis on glioblastoma cells
Journal of Neuro-oncology, 2016Co-Authors: Angelo Torres, Yosselyn Vargas, Cristian Carrasco, Cristian Torres, René Rocha, Rody San Martin, Ciro Oyarzún, Daniel Uribe, Claudia QuezadaAbstract:The most aggressive type of brain tumor is glioblastoma multiforme, which to date remains incurable. Thuja occidentalis is used in homeopathy for the treatment of cancer, however, its mechanism of action remains unknown. We set out to study the effects of thujone fractions of Thuja on glioblastoma using in vitro and in vivo models. We found that the α/β-thujone fraction decrease the cell viability and exhibit a potent anti-proliferative, pro-apoptotic and anti-angiogenic effects in vitro. In vivo assays showed that α/β-thujone promotes the regression of neoplasia and inhibits the angiogenic markers VEGF, Ang-4 and CD31 into the tumor.
Amla Batra - One of the best experts on this subject based on the ideXlab platform.
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Role of Phenolics in Anti-Atherosclerotic Property of Thuja occidentalis Linn.
Ethnobotanical Leaflets, 2009Co-Authors: Sushil Kumar Dubey, Amla BatraAbstract:The present study was carried out to evaluate the Lipid peroxidation activity and related hypolipidaemic activity of an (EFTO) ethanol fraction of extract of aerial part of Thuja occidentalis Linn. (Cupressaceae). Lipid peroxidation activity was carried out to evaluate the antioxidant potential, and hypolipidaemic activity on cholesterol fed rats. The antioxidant activity of ethanol fraction was increased in a concentration dependent manner. About 100, 150, 200, 250 & 300 µg EFTO (ethanol fraction of extract of aerial part of Thuja occidentalis) inhibited the FeSO 4 induced lipid peroxidation in a dose dependent manner and showed IC 50 value 195.60µg/ml. in hypolipidaemic activity EFTO at the dose of 200 mg and 400mg/kg body weight significantly reduced serum cholesterol (77 and 92%), LDL (53 and 84%), triglycerides (27 and 46%). The increase in HDL to total cholesterol ratio and reduction in atherogenic index in EFTO treated groups strongly supports anti-atherosclerotic property of Thuja occidentalis. The results obtained in this study indicate that EFTO can be a potential source of natural antioxidant and activities related to this.
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Hepatoprotective Activity from Ethanol Fraction of Thuja occidentalis Linn.
Asian Journal of Research in Chemistry, 2008Co-Authors: Sushil Kumar Dubey, Amla BatraAbstract:Thuja occidentalis (Cupressaceae), commonly known as Arbor vitae or white cedar has been used in folk medicine to treat bronchial catarrh, enuresis, cystitis, psoriasis, uterine carcinomas, amenorrhea and rheumatism and is mainly used in homeopathy as mother tincture. Extract of this plant has shown anti oxidant, anti viral, anti diarrhoeal activity since this plant contains flavonoids, tannins and polysaccharides. The aim of the present investigation was to evaluate the possible hepatoprotective activity of Thuja occidentalis aerial part. The hepatoprotective potential effect of ethanolic fraction of Thuja occidentalis has been assessed against CCL4 induced liver damage in rats. A dose of EFTO 400 mg/kg p.o. exhibited significant protection from liver damage in acute and chronic CCL4 induced liver damage model. Histopathological examination was carried out after the treatment to evaluate hepato protection. The fraction was found to possess good hepatoprotective property.
