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Mark L Urken - One of the best experts on this subject based on the ideXlab platform.

  • collision tumor of the Thyroid and larynx a patient with papillary Thyroid carcinoma colliding with laryngeal squamous cell carcinoma
    Thyroid, 2008
    Co-Authors: Adam S Jacobson, Bruce M Wenig, Mark L Urken
    Abstract:

    BACKGROUND: The term "collision tumor" refers to the coexistence of two histologically distinct malignant tumors within the same Mass. Collision tumors involving the Thyroid gland and/or neck region are especially uncommon, with most reported cases involving papillary Thyroid carcinoma in coexistence with medullary Thyroid carcinoma, follicular carcinoma, and metastatic disease, the latter including a rare occurrence of metastatic liposarcoma and Thyroid papillary carcinoma. A collision tumor of papillary Thyroid carcinoma and squamous cell carcinoma primary to the Thyroid has also been reported. SUMMARY: We now report a collision tumor comprised of well-differentiated papillary Thyroid carcinoma and squamous cell carcinoma that originated as a laryngeal primary tumor. Histologically, the Thyroid Mass is consisted of well-differentiated papillary Thyroid carcinoma. The laryngeal Mass consisted of in situ and invasive squamous cell carcinoma. Both cancers were extensively infiltrative into the soft tissues of the neck and paraglottic space where the histologically distinct tumor types approximated one another but were not admixed with each other. Additionally, cervical lymph nodes showed metastatic carcinoma, including independent cervical lymph nodes with metastatic squamous cell carcinoma only, cervical lymph nodes with metastatic papillary Thyroid carcinoma only, and cervical lymph nodes with foci of both papillary Thyroid carcinoma and squamous cell carcinoma. CONCLUSION: As best we can determine this is the first publication of a collision tumor comprised of a well-differentiated papillary Thyroid carcinoma and squamous cell carcinoma that originated as a laryngeal primary tumor. For any patient with a Thyroid Mass that appears to be in continuity with a laryngeal Mass, more commonly one would find invasive Thyroid cancer, but one must consider a collision tumor in the differential diagnosis.

  • collision tumor of the Thyroid a case report of metastatic liposarcoma plus papillary Thyroid carcinoma
    Head and Neck-journal for The Sciences and Specialties of The Head and Neck, 2004
    Co-Authors: Mark L Urken, Margaret Brandweingensler, Beverly Y Wang
    Abstract:

    Background. The term collision tumor represents the proximal coexistence of two histologically distinct tumors. Collision tumors within the Thyroid are extremely rare, and reported cases are usually of mixed histologies of papillary and medullary carcinomas. Metastatic disease to the Thyroid is also an uncommon scenario but may develop after long disease-free intervals. Carcinomas, most commonly renal cell carcinoma, are the likeliest group of neoplasms to metastasize to the Thyroid. Soft tissue sarcomas metastasize to the Thyroid with a much lower frequency. Methods. We are reporting this highly unusual case of metastatic liposarcoma from the thigh to Thyroid, which harbored a collision tumor of papillary Thyroid carcinoma. This 86-year-old woman had undergone an initial resection for liposarcoma of the thigh two decades before being seen with a Thyroid Mass. Results. Histologically, the Thyroid Mass was a metastatic myxoid liposarcoma, identical to the primary neoplasm. Papillary Thyroid carcinoma was present within this metastasis and in the adjacent Thyroid. Conclusion. For any patient seen with a Thyroid Mass with a history of prior malignancy, no matter how remote, metastatic disease should be considered in the differential diagnosis. © 2004 Wiley Periodicals, Inc. Head Neck26: 637–641, 2004

Prasanta Kumar Gure - One of the best experts on this subject based on the ideXlab platform.

  • primary embryonal rhabdomyosarcoma of the anterior neck and Thyroid
    Laryngoscope, 2013
    Co-Authors: Mainak Dutta, Indranil Chatterjee, Prasanta Kumar Gure
    Abstract:

    : Primary embryonal rhabdomyosarcoma of anterior neck involving the Thyroid is extremely rare. This report is only the second of its kind that describes this form of nonorbital nonparameningeal rhabdomyosarcoma in a 7-year-old boy and adds to a new, seldom-reported variant of rhabdomyosarcoma in the head-neck region. The child presented with a huge anterior neck swelling that clinically resembled a Thyroid Mass. Computed tomography scan showed a heterogeneous Mass in the anterior neck replacing the entire right lobe of Thyroid. Fine-needle aspiration cytology was nondiagnostic. Right hemiThyroidectomy with selective neck dissection suggested embryonal rhabdomyosarcoma by histopathology; the diagnosis was confirmed by positive reactions to desmin and myogenin. The child was subsequently treated with chemotherapy. Repeat chemotherapy with radiotherapy was required when recurrences were detected in the mediastinum and cervical lymph nodes at 13-month follow-up.

Prasanta Kumar Gure Ms - One of the best experts on this subject based on the ideXlab platform.

  • primary embryonal rhabdomyosarcoma of the anterior neck and Thyroid
    Laryngoscope, 2013
    Co-Authors: Mainak Dutta Ms, Soham Roy Md Facs Faap, Prasanta Kumar Gure Ms
    Abstract:

    Primary embryonal rhabdomyosarcoma of anterior neck involving the Thyroid is extremely rare. This report is only the second of its kind that describes this form of nonorbital nonparameningeal rhabdomyosarcoma in a 7-year-old boy and adds to a new, seldom-reported variant of rhabdomyosarcoma in the head-neck region. The child presented with a huge anterior neck swelling that clinically resembled a Thyroid Mass. Computed tomography scan showed a heterogeneous Mass in the anterior neck replacing the entire right lobe of Thyroid. Fine-needle aspiration cytology was nondiagnostic. Right hemiThyroidectomy with selective neck dissection suggested embryonal rhabdomyosarcoma by histopathology; the diagnosis was confirmed by positive reactions to desmin and myogenin. The child was subsequently treated with chemotherapy. Repeat chemotherapy with radiotherapy was required when recurrences were detected in the mediastinum and cervical lymph nodes at 13-month follow-up. Laryngoscope, 123:2072–2076, 2013

Margaret Brandweingensler - One of the best experts on this subject based on the ideXlab platform.

  • collision tumor of the Thyroid a case report of metastatic liposarcoma plus papillary Thyroid carcinoma
    Head and Neck-journal for The Sciences and Specialties of The Head and Neck, 2004
    Co-Authors: Mark L Urken, Margaret Brandweingensler, Beverly Y Wang
    Abstract:

    Background. The term collision tumor represents the proximal coexistence of two histologically distinct tumors. Collision tumors within the Thyroid are extremely rare, and reported cases are usually of mixed histologies of papillary and medullary carcinomas. Metastatic disease to the Thyroid is also an uncommon scenario but may develop after long disease-free intervals. Carcinomas, most commonly renal cell carcinoma, are the likeliest group of neoplasms to metastasize to the Thyroid. Soft tissue sarcomas metastasize to the Thyroid with a much lower frequency. Methods. We are reporting this highly unusual case of metastatic liposarcoma from the thigh to Thyroid, which harbored a collision tumor of papillary Thyroid carcinoma. This 86-year-old woman had undergone an initial resection for liposarcoma of the thigh two decades before being seen with a Thyroid Mass. Results. Histologically, the Thyroid Mass was a metastatic myxoid liposarcoma, identical to the primary neoplasm. Papillary Thyroid carcinoma was present within this metastasis and in the adjacent Thyroid. Conclusion. For any patient seen with a Thyroid Mass with a history of prior malignancy, no matter how remote, metastatic disease should be considered in the differential diagnosis. © 2004 Wiley Periodicals, Inc. Head Neck26: 637–641, 2004

Soham Roy Md Facs Faap - One of the best experts on this subject based on the ideXlab platform.

  • primary embryonal rhabdomyosarcoma of the anterior neck and Thyroid
    Laryngoscope, 2013
    Co-Authors: Mainak Dutta Ms, Soham Roy Md Facs Faap, Prasanta Kumar Gure Ms
    Abstract:

    Primary embryonal rhabdomyosarcoma of anterior neck involving the Thyroid is extremely rare. This report is only the second of its kind that describes this form of nonorbital nonparameningeal rhabdomyosarcoma in a 7-year-old boy and adds to a new, seldom-reported variant of rhabdomyosarcoma in the head-neck region. The child presented with a huge anterior neck swelling that clinically resembled a Thyroid Mass. Computed tomography scan showed a heterogeneous Mass in the anterior neck replacing the entire right lobe of Thyroid. Fine-needle aspiration cytology was nondiagnostic. Right hemiThyroidectomy with selective neck dissection suggested embryonal rhabdomyosarcoma by histopathology; the diagnosis was confirmed by positive reactions to desmin and myogenin. The child was subsequently treated with chemotherapy. Repeat chemotherapy with radiotherapy was required when recurrences were detected in the mediastinum and cervical lymph nodes at 13-month follow-up. Laryngoscope, 123:2072–2076, 2013