The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform
Eric Cormier - One of the best experts on this subject based on the ideXlab platform.
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Every single-shot CEP drift detection for near-infrared lasers with modified Toucan method
OSA High-brightness Sources and Light-driven Interactions Congress 2020 (EUVXRAY HILAS MICS), 2020Co-Authors: Kurucz Máté, Tóth Szabolcs, Kiss Balint, Csontos Janos, Eric CormierAbstract:The original Toucan device is capable of single-shot CEP drift measurement of ~3 pm lasers at arbitrary repetition rate. We have expanded this technique for near-infrared lasers and crosschecked results with a traditional measurement method.
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Single-shot CEP drift measurement at arbitrary repetition rate based on dispersive Fourier transform
Optics Express, 2019Co-Authors: Máté Kurucz, Szabolcs Tóth, Roland Flender, Ludovít Haizer, Balint Kiss, Benjamin Persielle, Eric CormierAbstract:This paper presents a single-shot technique for measuring CEP. The Temporal dispersion based One-shot Ultrafast Carrier envelope phase Analysis method (Toucan) is an arbitrary repetition rate single-shot CEP drift measurement technique based on dispersive Fourier transformations and has been experimentally tested at 100 kHz. Toucan was validated by a direct comparison of decimated data with an independent traditional CEP drift measurement technique. The impact of a temporal jitter on the CEP drift measurement is investigated and a new mitigation technique is shown to produce high accuracy jitter-free CEP drift extraction.
Jean-louis Couderc - One of the best experts on this subject based on the ideXlab platform.
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The Drosophila Toucan protein is a new mitotic microtubule-associated protein required for spindle microtubule stability.
Genes to cells : devoted to molecular & cellular mechanisms, 2004Co-Authors: Vincent Mirouse, Bernard Dastugue, Jean-louis CoudercAbstract:Mitotic spindle dynamics are highly dependent on proteins that interact with microtubules to influence their organization or stability. Here, we show that the Drosophila Toucan protein interacts directly with microtubules. Its localization to the microtubule network when it is expressed in mammalian cells and its direct interaction with microtubules in vitro are dependent on its central basic domain. Moreover, Toc expression in mammalian cells strongly protects microtubules from depolymerization. By using in vivo inducible RNAi in syncytial embryos, we generated a dose-sensitive loss of function of Toucan, demonstrating that this technique is an efficient method for inactivating a maternal transcript. This enabled us to accurately characterize several new mitotic defects from the early to the late phases of mitosis, depending on Toucan depletion level. Toucan is required for metaphase spindle formation and centrosome anchoring to the poles. Then, during anaphase, Toc depletion affects kinetochore microtubules and therefore chromosome segregation. Toc is also necessary for central spindle formation by the interpolar microtubules. In contrast, astral microtubules are not disturbed by Toc depletion. Taken together, our results show that Toucan is a microtubule-associated protein specifically required for the stability of spindle microtubules throughout mitosis.
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Toucan protein is essential for the assembly of syncytial mitotic spindles in Drosophila melanogaster
Genesis (New York N.Y. : 2000), 2001Co-Authors: A Debec, Muriel Grammont, Bernard Dastugue, G Berson, William J. Sullivan, Jean-louis CoudercAbstract:Summary: The toc gene of Drosophila melanogaster encodes a 235-kD polypeptide with a coiled-coil domain, which is highly expressed during oogenesis (Grammont et al., 1997, 2000). We now report the localization of the Toucan protein during early embryonic development. The Toucan protein is present only during the syncytial stages and is associated with the nuclear envelope and the cytoskeletal structures of the syncytial embryo. In anaphase A, Toucan is concentrated at the spindle poles near the minus end of microtubules. This microtubule association is very dynamic during the nuclear cell cycle. Mutant embryos lacking the Toucan protein are blocked in a metaphase-like state. They display abnormal and nonfunctional spindles, characterized by broad poles, detachment of the centrosomes, and failure of migration of the chromosomes. These results strongly suggest that Toucan represents a factor essential for the assembly and the function of the syncytial mitotic spindles. genesis 31:167–175, 2001. © 2001 Wiley-Liss, Inc.
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Expression and cellular localization of the Toucan protein during Drosophila oogenesis.
Mechanisms of development, 2000Co-Authors: Muriel Grammont, Bernard Dastugue, G Berson, Jean-louis CoudercAbstract:The Toucan (toc) gene is required in the germline for somatic cell patterning during Drosophila oogenesis. To better understand the function of toc, we performed a detailed analysis of the distribution of the Toucan protein during oogenesis. Toc expression is restricted to the germline cells and shows a dynamic distribution pattern throughout follicle development. Mislocalization of the Toc protein in mutant follicles in which the microtubule network is altered indicates that microtubules play a role in Toc localization during oogenesis.
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Gene expression pattern Expression and cellular localization of the Toucan protein during Drosophila oogenesis
2000Co-Authors: Muriel Grammont, Bernard Dastugue, G Berson, Jean-louis CoudercAbstract:The Toucan (toc) gene is required in the germline for somatic cell patterning during Drosophila oogenesis. To better understand the function of toc, we performed a detailed analysis of the distribution of the Toucan protein during oogenesis. Toc expression is restricted to the germline cells and shows a dynamic distribution pattern throughout follicle development. Mislocalization of the Toc protein in mutant follicles in which the microtubule network is altered indicates that microtubules play a role in Toc localization during oogenesis. q 2000 Elsevier Science Ireland Ltd. All rights reserved.
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The Drosophila Toucan (toc) gene is required in germline cells for the somatic cell patterning during oogenesis.
Development (Cambridge England), 1997Co-Authors: Muriel Grammont, Bernard Dastugue, Jean-louis CoudercAbstract:We have characterized a new gene, called Toucan, that is expressed and required in germline cells to promote proper differentiation of the somatic follicle cells. Toucan mutant ovaries are defective in (i) the enclosure of newly formed germline cysts by the follicle cells, (ii) the formation of interfollicular stalks, (iii) the migration of the follicle cells over the oocyte and (iv) the formation of the eggshell. Overexpression of a Toucan cDNA in the germline leads to the production of longer interfollicular stalks than wild-type ovaries, a phenotype that is the exact opposite of the Toucan mutant phenotype. This observation shows that the formation of the interfollicular stalks depends not only on interactions among the somatic cells but also requires a germline signal. Moreover, dominant interactions have been observed between Toucan and certain alleles of the daughterless, Notch and Delta genes, each of which is required in the somatic cells for the formation of egg chambers. Toucan encodes for a large protein with a coiled-coil domain but has no other homology with known proteins. We propose that Toucan participates in the production or localization of a germline-specific signal(s) that is required for the patterning of the follicular epithelium.
J Couderc - One of the best experts on this subject based on the ideXlab platform.
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Toucan protein is essential for the assembly of syncytial mitotic spindles in Drosophila melanogaster.
Genesis, 2001Co-Authors: A Debec, M Grammont, G Berson, B Dastugue, W Sullivan, J CoudercAbstract:The toc gene of Drosophila melanogaster encodes a 235-kD polypeptide with a coiled-coil domain, which is highly expressed during oogenesis (Grammont et al., 1997, 2000). We now report the localization of the Toucan protein during early embryonic development. The Toucan protein is present only during the syncytial stages and is associated with the nuclear envelope and the cytoskeletal structures of the syncytial embryo. In anaphase A, Toucan is concentrated at the spindle poles near the minus end of microtubules. This microtubule association is very dynamic during the nuclear cell cycle. Mutant embryos lacking the Toucan protein are blocked in a metaphase-like state. They display abnormal and nonfunctional spindles, characterized by broad poles, detachment of the centrosomes, and failure of migration of the chromosomes. These results strongly suggest that Toucan represents a factor essential for the assembly and the function of the syncytial mitotic spindles.
Scott B. Baden - One of the best experts on this subject based on the ideXlab platform.
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Toucan a translator for communication tolerant mpi applications
International Parallel and Distributed Processing Symposium, 2017Co-Authors: Sergio Martín, Marsha Berger, Scott B. BadenAbstract:We discuss early results with Toucan, a source-to-source translatorthat automatically restructures C/C++ MPI applications tooverlap communication with computation. We co-designed thetranslator and runtime system to enable dynamic, dependence-drivenexecution of MPI applications, and require only a modest amount ofprogrammer annotation. Co-design was essential to realizingoverlap through dynamic code block reordering and avoiding the limitations of static code relocation and inlining. We demonstrate that Toucan hides significantcommunication in four representative applications running on up to 24Kcores of NERSC's Edison platform. Using Toucan, we have hidden from 33% to 85% of the communication overhead, with performance meeting or exceeding that of painstakingly hand-written overlap variants.
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IPDPS - Toucan — A Translator for Communication Tolerant MPI Applications
2017 IEEE International Parallel and Distributed Processing Symposium (IPDPS), 2017Co-Authors: Sergio Martín, Marsha Berger, Scott B. BadenAbstract:We discuss early results with Toucan, a source-to-source translatorthat automatically restructures C/C++ MPI applications tooverlap communication with computation. We co-designed thetranslator and runtime system to enable dynamic, dependence-drivenexecution of MPI applications, and require only a modest amount ofprogrammer annotation. Co-design was essential to realizingoverlap through dynamic code block reordering and avoiding the limitations of static code relocation and inlining. We demonstrate that Toucan hides significantcommunication in four representative applications running on up to 24Kcores of NERSC's Edison platform. Using Toucan, we have hidden from 33% to 85% of the communication overhead, with performance meeting or exceeding that of painstakingly hand-written overlap variants.
Jorge A. Lobo - One of the best experts on this subject based on the ideXlab platform.
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Toucans (Ramphastos ambiguus) facilitate resilience against seed dispersal limitation to a large-seeded tree (Virola surinamensis) in a human-modified landscape
Biotropica, 2017Co-Authors: Juan I. Moreira, Pablo Riba-hernández, Jorge A. LoboAbstract:Large-seeded plants may suffer seed dispersal limitation in human-modified landscapes if seed dispersers are absent or unable to disperse their seeds. We investigated dispersal limitation for the large-seeded tree Virola surinamensis in a human-modified landscape in southern Costa Rica. During two fruiting seasons, we monitored crop size, seed removal rates, the number of fruiting conspecifics within 100 m, and feeding visitation rates by frugivores at trees located in high and low forest disturbance conditions. Seed removal rates and the total number of seeds removed were high regardless of the disturbance level, but these parameters increased with tree crop size and decreased with the number of fruiting V. surinamensis trees within a 100 m radius. Trees at low disturbance levels were more likely to be visited by seed dispersers. Black mandibled Toucans (Ramphastos ambiguus) and spider monkeys (Ateles geoffroyi) were the most important seed dispersers, based on visitation patterns and seed removal rates. Spider monkey feeding visits were more frequent at high disturbance levels, but the monkeys preferentially visited isolated trees with large yields and surrounded by a low number of fruiting Virola trees within 100 m. Toucan visitation patterns were not constrained by any of the predictors and they visited trees equally across the landscape. We suggest that isolated and highly fecund Virola trees are an important food resource for spider monkeys in human-modified landscapes and that Toucans can provide resilience against seed dispersal limitations for large-seeded plants in human-modified landscapes in the absence of hunting.
