The Experts below are selected from a list of 321 Experts worldwide ranked by ideXlab platform
Veit Roessner - One of the best experts on this subject based on the ideXlab platform.
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action inhibition in Tourette Syndrome
Movement Disorders, 2014Co-Authors: Christos Ganos, Tobias Bäumer, Veit Roessner, Simone Kuhn, Ursula Kahl, Odette Schunke, Jan Feldheim, Christian Gerloff, Gotz Thomalla, Patrick HaggardAbstract:Tourette Syndrome is a neuropsychiatric disorder characterized by tics. Tic generation is often linked to dysfunction of inhibitory brain networks. Some previous behavioral studies found deficiencies in inhibitory motor control in Tourette Syndrome, but others suggested normal or even better-than-normal performance. Furthermore, neural correlates of action inhibition in these patients are poorly understood. We performed event-related functional magnetic resonance imaging during a stop-signal reaction-time task in 14 uncomplicated adult Tourette patients and 15 healthy controls. In patients, we correlated activations in stop-signal reaction-time task with their individual motor tic frequency. Task performance was similar in both groups. Activation of dorsal premotor cortex was stronger in the StopSuccess than in the Go condition in healthy controls. This pattern was reversed in Tourette patients. A significant positive correlation was present between motor tic frequency and activations in the supplementary motor area during StopSuccess versus Go in patients. Inhibitory brain networks differ between healthy controls and Tourette patients. In the latter the supplementary motor area is probably a key relay of inhibitory processes mediating both suppression of tics and inhibition of voluntary action. © 2014 International Parkinson and Movement Disorder Society
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fine motor skills and interhemispheric transfer in treatment naive male children with Tourette Syndrome
Developmental Medicine & Child Neurology, 2012Co-Authors: Judith Buse, Julia M. August, Nathalie Bock, Denise Dörfel, Aribert Rothenberger, Veit RoessnerAbstract:Aim This study addressed whether Tourette Syndrome is associated with an impairment of fine motor skills or altered interhemispheric transfer. We additionally investigated the association between interhemispheric transfer and size of the corpus callosum. Method The sample, a subsample of our larger neuroimaging sample, included 27 treatment-naive males with ‘pure’ Tourette Syndrome (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 2mo) and 26 matched healthy comparison children (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 1mo). A finger tapping task and the Purdue Pegboard were used to assess fine motor skills. Interhemispheric transfer time (ITT) was measured with the Poffenberger paradigm. The neuroanatomical data were derived from our previous neuroimaging study. Results ITT was negatively correlated with the size of callosal subregion 3 (r=−0.366, p=0.028), indicating that a shorter ITT was associated with a larger corpus callosum. Interpretation Our findings support the assumption that previously reported impairment of motor skills in Tourette Syndrome does not directly result from tics but from other factors such as medication or comorbidities. Following the assumption that callosal subregion 3 in Tourette Syndrome grows as a consequence of tic performance over years, our preliminary results suggest that this growth might accelerate interhemispheric transfer in Tourette Syndrome.
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Fine motor skills and interhemispheric transfer in treatment‐naive male children with Tourette Syndrome
Developmental medicine and child neurology, 2012Co-Authors: Judith Buse, Julia M. August, Nathalie Bock, Denise Dörfel, Aribert Rothenberger, Veit RoessnerAbstract:Aim This study addressed whether Tourette Syndrome is associated with an impairment of fine motor skills or altered interhemispheric transfer. We additionally investigated the association between interhemispheric transfer and size of the corpus callosum. Method The sample, a subsample of our larger neuroimaging sample, included 27 treatment-naive males with ‘pure’ Tourette Syndrome (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 2mo) and 26 matched healthy comparison children (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 1mo). A finger tapping task and the Purdue Pegboard were used to assess fine motor skills. Interhemispheric transfer time (ITT) was measured with the Poffenberger paradigm. The neuroanatomical data were derived from our previous neuroimaging study. Results ITT was negatively correlated with the size of callosal subregion 3 (r=−0.366, p=0.028), indicating that a shorter ITT was associated with a larger corpus callosum. Interpretation Our findings support the assumption that previously reported impairment of motor skills in Tourette Syndrome does not directly result from tics but from other factors such as medication or comorbidities. Following the assumption that callosal subregion 3 in Tourette Syndrome grows as a consequence of tic performance over years, our preliminary results suggest that this growth might accelerate interhemispheric transfer in Tourette Syndrome.
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Coprophenomena in Tourette Syndrome.
Developmental medicine and child neurology, 2008Co-Authors: Roger D. Freeman, Aribert Rothenberger, Veit Roessner, Jacob Kerbeshian, Larry Burd, Kirsten Müller-vahl, Yukiko Kano, Samuel H. Zinner, Diane K. Fast, Jeremy S. SternAbstract:The aims of this descriptive study were to examine the prevalence and associations of coprophenomena (involuntary expression of socially unacceptable words or gestures) in individuals with Tourette Syndrome. Participant data were obtained from the Tourette Syndrome International Database Consortium. A specialized data collection form was completed for each of a subset of 597 consecutive new patients with Tourette Syndrome from 15 sites in seven countries. Coprolalia occurred at some point in the lifetime of 19.3% of males and 14.6% of females, and copropraxia in 5.9% of males and 4.9% of females. Coprolalia was three times as frequent as copropraxia, with a mean onset of each at about 11 years, 5 years after the onset of tics. In 11% of those with coprolalia and 12% of those with copropraxia these coprophenomena were one of the initial symptoms of Tourette Syndrome. The onsets of tics, coprophenomena, smelling of non-food objects, and spitting were strongly intercorrelated. Early onset of coprophenomena was not associated with its longer persistence. The most robust associations of coprophenomena were with the number of non-tic repetitive behaviors, spitting, and inappropriate sexual behavior. Although coprophenomena are a frequently feared possibility in the course of Tourette Syndrome, their emergence occurs in only about one in five referred patients. Because the course and actual impact of coprophenomena are variable, additional prospective research is needed to provide better counseling and prognostic information.
Judith Buse - One of the best experts on this subject based on the ideXlab platform.
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fine motor skills and interhemispheric transfer in treatment naive male children with Tourette Syndrome
Developmental Medicine & Child Neurology, 2012Co-Authors: Judith Buse, Julia M. August, Nathalie Bock, Denise Dörfel, Aribert Rothenberger, Veit RoessnerAbstract:Aim This study addressed whether Tourette Syndrome is associated with an impairment of fine motor skills or altered interhemispheric transfer. We additionally investigated the association between interhemispheric transfer and size of the corpus callosum. Method The sample, a subsample of our larger neuroimaging sample, included 27 treatment-naive males with ‘pure’ Tourette Syndrome (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 2mo) and 26 matched healthy comparison children (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 1mo). A finger tapping task and the Purdue Pegboard were used to assess fine motor skills. Interhemispheric transfer time (ITT) was measured with the Poffenberger paradigm. The neuroanatomical data were derived from our previous neuroimaging study. Results ITT was negatively correlated with the size of callosal subregion 3 (r=−0.366, p=0.028), indicating that a shorter ITT was associated with a larger corpus callosum. Interpretation Our findings support the assumption that previously reported impairment of motor skills in Tourette Syndrome does not directly result from tics but from other factors such as medication or comorbidities. Following the assumption that callosal subregion 3 in Tourette Syndrome grows as a consequence of tic performance over years, our preliminary results suggest that this growth might accelerate interhemispheric transfer in Tourette Syndrome.
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Fine motor skills and interhemispheric transfer in treatment‐naive male children with Tourette Syndrome
Developmental medicine and child neurology, 2012Co-Authors: Judith Buse, Julia M. August, Nathalie Bock, Denise Dörfel, Aribert Rothenberger, Veit RoessnerAbstract:Aim This study addressed whether Tourette Syndrome is associated with an impairment of fine motor skills or altered interhemispheric transfer. We additionally investigated the association between interhemispheric transfer and size of the corpus callosum. Method The sample, a subsample of our larger neuroimaging sample, included 27 treatment-naive males with ‘pure’ Tourette Syndrome (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 2mo) and 26 matched healthy comparison children (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 1mo). A finger tapping task and the Purdue Pegboard were used to assess fine motor skills. Interhemispheric transfer time (ITT) was measured with the Poffenberger paradigm. The neuroanatomical data were derived from our previous neuroimaging study. Results ITT was negatively correlated with the size of callosal subregion 3 (r=−0.366, p=0.028), indicating that a shorter ITT was associated with a larger corpus callosum. Interpretation Our findings support the assumption that previously reported impairment of motor skills in Tourette Syndrome does not directly result from tics but from other factors such as medication or comorbidities. Following the assumption that callosal subregion 3 in Tourette Syndrome grows as a consequence of tic performance over years, our preliminary results suggest that this growth might accelerate interhemispheric transfer in Tourette Syndrome.
Jonathan W. Mink - One of the best experts on this subject based on the ideXlab platform.
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Progress in research on Tourette Syndrome
Journal of obsessive-compulsive and related disorders, 2014Co-Authors: Kevin J. Black, Jonathan W. Mink, Joseph Jankovic, Kevin St. P. Mcnaught, Tamara Hershey, John T. WalkupAbstract:Tourette Syndrome (TS) is a heritable neuropsychiatric disorder commonly complicated by obsessions and compulsions, but defined by frequent unwanted movements (motor tics) and vocalizations (phonic tics) that develop in childhood or adolescence. In recent years, research on TS has progressed rapidly on several fronts. Inspired by the Fifth International Scientific Symposium on Tourette Syndrome, the articles in this special issue review advances in the phenomenology, epidemiology, genetics, pathophysiology, and treatment of TS.
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Advances in understanding and treatment of Tourette Syndrome
Nature Reviews Neurology, 2011Co-Authors: Kevin St. P. Mcnaught, Jonathan W. MinkAbstract:Tourette Syndrome is a hereditary, childhood-onset neurodevelopmental disorder that was first clearly described in France in 1885. This disorder is characterized by sudden, rapid, recurrent, nonrhythmic movements (motor tics) or sounds (vocal or phonic tics), often preceded by premonitory sensations or urges. Some individuals also have psychiatric comorbidities, notably attention-deficit hyperactivity disorder or obsessive–compulsive disorder. Tourette Syndrome occurs worldwide, in all races and ethnicities, in both sexes and in children as well as in adults. Estimates of its prevalence in children vary, with rates of up to 1% being reported, but rates of 0.3–0.8% are thought to accurately reflect the occurrence of the disorder. Research has led to progress in many aspects of Tourette Syndrome, although many questions and unmet needs remain. For example, except for rare cases, the genetic basis remains elusive. The anatomical and neuronal changes in the brain that underlie Tourette Syndrome are also unclear, although the evidence increasingly implicates alterations in basal ganglia function. Treatment is often unnecessary for individuals with mild tics, but for those with moderate to severe forms of the Syndrome, some drugs are available, albeit frequently ineffective. Behavioral and surgical therapies, in particular deep brain stimulation, are currently undergoing development and show promising results. This Review examines the history of Tourette Syndrome and describes its clinical presentation. The article also provides an overview of the epidemiology and pathophysiology of this disorder. Current treatment strategies and potential future therapies are also discussed. Tourette Syndrome is a hereditary, childhood-onset neurodevelopmental disorder that was first clearly described in 1885 Tourette Syndrome is clinically characterized by sudden, rapid, recurrent, nonrhythmic movements (motor tics) or sounds (vocal or phonic tics), which are often accompanied by psychiatric comorbidities The genetic basis of Tourette Syndrome is not well-elucidated and, except for rare cases, the underlying mutations remain elusive The pathophysiology of Tourette Syndrome remains unclear, although increasing evidence suggests a role for alterations in basal ganglia function Pharmacological treatments are available, but are often ineffective; behavioral and surgical therapies are undergoing development and have shown promising results Future research into Tourette Syndrome should focus on investigating the pathophysiology of disease, development of suitable animal models and discovery of safe and effective therapies Tourette Syndrome, characterized by motor or vocal tics, is a multifactorial neurodevelopmental disorder that affects up to 1% of children and adults worldwide. In this Review, McNaught and Mink describe the history of Tourette Syndrome and its clinical presentation, and provide an overview of its epidemiology and pathophysiology. Current treatment strategies and potential future therapies are also discussed.
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Advances in understanding and treatment of Tourette Syndrome
Nature reviews. Neurology, 2011Co-Authors: Kevin St. P. Mcnaught, Jonathan W. MinkAbstract:Tourette Syndrome is a hereditary, childhood-onset neurodevelopmental disorder that was first clearly described in France in 1885. This disorder is characterized by sudden, rapid, recurrent, nonrhythmic movements (motor tics) or sounds (vocal or phonic tics), often preceded by premonitory sensations or urges. Some individuals also have psychiatric comorbidities, notably attention-deficit hyperactivity disorder or obsessive-compulsive disorder. Tourette Syndrome occurs worldwide, in all races and ethnicities, in both sexes and in children as well as in adults. Estimates of its prevalence in children vary, with rates of up to 1% being reported, but rates of 0.3-0.8% are thought to accurately reflect the occurrence of the disorder. Research has led to progress in many aspects of Tourette Syndrome, although many questions and unmet needs remain. For example, except for rare cases, the genetic basis remains elusive. The anatomical and neuronal changes in the brain that underlie Tourette Syndrome are also unclear, although the evidence increasingly implicates alterations in basal ganglia function. Treatment is often unnecessary for individuals with mild tics, but for those with moderate to severe forms of the Syndrome, some drugs are available, albeit frequently ineffective. Behavioral and surgical therapies, in particular deep brain stimulation, are currently undergoing development and show promising results. This Review examines the history of Tourette Syndrome and describes its clinical presentation. The article also provides an overview of the epidemiology and pathophysiology of this disorder. Current treatment strategies and potential future therapies are also discussed.
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Tourette Syndrome Research
Journal of Child Neurology, 2006Co-Authors: Jonathan W. Mink, Peter J. Hollenbeck, Neal R. Swerdlow, Sue Levi-pearlAbstract:The Tourette Syndrome Association was pleased to partner with the Child Neurology Society and the National Institutes of Health (NIH) in support of the symposium on Tourette Syndrome in the ‘‘Neurobiology of Diseases in Children’’ series. The symposium program offered highlights of some of the impressive gains that have been made in Tourette Syndrome research over the past decade. As with this symposium, much of this progress would not have occurred were it not for the support of the Tourette Syndrome Association, often in partnership with the National Institutes of Health. For over two decades, the Tourette Syndrome Association has actively funded research on genetics, neuroimaging, neuropathology, and clinical studies related to treatment of Tourette Syndrome. In addition, the Tourette Syndrome Association has supported the formation of several international consortia to perform collaborative research beyond what would have been possible for individual investigators working alone. The symposium represented the truly remarkable scientific spectrum of Tourette Syndrome, a disorder that spans the disciplines of neurology, psychiatry, psychology, genetics, and neuroscience. The breadth and depth of interest in Tourette Syndrome research and treatment were demonstrated well by the diversity of the invited faculty and by the attendance of more than 270 registrants. We were extremely gratified by both the quality of this symposium and the level of interest among participants. The work goes on. The first gene mutation associated with Tourette Syndrome has now been reported. Increased knowledge of the clinical and neurobiologic features of Tourette Syndrome has provided the rationale for new treatment strategies, some of which have already proven to be successful in controlled trials. The future for people with Tourette Syndrome is brighter than ever. Our support for this symposium was made possible by our member donors, a truly dedicated group of individuals who are committed to advancing research and treatment of this complex, challenging, and troublesome disorder.
Aribert Rothenberger - One of the best experts on this subject based on the ideXlab platform.
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fine motor skills and interhemispheric transfer in treatment naive male children with Tourette Syndrome
Developmental Medicine & Child Neurology, 2012Co-Authors: Judith Buse, Julia M. August, Nathalie Bock, Denise Dörfel, Aribert Rothenberger, Veit RoessnerAbstract:Aim This study addressed whether Tourette Syndrome is associated with an impairment of fine motor skills or altered interhemispheric transfer. We additionally investigated the association between interhemispheric transfer and size of the corpus callosum. Method The sample, a subsample of our larger neuroimaging sample, included 27 treatment-naive males with ‘pure’ Tourette Syndrome (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 2mo) and 26 matched healthy comparison children (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 1mo). A finger tapping task and the Purdue Pegboard were used to assess fine motor skills. Interhemispheric transfer time (ITT) was measured with the Poffenberger paradigm. The neuroanatomical data were derived from our previous neuroimaging study. Results ITT was negatively correlated with the size of callosal subregion 3 (r=−0.366, p=0.028), indicating that a shorter ITT was associated with a larger corpus callosum. Interpretation Our findings support the assumption that previously reported impairment of motor skills in Tourette Syndrome does not directly result from tics but from other factors such as medication or comorbidities. Following the assumption that callosal subregion 3 in Tourette Syndrome grows as a consequence of tic performance over years, our preliminary results suggest that this growth might accelerate interhemispheric transfer in Tourette Syndrome.
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Fine motor skills and interhemispheric transfer in treatment‐naive male children with Tourette Syndrome
Developmental medicine and child neurology, 2012Co-Authors: Judith Buse, Julia M. August, Nathalie Bock, Denise Dörfel, Aribert Rothenberger, Veit RoessnerAbstract:Aim This study addressed whether Tourette Syndrome is associated with an impairment of fine motor skills or altered interhemispheric transfer. We additionally investigated the association between interhemispheric transfer and size of the corpus callosum. Method The sample, a subsample of our larger neuroimaging sample, included 27 treatment-naive males with ‘pure’ Tourette Syndrome (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 2mo) and 26 matched healthy comparison children (age range 10y 2mo–14y 4mo; mean age 11y 10mo, SD 1y 1mo). A finger tapping task and the Purdue Pegboard were used to assess fine motor skills. Interhemispheric transfer time (ITT) was measured with the Poffenberger paradigm. The neuroanatomical data were derived from our previous neuroimaging study. Results ITT was negatively correlated with the size of callosal subregion 3 (r=−0.366, p=0.028), indicating that a shorter ITT was associated with a larger corpus callosum. Interpretation Our findings support the assumption that previously reported impairment of motor skills in Tourette Syndrome does not directly result from tics but from other factors such as medication or comorbidities. Following the assumption that callosal subregion 3 in Tourette Syndrome grows as a consequence of tic performance over years, our preliminary results suggest that this growth might accelerate interhemispheric transfer in Tourette Syndrome.
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Coprophenomena in Tourette Syndrome.
Developmental medicine and child neurology, 2008Co-Authors: Roger D. Freeman, Aribert Rothenberger, Veit Roessner, Jacob Kerbeshian, Larry Burd, Kirsten Müller-vahl, Yukiko Kano, Samuel H. Zinner, Diane K. Fast, Jeremy S. SternAbstract:The aims of this descriptive study were to examine the prevalence and associations of coprophenomena (involuntary expression of socially unacceptable words or gestures) in individuals with Tourette Syndrome. Participant data were obtained from the Tourette Syndrome International Database Consortium. A specialized data collection form was completed for each of a subset of 597 consecutive new patients with Tourette Syndrome from 15 sites in seven countries. Coprolalia occurred at some point in the lifetime of 19.3% of males and 14.6% of females, and copropraxia in 5.9% of males and 4.9% of females. Coprolalia was three times as frequent as copropraxia, with a mean onset of each at about 11 years, 5 years after the onset of tics. In 11% of those with coprolalia and 12% of those with copropraxia these coprophenomena were one of the initial symptoms of Tourette Syndrome. The onsets of tics, coprophenomena, smelling of non-food objects, and spitting were strongly intercorrelated. Early onset of coprophenomena was not associated with its longer persistence. The most robust associations of coprophenomena were with the number of non-tic repetitive behaviors, spitting, and inappropriate sexual behavior. Although coprophenomena are a frequently feared possibility in the course of Tourette Syndrome, their emergence occurs in only about one in five referred patients. Because the course and actual impact of coprophenomena are variable, additional prospective research is needed to provide better counseling and prognostic information.
John T. Walkup - One of the best experts on this subject based on the ideXlab platform.
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Progress in research on Tourette Syndrome
Journal of obsessive-compulsive and related disorders, 2014Co-Authors: Kevin J. Black, Jonathan W. Mink, Joseph Jankovic, Kevin St. P. Mcnaught, Tamara Hershey, John T. WalkupAbstract:Tourette Syndrome (TS) is a heritable neuropsychiatric disorder commonly complicated by obsessions and compulsions, but defined by frequent unwanted movements (motor tics) and vocalizations (phonic tics) that develop in childhood or adolescence. In recent years, research on TS has progressed rapidly on several fronts. Inspired by the Fifth International Scientific Symposium on Tourette Syndrome, the articles in this special issue review advances in the phenomenology, epidemiology, genetics, pathophysiology, and treatment of TS.
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randomized trial of behavior therapy for adults with Tourette Syndrome
Archives of General Psychiatry, 2012Co-Authors: Sabine Wilhelm, Douglas W. Woods, John Piacentini, Alan L Peterson, Thilo Deckersbach, Denis G Sukhodolsky, Susanna Chang, Haibei Liu, James Dziura, John T. WalkupAbstract:Context Tics in Tourette Syndrome begin in childhood, peak in early adolescence, and often decrease by early adulthood. However, some adult patients continue to have impairing tics. Medications for tics are often effective but can cause adverse effects. Behavior therapy may offer an alternative but has not been examined in a large-scale controlled trial in adults. Objective To test the efficacy of a comprehensive behavioral intervention for tics in adults with Tourette Syndrome of at least moderate severity. Design A randomized controlled trial with posttreatment evaluations at 3 and 6 months for positive responders. Setting Three outpatient research clinics. Patients Patients (N = 122; 78 males; age range, 16-69 years) with Tourette Syndrome or chronic tic disorder were recruited between December 27, 2005, and May 21, 2009. Interventions Patients received 8 sessions of comprehensive behavioral intervention for tics or 8 sessions of supportive treatment for 10 weeks. Patients with a positive response were given 3 monthly booster sessions. Main Outcome Measures Total tic score on the Yale Global Tic Severity Scale and the Clinical Global Impression–Improvement scale rated by a clinician masked to treatment assignment. Results Behavior therapy was associated with a significantly greater mean (SD) decrease on the Yale Global Tic Severity Scale (24.0 [6.47] to 17.8 [7.32]) from baseline to end point compared with the control treatment (21.8 [6.59] to 19.3 [7.40]) (P Conclusion Comprehensive behavior therapy is a safe and effective intervention for adults with Tourette Syndrome. Trial Registration clinicaltrials.gov Identifier: NCT00231985
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Treating Tourette Syndrome and Tic Disorders: A Guide for Practitioners
2007Co-Authors: Douglas W. Woods, John Piacentini, John T. WalkupAbstract:Woods, Piacentini, Walkup, Introduction to Clinical Management of Tourette Syndrome. Part I: Understanding Tourette Syndrome. Piacentini, Pearlman, Peris, Characteristics of Tourette Syndrome. Woods, Piacentini, Himle, Assessment of Tic Disorders. Scahill, Sukhodolsky, King, Assessment of Co-occurring Psychiatric Conditions in Tic Disorders. Singer, Leary, Reimschisel, Genetic and Neurobiological Bases for Tourette Syndrome. Chang, Neurocognitive Factors in Tourette Syndrome. Part II: Clinical Management of Symptoms and Associated Conditions. Harrison, Schneider, Walkup, Medical Management of Tourette Syndrome and Co-occurring Conditions. Peterson, Psychological Management of Tics and Intentional Repetitive Behaviors Associated with Tourette Syndrome. Buhlmann, Deckersbach, Cook, Wilhelm, Psychological Management of Comorbid Internalizing Disorders in Persons with Tourette Syndrome. Sukhodolsky, Scahill, Disruptive Behavior in Persons with Tourette Syndrome: Phenomenology, Assessment, and Treatment. Part III: Clinical Management of Secondary Problems. Ginsburg, Kingery, Management of Family Issues in Children with Tourette Syndrome. Kepley, Conners, Management of Learning and School Difficulties in Children with Tourette Syndrome. Woods, Marcks, Flessner, Management of Social and Occupational Difficulties in Persons with Tourette Syndrome.
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Brief review of habit reversal training for Tourette Syndrome.
Journal of child neurology, 2006Co-Authors: Michael B. Himle, Douglas W. Woods, John Piacentini, John T. WalkupAbstract:It is well established that Tourette Syndrome has a neurobiologic origin. Although pharmacotherapy is the most commonly prescribed intervention, there is considerable evidence to support the use of behavior therapy, specifically habit reversal training, as an alternative or adjunct treatment for some individuals with Tourette Syndrome. Unfortunately, many professionals are unfamiliar with habit reversal training. The purpose of this review is to provide readers with a brief review of empiric studies on habit reversal training, update readers on the current state and future of behavior therapy for Tourette Syndrome, and provide resources for those readers interested in additional information.