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Kenneth E. Lamb - One of the best experts on this subject based on the ideXlab platform.
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Correlations among Tracheal dimensions, Tracheal stent dimensions, and major complications after endoluminal stenting of Tracheal Collapse syndrome in dogs.
Journal of veterinary internal medicine, 2019Co-Authors: Nathaniel P Violette, Chick Weisse, Allyson C. Berent, Kenneth E. LambAbstract:Background Endoluminal Tracheal stenting can relieve signs associated with Tracheal Collapse syndrome (TCS) in dogs, but major complications can result. Objective To identify associations among Tracheal dimensions, stent dimensions, and subsequent complications requiring additional stent placement after endoluminal stenting for TCS. Animals Fifty-two dogs from the hospital population. Methods Medical records of dogs that received an endoluminal self-expanding Tracheal stent for TCS by the interventional radiology service between 2009 and 2014 were reviewed for relevant data. Signalment and clinical details, including Tracheal Collapse type, Tracheal measurements, nominal stent dimensions, follow-up evaluation times, and stent complications, were recorded. Results Fifty-two dogs that received an endoluminal stent for TCS met the inclusion criteria. Major complications included stent fracture (13/52; 25%), obstructive tissue ingrowth (10/52; 19%), and progressive Tracheal Collapse (6/52; 12%). Natural Tracheal taper (P = .04) and more stent diameter oversizing (P = .04) in the intrathoracic (IT) trachea were associated with caudodorsal stent fracture. Only stents with a 14-mm nominal diameter fractured. Progressive Tracheal Collapse was associated with smaller maximum Tracheal diameters (P = .02). The majority of dogs with obstructive tissue ingrowth (7/10; 70%; P = .30) and all dogs with thoracic inlet fractures (3/3; 100%) had Tracheal malformations. Conclusions and clinical importance A higher taper in Tracheal diameter may lead to increased risk of fracture in the IT location. Dogs with Tracheal malformations may have higher risk for thoracic inlet fracture and development of obstructive tissue ingrowth. Clinicians should be aware of the possible risk factors for Tracheal stent complications.
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Short-, intermediate-, and long-term results for endoluminal stent placement in dogs with Tracheal Collapse
Journal of the American Veterinary Medical Association, 2019Co-Authors: Chick Weisse, Nathaniel P Violette, Allyson C. Berent, Renee Mcdougall, Kenneth E. LambAbstract:OBJECTIVE To evaluate outcomes following endoluminal stent placement for treatment of Tracheal Collapse (TC) in dogs. DESIGN Retrospective case series with nested observational study. ANIMALS 75 dogs that underwent endoluminal placement of a self-expanding metallic stent to treat TC between September 2009 and August 2015. PROCEDURES Medical records were reviewed to collect data on dog characteristics, clinical signs, TC type, diagnostic test results, peri- and postoperative complications, and outcomes. Complication rates and survival times and rates were compared between various groups. RESULTS The 75 dogs received 119 stents (56% [42/75] received 1 stent and 44% [33/75] received ≥ 2 stents). Thirty-eight (51%) dogs had a malformation type of TC, and 37 (49%) had the traditional type. Ninety-three percent (70/75) of dogs survived to hospital discharge. Median survival time was 1,005 days. Improvement in goose-honking or raspy breathing (89% [42/47]) and dyspnea (84% [43/51]) was reported at final follow-up examination. Major complications requiring additional stent placement procedures occurred in 47% (33/70) of dogs over the follow-up period; stent fracture and tissue ingrowth were the most common types. Male dogs and younger dogs had a significantly longer survival time than other dogs. Mainstem bronchial Collapse at the time of stent placement had no significant association with outcome. CONCLUSIONS AND CLINICAL RELEVANCE Endoluminal stent placement provided a high survival rate for dogs with TC, even those with severe clinical signs. This information, as well as the information on potential complications, should be useful for advising owners of affected dogs.
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Immediate, Short-, and Long-Term Changes in Tracheal Stent Diameter, Length, and Positioning After Placement in Dogs With Tracheal Collapse Syndrome
Journal of veterinary internal medicine, 2018Co-Authors: Matthew Raske, Chick Weisse, Allyson C. Berent, Renee Mcdougall, Kenneth E. LambAbstract:Background Intraluminal Tracheal stenting is a minimally invasive procedure shown to have variable degrees of success in managing clinical signs associated with Tracheal Collapse syndrome (CTCS) in dogs. Objectives Identify immediate post-stent changes in Tracheal diameter, determine the extent of stent migration, and stent shortening after stent placement in the immediate-, short-, and long-term periods, and evaluate inter-observer reliability of radiographic measurements. Animals Fifty client-owned dogs. Methods Retrospective study in which medical records were reviewed in dogs with CTCS treated with an intraluminal Tracheal stent. Data collected included signalment, location, and type of Collapse, stent diameter and length, and post-stent placement radiographic follow-up times. Radiographs were used to obtain pre-stent Tracheal measurements and post-stent placement measurements. Results Immediate mean percentage change was 5.14%, 5.49%, and 21.64% for cervical, thoracic inlet, and intra-thoracic Tracheal diameters, respectively. Ultimate mean follow-up time was 446 days, with mean percentage change of 2.55%, 15.09%, and 8.65% for cervical, thoracic inlet, and intra-thoracic Tracheal diameters, respectively. Initial mean stent length was 26.72% higher than nominal length and ultimate long-term Tracheal mean stent shortening was only 9.90%. No significant stent migration was identified in the immediate, short-, or long-term periods. Good inter-observer agreement of radiographic measurements was found among observers of variable experience level. Conclusions and clinical importance Use of an intraluminal Tracheal stent for CTCS is associated with minimal stent shortening with no clinically relevant stent migration after fluoroscopic placement. Precise stent sizing and placement techniques likely play important roles in avoiding these reported complications.
Chick Weisse - One of the best experts on this subject based on the ideXlab platform.
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Comparison of short-, intermediate-, and long-term results between dogs with Tracheal Collapse that underwent multimodal medical management alone and those that underwent Tracheal endoluminal stent placement.
Journal of the American Veterinary Medical Association, 2021Co-Authors: Michael Congiusta, Chick Weisse, Allyson C. Berent, Erik TozierAbstract:OBJECTIVE To compare short-, intermediate-, and long-term results between dogs with Tracheal Collapse (TC) that received multimodal medical management only and those that underwent Tracheal endolum...
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Bacterial infection before and after stent placement in dogs with Tracheal Collapse syndrome.
Journal of veterinary internal medicine, 2020Co-Authors: Sylvia Lesnikowski, Chick Weisse, Allyson C. Berent, Alexandre Le Roux, Erik TozierAbstract:BACKGROUND: Dogs with Tracheal stents often have positive airway bacterial cultures. The pathogenicity of these organisms and risk factors for infection have not been investigated. OBJECTIVE: Describe bacterial infection in dogs with Tracheal Collapse before and after Tracheal stent placement. ANIMALS: Fifty‐three client‐owned dogs. METHODS: Retrospective review of medical records of dogs receiving Tracheal stents with thoracic radiographs, tracheoscopy, and endoTracheal lavage. RESULTS: There was no difference between the overall prevalence of dogs with positive bacterial cultures before (31/38; 82%) or after stent placement (24/31; 77%) (P = .67). An increased number of geriatric (17/28; 61%) and traditional‐type Collapse (TTC) (16/26; 62%) dogs had positive pathogenic airway infections before stent placement, compared to young (8/25; 32%; P = .04) and malformation‐type Collapse (MTC) dogs (9/27; 33%; P = .04). After Tracheal stent placement, geriatric dogs had a 52% reduction in pathogenic bacteria infection frequency (P = .02) and dogs with TTC had a 56% reduction in pathogenic bacteria infection frequency (P = .01). Significant risk factors for pathogenic infection included a history of pneumonia (OR = 3.6; 95% CI, 0.28‐43.36) and cardiac disease (OR = 1.25; 95% CI, 0.16‐9.92) in geriatric dogs, and hepatomegaly in young dogs (OR = 1.5; 95% CI, 0.12‐19.44). CONCLUSIONS AND CLINICAL IMPORTANCE: Tracheal stent placement does not increase the overall rate of pathogenic bacterial infection in dogs with Tracheal Collapse and can decrease the rate of subsequent pathogenic infections in geriatric dogs and dogs with TTC that require Tracheal stenting. Airway culture and cytology should be performed in all dogs undergoing Tracheal stent placement.
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Correlations among Tracheal dimensions, Tracheal stent dimensions, and major complications after endoluminal stenting of Tracheal Collapse syndrome in dogs.
Journal of veterinary internal medicine, 2019Co-Authors: Nathaniel P Violette, Chick Weisse, Allyson C. Berent, Kenneth E. LambAbstract:Background Endoluminal Tracheal stenting can relieve signs associated with Tracheal Collapse syndrome (TCS) in dogs, but major complications can result. Objective To identify associations among Tracheal dimensions, stent dimensions, and subsequent complications requiring additional stent placement after endoluminal stenting for TCS. Animals Fifty-two dogs from the hospital population. Methods Medical records of dogs that received an endoluminal self-expanding Tracheal stent for TCS by the interventional radiology service between 2009 and 2014 were reviewed for relevant data. Signalment and clinical details, including Tracheal Collapse type, Tracheal measurements, nominal stent dimensions, follow-up evaluation times, and stent complications, were recorded. Results Fifty-two dogs that received an endoluminal stent for TCS met the inclusion criteria. Major complications included stent fracture (13/52; 25%), obstructive tissue ingrowth (10/52; 19%), and progressive Tracheal Collapse (6/52; 12%). Natural Tracheal taper (P = .04) and more stent diameter oversizing (P = .04) in the intrathoracic (IT) trachea were associated with caudodorsal stent fracture. Only stents with a 14-mm nominal diameter fractured. Progressive Tracheal Collapse was associated with smaller maximum Tracheal diameters (P = .02). The majority of dogs with obstructive tissue ingrowth (7/10; 70%; P = .30) and all dogs with thoracic inlet fractures (3/3; 100%) had Tracheal malformations. Conclusions and clinical importance A higher taper in Tracheal diameter may lead to increased risk of fracture in the IT location. Dogs with Tracheal malformations may have higher risk for thoracic inlet fracture and development of obstructive tissue ingrowth. Clinicians should be aware of the possible risk factors for Tracheal stent complications.
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Short-, intermediate-, and long-term results for endoluminal stent placement in dogs with Tracheal Collapse
Journal of the American Veterinary Medical Association, 2019Co-Authors: Chick Weisse, Nathaniel P Violette, Allyson C. Berent, Renee Mcdougall, Kenneth E. LambAbstract:OBJECTIVE To evaluate outcomes following endoluminal stent placement for treatment of Tracheal Collapse (TC) in dogs. DESIGN Retrospective case series with nested observational study. ANIMALS 75 dogs that underwent endoluminal placement of a self-expanding metallic stent to treat TC between September 2009 and August 2015. PROCEDURES Medical records were reviewed to collect data on dog characteristics, clinical signs, TC type, diagnostic test results, peri- and postoperative complications, and outcomes. Complication rates and survival times and rates were compared between various groups. RESULTS The 75 dogs received 119 stents (56% [42/75] received 1 stent and 44% [33/75] received ≥ 2 stents). Thirty-eight (51%) dogs had a malformation type of TC, and 37 (49%) had the traditional type. Ninety-three percent (70/75) of dogs survived to hospital discharge. Median survival time was 1,005 days. Improvement in goose-honking or raspy breathing (89% [42/47]) and dyspnea (84% [43/51]) was reported at final follow-up examination. Major complications requiring additional stent placement procedures occurred in 47% (33/70) of dogs over the follow-up period; stent fracture and tissue ingrowth were the most common types. Male dogs and younger dogs had a significantly longer survival time than other dogs. Mainstem bronchial Collapse at the time of stent placement had no significant association with outcome. CONCLUSIONS AND CLINICAL RELEVANCE Endoluminal stent placement provided a high survival rate for dogs with TC, even those with severe clinical signs. This information, as well as the information on potential complications, should be useful for advising owners of affected dogs.
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Immediate, Short-, and Long-Term Changes in Tracheal Stent Diameter, Length, and Positioning After Placement in Dogs With Tracheal Collapse Syndrome
Journal of veterinary internal medicine, 2018Co-Authors: Matthew Raske, Chick Weisse, Allyson C. Berent, Renee Mcdougall, Kenneth E. LambAbstract:Background Intraluminal Tracheal stenting is a minimally invasive procedure shown to have variable degrees of success in managing clinical signs associated with Tracheal Collapse syndrome (CTCS) in dogs. Objectives Identify immediate post-stent changes in Tracheal diameter, determine the extent of stent migration, and stent shortening after stent placement in the immediate-, short-, and long-term periods, and evaluate inter-observer reliability of radiographic measurements. Animals Fifty client-owned dogs. Methods Retrospective study in which medical records were reviewed in dogs with CTCS treated with an intraluminal Tracheal stent. Data collected included signalment, location, and type of Collapse, stent diameter and length, and post-stent placement radiographic follow-up times. Radiographs were used to obtain pre-stent Tracheal measurements and post-stent placement measurements. Results Immediate mean percentage change was 5.14%, 5.49%, and 21.64% for cervical, thoracic inlet, and intra-thoracic Tracheal diameters, respectively. Ultimate mean follow-up time was 446 days, with mean percentage change of 2.55%, 15.09%, and 8.65% for cervical, thoracic inlet, and intra-thoracic Tracheal diameters, respectively. Initial mean stent length was 26.72% higher than nominal length and ultimate long-term Tracheal mean stent shortening was only 9.90%. No significant stent migration was identified in the immediate, short-, or long-term periods. Good inter-observer agreement of radiographic measurements was found among observers of variable experience level. Conclusions and clinical importance Use of an intraluminal Tracheal stent for CTCS is associated with minimal stent shortening with no clinically relevant stent migration after fluoroscopic placement. Precise stent sizing and placement techniques likely play important roles in avoiding these reported complications.
Allyson C. Berent - One of the best experts on this subject based on the ideXlab platform.
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Comparison of short-, intermediate-, and long-term results between dogs with Tracheal Collapse that underwent multimodal medical management alone and those that underwent Tracheal endoluminal stent placement.
Journal of the American Veterinary Medical Association, 2021Co-Authors: Michael Congiusta, Chick Weisse, Allyson C. Berent, Erik TozierAbstract:OBJECTIVE To compare short-, intermediate-, and long-term results between dogs with Tracheal Collapse (TC) that received multimodal medical management only and those that underwent Tracheal endolum...
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Bacterial infection before and after stent placement in dogs with Tracheal Collapse syndrome.
Journal of veterinary internal medicine, 2020Co-Authors: Sylvia Lesnikowski, Chick Weisse, Allyson C. Berent, Alexandre Le Roux, Erik TozierAbstract:BACKGROUND: Dogs with Tracheal stents often have positive airway bacterial cultures. The pathogenicity of these organisms and risk factors for infection have not been investigated. OBJECTIVE: Describe bacterial infection in dogs with Tracheal Collapse before and after Tracheal stent placement. ANIMALS: Fifty‐three client‐owned dogs. METHODS: Retrospective review of medical records of dogs receiving Tracheal stents with thoracic radiographs, tracheoscopy, and endoTracheal lavage. RESULTS: There was no difference between the overall prevalence of dogs with positive bacterial cultures before (31/38; 82%) or after stent placement (24/31; 77%) (P = .67). An increased number of geriatric (17/28; 61%) and traditional‐type Collapse (TTC) (16/26; 62%) dogs had positive pathogenic airway infections before stent placement, compared to young (8/25; 32%; P = .04) and malformation‐type Collapse (MTC) dogs (9/27; 33%; P = .04). After Tracheal stent placement, geriatric dogs had a 52% reduction in pathogenic bacteria infection frequency (P = .02) and dogs with TTC had a 56% reduction in pathogenic bacteria infection frequency (P = .01). Significant risk factors for pathogenic infection included a history of pneumonia (OR = 3.6; 95% CI, 0.28‐43.36) and cardiac disease (OR = 1.25; 95% CI, 0.16‐9.92) in geriatric dogs, and hepatomegaly in young dogs (OR = 1.5; 95% CI, 0.12‐19.44). CONCLUSIONS AND CLINICAL IMPORTANCE: Tracheal stent placement does not increase the overall rate of pathogenic bacterial infection in dogs with Tracheal Collapse and can decrease the rate of subsequent pathogenic infections in geriatric dogs and dogs with TTC that require Tracheal stenting. Airway culture and cytology should be performed in all dogs undergoing Tracheal stent placement.
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Correlations among Tracheal dimensions, Tracheal stent dimensions, and major complications after endoluminal stenting of Tracheal Collapse syndrome in dogs.
Journal of veterinary internal medicine, 2019Co-Authors: Nathaniel P Violette, Chick Weisse, Allyson C. Berent, Kenneth E. LambAbstract:Background Endoluminal Tracheal stenting can relieve signs associated with Tracheal Collapse syndrome (TCS) in dogs, but major complications can result. Objective To identify associations among Tracheal dimensions, stent dimensions, and subsequent complications requiring additional stent placement after endoluminal stenting for TCS. Animals Fifty-two dogs from the hospital population. Methods Medical records of dogs that received an endoluminal self-expanding Tracheal stent for TCS by the interventional radiology service between 2009 and 2014 were reviewed for relevant data. Signalment and clinical details, including Tracheal Collapse type, Tracheal measurements, nominal stent dimensions, follow-up evaluation times, and stent complications, were recorded. Results Fifty-two dogs that received an endoluminal stent for TCS met the inclusion criteria. Major complications included stent fracture (13/52; 25%), obstructive tissue ingrowth (10/52; 19%), and progressive Tracheal Collapse (6/52; 12%). Natural Tracheal taper (P = .04) and more stent diameter oversizing (P = .04) in the intrathoracic (IT) trachea were associated with caudodorsal stent fracture. Only stents with a 14-mm nominal diameter fractured. Progressive Tracheal Collapse was associated with smaller maximum Tracheal diameters (P = .02). The majority of dogs with obstructive tissue ingrowth (7/10; 70%; P = .30) and all dogs with thoracic inlet fractures (3/3; 100%) had Tracheal malformations. Conclusions and clinical importance A higher taper in Tracheal diameter may lead to increased risk of fracture in the IT location. Dogs with Tracheal malformations may have higher risk for thoracic inlet fracture and development of obstructive tissue ingrowth. Clinicians should be aware of the possible risk factors for Tracheal stent complications.
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Short-, intermediate-, and long-term results for endoluminal stent placement in dogs with Tracheal Collapse
Journal of the American Veterinary Medical Association, 2019Co-Authors: Chick Weisse, Nathaniel P Violette, Allyson C. Berent, Renee Mcdougall, Kenneth E. LambAbstract:OBJECTIVE To evaluate outcomes following endoluminal stent placement for treatment of Tracheal Collapse (TC) in dogs. DESIGN Retrospective case series with nested observational study. ANIMALS 75 dogs that underwent endoluminal placement of a self-expanding metallic stent to treat TC between September 2009 and August 2015. PROCEDURES Medical records were reviewed to collect data on dog characteristics, clinical signs, TC type, diagnostic test results, peri- and postoperative complications, and outcomes. Complication rates and survival times and rates were compared between various groups. RESULTS The 75 dogs received 119 stents (56% [42/75] received 1 stent and 44% [33/75] received ≥ 2 stents). Thirty-eight (51%) dogs had a malformation type of TC, and 37 (49%) had the traditional type. Ninety-three percent (70/75) of dogs survived to hospital discharge. Median survival time was 1,005 days. Improvement in goose-honking or raspy breathing (89% [42/47]) and dyspnea (84% [43/51]) was reported at final follow-up examination. Major complications requiring additional stent placement procedures occurred in 47% (33/70) of dogs over the follow-up period; stent fracture and tissue ingrowth were the most common types. Male dogs and younger dogs had a significantly longer survival time than other dogs. Mainstem bronchial Collapse at the time of stent placement had no significant association with outcome. CONCLUSIONS AND CLINICAL RELEVANCE Endoluminal stent placement provided a high survival rate for dogs with TC, even those with severe clinical signs. This information, as well as the information on potential complications, should be useful for advising owners of affected dogs.
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Immediate, Short-, and Long-Term Changes in Tracheal Stent Diameter, Length, and Positioning After Placement in Dogs With Tracheal Collapse Syndrome
Journal of veterinary internal medicine, 2018Co-Authors: Matthew Raske, Chick Weisse, Allyson C. Berent, Renee Mcdougall, Kenneth E. LambAbstract:Background Intraluminal Tracheal stenting is a minimally invasive procedure shown to have variable degrees of success in managing clinical signs associated with Tracheal Collapse syndrome (CTCS) in dogs. Objectives Identify immediate post-stent changes in Tracheal diameter, determine the extent of stent migration, and stent shortening after stent placement in the immediate-, short-, and long-term periods, and evaluate inter-observer reliability of radiographic measurements. Animals Fifty client-owned dogs. Methods Retrospective study in which medical records were reviewed in dogs with CTCS treated with an intraluminal Tracheal stent. Data collected included signalment, location, and type of Collapse, stent diameter and length, and post-stent placement radiographic follow-up times. Radiographs were used to obtain pre-stent Tracheal measurements and post-stent placement measurements. Results Immediate mean percentage change was 5.14%, 5.49%, and 21.64% for cervical, thoracic inlet, and intra-thoracic Tracheal diameters, respectively. Ultimate mean follow-up time was 446 days, with mean percentage change of 2.55%, 15.09%, and 8.65% for cervical, thoracic inlet, and intra-thoracic Tracheal diameters, respectively. Initial mean stent length was 26.72% higher than nominal length and ultimate long-term Tracheal mean stent shortening was only 9.90%. No significant stent migration was identified in the immediate, short-, or long-term periods. Good inter-observer agreement of radiographic measurements was found among observers of variable experience level. Conclusions and clinical importance Use of an intraluminal Tracheal stent for CTCS is associated with minimal stent shortening with no clinically relevant stent migration after fluoroscopic placement. Precise stent sizing and placement techniques likely play important roles in avoiding these reported complications.
D. Gioulekas - One of the best experts on this subject based on the ideXlab platform.
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tidal breathing flow volume loop analysis for the diagnosis and staging of Tracheal Collapse in dogs
Journal of Veterinary Internal Medicine, 2010Co-Authors: Dimitra Pardali, T.s. Rallis, D. Raptopoulos, K K Adamamamoraitou, D. GioulekasAbstract:Background: Tracheoscopy is generally used for the diagnosis of Tracheal Collapse (TC) in dogs; yet, it is costly, requires anesthesia, and can irritate the airway. The tidal breathing flow-volume loop (TBFVL) is a safe, quick, and noninvasive pulmonary function test currently used in humans. Hypothesis: TBFVL will differentiate dogs with TC from healthy controls and contribute to disease grading. Animals: Twenty-eight dogs with naturally occurring TC and 10 healthy controls. Methods: Cross-sectional, prospective clinical study: The 38 dogs were assigned to one of 4 groups based on tracheoscopy results: group A (n = 10, healthy controls), group B (n = 10, grade I TC), group C (n = 10, grade II TC), and group D (n = 8, grade III TC). The TBFVL measurement was performed on all dogs and loops were assessed for their shape. Forty-four TBFVL parameters were calculated. Results: Two types of TBFVL shapes were identified: Type I, representative of the 10 healthy controls, and Type II, representative of the 28 dogs with TC. Statistical analysis showed the dogs could be differentiated into healthy or affected by TC by 3 indices, TE/TI (expiratory time divided by inspiratory time), TI/TTOT (inspiratory time divided by total respiratory time), and EF75/IF75 (expiratory flow at end tidal volume plus 75% end tidal volume divided by inspiratory flow at end tidal volume plus 75% end tidal volume). The TC could also be graded as mild-moderate (grades I and II) or severe (grade III), showing a diagnostic value of 97.4%. Conclusion and Clinical Importance: TBFVL is accurate, quick, noninvasive, and safe and can contribute to the diagnosis of TC in dogs.
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Tidal Breathing Flow‐Volume Loop Analysis for the Diagnosis and Staging of Tracheal Collapse in Dogs
Journal of veterinary internal medicine, 2010Co-Authors: Dimitra Pardali, Katerina K. Adamama-moraitou, T.s. Rallis, D. Raptopoulos, D. GioulekasAbstract:Background: Tracheoscopy is generally used for the diagnosis of Tracheal Collapse (TC) in dogs; yet, it is costly, requires anesthesia, and can irritate the airway. The tidal breathing flow-volume loop (TBFVL) is a safe, quick, and noninvasive pulmonary function test currently used in humans. Hypothesis: TBFVL will differentiate dogs with TC from healthy controls and contribute to disease grading. Animals: Twenty-eight dogs with naturally occurring TC and 10 healthy controls. Methods: Cross-sectional, prospective clinical study: The 38 dogs were assigned to one of 4 groups based on tracheoscopy results: group A (n = 10, healthy controls), group B (n = 10, grade I TC), group C (n = 10, grade II TC), and group D (n = 8, grade III TC). The TBFVL measurement was performed on all dogs and loops were assessed for their shape. Forty-four TBFVL parameters were calculated. Results: Two types of TBFVL shapes were identified: Type I, representative of the 10 healthy controls, and Type II, representative of the 28 dogs with TC. Statistical analysis showed the dogs could be differentiated into healthy or affected by TC by 3 indices, TE/TI (expiratory time divided by inspiratory time), TI/TTOT (inspiratory time divided by total respiratory time), and EF75/IF75 (expiratory flow at end tidal volume plus 75% end tidal volume divided by inspiratory flow at end tidal volume plus 75% end tidal volume). The TC could also be graded as mild-moderate (grades I and II) or severe (grade III), showing a diagnostic value of 97.4%. Conclusion and Clinical Importance: TBFVL is accurate, quick, noninvasive, and safe and can contribute to the diagnosis of TC in dogs.
Natali Bauer - One of the best experts on this subject based on the ideXlab platform.
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Liver disease in dogs with Tracheal Collapse.
Journal of veterinary internal medicine, 2006Co-Authors: Natali Bauer, Matthias Schneider, Reto Neiger, Andreas MoritzAbstract:Background Hepatopathy in dogs with chronic respiratory diseases is poorly recognized. The aim of this study was to evaluate liver parameters alanine transferase, alkaline phosphatase, and glutamate dehydrogenase, as well as basal and stimulated bile acid concentration, in dogs with Tracheal Collapse. Hypothesis Dogs with Tracheal Collapse have hepatopathy. Animals 26 dogs with Tracheal Collapse. Materials and methods Gall bladder contraction was stimulated by intramuscular injection of a synthetic cholecystokinin analogue (ceruletide). Twelve healthy Beagle dogs and 30 dogs of various breeds investigated previously without evidence of hepatic, gastrointestinal, or respiratory diseases served as control. Amelioration of liver variables was assessed after stent implantation. Results Twelve of 26 (46%) dogs had increased serum activity of 2 or more liver enzymes. Serum basal bile acid concentrations were high in 24 of 26 dogs. Twenty- and 40-minute stimulated bile acids were significantly higher in dogs with Tracheal Collapse (64.2 +130.0/-43.0 micromol/L and 82.6 +164.0/-57.1 micromol/L) compared to the control dogs (7.0 +/- 3.6 micromol/L and 6.4 +/- 3.5 micromol/L). All twelve dogs reevaluated after a median of 58 days (48-219 days) had a normal breathing pattern and significantly decreased 20 and 40 minutes stimulated bile acids (50.0 +92.7/-32.8 micromol/L, 52.8 +97.6/-34.3 micromol/L; P = .0043), whereas plasma liver enzyme activities were not significantly influenced. Conclusion and clinical importance There was a significant hepatic dysfunction in the majority of dogs with a Tracheal Collapse. Liver function should be routinely assessed in dogs with severe respiratory disease.
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Management of Advanced Tracheal Collapse in Dogs Using Intraluminal Self‐Expanding Biliary Wallstents
Journal of veterinary internal medicine, 2004Co-Authors: Andreas Moritz, Matthias Schneider, Natali BauerAbstract:Twenty-four client-owned dogs with Tracheal Collapse refractory to conventional treatment underwent management with an intraluminal self-expanding stainless-steel endoprosthesis (Wallstent). Initial improvement of clinical signs was observed in 95.8% of the dogs. Two dogs (8.3%) died within a median interval of 6 days after stent implantation due to incorrect placement and size of the stent and emphysema, respectively. A dry cough occurred temporarily in most of the patients. One dog each (4.1%) suffered mild transient Tracheal hemorrhage and pneumomediastinum. The results showed that the initial survival rate of intraluminal stabilization was comparable with surgical implantation of extraTracheal prostheses. Clinical reevaluation was performed in 18 dogs within a median interval of 68 days after treatment. Of the dogs treated, 30.4% were reported to be asymptomatic after stent implantation, 60.9% improved markedly, and 4.3% remained symptomatic. In all patients undergoing endoscopy, the Wallstents were almost completely covered with Tracheal epithelium. A median shortening of 27.3% of the endoprosthesis within a median interval of 175 days after stent implantation in 15 of 18 dogs was noted. The shortening was associated with clinical signs in 2 patients. In 5 dogs, steroid-responsive granuloma formation resulted in a severe reduction of the Tracheal lumen in 3 patients. The results suggest that implantation of Wallstents was minimally invasive and provided stabilization of Collapsed thoracic Tracheal portions in addition to the cervical part of the trachea. This minimally invasive method for the management of severe Tracheal Collapse therefore provides an attractive alternative to surgery.
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management of advanced Tracheal Collapse in dogs using intraluminal self expanding biliary wallstents
Journal of Veterinary Internal Medicine, 2004Co-Authors: Andreas Moritz, Matthias Schneider, Natali BauerAbstract:Twenty-four client-owned dogs with Tracheal Collapse refractory to conventional treatment underwent management with an intraluminal self-expanding stainless-steel endoprosthesis (Wallstent). Initial improvement of clinical signs was observed in 95.8% of the dogs. Two dogs (8.3%) died within a median interval of 6 days after stent implantation due to incorrect placement and size of the stent and emphysema, respectively. A dry cough occurred temporarily in most of the patients. One dog each (4.1%) suffered mild transient Tracheal hemorrhage and pneumomediastinum. The results showed that the initial survival rate of intraluminal stabilization was comparable with surgical implantation of extraTracheal prostheses. Clinical reevaluation was performed in 18 dogs within a median interval of 68 days after treatment. Of the dogs treated, 30.4% were reported to be asymptomatic after stent implantation, 60.9% improved markedly, and 4.3% remained symptomatic. In all patients undergoing endoscopy, the Wallstents were almost completely covered with Tracheal epithelium. A median shortening of 27.3% of the endoprosthesis within a median interval of 175 days after stent implantation in 15 of 18 dogs was noted. The shortening was associated with clinical signs in 2 patients. In 5 dogs, steroid-responsive granuloma formation resulted in a severe reduction of the Tracheal lumen in 3 patients. The results suggest that implantation of Wallstents was minimally invasive and provided stabilization of Collapsed thoracic Tracheal portions in addition to the cervical part of the trachea. This minimally invasive method for the management of severe Tracheal Collapse therefore provides an attractive alternative to surgery.
