The Experts below are selected from a list of 279 Experts worldwide ranked by ideXlab platform
D. Gioulekas - One of the best experts on this subject based on the ideXlab platform.
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tidal breathing flow volume loop analysis for the diagnosis and staging of tracheal collapse in dogs
Journal of Veterinary Internal Medicine, 2010Co-Authors: Dimitra Pardali, T.s. Rallis, D. Raptopoulos, K K Adamamamoraitou, D. GioulekasAbstract:Background: Tracheoscopy is generally used for the diagnosis of tracheal collapse (TC) in dogs; yet, it is costly, requires anesthesia, and can irritate the airway. The tidal breathing flow-volume loop (TBFVL) is a safe, quick, and noninvasive pulmonary function test currently used in humans. Hypothesis: TBFVL will differentiate dogs with TC from healthy controls and contribute to disease grading. Animals: Twenty-eight dogs with naturally occurring TC and 10 healthy controls. Methods: Cross-sectional, prospective clinical study: The 38 dogs were assigned to one of 4 groups based on Tracheoscopy results: group A (n = 10, healthy controls), group B (n = 10, grade I TC), group C (n = 10, grade II TC), and group D (n = 8, grade III TC). The TBFVL measurement was performed on all dogs and loops were assessed for their shape. Forty-four TBFVL parameters were calculated. Results: Two types of TBFVL shapes were identified: Type I, representative of the 10 healthy controls, and Type II, representative of the 28 dogs with TC. Statistical analysis showed the dogs could be differentiated into healthy or affected by TC by 3 indices, TE/TI (expiratory time divided by inspiratory time), TI/TTOT (inspiratory time divided by total respiratory time), and EF75/IF75 (expiratory flow at end tidal volume plus 75% end tidal volume divided by inspiratory flow at end tidal volume plus 75% end tidal volume). The TC could also be graded as mild-moderate (grades I and II) or severe (grade III), showing a diagnostic value of 97.4%. Conclusion and Clinical Importance: TBFVL is accurate, quick, noninvasive, and safe and can contribute to the diagnosis of TC in dogs.
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Tidal Breathing Flow‐Volume Loop Analysis for the Diagnosis and Staging of Tracheal Collapse in Dogs
Journal of veterinary internal medicine, 2010Co-Authors: Dimitra Pardali, Katerina K. Adamama-moraitou, T.s. Rallis, D. Raptopoulos, D. GioulekasAbstract:Background: Tracheoscopy is generally used for the diagnosis of tracheal collapse (TC) in dogs; yet, it is costly, requires anesthesia, and can irritate the airway. The tidal breathing flow-volume loop (TBFVL) is a safe, quick, and noninvasive pulmonary function test currently used in humans. Hypothesis: TBFVL will differentiate dogs with TC from healthy controls and contribute to disease grading. Animals: Twenty-eight dogs with naturally occurring TC and 10 healthy controls. Methods: Cross-sectional, prospective clinical study: The 38 dogs were assigned to one of 4 groups based on Tracheoscopy results: group A (n = 10, healthy controls), group B (n = 10, grade I TC), group C (n = 10, grade II TC), and group D (n = 8, grade III TC). The TBFVL measurement was performed on all dogs and loops were assessed for their shape. Forty-four TBFVL parameters were calculated. Results: Two types of TBFVL shapes were identified: Type I, representative of the 10 healthy controls, and Type II, representative of the 28 dogs with TC. Statistical analysis showed the dogs could be differentiated into healthy or affected by TC by 3 indices, TE/TI (expiratory time divided by inspiratory time), TI/TTOT (inspiratory time divided by total respiratory time), and EF75/IF75 (expiratory flow at end tidal volume plus 75% end tidal volume divided by inspiratory flow at end tidal volume plus 75% end tidal volume). The TC could also be graded as mild-moderate (grades I and II) or severe (grade III), showing a diagnostic value of 97.4%. Conclusion and Clinical Importance: TBFVL is accurate, quick, noninvasive, and safe and can contribute to the diagnosis of TC in dogs.
Saad Nseir - One of the best experts on this subject based on the ideXlab platform.
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Intubation-related tracheal ischemic lesions: incidence, risk factors, and outcome
Intensive Care Medicine, 2013Co-Authors: Lylia Touat, Clément Fournier, Philippe Ramon, Julia Salleron, Alain Durocher, Saad NseirAbstract:Purpose To determine incidence, risk factors and outcome of tracheal ischemic lesions related to intubation. Methods Planned post hoc analysis using patients from a previous randomized controlled study. Fiberoptic Tracheoscopy was performed during the 24 h following extubation. In patients with >2 ischemic lesions, ulcer or tracheal rupture, fiberoptic Tracheoscopy was repeated 2 weeks after the last extubation. Tracheal ischemic lesions were predefined based on a quantitative score. Results Ninety-six adult patients were included in this study. Eighty (83 %) patients had at least one tracheal ischemic lesion. Thirty-seven (38 %) patients had a tracheal ischemia score > median score (5; IQ 1, 7). The most common tracheal ischemic lesion was ischemia (68 %), followed by hyperemia (54 %), ulcer (10 %), and tracheal rupture (1 %). Univariate analysis identified duration of neuromuscular-blocking agent use, overinflation of tracheal cuff (>30 cmH_2O), percentage of P _cuff determination >30 cmH_2O, duration of assist-control ventilation, and plateau pressure as risk factors for having a tracheal ischemia score >5. Duration of assist-control mechanical ventilation was the only factor independently associated with tracheal ischemia score >5 [OR (95 % CI) 1.10 per hour (1.02–1.20)]. A fiberoptic Tracheoscopy was performed 2 weeks after extubation in 22 patients. This examination was normal in all patients, except the one with tracheal rupture who had marked improvement. Conclusion Tracheal ischemic lesions are common in intubated, critically ill patients. Duration of assist-control mechanical ventilation through a tracheal tube is the only independent risk factor. These lesions healed in the majority of patients 2 weeks after extubation.
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Intubation-related tracheal ischemic lesions: incidence, risk factors, and outcome
Intensive care medicine, 2012Co-Authors: Lylia Touat, Clément Fournier, Philippe Ramon, Julia Salleron, Alain Durocher, Saad NseirAbstract:To determine incidence, risk factors and outcome of tracheal ischemic lesions related to intubation. Planned post hoc analysis using patients from a previous randomized controlled study. Fiberoptic Tracheoscopy was performed during the 24 h following extubation. In patients with >2 ischemic lesions, ulcer or tracheal rupture, fiberoptic Tracheoscopy was repeated 2 weeks after the last extubation. Tracheal ischemic lesions were predefined based on a quantitative score. Ninety-six adult patients were included in this study. Eighty (83 %) patients had at least one tracheal ischemic lesion. Thirty-seven (38 %) patients had a tracheal ischemia score > median score (5; IQ 1, 7). The most common tracheal ischemic lesion was ischemia (68 %), followed by hyperemia (54 %), ulcer (10 %), and tracheal rupture (1 %). Univariate analysis identified duration of neuromuscular-blocking agent use, overinflation of tracheal cuff (>30 cmH2O), percentage of P cuff determination >30 cmH2O, duration of assist-control ventilation, and plateau pressure as risk factors for having a tracheal ischemia score >5. Duration of assist-control mechanical ventilation was the only factor independently associated with tracheal ischemia score >5 [OR (95 % CI) 1.10 per hour (1.02–1.20)]. A fiberoptic Tracheoscopy was performed 2 weeks after extubation in 22 patients. This examination was normal in all patients, except the one with tracheal rupture who had marked improvement. Tracheal ischemic lesions are common in intubated, critically ill patients. Duration of assist-control mechanical ventilation through a tracheal tube is the only independent risk factor. These lesions healed in the majority of patients 2 weeks after extubation.
Dimitra Pardali - One of the best experts on this subject based on the ideXlab platform.
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tidal breathing flow volume loop analysis for the diagnosis and staging of tracheal collapse in dogs
Journal of Veterinary Internal Medicine, 2010Co-Authors: Dimitra Pardali, T.s. Rallis, D. Raptopoulos, K K Adamamamoraitou, D. GioulekasAbstract:Background: Tracheoscopy is generally used for the diagnosis of tracheal collapse (TC) in dogs; yet, it is costly, requires anesthesia, and can irritate the airway. The tidal breathing flow-volume loop (TBFVL) is a safe, quick, and noninvasive pulmonary function test currently used in humans. Hypothesis: TBFVL will differentiate dogs with TC from healthy controls and contribute to disease grading. Animals: Twenty-eight dogs with naturally occurring TC and 10 healthy controls. Methods: Cross-sectional, prospective clinical study: The 38 dogs were assigned to one of 4 groups based on Tracheoscopy results: group A (n = 10, healthy controls), group B (n = 10, grade I TC), group C (n = 10, grade II TC), and group D (n = 8, grade III TC). The TBFVL measurement was performed on all dogs and loops were assessed for their shape. Forty-four TBFVL parameters were calculated. Results: Two types of TBFVL shapes were identified: Type I, representative of the 10 healthy controls, and Type II, representative of the 28 dogs with TC. Statistical analysis showed the dogs could be differentiated into healthy or affected by TC by 3 indices, TE/TI (expiratory time divided by inspiratory time), TI/TTOT (inspiratory time divided by total respiratory time), and EF75/IF75 (expiratory flow at end tidal volume plus 75% end tidal volume divided by inspiratory flow at end tidal volume plus 75% end tidal volume). The TC could also be graded as mild-moderate (grades I and II) or severe (grade III), showing a diagnostic value of 97.4%. Conclusion and Clinical Importance: TBFVL is accurate, quick, noninvasive, and safe and can contribute to the diagnosis of TC in dogs.
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Tidal Breathing Flow‐Volume Loop Analysis for the Diagnosis and Staging of Tracheal Collapse in Dogs
Journal of veterinary internal medicine, 2010Co-Authors: Dimitra Pardali, Katerina K. Adamama-moraitou, T.s. Rallis, D. Raptopoulos, D. GioulekasAbstract:Background: Tracheoscopy is generally used for the diagnosis of tracheal collapse (TC) in dogs; yet, it is costly, requires anesthesia, and can irritate the airway. The tidal breathing flow-volume loop (TBFVL) is a safe, quick, and noninvasive pulmonary function test currently used in humans. Hypothesis: TBFVL will differentiate dogs with TC from healthy controls and contribute to disease grading. Animals: Twenty-eight dogs with naturally occurring TC and 10 healthy controls. Methods: Cross-sectional, prospective clinical study: The 38 dogs were assigned to one of 4 groups based on Tracheoscopy results: group A (n = 10, healthy controls), group B (n = 10, grade I TC), group C (n = 10, grade II TC), and group D (n = 8, grade III TC). The TBFVL measurement was performed on all dogs and loops were assessed for their shape. Forty-four TBFVL parameters were calculated. Results: Two types of TBFVL shapes were identified: Type I, representative of the 10 healthy controls, and Type II, representative of the 28 dogs with TC. Statistical analysis showed the dogs could be differentiated into healthy or affected by TC by 3 indices, TE/TI (expiratory time divided by inspiratory time), TI/TTOT (inspiratory time divided by total respiratory time), and EF75/IF75 (expiratory flow at end tidal volume plus 75% end tidal volume divided by inspiratory flow at end tidal volume plus 75% end tidal volume). The TC could also be graded as mild-moderate (grades I and II) or severe (grade III), showing a diagnostic value of 97.4%. Conclusion and Clinical Importance: TBFVL is accurate, quick, noninvasive, and safe and can contribute to the diagnosis of TC in dogs.
Lylia Touat - One of the best experts on this subject based on the ideXlab platform.
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Intubation-related tracheal ischemic lesions: incidence, risk factors, and outcome
Intensive Care Medicine, 2013Co-Authors: Lylia Touat, Clément Fournier, Philippe Ramon, Julia Salleron, Alain Durocher, Saad NseirAbstract:Purpose To determine incidence, risk factors and outcome of tracheal ischemic lesions related to intubation. Methods Planned post hoc analysis using patients from a previous randomized controlled study. Fiberoptic Tracheoscopy was performed during the 24 h following extubation. In patients with >2 ischemic lesions, ulcer or tracheal rupture, fiberoptic Tracheoscopy was repeated 2 weeks after the last extubation. Tracheal ischemic lesions were predefined based on a quantitative score. Results Ninety-six adult patients were included in this study. Eighty (83 %) patients had at least one tracheal ischemic lesion. Thirty-seven (38 %) patients had a tracheal ischemia score > median score (5; IQ 1, 7). The most common tracheal ischemic lesion was ischemia (68 %), followed by hyperemia (54 %), ulcer (10 %), and tracheal rupture (1 %). Univariate analysis identified duration of neuromuscular-blocking agent use, overinflation of tracheal cuff (>30 cmH_2O), percentage of P _cuff determination >30 cmH_2O, duration of assist-control ventilation, and plateau pressure as risk factors for having a tracheal ischemia score >5. Duration of assist-control mechanical ventilation was the only factor independently associated with tracheal ischemia score >5 [OR (95 % CI) 1.10 per hour (1.02–1.20)]. A fiberoptic Tracheoscopy was performed 2 weeks after extubation in 22 patients. This examination was normal in all patients, except the one with tracheal rupture who had marked improvement. Conclusion Tracheal ischemic lesions are common in intubated, critically ill patients. Duration of assist-control mechanical ventilation through a tracheal tube is the only independent risk factor. These lesions healed in the majority of patients 2 weeks after extubation.
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Intubation-related tracheal ischemic lesions: incidence, risk factors, and outcome
Intensive care medicine, 2012Co-Authors: Lylia Touat, Clément Fournier, Philippe Ramon, Julia Salleron, Alain Durocher, Saad NseirAbstract:To determine incidence, risk factors and outcome of tracheal ischemic lesions related to intubation. Planned post hoc analysis using patients from a previous randomized controlled study. Fiberoptic Tracheoscopy was performed during the 24 h following extubation. In patients with >2 ischemic lesions, ulcer or tracheal rupture, fiberoptic Tracheoscopy was repeated 2 weeks after the last extubation. Tracheal ischemic lesions were predefined based on a quantitative score. Ninety-six adult patients were included in this study. Eighty (83 %) patients had at least one tracheal ischemic lesion. Thirty-seven (38 %) patients had a tracheal ischemia score > median score (5; IQ 1, 7). The most common tracheal ischemic lesion was ischemia (68 %), followed by hyperemia (54 %), ulcer (10 %), and tracheal rupture (1 %). Univariate analysis identified duration of neuromuscular-blocking agent use, overinflation of tracheal cuff (>30 cmH2O), percentage of P cuff determination >30 cmH2O, duration of assist-control ventilation, and plateau pressure as risk factors for having a tracheal ischemia score >5. Duration of assist-control mechanical ventilation was the only factor independently associated with tracheal ischemia score >5 [OR (95 % CI) 1.10 per hour (1.02–1.20)]. A fiberoptic Tracheoscopy was performed 2 weeks after extubation in 22 patients. This examination was normal in all patients, except the one with tracheal rupture who had marked improvement. Tracheal ischemic lesions are common in intubated, critically ill patients. Duration of assist-control mechanical ventilation through a tracheal tube is the only independent risk factor. These lesions healed in the majority of patients 2 weeks after extubation.
D. Raptopoulos - One of the best experts on this subject based on the ideXlab platform.
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tidal breathing flow volume loop analysis for the diagnosis and staging of tracheal collapse in dogs
Journal of Veterinary Internal Medicine, 2010Co-Authors: Dimitra Pardali, T.s. Rallis, D. Raptopoulos, K K Adamamamoraitou, D. GioulekasAbstract:Background: Tracheoscopy is generally used for the diagnosis of tracheal collapse (TC) in dogs; yet, it is costly, requires anesthesia, and can irritate the airway. The tidal breathing flow-volume loop (TBFVL) is a safe, quick, and noninvasive pulmonary function test currently used in humans. Hypothesis: TBFVL will differentiate dogs with TC from healthy controls and contribute to disease grading. Animals: Twenty-eight dogs with naturally occurring TC and 10 healthy controls. Methods: Cross-sectional, prospective clinical study: The 38 dogs were assigned to one of 4 groups based on Tracheoscopy results: group A (n = 10, healthy controls), group B (n = 10, grade I TC), group C (n = 10, grade II TC), and group D (n = 8, grade III TC). The TBFVL measurement was performed on all dogs and loops were assessed for their shape. Forty-four TBFVL parameters were calculated. Results: Two types of TBFVL shapes were identified: Type I, representative of the 10 healthy controls, and Type II, representative of the 28 dogs with TC. Statistical analysis showed the dogs could be differentiated into healthy or affected by TC by 3 indices, TE/TI (expiratory time divided by inspiratory time), TI/TTOT (inspiratory time divided by total respiratory time), and EF75/IF75 (expiratory flow at end tidal volume plus 75% end tidal volume divided by inspiratory flow at end tidal volume plus 75% end tidal volume). The TC could also be graded as mild-moderate (grades I and II) or severe (grade III), showing a diagnostic value of 97.4%. Conclusion and Clinical Importance: TBFVL is accurate, quick, noninvasive, and safe and can contribute to the diagnosis of TC in dogs.
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Tidal Breathing Flow‐Volume Loop Analysis for the Diagnosis and Staging of Tracheal Collapse in Dogs
Journal of veterinary internal medicine, 2010Co-Authors: Dimitra Pardali, Katerina K. Adamama-moraitou, T.s. Rallis, D. Raptopoulos, D. GioulekasAbstract:Background: Tracheoscopy is generally used for the diagnosis of tracheal collapse (TC) in dogs; yet, it is costly, requires anesthesia, and can irritate the airway. The tidal breathing flow-volume loop (TBFVL) is a safe, quick, and noninvasive pulmonary function test currently used in humans. Hypothesis: TBFVL will differentiate dogs with TC from healthy controls and contribute to disease grading. Animals: Twenty-eight dogs with naturally occurring TC and 10 healthy controls. Methods: Cross-sectional, prospective clinical study: The 38 dogs were assigned to one of 4 groups based on Tracheoscopy results: group A (n = 10, healthy controls), group B (n = 10, grade I TC), group C (n = 10, grade II TC), and group D (n = 8, grade III TC). The TBFVL measurement was performed on all dogs and loops were assessed for their shape. Forty-four TBFVL parameters were calculated. Results: Two types of TBFVL shapes were identified: Type I, representative of the 10 healthy controls, and Type II, representative of the 28 dogs with TC. Statistical analysis showed the dogs could be differentiated into healthy or affected by TC by 3 indices, TE/TI (expiratory time divided by inspiratory time), TI/TTOT (inspiratory time divided by total respiratory time), and EF75/IF75 (expiratory flow at end tidal volume plus 75% end tidal volume divided by inspiratory flow at end tidal volume plus 75% end tidal volume). The TC could also be graded as mild-moderate (grades I and II) or severe (grade III), showing a diagnostic value of 97.4%. Conclusion and Clinical Importance: TBFVL is accurate, quick, noninvasive, and safe and can contribute to the diagnosis of TC in dogs.
