The Experts below are selected from a list of 267 Experts worldwide ranked by ideXlab platform
Michael K Brawer - One of the best experts on this subject based on the ideXlab platform.
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diagnosis of prostatic carcinoma the yield of serum prostate specific antigen digital rectal examination and Transrectal Ultrasonography
The Journal of Urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:AbstractThree tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital rectal examination and Transrectal Ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital rectal examination or Transrectal Ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus Transrectal Ultrasonography and PSA plus digital rectal examination were superior to digital rectal examination plus Transrectal Ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital rectal examination and PSA level of ...
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Diagnosis of prostatic carcinoma: the yield of serum prostate specific antigen, digital rectal examination and Transrectal Ultrasonography.
The Journal of urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:Three tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital rectal examination and Transrectal Ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital rectal examination or Transrectal Ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus Transrectal Ultrasonography and PSA plus digital rectal examination were superior to digital rectal examination plus Transrectal Ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital rectal examination and PSA level of less than 4.0 ng./ml. demonstrated carcinoma on biopsy. Of the 5 patients 4 had annual increases in PSA of 40% or greater. While hypoechoic sectors were more than twice as likely as isoechoic sectors of the prostate to contain malignancy on biopsy, nearly 37.6% of the cancers were found in isoechoic sectors. A strategy of performing biopsy of only hypoechoic sectors would have misdiagnosed 24.6% of the patients with prostate cancer. We conclude that serum PSA is the most accurate of the 3 diagnostic tests evaluated. We also recommend a systematic sextant biopsy technique.
William J Ellis - One of the best experts on this subject based on the ideXlab platform.
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Role of Transrectal Ultrasonography in prostate brachytherapy.
Journal of endourology, 2000Co-Authors: William J EllisAbstract:ABSTRACT Modern brachytherapy has been made possible by advances in ultrasound technology. This technology allows accurate determination of gland size, determination of the relation to the pubic arch, and real-time placement of the radioactive sources. A thorough familiarity with Transrectal Ultrasonography thus is required to produce high-quality implants consistently.
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diagnosis of prostatic carcinoma the yield of serum prostate specific antigen digital rectal examination and Transrectal Ultrasonography
The Journal of Urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:AbstractThree tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital rectal examination and Transrectal Ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital rectal examination or Transrectal Ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus Transrectal Ultrasonography and PSA plus digital rectal examination were superior to digital rectal examination plus Transrectal Ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital rectal examination and PSA level of ...
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Diagnosis of prostatic carcinoma: the yield of serum prostate specific antigen, digital rectal examination and Transrectal Ultrasonography.
The Journal of urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:Three tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital rectal examination and Transrectal Ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital rectal examination or Transrectal Ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus Transrectal Ultrasonography and PSA plus digital rectal examination were superior to digital rectal examination plus Transrectal Ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital rectal examination and PSA level of less than 4.0 ng./ml. demonstrated carcinoma on biopsy. Of the 5 patients 4 had annual increases in PSA of 40% or greater. While hypoechoic sectors were more than twice as likely as isoechoic sectors of the prostate to contain malignancy on biopsy, nearly 37.6% of the cancers were found in isoechoic sectors. A strategy of performing biopsy of only hypoechoic sectors would have misdiagnosed 24.6% of the patients with prostate cancer. We conclude that serum PSA is the most accurate of the 3 diagnostic tests evaluated. We also recommend a systematic sextant biopsy technique.
Steven D Preston - One of the best experts on this subject based on the ideXlab platform.
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diagnosis of prostatic carcinoma the yield of serum prostate specific antigen digital rectal examination and Transrectal Ultrasonography
The Journal of Urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:AbstractThree tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital rectal examination and Transrectal Ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital rectal examination or Transrectal Ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus Transrectal Ultrasonography and PSA plus digital rectal examination were superior to digital rectal examination plus Transrectal Ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital rectal examination and PSA level of ...
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Diagnosis of prostatic carcinoma: the yield of serum prostate specific antigen, digital rectal examination and Transrectal Ultrasonography.
The Journal of urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:Three tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital rectal examination and Transrectal Ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital rectal examination or Transrectal Ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus Transrectal Ultrasonography and PSA plus digital rectal examination were superior to digital rectal examination plus Transrectal Ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital rectal examination and PSA level of less than 4.0 ng./ml. demonstrated carcinoma on biopsy. Of the 5 patients 4 had annual increases in PSA of 40% or greater. While hypoechoic sectors were more than twice as likely as isoechoic sectors of the prostate to contain malignancy on biopsy, nearly 37.6% of the cancers were found in isoechoic sectors. A strategy of performing biopsy of only hypoechoic sectors would have misdiagnosed 24.6% of the patients with prostate cancer. We conclude that serum PSA is the most accurate of the 3 diagnostic tests evaluated. We also recommend a systematic sextant biopsy technique.
Michael P Chetner - One of the best experts on this subject based on the ideXlab platform.
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diagnosis of prostatic carcinoma the yield of serum prostate specific antigen digital rectal examination and Transrectal Ultrasonography
The Journal of Urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:AbstractThree tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital rectal examination and Transrectal Ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital rectal examination or Transrectal Ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus Transrectal Ultrasonography and PSA plus digital rectal examination were superior to digital rectal examination plus Transrectal Ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital rectal examination and PSA level of ...
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Diagnosis of prostatic carcinoma: the yield of serum prostate specific antigen, digital rectal examination and Transrectal Ultrasonography.
The Journal of urology, 1994Co-Authors: William J Ellis, Michael P Chetner, Steven D Preston, Michael K BrawerAbstract:Three tests are commonly used to diagnose prostate carcinoma to date: serum prostate specific antigen (PSA), digital rectal examination and Transrectal Ultrasonography. We evaluated these 3 tests in 1,001, 6-sector prostate needle biopsies to rule out prostate carcinoma. Of the biopsies 253 (25.3%) revealed prostate cancer. As a single test, PSA was superior to digital rectal examination or Transrectal Ultrasonography in predicting cancer in this patient population using difference of proportions tests. Receiver operating characteristic analysis also showed PSA to be the superior test. The combinations of PSA plus Transrectal Ultrasonography and PSA plus digital rectal examination were superior to digital rectal examination plus Transrectal Ultrasonography. We found cancer in 35 of 188 patients (18.6%) with intermediate PSA levels of 4.1 to 10.0 ng./ml. and normal or asymmetric nonindurated rectal examinations. Only 5 of 79 patients (6.3%) with a normal digital rectal examination and PSA level of less than 4.0 ng./ml. demonstrated carcinoma on biopsy. Of the 5 patients 4 had annual increases in PSA of 40% or greater. While hypoechoic sectors were more than twice as likely as isoechoic sectors of the prostate to contain malignancy on biopsy, nearly 37.6% of the cancers were found in isoechoic sectors. A strategy of performing biopsy of only hypoechoic sectors would have misdiagnosed 24.6% of the patients with prostate cancer. We conclude that serum PSA is the most accurate of the 3 diagnostic tests evaluated. We also recommend a systematic sextant biopsy technique.
Zhiyong Liu - One of the best experts on this subject based on the ideXlab platform.
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prospective trial comparing Transrectal Ultrasonography and transurethral seminal vesiculoscopy for persistent hematospermia
International Journal of Urology, 2012Co-Authors: Changyong Xing, Xiaomei Zhou, Lei Xin, Jingchuan Fang, Zhiyong LiuAbstract:Objective: To compare the diagnostic yield of Transrectal Ultrasonography and transurethral seminal vesiculoscopy in patients with persistent hematospermia, and to determine the advantages and disadvantages of both modalities. Methods: We prospectively enrolled 106 patients with persistent hematospermia of mean duration 20.5 months. All patients were evaluated by both Transrectal Ultrasonography and transurethral seminal vesiculoscopy after excluding definite etiological lesions beyond the reproductive duct system. The diagnostic yield and other technical parameters of both modalities were compared. Results: Final diagnoses were made in 93 patients (87.7%), with Transrectal Ultrasonography and transurethral seminal vesiculoscopy showing overall diagnostic yields of 45.3% and 74.5%, respectively (P < 0.001). The diagnostic yield of combining Transrectal Ultrasonography and transurethral seminal vesiculoscopy was significantly higher than that of each modality alone (both P < 0.001). Of the 114 findings of diagnostic value, the most frequent was calculus (47.4%, n = 54), followed by obstruction/stricture (37.7%, n = 43), cyst (8.8%, n = 10), dysplasia (3.5%, n = 4), polyp (1.8%, n = 2) and benign mass (0.9%, n = 1). Transurethral seminal vesiculoscopy showed significant superiority in detecting calculi and obstruction/stricture. Hematospermia disappeared in 95.3% (101/106) of all patients and in 97.6% (83/85) of patients receiving transurethral seminal vesiculoscopy therapy during follow up. No major adverse effects occurred during and after examination. Conclusions: The diagnostic yield of transurethral seminal vesiculoscopy for persistent hematospermia was significantly superior to that of Transrectal Ultrasonography, especially in lesions diagnosed with calculi and obstruction/stricture. Combining both modalities might provide extra benefits for patients with persistent hematospermia.
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Prospective trial comparing Transrectal Ultrasonography and transurethral seminal vesiculoscopy for persistent hematospermia.
International journal of urology : official journal of the Japanese Urological Association, 2012Co-Authors: Changyong Xing, Xiaomei Zhou, Lei Xin, Jingchuan Fang, Zhiyong LiuAbstract:Objective: To compare the diagnostic yield of Transrectal Ultrasonography and transurethral seminal vesiculoscopy in patients with persistent hematospermia, and to determine the advantages and disadvantages of both modalities. Methods: We prospectively enrolled 106 patients with persistent hematospermia of mean duration 20.5 months. All patients were evaluated by both Transrectal Ultrasonography and transurethral seminal vesiculoscopy after excluding definite etiological lesions beyond the reproductive duct system. The diagnostic yield and other technical parameters of both modalities were compared. Results: Final diagnoses were made in 93 patients (87.7%), with Transrectal Ultrasonography and transurethral seminal vesiculoscopy showing overall diagnostic yields of 45.3% and 74.5%, respectively (P
