The Experts below are selected from a list of 159 Experts worldwide ranked by ideXlab platform
Rafael Cantón - One of the best experts on this subject based on the ideXlab platform.
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Bacteriologic diagnosis of respiratory tract infection
Clinical Microbiology and Infection, 1996Co-Authors: Fernando Baquero, Maria-elena Alvarez, Rafael CantónAbstract:The use of the Gram stain for determination of the presence of bacteria in respiratory secretions is described. Success of the procedure depends on the use of fresh samples of high cellular quality. The Gram stain can be used to distinguish the presence (among other organisms) of Streptococcus pneumoniae, Haemophilus influenzae, Branhamella catarrhalis enterobacteria and Pseudomonas. This paper also discusses the use of sputum samples for bacteriologic culture and the value of bacterial counts in expectorated sputum, and describes the use of transtracheal Aspiration and Transthoracic Aspiration puncture. Finally, it considers the optimum procedures for the testing of antibiotic susceptibility of presumptive pathogens isolated from the lower respiratory tract.
Ömer Etlik - One of the best experts on this subject based on the ideXlab platform.
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mr fluoroscopy guided Transthoracic fine needle Aspiration biopsy feasibility
Radiology, 2003Co-Authors: Mehmet Emin Sakarya, Özkan Ünal, Bülent Özbay, Kürşat Uzun, Ismail Kati, Suleyman Ozen, Ömer EtlikAbstract:The purpose of this study was to evaluate the feasibility of using an open-configuration magnetic resonance (MR) imaging system with MR fluoroscopic guidance to perform percutaneous Transthoracic fine-needle Aspiration biopsy in patients with lung masses. Percutaneous Transthoracic Aspiration biopsies were performed with MR fluoroscopic guidance in 14 patients. The masses were 2–7 cm in diameter (mean, 4.1 cm). The needle was positioned by using a free-hand technique with MR fluoroscopic guidance. The needle tip reached the target lesion, and biopsy was performed. Analysis of the biopsy specimens facilitated a specific diagnosis in all patients. Pneumothorax was noted in two patients (14%) with chronic obstructive pulmonary disease. Study results showed that the described MR fluoroscopy–guided Transthoracic biopsy technique can be used safely and successfully for lung masses. MR fluoroscopy can be used to reach the target lesion easily and accurately. © RSNA, 2003
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MR Fluoroscopy–guided Transthoracic Fine-Needle Aspiration Biopsy: Feasibility
Radiology, 2003Co-Authors: Mehmet Emin Sakarya, Özkan Ünal, Bülent Özbay, Kürşat Uzun, Ismail Kati, Suleyman Ozen, Ömer EtlikAbstract:The purpose of this study was to evaluate the feasibility of using an open-configuration magnetic resonance (MR) imaging system with MR fluoroscopic guidance to perform percutaneous Transthoracic fine-needle Aspiration biopsy in patients with lung masses. Percutaneous Transthoracic Aspiration biopsies were performed with MR fluoroscopic guidance in 14 patients. The masses were 2–7 cm in diameter (mean, 4.1 cm). The needle was positioned by using a free-hand technique with MR fluoroscopic guidance. The needle tip reached the target lesion, and biopsy was performed. Analysis of the biopsy specimens facilitated a specific diagnosis in all patients. Pneumothorax was noted in two patients (14%) with chronic obstructive pulmonary disease. Study results showed that the described MR fluoroscopy–guided Transthoracic biopsy technique can be used safely and successfully for lung masses. MR fluoroscopy can be used to reach the target lesion easily and accurately. © RSNA, 2003
Xiao-liang Chen - One of the best experts on this subject based on the ideXlab platform.
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CT-guided Transthoracic needle biopsy of pulmonary lesions: comparison between the cutting needle and Aspiration needle.
The British journal of radiology, 2020Co-Authors: Zhen-guo Huang, Hongliang Sun, Cun-li Wang, Bao-xiang Gao, He Chen, Min-xing Yang, Xiao-liang ChenAbstract:OBJECTIVES To compare CT-guided Transthoracic cutting needle biopsy (TCNB) with Transthoracic Aspiration needle biopsy (TANB) for pulmonary lesions with respect to the diagnostic accuracy and complication rate. METHODS Of the 859 cases that underwent consecutive CT-guided biopsy of pulmonary lesions, 713 cases confirmed by surgical pathology or clinical follow-up were enrolled. Of these, the first consecutive 275 cases underwent TANB, and the remaining 438 received TCNB. The final diagnosis determined the accuracy of biopsy. Based on the post-biopsy CT and clinical medical records, the presence or absence of biopsy-related complications was determined. The χ2 test was used to compare the differences between TCNB and TANB in terms of diagnostic accuracy and complication rate. RESULTS Among the 713 biopsy lesions, the final diagnosis was malignant in 411 cases and benign in 302 cases. As compared to TANB, the diagnostic accuracy of TCNB (98.9% vs 93.8%, χ2 = 14.35, p < 0.01), sensitivity to malignant lesions (97.8% vs 90.6%, χ2 = 10.58, p < 0.01), negative predictive value (97.6% vs 84.8%, χ2 = 19.03, p < 0.01), and specific diagnostic rate for benign lesions (73.4% vs 57.9%, χ2 = 7.29, p < 0.01) were improved. On the other hand, a statistical difference was detected between TCNB and TANB with respect to the incidence of pneumothorax (20.6% vs 13.1%, χ2 = 6.46, p = 0.01), hemorrhage (32.2% vs 13.1%, χ2 = 33.03, p < 0.01), hemoptysis (8.2% vs 3.3%, χ2 = 6.87, p < 0.01). One patient died just several minutes after TCNB due to severe hemorrhage with hemoptysis. CONCLUSIONS Compared to TANB, CT-guided TCNB improves the diagnostic accuracy of pulmonary lesions, but complication rate increases significantly. ADVANCES IN KNOWLEDGE In general, TCNB should be recommended, especially for highly suspicious benign lesions. For patients with small lesions adjacent to vessels or vessels within the lesion, TANB should be considered.
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CT-guided Transthoracic needle biopsy of pulmonary lesions: comparison between the cutting needle and Aspiration needle
The British journal of radiology, 2020Co-Authors: Zhen-guo Huang, Hongliang Sun, Cun-li Wang, Bao-xiang Gao, He Chen, Min-xing Yang, Xiao-liang ChenAbstract:Objectives:To compare CT-guided Transthoracic cutting needle biopsy (TCNB) with Transthoracic Aspiration needle biopsy (TANB) for pulmonary lesions with respect to the diagnostic accuracy and compl...
Manuel Rubio-caballero - One of the best experts on this subject based on the ideXlab platform.
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Transthoracic needle Aspiration in the study of pulmonary infections in patients with HIV.
Chest, 1994Co-Authors: Miquel Falguera, Antoni Nogués, Agustín Ruiz-gonzález, Mercè García, Teresa Puig, Manuel Rubio-caballeroAbstract:Study objective To evaluate the safety and efficacy of Transthoracic Aspiration with an ultrathin needle in the microbiologic diagnosis of pulmonary infections in HIV-infected patients. Design Retrospective review of cases. Setting A 500-bed teaching hospital in Lleida, Spain. Patients Forty-five HIV-infected patients admitted between March 1989 and March 1993 with clinical and roentgenographic evidence of pulmonary infection and without contraindications for Transthoracic needle Aspiration (TNA). Interventions Forty-seven TNAs were performed in the emergency room (20) or during hospitalization (27). The TNA procedures were done without premedication and without fluoroscopic guidance. Specimens were processed using routine microbiologic and cytologic techniques; in addition, polymerase chain reaction (PCR) for Pneumocystis carinii was carried out since March 1992. Development of adverse effects was carefully evaluated. Results The TNA was effective in 29 (62 percent) out of 47 procedures. The diagnosis was obtained for 14 of 15 patients with P carinii pneumonia, 8 out of 14 patients with bacterial pneumonia, and 4 out of 12 patients with tuberculosis. Other pathogens recovered were Nocardia asteroides, Cryptococcus neoformans, Rhodococcus equi , and Mycobacterium avium No false-positive results were obtained. Pneumothorax developed in eight (17 percent) procedures, but only one procedure resulted in a pleural drainage; the incidence of other adverse effects was low and clinically irrelevant. Conclusion Our study suggests that TNA can be a useful technique in establishing the etiologic diagnosis of pulmonary infections in HIV-infected patients, with a good sensitivity, high specificity, and relatively low incidence of serious complications, with TNA appearing as a reliable alternative to more uncomfortable methods.
Zhen-guo Huang - One of the best experts on this subject based on the ideXlab platform.
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CT-guided Transthoracic needle biopsy of pulmonary lesions: comparison between the cutting needle and Aspiration needle.
The British journal of radiology, 2020Co-Authors: Zhen-guo Huang, Hongliang Sun, Cun-li Wang, Bao-xiang Gao, He Chen, Min-xing Yang, Xiao-liang ChenAbstract:OBJECTIVES To compare CT-guided Transthoracic cutting needle biopsy (TCNB) with Transthoracic Aspiration needle biopsy (TANB) for pulmonary lesions with respect to the diagnostic accuracy and complication rate. METHODS Of the 859 cases that underwent consecutive CT-guided biopsy of pulmonary lesions, 713 cases confirmed by surgical pathology or clinical follow-up were enrolled. Of these, the first consecutive 275 cases underwent TANB, and the remaining 438 received TCNB. The final diagnosis determined the accuracy of biopsy. Based on the post-biopsy CT and clinical medical records, the presence or absence of biopsy-related complications was determined. The χ2 test was used to compare the differences between TCNB and TANB in terms of diagnostic accuracy and complication rate. RESULTS Among the 713 biopsy lesions, the final diagnosis was malignant in 411 cases and benign in 302 cases. As compared to TANB, the diagnostic accuracy of TCNB (98.9% vs 93.8%, χ2 = 14.35, p < 0.01), sensitivity to malignant lesions (97.8% vs 90.6%, χ2 = 10.58, p < 0.01), negative predictive value (97.6% vs 84.8%, χ2 = 19.03, p < 0.01), and specific diagnostic rate for benign lesions (73.4% vs 57.9%, χ2 = 7.29, p < 0.01) were improved. On the other hand, a statistical difference was detected between TCNB and TANB with respect to the incidence of pneumothorax (20.6% vs 13.1%, χ2 = 6.46, p = 0.01), hemorrhage (32.2% vs 13.1%, χ2 = 33.03, p < 0.01), hemoptysis (8.2% vs 3.3%, χ2 = 6.87, p < 0.01). One patient died just several minutes after TCNB due to severe hemorrhage with hemoptysis. CONCLUSIONS Compared to TANB, CT-guided TCNB improves the diagnostic accuracy of pulmonary lesions, but complication rate increases significantly. ADVANCES IN KNOWLEDGE In general, TCNB should be recommended, especially for highly suspicious benign lesions. For patients with small lesions adjacent to vessels or vessels within the lesion, TANB should be considered.
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CT-guided Transthoracic needle biopsy of pulmonary lesions: comparison between the cutting needle and Aspiration needle
The British journal of radiology, 2020Co-Authors: Zhen-guo Huang, Hongliang Sun, Cun-li Wang, Bao-xiang Gao, He Chen, Min-xing Yang, Xiao-liang ChenAbstract:Objectives:To compare CT-guided Transthoracic cutting needle biopsy (TCNB) with Transthoracic Aspiration needle biopsy (TANB) for pulmonary lesions with respect to the diagnostic accuracy and compl...
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CT-guided percutaneous Transthoracic Aspiration biopsy of chest lesions: factors influencing the diagnostic accuracy
Zhonghua yi xue za zhi, 2002Co-Authors: Zhen-guo Huang, Xue-zhe Zhang, Wu WangAbstract:OBJECTIVE To investigate the factors influencing the diagnostic accuracy of CT-guided percutaneous Transthoracic Aspiration biopsy of chest lesions. METHODS Data of pathology and clinical follow-up of 224 patients who had undergone CT-guided percutaneous Transthoracic biopsy were collected. Univariate analysis and multivariate stepwise Logistic regression analysis were made to study the influence of the patient-related factors (sex, age, and presence of emphysema), lesion-related factors (histology, size, location, depth, and presence of cavity discovered by CT), and procedure factor (posture of patient during operation) on the diagnostic accuracy of CT-guided biopsy. RESULTS (1) One hundred and sixty-five lesions were diagnosed as malignant and 79 lesions as benign. The accuracy rate of CT-guided biopsy was 82.4% (201/244). Univariate analysis showed that the diagnostic accuracy rates of CT-guided biopsy for malignant and benign lesions were 88.5% and 69.6% respectively (chi(2) = 13.096, P < 0.01). The mean diameters of the lesions with correct diagnosis and of those misdiagnosed were 4.0 cm +/- 1.8 cm and 3.1 cm +/- 1.4 cm respectively (F = 8.805, P < 0.01). (2) Multivariate stepwise Logistic regression analysis showed that among the various factors only histology (regression coefficient = 0.320, Wald chi(2) = 7.126, P < 0.01) and size (regression coefficient = 1.114, Wald chi(2) = 4.951, P < 0.05) were significantly associated with diagnostic accuracy. CONCLUSION Histology and size of lesion are the determining factors for diagnostic accuracy of CT-guided transcutaneous thoracic needle Aspiration biopsy.
