The Experts below are selected from a list of 87 Experts worldwide ranked by ideXlab platform
Janusz Pawliszyn - One of the best experts on this subject based on the ideXlab platform.
-
speciation of trimethyllead and Triethyllead by in tube solid phase microextraction high performance liquid chromatography electrospray ionization mass spectrometry
Journal of Analytical Atomic Spectrometry, 2000Co-Authors: Zoltán Mester, Heather Lord, Janusz PawliszynAbstract:An analytical method has been developed for the determination of the trimethyl- (TML) and Triethyllead (TEL) species in aqueous samples. In-tube solid phase microextraction (SPME) and high-performance liquid chromatography (HPLC) are coupled to a quadrupole mass spectrometer (MS) using electrospray (ES) as an ionization interface. Optimization of the instrumental parameters is described, including the evaluation of three commercial GC capillaries for the in-tube SPME experiments. The elemental (208Pb+) and molecular forms TML and TEL (m/z 253 and 295, respectively) were monitored simultaneously to provide complete speciation information. Results from the in-tube SPME-HPLC-ESMS experiments indicate that complete separation and detection of TML and TEL can be achieved in less than 5 min. Precision is greater than 5% and estimated limits of detection are 11.3 and 12.6 ng ml−1, respectively, for TML and TEL at a solution flow rate of 450 µl min−1.
-
Electrospray mass spectrometry of trimethyllead and Triethyllead with in-tube solid phase microextraction sample introduction
Rapid communications in mass spectrometry : RCM, 1999Co-Authors: Zoltán Mester, Janusz PawliszynAbstract:A study of positive ionization electrospray mass spectrometry (ES-MS) was performed on trimethyllead (TML) and Triethyllead (TEL). The system consisted of in-tube solid phase microextraction (SPME) coupled directly to an electrospray mass spectrometer. Fragmentation patterns of compounds were observed by applying different fragmentation voltages. High voltages produced sufficient fragmentation to elucidate the dissociation of the trialkyllead compounds. Electrospray mass spectrometry has been shown to be a suitable detection system for organolead speciation. Applying fragmentation energy programming, it might be possible to obtain in parallel the molecular and atomic signals of lead compounds. Copyright © 1999 John Wiley & Sons, Ltd.
Zoltán Mester - One of the best experts on this subject based on the ideXlab platform.
-
speciation of trimethyllead and Triethyllead by in tube solid phase microextraction high performance liquid chromatography electrospray ionization mass spectrometry
Journal of Analytical Atomic Spectrometry, 2000Co-Authors: Zoltán Mester, Heather Lord, Janusz PawliszynAbstract:An analytical method has been developed for the determination of the trimethyl- (TML) and Triethyllead (TEL) species in aqueous samples. In-tube solid phase microextraction (SPME) and high-performance liquid chromatography (HPLC) are coupled to a quadrupole mass spectrometer (MS) using electrospray (ES) as an ionization interface. Optimization of the instrumental parameters is described, including the evaluation of three commercial GC capillaries for the in-tube SPME experiments. The elemental (208Pb+) and molecular forms TML and TEL (m/z 253 and 295, respectively) were monitored simultaneously to provide complete speciation information. Results from the in-tube SPME-HPLC-ESMS experiments indicate that complete separation and detection of TML and TEL can be achieved in less than 5 min. Precision is greater than 5% and estimated limits of detection are 11.3 and 12.6 ng ml−1, respectively, for TML and TEL at a solution flow rate of 450 µl min−1.
-
Electrospray mass spectrometry of trimethyllead and Triethyllead with in-tube solid phase microextraction sample introduction
Rapid communications in mass spectrometry : RCM, 1999Co-Authors: Zoltán Mester, Janusz PawliszynAbstract:A study of positive ionization electrospray mass spectrometry (ES-MS) was performed on trimethyllead (TML) and Triethyllead (TEL). The system consisted of in-tube solid phase microextraction (SPME) coupled directly to an electrospray mass spectrometer. Fragmentation patterns of compounds were observed by applying different fragmentation voltages. High voltages produced sufficient fragmentation to elucidate the dissociation of the trialkyllead compounds. Electrospray mass spectrometry has been shown to be a suitable detection system for organolead speciation. Applying fragmentation energy programming, it might be possible to obtain in parallel the molecular and atomic signals of lead compounds. Copyright © 1999 John Wiley & Sons, Ltd.
F Adams - One of the best experts on this subject based on the ideXlab platform.
-
simultaneous multi elemental speciation analysis of organometallic compounds by solid phase microextraction and multicapillary gas chromatography hyphenated to inductively coupled plasma time of flight mass spectrometry
Journal of Analytical Atomic Spectrometry, 2004Co-Authors: Petru Jitaru, Heidi Goenaga Infante, F AdamsAbstract:A simple, rapid and accurate method on the basis of solid phase microextraction (SPME) in combination with multicapillary gas chromatography (MCGC) hyphenated to inductively coupled plasma-time-of-flight mass spectrometry (ICP-TOFMS) was developed for simultaneous speciation analysis of 10 organometallic compounds of mercury (including inorganic mercury), tin and lead. Headspace SPME was used for extraction/preconcentration of the species from the sample after derivatization with sodium tetraethylborate and subsequent volatilization. Seven SPME fibers were compared in terms of extraction efficiency. A 65 µm polydimethylsiloxane/divinylbenzene fiber offered the best overall extraction efficiency. Using MCGC separation, a total chromatographic run time below 200 s was obtained. With ICP-TOFMS detection peak widths at half height (FWHM) down to 0.3 s were measured without spectral skew thanks to the simultaneous character of the mass spectrometer. Detection limits well below pg g−1 levels were obtained for trimethyllead (TML), dimethyllead (DML), trimethyltin (TMT), dimethyltin (DMT), monomethyltin (MMT), monobutyltin (MBT), dibutyltin (DBT) and tributyltin (TBT). Somewhat higher detection limits were obtained for methylmercury (MeHg, 1.3 pg g−1) and inorganic mercury (Hg2+, 2.0 pg g−1). For extraction/preconcentration of MeHg and Hg2+ the 75 µm carboxen/polydimethylsiloxane (CAR/PDMS) fiber is a better choice. The analytical precision (RSD, %) for 10 successive injections of a standard mixture containing 100 pg of each species was generally below 5%. Propylmercury (PrHg) was used as the internal standard for MeHg and Hg2+ as well as for lead species determination. The method was validated by the analysis of biological and road dust certified reference materials (CRMs).
Shiuhjen Jiang - One of the best experts on this subject based on the ideXlab platform.
-
hydride generation inductively coupled plasma mass spectrometric detection of lead compounds separated by liquid chromatography
Journal of Analytical Atomic Spectrometry, 1995Co-Authors: Hueihjen Yang, Shiuhjen JiangAbstract:A preliminary study of a hydride generation (HG) system as the sample introduction device for an inductively coupled plasma mass spectrometry (ICP-MS) system is described. Samples containing ionic lead compounds were subjected to chromatographic separation before injection into the hydride generator. The species studied included inorganic lead (PbII), trimethyllead and Triethyllead. The sensitivity, detection limits and repeatability of the liquid chromatography (LC) ICP-MS system with a hydride generator were comparable to, or better than, those of an LC–ICP-MS system with conventional pneumatic nebulization or other sample introduction techniques. The limits of detection for various lead species were in the range 0.6–6 ng l–1 of lead based on peak area. The concentration of lead compounds in the National Institute of Standards and Technology Standard Reference Material was determined. Lead(II) was the only species in this sample. The results obtained agreed with the certified value.
Ewa Ninio - One of the best experts on this subject based on the ideXlab platform.
-
Effects of organometals on cellular signaling. II. Inhibition of reincorporation of free arachidonic acid and influence on paf-acether synthesis by Triethyllead.
Environmental Health Perspectives, 1994Co-Authors: Harald F. Krug, Dorit Mattern, Jocelyne Bidault, Ewa NinioAbstract:Organometal compounds affect many enzymes, especially those containing SH-groups as acyl- and acetyltransferases involved in lysophospholipid reacylation. In HL-60 cells, organotin and -lead compou...
