The Experts below are selected from a list of 75972 Experts worldwide ranked by ideXlab platform
Marshall D Hatch - One of the best experts on this subject based on the ideXlab platform.
-
C(4) photosynthesis: discovery and resolution.
Photosynthesis research, 2002Co-Authors: Marshall D HatchAbstract:This Minireview provides a brief account of the scene and interesting Turn of Events surrounding the discovery and resolution of the mechanism of C(4) photosynthesis, as well as the recognition of the process by the wider plant science community.
-
C4 photosynthesis: discovery and resolution
Photosynthesis Research, 2002Co-Authors: Marshall D HatchAbstract:This Minireview provides a brief account of the scene and interesting Turn of Events surrounding the discovery and resolution of the mechanism of C4 photosynthesis, as well as the recognition of the process by the wider plant science community. Abbreviations: PCR – photosynthetic carbon reduction; 3-PGA – 3-phosphoglyceric acid; PEP – phosphoenolpyruvate
Piotr Sobieszczyk - One of the best experts on this subject based on the ideXlab platform.
-
A Shocking Turn of Events
The New England journal of medicine, 2018Co-Authors: Ersilia M. Defilippis, Anand Vaidya, David A. Braun, Neal K. Lakdawala, Piotr SobieszczykAbstract:A Shocking Turn of Events This interactive case features a 38-year-old woman with symptoms of an upper respiratory infection, shortness of breath, and palpitations. An ECG showed abnormal findings. Test your diagnostic and therapeutic skills at NEJM.org.
Michael N. Hall - One of the best experts on this subject based on the ideXlab platform.
-
An Amazing Turn of Events
Cell, 2017Co-Authors: Michael N. HallAbstract:How the master regulator of cell growth, TOR, came to be identified and understood, from the perspective of its discoverer, Michael N. Hall.
C. Yan Cheng - One of the best experts on this subject based on the ideXlab platform.
-
Breast cancer resistance protein (Bcrp) and the testis--an unexpected Turn of Events.
Asian journal of andrology, 2013Co-Authors: Xiaojing Qian, Yan-ho Cheng, Dolores D Mruk, C. Yan ChengAbstract:Breast cancer resistance protein (Bcrp) is an ATP-dependent efflux drug transporter. It has a diverse spectrum of hydrophilic and hydrophobic substrates ranging from anticancer, antiviral and antihypertensive drugs, to organic anions, antibiotics, phytoestrogens (e.g., genistein, daidzein, coumestrol), xenoestrogens and steroids (e.g., dehydroepiandrosterone sulfate). Bcrp is an integral membrane protein in cancer and normal cells within multiple organs (e.g., brain, placenta, intestine and testis) that maintains cellular homeostasis by extruding drugs and harmful substances from the inside of cells. In the brain, Bcrp is a major component of the blood–brain barrier located on endothelial cells near tight junctions (TJs). However, Bcrp is absent at the Sertoli cell blood–testis barrier (BTB); instead, it is localized almost exclusively to the endothelial TJ in microvessels in the interstitium and the peritubular myoid cells in the tunica propria. Recent studies have shown that Bcrp is also expressed stage specifically and spatiotemporally by Sertoli and germ cells in the seminiferous epithelium of rat testes, limited only to a testis-specific cell adhesion ultrastructure known as the apical ectoplasmic specialisation (ES) in stage VI–early VIII tubules. These findings suggest that Bcrp is equipped by late spermatids and Sertoli cells to protect late-stage spermatids completing spermiogenesis. Furthermore, Bcrp was found to be associated with F (filamentous)-actin and several actin regulatory proteins at the apical ES and might be involved in the organisation of actin filaments at the apical ES in stage VII–VIII tubules. These findings will be carefully evaluated in this brief review.
-
Regulation of blood-testis barrier dynamics by focal adhesion kinase (FAK): an unexpected Turn of Events.
Cell cycle (Georgetown Tex.), 2009Co-Authors: C. Yan Cheng, Dolores D MrukAbstract:The blood-testis barrier (BTB) is conferred by co-existing tight junctions (TJs), basal ectoplasmic specialization (basal ES), desmosome-like junctions and gap junctions (GJs) between adjacent Sertoli cells near the basement membrane in the seminiferous epithelium. While the concept of the BTB has been known for more than a century and its significance to spermatogenesis discerned for more than five decades, its regulation has remained largely unknown. Recent studies, however, have demonstrated that focal adhesion kinase (FAK), a modulator of the integrin-based signaling that plays a crucial role on cell movement, apoptosis, cell survival and gene expression at the focal adhesion complex (FAC, also known as focal contact, a cell-matrix anchoring junction type), is an integrated component of the BTB, associated with the TJ-integral membrane protein occludin and its adaptor zonula occludens-1 (ZO-1). Herein, we summarize recent findings in the field regarding the significance of FAK in conferring BTB int...
Ersilia M. Defilippis - One of the best experts on this subject based on the ideXlab platform.
-
A Shocking Turn of Events
The New England journal of medicine, 2018Co-Authors: Ersilia M. Defilippis, Anand Vaidya, David A. Braun, Neal K. Lakdawala, Piotr SobieszczykAbstract:A Shocking Turn of Events This interactive case features a 38-year-old woman with symptoms of an upper respiratory infection, shortness of breath, and palpitations. An ECG showed abnormal findings. Test your diagnostic and therapeutic skills at NEJM.org.
