The Experts below are selected from a list of 225708 Experts worldwide ranked by ideXlab platform
Lee A Dellon - One of the best experts on this subject based on the ideXlab platform.
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reconstruction of the human median nerve in the forearm with the neurotube
Microsurgery, 2007Co-Authors: B Nicholas S Donoghoe, Lee A Dellon, D Gedge M D RossonAbstract:Reconstruction of the median nerve in the forearm traditionally has required multiple interfascicular interposition autologous nerve grafts. Recovery of Two-Point Discrimination, even in young adults, has been reported rarely. Two patients, aged 43 and 61, are reported with 5-year follow-up of median nerve reconstruction in the distal forearm in which multiple interposition bioabsorbable polyglycolic acid conduits (Neurotube) were used to bridge the 3-cm nerve defects. Four separate 2.3-mm diameter, 4.0-cm long conduits were used in each patient. Sensory re-education was used for rehabilitation. Each patient recovered Two-Point Discrimination with good localization in the thumb, index, and middle finger by 2 years after the nerve reconstruction. Both patients recovered abductor pollicis brevis function.
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human pressure perception values for constant and moving one and two point Discrimination
Plastic and Reconstructive Surgery, 1992Co-Authors: Evan S Dellon, Robin Mourey, Lee A DellonAbstract:Despite the need to evaluate sensibility for accurate diagnosis and the need to record the degree of sensation achieved in the postoperative period, the clinician has been without the ability to measure human pressure perception accurately. Traditionally, the Semmes-Weinstein monofilaments were used to measure the static one-point Discrimination threshold. A new sensory testing instrument, the Pressure-Specifying Sensory Device, was used to obtain normative data from the index and little finger of the dominant hand in 35 people ranging in age from 16 to 83 with no known neurologic impairment. Pressure perceptions for static one- and Two-Point Discrimination (s1PD, s2PD) and moving one- and Two-Point Discrimination (m1PD, m2PD) were recorded. The mean values (+/- SD) were 0.13 +/- 0.06, 0.24 +/- 0.12, 0.22 +/- 0.10, and 0.26 +/- 0.13 gm/mm2 for s1PD, s2PD, m1PD, and m2PD, respectively, on the index finger and 0.07 +/- 0.05, 0.16 +/- 0.12, 0.17 +/- 0.07, and 0.21 +/- 0.14 gm/mm2 for s1PD, s2PD, m1PD, and m2PD, respectively, for the little finger. The little finger was significantly more sensitive than the index finger (p less than 0.001). There was no significant change in pressure perception with increasing age.
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human pressure perception values for constant and moving one and two point Discrimination
Plastic and Reconstructive Surgery, 1992Co-Authors: Evan S Dellon, Robin Mourey, Lee A DellonAbstract:Despite the need to evaluate sensibility for accurate diagnosis and the need to record the degree of sensation achieved in the postoperative period, the clinician has been without the ability to measure human pressure perception accurately. Traditionally, the Semmes-Weinstein monofilaments were used to measure the static one-point Discrimination threshold. A new sensory testing instrument, the Pressure-Specifying Sensory Device, was used to obtain normative data from the index and little finger of the dominant hand in 35 people ranging in age from 16 to 83 with no known neurologic impairment
Zhe Zhang - One of the best experts on this subject based on the ideXlab platform.
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prospective evaluation of finger two point Discrimination and carpal tunnel syndrome among women with breast cancer receiving adjuvant aromatase inhibitor therapy
Breast Cancer Research and Treatment, 2019Co-Authors: Jennifer Y Sheng, Amanda Blackford, Aditya Bardia, Raghunandan Venkat, Gedge D Rosson, Jon T Giles, Daniel F Hayes, Stacie Jeter, Zhe ZhangAbstract:Aromatase inhibitors (AIs) are associated with musculoskeletal symptoms and risk of developing carpal tunnel syndrome (CTS), which can impair quality of life and prompt treatment discontinuation. The incidence of CTS and clinical utility of diagnostic tests such as 2-point Discrimination (2-PD) have not been prospectively examined among women receiving AIs. Postmenopausal women with stage 0-III hormone receptor-positive breast cancer who were enrolled in a randomized clinical trial investigating adjuvant AIs (Exemestane and Letrozole Pharmacogenetics, ELPh) underwent prospective evaluation of 2-PD with the Disc-criminator™ (sliding aesthesiometer) and completed a CTS questionnaire at baseline, 3, 6, and 12 months, following initiation of AI. Changes in mean 2-PD were analyzed with multivariable mixed effects modelling. A p value < 0.05 was considered statistically significant. Of 100 women who underwent baseline 2-PD testing, CTS was identified by questionnaire in 11% at baseline prior to AI initiation. Prevalence of CTS at any time in the first year was 26%. A significant increase in worst 2-PD score was observed from baseline to 3 months (3.7 mm to 3.9 mm, respectively, p = 0.03) when adjusted for age, prior chemotherapy, randomized treatment assignment, and diabetes. There were no significant differences in treatment discontinuation due to CTS between the arms. For women receiving adjuvant AI, 2-PD scores were significantly worse at 3 months compared to baseline. Studies are required to assess whether change in 2-PD is an adequate objective assessment for CTS with AI therapy. Early diagnosis of CTS may expedite management, improve AI adherence, and enhance breast cancer outcomes.
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prospective evaluation of finger two point Discrimination and carpal tunnel syndrome among women with breast cancer receiving adjuvant aromatase inhibitor therapy
Breast Cancer Research and Treatment, 2019Co-Authors: Jennifer Y Sheng, Aditya Bardia, Raghunandan Venkat, Gedge D Rosson, Jon T Giles, Daniel F Hayes, Stacie Jeter, Zhe Zhang, Amanda L BlackfordAbstract:Purpose Aromatase inhibitors (AIs) are associated with musculoskeletal symptoms and risk of developing carpal tunnel syndrome (CTS), which can impair quality of life and prompt treatment discontinuation. The incidence of CTS and clinical utility of diagnostic tests such as 2-point Discrimination (2-PD) have not been prospectively examined among women receiving AIs. Methods Postmenopausal women with stage 0-III hormone receptor-positive breast cancer who were enrolled in a randomized clinical trial investigating adjuvant AIs (Exemestane and Letrozole Pharmacogenetics, ELPh) underwent prospective evaluation of 2-PD with the Disc-criminator™ (sliding aesthesiometer) and completed a CTS questionnaire at baseline, 3, 6, and 12 months, following initiation of AI. Changes in mean 2-PD were analyzed with multivariable mixed effects modelling. A p value Results Of 100 women who underwent baseline 2-PD testing, CTS was identified by questionnaire in 11% at baseline prior to AI initiation. Prevalence of CTS at any time in the first year was 26%. A significant increase in worst 2-PD score was observed from baseline to 3 months (3.7 mm to 3.9 mm, respectively, p = 0.03) when adjusted for age, prior chemotherapy, randomized treatment assignment, and diabetes. There were no significant differences in treatment discontinuation due to CTS between the arms. Conclusion For women receiving adjuvant AI, 2-PD scores were significantly worse at 3 months compared to baseline. Studies are required to assess whether change in 2-PD is an adequate objective assessment for CTS with AI therapy. Early diagnosis of CTS may expedite management, improve AI adherence, and enhance breast cancer outcomes.
Takeshi Hirase - One of the best experts on this subject based on the ideXlab platform.
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homodigital artery flap reconstruction for fingertip amputation a comparative study of the oblique triangular neurovascular advancement flap and the reverse digital artery island flap
Journal of Hand Surgery (European Volume), 2015Co-Authors: S Usami, S Kawahara, Y Yamaguchi, Takeshi HiraseAbstract:This fingertip reconstruction study retrospectively compared sensory recovery and active range of motion outcomes in neurovascular island advancement and reverse digital artery island flaps. Seventeen oblique triangular flaps and 14 reverse digital artery island flaps were performed for nail bed level fingertip amputations (Ishikawa subzone II). There was no significant difference between the two procedures in the Semmes–Weinstein monofilament test and range of motion results. For static and moving Two-Point Discrimination tests, however, those with a reverse digital artery island flap required a longer period for sensory recovery compared to those with an oblique triangular advancement flap. This trend equilibrated at 12 months after surgery showing no significant difference in both static and moving Two-Point Discrimination tests between the procedures.
Dean G Sotereanos - One of the best experts on this subject based on the ideXlab platform.
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treatment of recurrent compressive neuropathy of peripheral nerves in the upper extremity with an autologous vein insulator
Journal of Hand Surgery (European Volume), 2001Co-Authors: Sokratis E Varitimidis, Dimitris G Vardakas, Felix Goebel, Dean G SotereanosAbstract:The treatment of entrapment neuropathy in the upper extremity with surgical decompression has generally provided good results. Recurrence of symptoms, however, is not uncommon and its management is both challenging and difficult. Nineteen patients with recurrent carpal tunnel and cubital tunnel syndrome were treated with the vein wrapping technique using the autogenous saphenous vein. The average number of surgeries before vein wrapping was 3.3. The mean patient age was 53 years (range, 28-75 years) and the mean follow-up period was 43 months (range, 24-78 months). All patients reported reduction in pain and the sensory disturbances secondary to the compression of the median or ulnar nerve. Two-Point Discrimination and electrodiagnostic findings also improved.
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recurrent compressive neuropathy of the median nerve at the wrist treatment with autogenous saphenous vein wrapping
Journal of Hand Surgery (European Volume), 2000Co-Authors: Sokratis E Varitimidis, Felix Riano, Dimitris G Vardakas, Dean G SotereanosAbstract:Recurrence of symptoms occurs in a significant number of patients after surgical decompression for carpal tunnel syndrome, and its management is both challenging and difficult. Fifteen patients with recurrent carpal tunnel syndrome were treated with a vein wrapping technique using the autologous saphenous vein. A total of 48 operations had been performed on these patients before wrapping the median nerve with a saphenous vein graft. At a mean follow-up of 43 months all patients reported significant pain relief and improvement in their sensory disturbances. Two-Point Discrimination and the findings of nerve conduction studies also improved.
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recalcitrant post surgical neuropathy of the ulnar nerve at the elbow treatment with autogenous saphenous vein wrapping
Journal of Reconstructive Microsurgery, 2000Co-Authors: Sokratis E Varitimidis, Felix Riano, Dean G SotereanosAbstract:: Surgical decompression or transposition is generally efficacious for cubital tunnel syndrome. However, recurrence is not rare and its management is both challenging and difficult. Four patients with refractory cubital tunnel syndrome were operated on with the vein-wrapping technique, using the autologous saphenous vein. A total of 16 operative procedures were performed on these patients prior to wrapping the ulnar nerve with a saphenous vein graft. The mean patient age was 43 years (range: 30 to 54 years) and the mean follow-up was 34 months (range: 24 to 44 months). All patients reported significant pain relief and improvement in sensation. Two-Point Discrimination and EMG findings also improved. This is the first study reporting long-term results of the vein-wrapping technique for the treatment of recalcitrant cubital tunnel syndrome.
S Usami - One of the best experts on this subject based on the ideXlab platform.
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homodigital artery flap reconstruction for fingertip amputation a comparative study of the oblique triangular neurovascular advancement flap and the reverse digital artery island flap
Journal of Hand Surgery (European Volume), 2015Co-Authors: S Usami, S Kawahara, Y Yamaguchi, Takeshi HiraseAbstract:This fingertip reconstruction study retrospectively compared sensory recovery and active range of motion outcomes in neurovascular island advancement and reverse digital artery island flaps. Seventeen oblique triangular flaps and 14 reverse digital artery island flaps were performed for nail bed level fingertip amputations (Ishikawa subzone II). There was no significant difference between the two procedures in the Semmes–Weinstein monofilament test and range of motion results. For static and moving Two-Point Discrimination tests, however, those with a reverse digital artery island flap required a longer period for sensory recovery compared to those with an oblique triangular advancement flap. This trend equilibrated at 12 months after surgery showing no significant difference in both static and moving Two-Point Discrimination tests between the procedures.
